Contact

• workApplied Health Research Building
  University Park
  Nottingham
  NG7 2RD
  UK
• work0115 74 86834
• Ralph.Akyea1@nottingham.ac.uk

Biography

Senior Research Fellow within the Primary Care Stratified Medicine Research Group.

Dr Akyea obtained his medical degree from the University of Ghana Medical School, master's degree in public health (MPH) and doctorate (PhD) in Primary Care from the University of Nottingham.

Expertise Summary

"Big Data" Research, Applied Epidemiology, Applied Statistics, Risk Prediction Modeling, Stratified/Precision Medicine, Public Health Research, Data Science (including machine learning approaches)

Research Summary

Primary research focuses on population health using large electronic health records and cohort data to understand disease heterogeneity and identify unique patient groups, with the aim of helping to… read more

Recent Publications

• QURESHI, S., LATIF, A., CONDON, L., AKYEA, R.K., KAI, J. and QURESHI, N., 2022. Understanding the barriers and enablers of pharmacogenomic testing in primary care: A qualitative systematic review with meta-aggregation synthesis. Pharmacogenomics. 23(2), 135-154
• IYEN, B., VINOGRADOVA, Y., AKYEA, R. K., WENG, S., QURESHI, N. and KAI, J., 2022. Ethnic disparities in mortality among overweight or obese adults with newly diagnosed type 2 diabetes: a population-based cohort study Journal of Endocrinological Investigation. Published Online: 13 January 2022,
• PERKINS, P., PARKINSON, A., HEBDON, R. and AKYEA, R.K., 2022. Behaviours of patients who take their strong opioids as unmeasured ‘sips’ Journal of Pain and Symptom Management. Accepted Version Online: 3 February 2022,
• AKYEA, R.K., VINOGRADOVA, Y., QURESHI, N., PATEL, R.S., KONTOPANTELIS, E., NTAIOS, G., ASSELBERGS, F.W., KAI, J. and WENG, S.F., 2021. Sex, age, and socioeconomic differences in non-fatal stroke incidence and subsequent major adverse outcomes. Stroke. 52(2), 396–405

• View all publications

Current Research

Primary research focuses on population health using large electronic health records and cohort data to understand disease heterogeneity and identify unique patient groups, with the aim of helping to tailor treatment/management strategies.

