Data Safety Monitoring Boards: Their Place and Role in Trials
Dr Roma Chilengi, Head of Clinical Trials at the Kenya Medical Research Institute (KEMRI)/Wellcome Trust Research Programme in Kilifi, Kenya discusses clinical trial data safety monitoring boards (DSMBs). This introduction starts with a definition of a DSMB and discusses their roles and when they are required. DSMS constitutions, charters and considerations for under developed settings are also discussed.
How terrorism has invaded German law - Professor Thomas Weigend
Professor Thomas Weigend (University of Cologne). The threat of terrorism hit Germany in two waves, the first in the 1970s and 1980s, the second in the general context of 11 Sept., 2001. Both waves have led to extensive legislation in substantive and procedural criminal law. The 1970s saw the introduction of the new criminal offence of being a member of a terrorist organisation as well as ad hoc legislation cutting back on the rights of the defence. More recently, the powers of the State to use
The Visitors and Residents Principle: A guide to assessing motivations towards the web
An update to Prensky's 'Digital Natives' idea, taking the stand-point that individuals attitudes to the web are not primarily governed by age or technical skill. The original blog-post can be found here: http://tallblog.conted.ox.ac.uk/index.php/2008/07/23/not-natives-immigrants-but-visitors-residents/
Clinical Trial Protocol Development
Dr Phaik Yeong Cheah, Head of Clinical Trials at the Mahidol-Oxford Research Unit in Bangkok, Thailand discusses clinical trial protocol development. This lecture is an introduction to the topic and gives an overview from initial concept through to GCP requirements, ethical considerations, study drugs and procedures and safety reporting.
Introduction to Research Ethics
Dr Roma Chilengi, Head of Clinical Trials at the Kenya Medical Research Institute (KEMRI)/Wellcome Trust Research Programme in Kilifi, Kenya gives an introduction to research ethics. This overview covers the historical origins and landmark events that have influenced current understanding of research ethics. Some of the major ethical codes and fundamental ethical principles are identified and their application in research is discussed. Finally, there is an overview of the role of ethics committe
An Introduction to Clinical Trials
George Warimwe from the Kenya Medical Research Institute (KEMRI)/Wellcome Trust Research Programme in Kilifi, Kenya presents an introduction to clinical trials aimed at trial site staff and anyone new to the field. Topics covered include: equipoise and hypothesis, protocol, trial design, comparative effectiveness, pharmacovigilance, ICH-GCP basics, informed consent, essential documents, databases and statistics.
Ruth Rendell interviewed by David Grylls
Acclaimed crime writer Ruth Rendell discusses with David Grylls, Director of Studies, Literature and Creative Writing, the latest edition of the Penguin Complete Sherlock Holmes, for which she has supplied the introduction.
Symbols of Culture
PTPI's Global Youth Murals Project poses a wonderful introduction to the ways in which children around the world represent their cultures through visual art. Using this collection in the Global Gallery, learners can examine different depictions of culture as an entry point to studying cultures of countries around the world. This activity can be an introductory exercise to social studies or world geography research projects.
Setting Goals, Building Solutions
In this lesson, students consider the value of setting goals for themselves and for their community, thinking critically about the idea of defining community and shared interests and concerns. This is an introduction to the concepts that underlie the Millennium Development Goals.
Biometrics
This text manual introduces statistical analysis and its underlying philosophy, enabling students to understand how to describe the confidence they have in their analysis.
Statistical analysis is one of the most widely used, and abused, techniques in the biological sciences. Statistics are ostensibly used to allow an investigator to be objective. That is, the researcher uses statistical tests to determine whether or not his/her hypothesis is supported by the data collected.
Unfortunately, the
Learning to Think Mathematically
Concerned that most students leave college thinking of mathematics as a fixed body of knowledge to be memorized, Cooperstein designed a new course to help students learn to think mathematically for themselves. This website serves as a course portfolio that documents the new class, Introduction to Mathematical Problem Solving. The principal activity in the class involved students working on and discussing novel problems which required them to formulate experiments, work out cases, look for patter
Understanding cancer: News from the frontline
This Oxford at Said seminar was dedicated to cancer research. Three researchers from the University of Oxford give insights into recent advances in the field of cancer cell biology, therapy and epidemiology. One in three people develop cancer, and one in five in Europe and North America die of the disease. Although environmental and lifestyle factors, for example smoking or sun exposure, affect the incidence of some cancer types, all human populations and many types of animal suffer from this di
18.05 Introduction to Probability and Statistics (MIT)
This course provides an elementary introduction to probability and statistics with applications. Topics include: basic probability models; combinatorics; random variables; discrete and continuous probability distributions; statistical estimation and testing; confidence intervals; and an introduction to linear regression.
Detection of Genetically Modified Foods
Genetically modified foods are often in the news and widely grown in the United States. Three US government agencies (USDA, FDA, and EPA) work to regulate the introduction and production of genetically modified foods. These crops can provide agricultural, ecological and nutritional benefits, but there are also potential risks to the environment and consumers. As consumers and public interest groups around the world have become aware of these risks, there has been a call for more explicit product
An Introduction to DNA: Spectrophotometry, Degradation, and the 'Frankengel' Experiment
In this laboratory students perform three exercises as an introduction to the basics of handling and analyzing DNA. In the first, they expose circular plasmid, linear phage, and high molecular weight genomic DNA samples to a variety of physical, thermal, chemical, and enzymatic conditions that might be expected to affect DNA integrity. The DNA's are analyzed by electrophoresis on a group agarose gel. In the second, they pour and reconstruct a "Frankengel" (a gel containing sections with three di
Complex numbers
You may have met complex numbers before, but not had experience in manipulating them. This unit gives an accessible introduction to complex numbers, which are very important in science and technology, as well as mathematics. The unit includes definitions, concepts and techniques which will be very helpful and interesting to a wide variety of people with a reasonable background in algebra and trigonometry.
Introduction to Adobe Director
A set of training videos including commentary and animation made with Camtasia. These videos take you through an introduction to Adobe Director using Lingo.
8.01T Physics I (MIT)
This freshman-level course is an introduction to classical mechanics. The subject is taught using the TEAL (Technology Enabled Active Learning) format which features small group interaction via table-top experiments utilizing laptops for data acquisition and problem solving workshops. Acknowledgements The TEAL project is supported by The Alex and Brit d'Arbeloff Fund for Excellence in MIT Education, MIT iCampus, the Davis Educational Foundation, the National Science Foundation, the Class of 1960
10.492-2 Integrated Chemical Engineering Topics I: Introduction to Biocatalysis (MIT)
This course provides a brief introduction to the field of biocatalysis in the context of process design. Fundamental topics include why and when one may choose to use biological systems for chemical conversion, considerations for using free enzymes versus whole cells, and issues related to design and development of bioconversion processes. Biological and engineering problems are discussed as well as how one may arrive at both biological and engineering solutions.
Transport Processes in the Environment, Fall 2004
Introduction to momentum and scalar transport in environmental flows, with emphasis given to river and lake systems. Derivation and solutions to the differential form of mass conservation equations. Topics include: molecular and turbulent diffusion, boundary layers, dissolution, phase partitioning, bed-water exchange, air-water exchange, settling and coagulation, buoyancy-driven flows, and stratification in lakes.
