LEWIS JE, MONNIER C, MARSHALL H, FOWLER M, GREEN R, COOPER S, CHIOTELLIS A, LUCKETT J, PERKINS AC, COSKUN T, ADAMS AC, SAMMS RJ, EBLING FJP and TSINTZAS K, 2020. Whole-body and adipose tissue-specific mechanisms underlying the metabolic effects of fibroblast growth factor 21 in the Siberian hamster. Molecular metabolism. 31, 45-54 TSINTZAS K, JONES R, PABLA P, MALLINSON J, BARRETT DA, KIM DH, COOPER S, DAVIES A, TAYLOR T, CHEE C, GAFFNEY C, VAN LOON LJC and STEPHENS FB, 2020. Effect of acute and short-term dietary fat ingestion on postprandial skeletal muscle protein synthesis rates in middle-aged, overweight, and obese men. American journal of physiology. Endocrinology and metabolism. 318(3), E417-E429 TEMPLEMAN, IAIN, REEVES, SUE, WALHIN, JEAN-PHILIPPE, SMITH, HARRY, CARROLL, HARRIET, ROGERS, PETER J., BRUNSTROM, JEFFREY M., KARAGOUNIS, LEONIDAS G., TSINTZAS, KOSTAS, THOMPSON, DYLAN, GONZALEZ, JAVIER and BETTS, JAMES A., 2019. Impact of Intermittent Fasting on Energy Balance and Associated Health Outcomes in Lean Adults MEDICINE AND SCIENCE IN SPORTS AND EXERCISE. 51(6), 796-796 LEWIS JE, EBLING FJP, SAMMS RJ and TSINTZAS K, 2019. Going Back to the Biology of FGF21: New Insights. Trends in endocrinology and metabolism. 30(8), 491-504 DAVIES A, NIXON A, MUHAMMED R, TSINTZAS K, KIRKHAM S, STEPHENS FB and MORAN GW, 2019. Reduced skeletal muscle protein balance in paediatric Crohn's disease. Clinical nutrition (Edinburgh, Scotland).
CHOWDHURY EA, RICHARDSON JD, GONZALEZ JT, TSINTZAS K, THOMPSON D and BETTS JA, 2019. Six Weeks of Morning Fasting Causes Little Adaptation of Metabolic or Appetite Responses to Feeding in Adults with Obesity. Obesity (Silver Spring, Md.). 27(5), 813-821 NICHOLSON T, CHURCH C, TSINTZAS K, JONES R, BREEN L, DAVIS ET, BAKER DJ and JONES SW, 2019. Vaspin promotes insulin sensitivity of elderly muscle and is upregulated in obesity. The Journal of endocrinology.
WILHELMSEN A, MALLINSON J, JONES R, COOPER S, TAYLOR T and TSINTZAS K, 2019. Chronic effects of high-intensity interval training on postprandial lipemia in healthy men. Journal of applied physiology (Bethesda, Md. : 1985). 127(6), 1763-1771 CARROLL HA, TEMPLEMAN I, CHEN YC, EDINBURGH RM, BURCH EK, JEWITT JT, POVEY G, ROBINSON TD, DOOLEY WL, JONES R, TSINTZAS K, GALLO W, MELANDER O, THOMPSON D, JAMES LJ, JOHNSON L and BETTS JA, 2018. Effect of acute hypohydration on glycemic regulation in healthy adults: a randomized crossover trial. Journal of applied physiology (Bethesda, Md. : 1985). 126(2), 422-430 O'LEARY MF, WALLACE GR, DAVIS ET, MURPHY DP, NICHOLSON T, BENNETT AJ, TSINTZAS K and JONES SW, 2018. Obese subcutaneous adipose tissue impairs human myogenesis, particularly in old skeletal muscle, via resistin-mediated activation of NFκB. Scientific reports. 8(1), 15360 MORAN, GORDON, WALKER, AMANDA, NIXON, ALINE, DEVADASON, DAVID, MUHAMMED, RAFEEQ, TSINTZAS, KOSTAS, KIRKHAM, SIAN and STEPHENS, FRANCIS, 2018. PAEDIATRIC CROHN'S DISEASE PATIENTS IN REMISSION HAVE A REDUCED SKELETAL MUSCLE PROTEIN BALANCE AFTER FEEDING GUT. 67, A59-A60 PARMAR B, LEWIS JE, SAMMS RJ, EBLING FJP, CHENG CC, ADAMS AC, MALLINSON J, COOPER S, TAYLOR T, GHASEMI R, STEPHENS FB and TSINTZAS K, 2018. Eccentric exercise increases circulating fibroblast activation protein α but not bioactive fibroblast growth factor 21 in healthy humans. Experimental physiology. 