Christopher Merrett

Contact

• workBoots Science Building
  University Park
  Nottingham
  NG7 2RD
  UK
• Christopher.Merrett1@nottingham.ac.uk

Biography

I graduated with an MSci (Hons) in Chemistry from the University of Nottingham in 2018, during which time I undertook collaborative research projects with GlaxoSmithKline in the development of novel therapeutics. I returned to the University of Nottingham to carry out my PhD studies at the Biodiscovery Institute in 2019 where I worked under the supervision of Prof. Neil R. Thomas and Prof. Cathy L. R. Merry. My PhD research, funded by the BBSRC, focused on the use of bio-orthogonal chemistry to develop in situ "click" chemical functionalisation of self-assembling peptide hydrogels. This was in the hope of creating customisable, more tissue-relevant and predictive 3D cell culture in vitro models for furthering our understanding in disease and developmental biology. During this time, I contributed to the masters course 'ONCG4023: translational technologies for stem cells' where I delivered a taught module on 'adding functionality to biomaterials'. For several years, I demonstrated in the School of Chemistry undergraduate organic lab modules and designed and supervised undergraduate research projects.

Expertise Summary

Organic chemistry; Bioconjugation and bioconjugative techniques; Bio-orthogonal and "click" chemistry; Biochemistry; Hydrogels and biomaterials; Glycobiology; Recombinant protein production; Mammalian cell culture and 3D techniques; Medicinal chemistry.

Recent Publications

• BARNES, LYDIA, BLABER, HOLLIE, BROOKS, DAVID T K, BYERS, LEWIS, BUCKLEY, DANIEL, BYRON, ZOE C, CHILVERS, RICHARD G, COCHRANE, LIAM, COONEY, EDWARD, DAMIAN, HEATHER A, FRANCIS, LUKE, FU HE, DANIEL, GRACE, JACK M J, GREEN, HARLEY J, HOGARTH, EDMUND J P, JUSU, LEYLA, KILLALEA, C ELIZABETH, KING, OLIVER, LAMBERT, JOSEPH, LEE, ZOE J, LIMA, NURIA S, LONG, CHRISTINA L, MACKINNON, MAY-LI, MAHDY, SHUSHA, MATTHEWS-WRIGHT, JOLYON, MILLWARD, MAKENZIE J, MEEHAN, MATTHEW F, MERRETT, CHRISTOPHER, MORRISON, LISA, PARKE, HAL R I, PAYNE, CHARLOTTE, PAYNE, LAWRENCE, PIKE, CRAIG, SEAL, ALEXANDER, SENIOR, AARON J, SMITH, KEENAN M, STANELYTE, KAMILE, STILLIBRAND, JOE, SZPARA, RACHEL, TADAY, FREYA F H, THREADGOULD, ANTONY M, TRAINOR, ROHAN J, WATERS, JORDAN, WILLIAMS, OLIVER, WONG, CARRIE K W, WOOD, KATHERINE, BARTON, NICK, GRUSZKA, ANNA, HENLEY, ZOE, ROWEDDER, JAMES E, COOKSON, ROSA, JONES, KATHERINE L, NADIN, ALAN, SMITH, IAN E, MACDONALD, SIMON J F and NORTCLIFFE, ANDREW, 2019. Free–Wilson Analysis of Comprehensive Data on Phosphoinositide-3-kinase (PI3K) Inhibitors Reveals Importance of N-Methylation for PI3Kδ Activity: Journal of Medicinal Chemistry Journal of Medicinal Chemistry. 62, 10402-10422

• View all publications

• BARNES, LYDIA, BLABER, HOLLIE, BROOKS, DAVID T K, BYERS, LEWIS, BUCKLEY, DANIEL, BYRON, ZOE C, CHILVERS, RICHARD G, COCHRANE, LIAM, COONEY, EDWARD, DAMIAN, HEATHER A, FRANCIS, LUKE, FU HE, DANIEL, GRACE, JACK M J, GREEN, HARLEY J, HOGARTH, EDMUND J P, JUSU, LEYLA, KILLALEA, C ELIZABETH, KING, OLIVER, LAMBERT, JOSEPH, LEE, ZOE J, LIMA, NURIA S, LONG, CHRISTINA L, MACKINNON, MAY-LI, MAHDY, SHUSHA, MATTHEWS-WRIGHT, JOLYON, MILLWARD, MAKENZIE J, MEEHAN, MATTHEW F, MERRETT, CHRISTOPHER, MORRISON, LISA, PARKE, HAL R I, PAYNE, CHARLOTTE, PAYNE, LAWRENCE, PIKE, CRAIG, SEAL, ALEXANDER, SENIOR, AARON J, SMITH, KEENAN M, STANELYTE, KAMILE, STILLIBRAND, JOE, SZPARA, RACHEL, TADAY, FREYA F H, THREADGOULD, ANTONY M, TRAINOR, ROHAN J, WATERS, JORDAN, WILLIAMS, OLIVER, WONG, CARRIE K W, WOOD, KATHERINE, BARTON, NICK, GRUSZKA, ANNA, HENLEY, ZOE, ROWEDDER, JAMES E, COOKSON, ROSA, JONES, KATHERINE L, NADIN, ALAN, SMITH, IAN E, MACDONALD, SIMON J F and NORTCLIFFE, ANDREW, 2019. Free–Wilson Analysis of Comprehensive Data on Phosphoinositide-3-kinase (PI3K) Inhibitors Reveals Importance of N-Methylation for PI3Kδ Activity: Journal of Medicinal Chemistry Journal of Medicinal Chemistry. 62, 10402-10422