School of Life Sciences
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Gareth Hathway

Associate Professor of Neuroscience, Faculty of Medicine & Health Sciences

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Biography

I have a PhD from The University of Cambridge and a BSc (Hons) form the University of Cardiff in Pharmacology.

Expertise Summary

My research expertise is in the science of pain and nociception. Specifically I study the changing way in which the brain and spinal cord detect and processes pain from birth until adulthood and the way in which changes in the immune system impact upon this.

Teaching Summary

Teaching is something that I really enjoy and is an important part of my life as an academic.

I teach on the Neuroscience BSc (Hons) and MSci (Hons) degree courses .Along with my colleagues in the Neuroscience Teaching Group we have recently completely re-designed the neuroscience curriculum over the last 4 years. I have led on the redesign of the second and final years of the degree where we have introduced a range of new modules which promote small group teaching wherever possible, equipping our students with key skills which are transferable to the world of work as well as academic knowledge about neuroscience.

I currently convene Higher Skills in Neuroscience (Year 2), as well as Advanced Skills in Neuroscience (Final Year) and Sensational Neuroscience (Final Year). I also offer research projects to final year students and act as a personal tutor to students across all years.

From academic year 2019/20 I will take up the role as Director of Neuroscience Degrees.

I was awarded the Lord Dearing Award for Innovation and Excellence in Teaching in 2015.

Research Summary

My research group is sited within newly refurbished and equipped laboratories within the School of Life Sciences at the University of Nottingham. The broad focus of my research is to understand the… read more

Selected Publications

Current Research

My research group is sited within newly refurbished and equipped laboratories within the School of Life Sciences at the University of Nottingham. The broad focus of my research is to understand the underlying neurobiological processes that occur when an individual experiences pain.

My group uses a range of approaches to investigate the changes that occur in the brain, spinal cord and the immune system ranging from in vivo to cell based assays. We have recently pioneered the development of a new way of investigating the processes that take place in spinal cord neural networks which is shedding new light on the way in which we detect and process painful stimuli across the life-course. We have world-leading expertise in multi-electrode array electrophysiology, animal behaviour, neuropharmacology and utilise neuroanatomical and transcriptomic approaches to supplement these approaches. In addition we also collaborate closely with colleagues using imaging technologies to assess human and small animal neurophysiological approaches.

Current projects include

The role of the PAG in the maturation of spinal pain processing in early life

Neural stem cell niches in the spinal cord and the impact of early life pain

Endogenous pain control systems in health and disease

The impact of pain on cognitive flexibility

The changing relationship between neural and immune systems in early life

Dorsal horn pain processing in later life

The roles of miRNA in sensory neuron function

Astrocyte activation mechanisms in the spinal cord

Nuclear receptor programming of neonatal and adult spinal microglia

We are always seeking new colleagues to collaborate with from early career researchers seeking to learn new skills to established groups wishing to share expertise

I collaborate with groups in the UK and abroad, including University of Oxford, University of Cambridge, UCL and University of Texas . I am a member of the Versus Arthritis National Pain Centre.

Future Research

I am currently developing projects looking at:

The role of microglia and astrocytes in the maturation of pain processing

The role of dorsal horn inhibitory networks in health and disease

The role of endogenous pain control systems in the function of spinal and supraspinal systems in health and disease

School of Life Sciences

University of Nottingham
Medical School
Queen's Medical Centre
Nottingham NG7 2UH

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