Associate Professor of Pharmacology, Faculty of Medicine & Health Sciences
The major interest of our group is in understanding the role of bi-directional communication between neurons and glia in brain physiology. Specifically, we are interested in how information contained… read more
The major interest of our group is in understanding the role of bi-directional communication between neurons and glia in brain physiology. Specifically, we are interested in how information contained in neuronal network activity is encoded by astrocytes into calcium signals, with particular emphasis on the importance of kinetics in signal transduction. To that end, we use the cerebellum - a region of the brain involved in motor coordination and learning - to study the spatiotemporal properties of the glutamate and nitric oxide signalling pathways in astrocytes. We are also interested in the consequences of astrocyte calcium signalling on neuronal network function, focussing on how astrocytes can modulate synaptic strength.
University of NottinghamMedical School Queen's Medical CentreNottingham NG7 2UH
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