School of Life Sciences
 

Steve Briddon

PRINCIPAL RESEARCH FELLOW, Faculty of Medicine & Health Sciences

Contact

  • workRoom CS5 The University of Nottingham Medical School
    Queen's Medical Centre
    Nottingham
    NG7 2UH
    UK
  • work0115 82 30089
  • fax0115 82 30081

Biography

Steve is both a Principal Research Fellow at the University of Nottingham and since Sep 2024, Director of Pharmacology at Excellerate Bioscience. He has nearly 30 years' experience as a molecular pharmacologist, with a focus on the G protein-coupled receptors. His particular interest is in the spatio-temporal organisation of receptors at the subcellular level, and has spent much of the last 20 years developing advanced imaging and spectroscopy approaches to studying GPCR pharmacology in single cells. He is a Fellow of the British Pharmacological Society and the Royal Microscopical Society, as well as member of the Editorial board for Pharmacology Matters

Expertise Summary

  • Molecular Pharmacology of GPCRs (Quantitative Pharmacology, NanoBRET, TR-FRET)
  • Fluorescence Correlation Spectroscopy (FCS, FCCS, RICS, PCH)
  • Single cell pharmacology (binding and function)
  • Live cell confocal microscopy (fluorescent ligand binding, receptor trafficking)
  • Advanced imaging approaches (FLIM, FRAP)
  • Single cell calcium measurements
  • Second messenger assays (inositol phosphates, cAMP)

Selected Publications

School of Life Sciences

University of Nottingham
Medical School
Queen's Medical Centre
Nottingham NG7 2UH

e: life-sciences@nottingham.ac.uk
t: +44 (0)115 823 0141
f: +44 (0)115 823 0142