Life Sciences

We cover a wide spectrum of biological and medical sciences in both teaching and research. Expertise in the school spans molecular and cell biology, biochemistry, genetics, microbiology, pharmacology, physiology, anatomy and zoology.

Our aim is to achieve excellence in education, both with our undergraduate and postgraduate courses, and with the major contributions we make to professional courses in medicine, pharmacy and dietetics.

We also have a substantial research portfolio and strive to achieve research excellence across this range.

Biochemistry students working on an experiment in the lab.

Themes

Publications

Human Adaptation of Ebola Virus during the West African Outbreak

Description: Richard A. Urbanowicz, C. Patrick McClure, Anavaj Sakuntabhai, Amadou A. Sall, Gary Kobinger 13,14, Marcel A. Müller, Edward C. Holmes, Félix A. Rey, Etienne Simon-Loriere, Jonathan K. Ball

A Diverse Panel of Hepatitis C Virus Glycoproteins for Use in Vaccine Research Reveals Extremes of Monoclonal Antibody Neutralization Resistance

Description: Urbanowicz RA, McClure CP, Brown RJ, Tsoleridis T, Persson MA, Krey T, Irving WL, Ball JK, Tarr AW

High resolution sequencing of hepatitis C virus reveals limited intra-hepatic compartmentalization in end-stage liver disease

Description: Hedegaard DL, Tully DC, Rowe IA, Reynolds GM, Bean DJ, Hu K, Davis C, Wilhelm A, Ogilvie CB, Power KA, Tarr AW, Kelly D, Allen TM, Balfe P, McKeating JA

STAT2 Is a Pervasive Cytokine Regulator due to Its Inhibition of STAT1 in Multiple Signaling Pathways

Description: Johnathan Ho, Christin Pelzel, Andreas Begitt, Maureen Mee, Hany M. Elsheikha, David J. Scott, Uwe Vinkemeier

Formin Is Associated with Left-Right Asymmetry in the Pond Snail and the Frog

Antibody-Mediated Inhibition of the FGFR1c Isoform induces a Catabolic Lean State Siberian Hamsters

Description: Samma RJ, Lewis JE, Lory A, Fowler MJ, Cooper S, Warner A, Emmerson P, Adams AC, Luckett JC, Perkins AC, Wilson D, Barrett P, Tsintzas K, Eblinh FJ

Primordial germ cells: the first lineage or the last cells standing

Description: Andrew D. Johnson and Ramiro Alberio

Impact of voluntary exercise and housing conditions on hippocampal glucocorticoid receptor, miR-124 and anxiety

Description: Pan-Vazquez, A. Rye, N. Ameri, M. McSparron, B. Smallwood, G. Bickerdyke, J. Rathbone, A. Dajas-Bailador, F and Toledo-Rodriguez, M.

Contribution of serotonin and dopamine to changes in core body temperatue and locomotor activity in rates following repeated administration of mephedrone

Description: Sinead E. Shortall, Clare H. Spicer, Francis J.P. Ebling, A. Richard Green, Kevin C.F. Fone and Madeleine V.King.

Mitotic activity of survivin is regulated by acetylation at K129

Description: Aljaberi AM, Webster JR, Wheatley SP.

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News

Biohacking with Matt Loose and Jonathan Ball

No monsters, but wonders

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Athena SWAN

Athena SWAN awards champion good working practices to advance the representation of women in science, technology, engineering, medicine and mathematics. The school was awarded Athena SWAN Silver Status in 2013 and we successfully renewed this in 2017.

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