103(6), 876-883 PERRIN L, LOIZIDES-MANGOLD U, CHANON S, GOBET C, HULO N, ISENEGGER L, WEGER BD, MIGLIAVACCA E, CHARPAGNE A, BETTS JA, WALHIN JP, TEMPLEMAN I, STOKES K, THOMPSON D, TSINTZAS K, ROBERT M, HOWALD C, RIEZMAN H, FEIGE JN, KARAGOUNIS LG, JOHNSTON JD, DERMITZAKIS ET, GACHON F, LEFAI E and DIBNER C, 2018. Transcriptomic analyses reveal rhythmic and CLOCK-driven pathways in human skeletal muscle. eLife. 7, TEMPLEMAN I, THOMPSON D, GONZALEZ J, WALHIN JP, REEVES S, ROGERS PJ, BRUNSTROM JM, KARAGOUNIS LG, TSINTZAS K and BETTS JA, 2018. Intermittent fasting, energy balance and associated health outcomes in adults: study protocol for a randomised controlled trial. Trials. 19(1), 86 LEWIS JE, SAMMS RJ, COOPER S, LUCKETT JC, PERKINS AC, ADAMS AC, TSINTZAS K and EBLING FJP, 2017. Reduced adiposity attenuates FGF21 mediated metabolic improvements in the Siberian hamster. Scientific reports. 7(1), 4238 GAFFNEY CJ, MANSELL P, STEPHENS FB, MACDONALD IA and TSINTZAS K, 2017. Exercise Metabolism in Nonobese Patients with Type 2 Diabetes Following the Acute Restoration of Normoglycaemia. Journal of diabetes research. 2017, 8248725 SAMMS RJ, LEWIS JE, NORTON L, STEPHENS FB, GAFFNEY CJ, BUTTERFIELD T, SMITH D, CHENG C, PERFIELD JW, ADAMS AC, EBLING FJP and TSINTZAS K, 2017. FGF21 is an insulin-dependent postprandial hormone in adult humans. The Journal of clinical endocrinology and metabolism. 102, 3806-3813 LEWIS JE, SAMMS RJ, COOPER S, LUCKETT JC, PERKINS AC, DUNBAR JD, SMITH DP, EMMERSON PJ, ADAMS AC, EBLING FJP and TSINTZAS K, 2017. Antibody mediated targeting of the FGFR1c isoform increases glucose uptake in white and brown adipose tissue in male mice. Endocrinology. 158(10), 3090-3096 GONZALEZ JT, RICHARDSON JD, CHOWDHURY EA, KOUMANOV F, HOLMAN GD, COOPER S, THOMPSON D, TSINTZAS K and BETTS JA, 2017. Molecular adaptations of adipose tissue to 6 weeks of morning fasting vs. daily breakfast consumption in lean and obese adults. The Journal of physiology. 596(4), 609-622 ALGHANNAM, ABDULLAH F., JEDRZEJEWSKI, DAWID, TWEDDLE, MARK G., GRIBBLE, HANNAH, BILZON, JAMES, THOMPSON, DYLAN, TSINTZAS, KOSTAS and BETTS, JAMES A., 2016. Impact of Muscle Glycogen Availability on the Capacity for Repeated Exercise in Man MEDICINE AND SCIENCE IN SPORTS AND EXERCISE. 48(1), 123-131 CHOWDHURY, E. A., RICHARDSON, J. D., TSINTZAS, K., THOMPSON, D. and BETTS, J. A., 2016. Effect of extended morning fasting upon ad libitum lunch intake and associated metabolic and hormonal responses in obese adults INTERNATIONAL JOURNAL OF OBESITY. 40(2), 305-311 CHOWDHURY EA, RICHARDSON JD, HOLMAN GD, TSINTZAS K, THOMPSON D and BETTS JA, 2016. The causal role of breakfast in energy balance and health: a randomized controlled trial in obese adults. The American journal of clinical nutrition. 103(3), 747-56 BETTS, JAMES A., CHOWDHURY, ENHAD A., GONZALEZ, JAVIER T., RICHARDSON, JUDITH D., TSINTZAS, KOSTAS and THOMPSON, DYLAN, 2016. Is breakfast the most important meal of the day? PROCEEDINGS OF THE NUTRITION SOCIETY. 75(4), 464-474 SAMMS RJ, LEWIS JE, LORY A, FOWLER MJ, COOPER S, WARNER A, EMMERSON P, ADAMS AC, LUCKETT JC, PERKINS AC, WILSON D, BARRETT P, TSINTZAS K and EBLING FJP, 2015. Antibody-Mediated Inhibition of the FGFR1c Isoform Induces a Catabolic Lean State in Siberian Hamsters Current Biology. 25(22), 2997-3003 SAMMS, RICARDO J., MURPHY, MICHELLE, FOWLER, MAXINE J., COOPER, SCOTT, EMMERSON, PAUL, COSKUN, TAMER, ADAMS, ANDREW C., KHARITONENKOV, ALEXEI, EBLING, FRANCIS J. P. and TSINTZAS, KOSTAS, 2015. Dual effects of fibroblast growth factor 21 on hepatic energy metabolism JOURNAL OF ENDOCRINOLOGY. 