Associate Professor, Faculty of Medicine & Health Sciences
My research interests are the mechanisms and structures of proteins involved in transmembrane flux.
In particular, the group works on ATP binding cassette (ABC) transporters which are involved in multidrug efflux from cancer cells, and which are involved in the clinical drug resistance of many tumour types. We have a BBSRC funded project to investigate the pharmacology of ABCG2 in collaboration with Nicholas Holliday and Steve Briddon. We have strong collaborations with the group of Beth Coyle to understand the role played by ABC transporters in pediatric brain tumour drug drug resistance, and with the group of Richard Callaghan to understand the mechanism of human ABC proteins.
University of NottinghamMedical School
Queen's Medical CentreNottingham NG7 2UH
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