5.4 The medical chemistry strategy

The strategy adopted was to start from first principles. Since prazosin is an alpha1 antagonist, it must compete with the agonist, noradrenaline, for the alpha1 receptor. So the Pfizer scientists decided to compare the structures of the two molecules and look for common structural features that might provide an insight into the way in which they bind to the receptor. One important observation was the fact that, at physiological pH, both compounds would be protonated, nor
Author(s): The Open University

License information
Related content

Copyright © 2013 The Open University

Virtual Maths - 2D Shapes, rectangle
Interactive simulation demonstrating calculation of area of a rectangle
Author(s): Leeds Metropolitan University

License information
Related content

http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

10.34 Numerical Methods Applied to Chemical Engineering (MIT)
Numerical methods for solving problems arising in heat and mass transfer, fluid mechanics, chemical reaction engineering, and molecular simulation. Topics: numerical linear algebra, solution of nonlinear algebraic equations and ordinary differential equations, solution of partial differential equations (e.g. Navier-Stokes), numerical methods in molecular simulation (dynamics, geometry optimization). All methods are presented within the context of chemical engineering problems. Familiarity with s
Author(s): Green Jr., William

License information
Related content

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative C

Darwin’s Compass: Why the evolution of humans is inevitable
Orthodox neo-Darwinism very much emphasises the random and contingent. Re-run the tape of life, as Steven Jay Gould famously observed, and the outcomes would be utterly different. Terrestrial life maybe, but certainly no humans. They, like tulips and tape-worms, are just another evolutionary fluke. The basis of this is hardly surprising: think of random mutations, massive shifts in the environment, not to mention the odd giant rock dropping out of the sky. Life is on a roller-coaster and is flun
Author(s): Creator not set

License information
Related content

Rights not set

3.3 Books and electronic books

Books are a good source of information. The publishing process (where a book is checked by an editor before publishing, and often reviewed by another author) means that books are reliable sources of information, although they may need to be evaluated for bias. A growing number of books can be found online.

Author(s): The Open University

License information
Related content

Copyright © 2013 The Open University

Revelations Sculpture from the RMIT Collection Panel, feat - Maria Fernanda Cardoso, Lisa Roet, Don
Sculptors Maria Fernanda Cardoso, Lisa Roet, Don Gore and Dan Wollmering are represented in the new RMIT Gallery exhibition Revelations: Sculpture From The RMIT Art Collection. In this panel they join exhibition curator Jon Buckingham to discuss stylistic and formal developments in sculpture and reflect on their own work.
Author(s): No creator set

License information
Related content

Virtual Cell Animations
The Virtual Cell site contains 20 different animations of cellular and molecular processes aimed at the introductory biology student. Each animation has a flash movie version or a step-by-step walk-through with a voice over explanation. A transcript of the voice over is available. There is a link to a set of Youtube versions of these videos.
Author(s): No creator set

License information
Related content

Online information retrieval: identification of measures that discriminate among users with differen
The major goal of this research was to discover those behaviors associated with the process of online bibliographic searching that are correlated with success. In the assumption that more experienced searchers are more successful, the major research objectives were to identify (1) the differences among the searches of users of online systems who have different amounts of overall experience and (2) the differences between the searches of persons with and without experience on the data base being
Author(s): Fenichel, Carol Hansen

License information
Related content

Rights not set

Public opinion and its liberal/anti-liberal critics: A reinterpretation of popular sovereignty in li
David Ragazzoni, DPhil student at Scuola Superiore Sant'Anna, delivers a talk for the Inaugural Oxford Graduate Conference in Political Theory. The conference theme was Political Theory and the Liberal Tradition.
Author(s): No creator set

License information
Related content

4 How to diagnose diabetes

Diabetes is a condition that results in an increased concentration of blood glucose and for diagnosis, accurate measurements of blood glucose levels are required. Blood glucose levels can be measured on different samples of blood. Sometimes the whole of the blood sample is used. This occurs when finger prick samples are measured on small personal meters. For more accurate measurements, the sample of blood is taken to a laboratory and the blood cells are removed. Measurements are then made on
Author(s): The Open University

License information
Related content

Copyright © 2013 The Open University

Survey of London: volume 38 - South Kensington Museums Area
At the core of this volume is a study of the estate in South Kensington and Westminster acquired under the auspices of Prince Albert by the Commissioners for the Great Exhibition of 1851, and developed as a remarkable cultural centre for the applied arts and sciences. In many ways the great sequence of world-famous institutions described here – such as the Victorian and Albert Museum, the National History Museum, the Royal Albert Hall, and the Imperial Institute – is a memorial to the Princ
Author(s): No creator set

License information
Related content

2.6.2 End-of-unit questions

Question 8

Express the following numbers using scientific (powers of ten) notation:

  • (a) 2.1 million

  • (b) 36 000

  • (c) 1/10

  • (d) 0.0000
    Author(s): The Open University

    License information
    Related content

    Copyright © 2013 The Open University

A Manual of Online Molecular Biology Techniques

Authors: 
Ed Rybicki