227(1), 37-47 CHOWDHURY, ENHAD A., RICHARDSON, JUDITH D., TSINTZAS, KOSTAS, THOMPSON, DYLAN and BETTS, JAMES A., 2015. Carbohydrate-rich breakfast attenuates glycaemic, insulinaemic and ghrelin response to ad libitum lunch relative to morning fasting in lean adults BRITISH JOURNAL OF NUTRITION. 114(1), 98-107 STEPHENS, FRANCIS B., CHEE, CAROLYN, WALL, BENJAMIN T., MURTON, ANDREW J., SHANNON, CHRIS E., VAN LOON, LUC J. C. and TSINTZAS, KOSTAS, 2015. Lipid-Induced Insulin Resistance Is Associated With an Impaired Skeletal Muscle Protein Synthetic Response to Amino Acid Ingestion in Healthy Young Men DIABETES. 64(5), 1615-1620 STEPHENS FB, MENDIS B, SHANNON CE, COOPER S, ORTORI CA, BARRETT DA, MANSELL P and TSINTZAS K, 2014. Fish oil omega-3 fatty acids partially prevent lipid induced insulin resistance in human skeletal muscle without limiting acylcarnitine accumulation. Clinical science (London, England : 1979). 127(5), 315-22. SAMMS, RICARDO J., FOWLER, MAXINE J., COOPER, SCOTT, EMMERSON, PAUL, COSKUN, TAMER, ADAMS, ANDREW C., KHARITONENKOV, ALEXEI, TSINTZAS, KOSTAS and EBLING, FRANCIS J. P., 2014. Photoperiodic regulation of FGF21 production in the Siberian hamster HORMONES AND BEHAVIOR. 66(1), 180-185 BETTS JA, RICHARDSON JD, CHOWDHURY EA, HOLMAN GD, TSINTZAS K and THOMPSON D, 2014. The causal role of breakfast in energy balance and health: a randomized controlled trial in lean adults. The American journal of clinical nutrition. 100(2), 539-47 MURPHY, M., SAMMS, R., WARNER, A., BOLBOREA, M., BARRETT, P., FOWLER, M.J., BRAMELD, J.M., TSINTZAS, K., KHARITONENKOV, A., ADAMS, A.C., COSKUN, T. and EBLING, F.J.P., 2013. Increased responses to the actions of fibroblast growth factor 21 on energy balance and body weight in a seasonal model of adiposity Journal of Neuroendocrinology. 25(2), 180-189 TSINTZAS K, NORTON L, CHOKKALINGAM K, NIZAMANI N, COOPER S, STEPHENS F, BILLETER R and BENNETT A, 2013. Independent and combined effects of acute physiological hyperglycaemia and hyperinsulinaemia on metabolic gene expression in human skeletal muscle. Clinical science (London, England : 1979). 124(11), 675-84 BETTS, JA, THOMPSON, D, RICHARDSON, JD, CHOWDHURY, EA, JEANS, M, HOLMAN, GD and TSINTZAS, K, 2011. Bath Breakfast Project (Bbp) - Examining The Role Of Extended Daily Fasting In Human Energy Balance And Associated Health Outcomes: Study Protocol For A Randomised Controlled Trial [Isrctn31521726] Trials. 12, - TISDALE, PB, SEEVARATNAM, N, MACDONALD, IA, TSINTZAS, K and BENNETT, AJ, 2011. Skeletal Muscle Metabolic Gene Expression Is Not Affected By Dichloroacetate-Mediated Modulation Of Substrate Utilisation Annals Of Nutrition And Metabolism. 58(1), 19-24 KHOO, E.Y.H., WALLIS, J., TSINTZAS, K., MACDONALD, I.A. and MANSELL, P., 2010. Effects of exenatide on circulating glucose, insulin, glucagon, cortisol and catecholamines in healthy volunteers during exercise Diabetologia. 53(1), 139-143 STEPHENS, F.B., NORTON, L., JEWELL, K., CHOKKALINGAM, K., PARR, T. and TSINTZAS, K., 2010. Basal and insulin-stimulated pyruvate dehydrogenase complex activation, glycogen synthesis and metabolic gene expression in human skeletal muscle the day after a single bout of exercise Experimental Physiology. 