Stephen Gray

Contact

• workRoom D117
  Queen's Medical Centre
  Nottingham
  NG7 2UH
  UK
• work01158 230110
• Stephen.Gray@nottingham.ac.uk
• http://www.genomedynamics.co.uk

Biography

B.Sc. (Hons) Biology - University of Sussex

Associate of the Higher Education Academy

Ph.D. Biochemistry - in the lab of Prof. Matt Neale, Genome Damage and Stability Centre, University of Sussex. Thesis Title: Investigating the Molecular Mechanisms of Meiotic Recombination

MRC Centenary Award Postdoctoral Fellow - in the lab of Prof. Eva Hoffmann, - Genome Damage and Stability Centre, University of Sussex

PGCHe - University of Sussex

Fellow of the Higher Education Academy

Postdoctoral Research Fellow - in the lab of Prof. Matt Neale, - Genome Damage and Stability Centre, University of Sussex

Postdoctoral Associate and Research Associate - in the lab of Prof. Paula Cohen, Department of Biomedical Sciences and Center for Reproductive Genomics, Cornell University

Assistant Professor of Genome Dynamics - Division of Infections, Immunity and Microbes, School of Life Sciences, Faculty of Medicine & Health Sciences, University of Nottingham

Recent Publications

• GRAY S, SANTIAGO ER, CHAPPIE JS and COHEN PE, 2020. Cyclin N-Terminal Domain-Containing-1 Coordinates Meiotic Crossover Formation with Cell-Cycle Progression in a Cyclin-Independent Manner. Cell reports. 32(1), 107858
• TOLEDO M, SUN X, BRIEÑO-ENRÍQUEZ MA, RAGHAVAN V, GRAY S, PEA J, MILANO CR, VENKATESH A, PATEL L, BORST PL, ALANI E and COHEN PE, 2019. A mutation in the endonuclease domain of mouse MLH3 reveals novel roles for MutLγ during crossover formation in meiotic prophase I. PLoS genetics. 15(6), e1008177
• GRAY, S. and COHEN, P. E., 2016. Control of Meiotic Crossovers: From Double-Strand Break Formation to Designation: Annu Rev Genet Annu Rev Genet. 50, 175-210
• BRIENO-ENRIQUEZ, M. A., MOAK, S. L., TOLEDO, M., FILTER, J. J., GRAY, S., BARBERO, J. L., COHEN, P. E. and HOLLOWAY, J. K., 2016. Cohesin Removal along the Chromosome Arms during the First Meiotic Division Depends on a NEK1-PP1gamma-WAPL Axis in the Mouse: Cell Rep Cell Rep. 17(4), 977-986

• View all publications

• GRAY S, SANTIAGO ER, CHAPPIE JS and COHEN PE, 2020. Cyclin N-Terminal Domain-Containing-1 Coordinates Meiotic Crossover Formation with Cell-Cycle Progression in a Cyclin-Independent Manner. Cell reports. 32(1), 107858
• TOLEDO M, SUN X, BRIEÑO-ENRÍQUEZ MA, RAGHAVAN V, GRAY S, PEA J, MILANO CR, VENKATESH A, PATEL L, BORST PL, ALANI E and COHEN PE, 2019. A mutation in the endonuclease domain of mouse MLH3 reveals novel roles for MutLγ during crossover formation in meiotic prophase I. PLoS genetics. 15(6), e1008177
• GRAY, S. and COHEN, P. E., 2016. Control of Meiotic Crossovers: From Double-Strand Break Formation to Designation: Annu Rev Genet Annu Rev Genet. 50, 175-210
• BRIENO-ENRIQUEZ, M. A., MOAK, S. L., TOLEDO, M., FILTER, J. J., GRAY, S., BARBERO, J. L., COHEN, P. E. and HOLLOWAY, J. K., 2016. Cohesin Removal along the Chromosome Arms during the First Meiotic Division Depends on a NEK1-PP1gamma-WAPL Axis in the Mouse: Cell Rep Cell Rep. 17(4), 977-986
• GARCIA, V., GRAY, S., ALLISON, R. M., COOPER, T. J. and NEALE, M. J., 2015. Tel1(ATM)-mediated interference suppresses clustered meiotic double-strand-break formation: Nature Nature. 520(7545), 114-8
• COPSEY, A., TANG, S., JORDAN, P. W., BLITZBLAU, H. G., NEWCOMBE, S., CHAN, A. C., NEWNHAM, L., LI, Z., GRAY, S., HERBERT, A. D., ARUMUGAM, P., HOCHWAGEN, A., HUNTER, N. and HOFFMANN, E., 2013. Smc5/6 coordinates formation and resolution of joint molecules with chromosome morphology to ensure meiotic divisions: PLoS Genet PLoS Genet. 9(12), e1004071
• GRAY, S., ALLISON, R. M., GARCIA, V., GOLDMAN, A. S. and NEALE, M. J., 2013. Positive regulation of meiotic DNA double-strand break formation by activation of the DNA damage checkpoint kinase Mec1(ATR): Open Biol Open Biol. 3(7), 130019
• GARCIA, V., PHELPS, S. E., GRAY, S. and NEALE, M. J., 2011. Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1: Nature Nature. 479(7372), 241-4