95(7), 808-818 JANYACHAROEN, T, AUVICHAYAPAT, P, TSINTZAS, K, MACDONALD, IA and LEELAYUWAT, N, 2009. Effect of gender on fuel utilization during exercise at different intensities in untrained Thai individuals. European Journal of Applied Physiology. 107, 645-651 CHRISTODOULIDES, C., DYSON, P., SPRECHER, D., TSINTZAS, K. and KARPE, F., 2009. Circulating fibroblast growth factor 21 is induced by peroxisome proliferator-activated receptor agonists but not ketosis in man The Journal of Clinical Endocrinology and Metabolism. 94(9), 3594-3601 NORTON, L., PARR, T., CHOKKALINGAM, K., BARDSLEY, R.G., YE, H., BELL, G.I., PELSERS, M.M.A.L., VAN LOON, L.J.C. and TSINTZAS, K., 2008. Calpain-10 gene and protein expression in human skeletal muscle: Effect of acute lipid-induced insulin resistance and type 2 diabetes Journal of Clinical Endocrinology and Metabolism. 93(3), 992-998 BETTS, J.A., WILLIAMS, C., BOOBIS, L. and TSINTZAS, K., 2008. Increased carbohydrate oxidation after ingesting carbohydrate with added protein Medicine and Science in Sports and Exercise. 40(5), 903-912 FOSKETT, A., WILLIAMS, C., BOOBIS, L. and TSINTZAS, K., 2008. Carbohydrate availability and muscle energy metabolism during intermittent running Medicine and Science in Sports and Exercise. 40(1), 96-103 CHOKKALINGAM, K., TSINTZAS, K., SNAAR, J.E.M, NORTON, L., SOLANKY, B., LEVERTON, E., MORRIS, P., MANSELL, P. and MACDONALD, I.A., 2007. Hyperinsulinaemia during exercise does not suppress hepatic glycogen concentrations in patients with type 1 diabetes: a magnetic resonance spectroscopy study Diabetologia. 50(9), 1921-1929 CHOKKALINGAM, K., JEWELL, K., NORTON, L., LITTLEWOOD, L..J., VAN LOON, L.J.C., MANSELL, P., MACDONALD, I.A. and TSINTZAS, K., 2007. High fat/low carbohydrate diet reduces insulin-stimulated carbohydrate oxidation but stimulates non-oxidative glucose disposal in humans: an important role for skeletal muscle pyruvate dehydrogenase kinase 4 Journal of Clinical Endocrinology and Metabolism. 92(1), 284-292 CHOKKALINGAM,K., TSINTZAS,K., NORTON,L., JEWELL,K., MACDONALD,I.A. and MANSELL,P.I., 2007. Exercise under hyperinsulinaemic conditions increases whole-body glucose disposal without affecting muscle glycogen utilisation in type 1 diabetes. Diabetologia. 50(2), 414-421 TSINTZAS, K., CHOKKALINGAM, K., JEWELL, K., NORTON, L., MACDONALD, I.A. and CONSTANTIN-TEODOSIU, D., 2007. Elevated Free Fatty Acids Attenuate the Insulin-Induced Suppression of PDK4 Gene Expression in Human Skeletal Muscle: Potential Role of Intramuscular Long-Chain Acyl-CoAs. Journal of Clinical Endocrinology and Metabolism. 92(10), 3967-3972
BOONSONG, T, NORTON, L, CHOKKALINGAM, K, JEWELL, K, MACDONALD, I, BENNETT, A and TSINTZAS, K, 2007. Effect of exercise and insulin on SREBP-1c expression in human skeletal muscle: potential roles for the ERK1/2 and Akt signalling pathways. Biochemical Society Transactions. 35(Pt 5), 1310-1
NORTON, L., PARR, T., BARDSLEY, R. G., YE, H. and TSINTZAS, K., 2007. Characterization of GLUT4 and calpain expression in healthy human skeletal muscle during fasting and refeeding. Acta Physiologica (Oxford, England). 189(3), 233-40
PELSERS, M M A L, TSINTZAS, K, BOON, H, JEWELL, K, NORTON, L, LUIKEN, J J F P, GLATZ, J F C and VAN LOON, L J C, 2007. Skeletal muscle fatty acid transporter protein expression in type 2 diabetes patients compared with overweight, sedentary men and age-matched, endurance-trained cyclists. Acta physiologica (Oxford, England). 190(3), 209-19
TSINTZAS, K., JEWELL, K., KAMRAN, M., LAITHWAITE, D., BOONSONG, T., LITTLEWOOD, J., MACDONALD, I. and BENNETT, A., 2006. Differential regulation of metabolic genes in skeletal muscle during starvation and refeeding in humans. Journal of Physiology. 575(1), 291-303 LEELAYUWAT, N., TSINTZAS, K., PATEL, K. and MACDONALD, I.A., 2005. Metabolic responses to exercise after carbohydrate loads in healthy men and women Medicine and Science in Sports and Exercise. 37(10), 1721-7 TSINTZAS, K, SIMPSON, E J, SEEVARATNAM, N and JONES, S, 2003. Effect of exercise mode on blood glucose disposal during physiological hyperinsulinaemia in humans. European Journal of Applied Physiology. 89(2), 217-20 TSINTZAS, K, WILLIAMS, C, BOOBIS, L, SYMINGTON, S, MOOREHOUSE, J, GARCIA-ROVES, P and NICHOLAS, C, 2003. Effect of carbohydrate feeding during recovery from prolonged running on muscle glycogen metabolism during subsequent exercise. International Journal of Sports Medicine. 24(6), 452-8 TSINTZAS K, WILLIAMS C, CONSTANTIN-TEODOSIU D, HULTMAN E, BOOBIS L, CLARYS P and GREENHAFF P, 2001. Phosphocreatine degradation in type I and type II muscle fibres during submaximal exercise in man: effect of carbohydrate ingestion. The Journal of physiology. 537(Pt 1), 305-11 DIMOPOULOU, I, TSINTZAS, O K, ALIVIZATOS, P A and TZELEPIS, G E, 2001. Pattern of breathing during progressive exercise in chronic heart failure. International Journal of Cardiology. 81(2-3), 117-21; discussion 121-2 NICHOLAS, C W, TSINTZAS, K, BOOBIS, L and WILLIAMS, C, 1999. Carbohydrate-electrolyte ingestion during intermittent high-intensity running. Medicine and Science in Sports and Exercise. 31(9), 1280-6
DIMOPOULOU, I, TSINTZAS, O K, DAGANOU, M, COKKINOS, D V and TZELEPIS, G E, 1999. Contribution of lung function to exercise capacity in patients with chronic heart failure. Respiration; international review of thoracic diseases.. 66(2), 144-9
DIMOPOULOU, I, DAGANOU, M, TSINTZAS, O K and TZELEPIS, G E, 1998. Effects of severity of long-standing congestive heart failure on pulmonary function. Respiratory Medicine. 92(12), 1321-5
TSINTZAS, O K, WILLIAMS, C, BOOBIS, L and GREENHAFF, P, 1996. Carbohydrate ingestion and single muscle fiber glycogen metabolism during prolonged running in men. Journal of Applied Physiology. 81(2), 801-9
TSINTZAS, O K, WILLIAMS, C, WILSON, W and BURRIN, J, 1996. Influence of carbohydrate supplementation early in exercise on endurance running capacity. Medicine and Science in Sports and Exercise. 28(11), 1373-9 TSINTZAS, O K, WILLIAMS, C, BOOBIS, L and GREENHAFF, P, 1995. Carbohydrate ingestion and glycogen utilization in different muscle fibre types in man. Journal of Physiology. 489 ( Pt 1), 243-50 TSINTZAS, O K, WILLIAMS, C, SINGH, R, WILSON, W and BURRIN, J, 1995. Influence of carbohydrate-electrolyte drinks on marathon running performance. European Journal of Applied Physiology and Occupational Physiology. 70(2), 154-60
MAUGHAN, R J, GOODBURN, R, GRIFFIN, J, IRANI, M, KIRWAN, J P, LEIPER, J B, MACLAREN, D P, MCLATCHIE, G, TSINTSAS, K and WILLIAMS, C, 1993. Fluid replacement in sport and exercise--a consensus statement. British Journal of Sports Medicine. 27(1), 34-5
TSINTZAS, K, LIU, R, WILLIAMS, C, CAMPBELL, I and GAITANOS, G, 1993. The effect of carbohydrate ingestion on performance during a 30-km race. International Journal of Sport Nutrition and Exercise Metabolism. 3(2), 127-39