• QURESHI, S., LATIF, A., CONDON, L., AKYEA, R.K., KAI, J. and QURESHI, N., 2022. Understanding the barriers and enablers of pharmacogenomic testing in primary care: A qualitative systematic review with meta-aggregation synthesis. Pharmacogenomics. 23(2), 135-154
• IYEN, B., VINOGRADOVA, Y., AKYEA, R. K., WENG, S., QURESHI, N. and KAI, J., 2022. Ethnic disparities in mortality among overweight or obese adults with newly diagnosed type 2 diabetes: a population-based cohort study Journal of Endocrinological Investigation. Published Online: 13 January 2022,
• PERKINS, P., PARKINSON, A., HEBDON, R. and AKYEA, R.K., 2022. Behaviours of patients who take their strong opioids as unmeasured ‘sips’ Journal of Pain and Symptom Management. Accepted Version Online: 3 February 2022,
• AKYEA, R.K., VINOGRADOVA, Y., QURESHI, N., PATEL, R.S., KONTOPANTELIS, E., NTAIOS, G., ASSELBERGS, F.W., KAI, J. and WENG, S.F., 2021. Sex, age, and socioeconomic differences in non-fatal stroke incidence and subsequent major adverse outcomes. Stroke. 52(2), 396–405
• IYEN, B., WENG, S., VINOGRADOVA, Y., AKYEA, R.K., QURESHI, N. and KAI, J., 2021. Long-term body mass index changes in overweight and obese adults and the risk of heart failure, cardiovascular disease and mortality: a cohort study of over 260,000 adults in the UK BMC Public Health. 21(1), 576
• AKYEA, R.K., KONTOPANTELIS, E., KAI, J., WENG, S.F., PATEL, R.S., ASSELBERGS, F.W. and QURESHI, N., 2021. Sex disparity in subsequent outcomes in survivors of coronary heart disease Heart. Published Online First: 24 August 2021, heartjnl-2021-319566
• QURESHI, N., AKYEA, R.K., DUTTON, B., LEONARDI-BEE, J., HUMPHRIES, S.E., WENG, S. and KAI, J., 2021. Comparing the performance of the novel FAMCAT algorithms and established case-finding criteria for familial hypercholesterolaemia in primary care Open Heart. 8(2), e001752
• AKYEA, R.K., DOEHNER, W., IYEN, B., WENG, S.F., QURESHI, N. and NTAIOS, G., 2021. Obesity and long-term outcomes after incident stroke: a prospective population-based cohort study Journal of Cachexia, Sarcopenia and Muscle. Published Online First: 27 September 2021,
• IYEN, B., AKYEA, R.K., WENG, S., KAI, J. and QURESHI, N., 2021. Statin treatment and LDL-cholesterol treatment goal attainment among individuals with familial hypercholesterolaemia in primary care: Open Heart Open Heart. 8(2), e001817
• QURESHI, N., AKYEA, R.K., DUTTON, B., HUMPHRIES, S.E., ABDUL HAMID, H., CONDON, L., WENG, S.F. and KAI, J., 2021. Case-finding and genetic testing for familial hypercholesterolaemia in primary care. Heart. Published Online First: 14 September 2021,
• WENG, S.F., AKYEA, R.K., MAN, K.K.C., LAU, W.C. Y., IYEN, B., BLAIS, J.E., CHAN, E.W., SIU, C.W., QURESHI, N., WONG, I.C.K. and KAI, J., 2021. Determining propensity for sub-optimal low-density lipoprotein cholesterol response to statins and future risk of cardiovascular disease PLoS ONE. 16(12), e0260839
• AKYEA, R., QURESHI, N., DE LUSIGNAN, S., SHERLOCK, J., KAI, J., MCGEE, C. and WENG, S., 2020. Evaluating a clinical tool (FAMCAT) for identifying familial hypercholesterolaemia in primary care: a retrospective cohort study BJGP Open. Published Online: 17 November 2020, bjgpopen20X101114
• PERKINS, P., PARKINSON, A., AKYEA, R.K. and HUSBANDS, E., 2020. Nasal fentanyl alone plus buccal midazolam: an open-label, randomised, controlled feasibility study in the dying BMJ Supportive & Palliative Care. 10(3), 300-303
• AKYEA, R.K., LEONARDI-BEE, J., ASSELBERGS, F.W., PATEL, R.S., DURRINGTON, P., WIERZBICKI, A.S., IBIWOYE, O.H., KAI, J., QURESHI, N. and WENG, S.F., 2020. Predicting major adverse cardiovascular events for secondary prevention: Protocol for a systematic review and meta-analysis of risk prediction models BMJ Open. 10(7), e034564
• NTAIOS, G., WENG, S.F., PERLEPE, K., AKYEA, R., CONDON, L., LAMBROU, D., SIRIMARCO, G., STRAMBO, D., ESKANDARI, A., KARAGKIOZI, E., VEMMOU, A., KOROMPOKI, E., MANIOS, E., MAKARITSIS, K., VEMMOS, K. and MICHEL, P., 2020. Data-driven machine-learning analysis of potential embolic sources in embolic stroke of undetermined source European Journal of Neurology. First published online: 11 September 2020
• PERKINS, P., PARKINSON, A., PARKER, R., BLAKEN, A. and AKYEA, R.K., 2020. Does acupressure help reduce nausea and vomiting in palliative care patients? A double blind randomised controlled trial BMJ Supportive and Palliative Care. Published Online First: 8 October 2020
• AKYEA, R.K., QURESHI, N., KAI, J. and WENG, S.F., 2020. Performance and clinical utility of supervised machine-learning approaches in detecting familial hypercholesterolaemia in primary care npj Digital Medicine. 3(1), 142
• AKYEA, R., KAI, J., QURESHI, N., IYEN, B. and WENG, S.F., 2019. Sub-optimal cholesterol response to initiation of statins and future risk of cardiovascular disease. Heart. 105(13), 975-981
• PATEL, M., LEE, S.I., AKYEA, R.K., GRINDLAY, D., FRANCIS, N., LEVELL, N.J., SMART, P., KAI, J. and THOMAS, K.S., 2019. A systematic review showing the lack of diagnostic criteria and tools developed for lower limb cellulitis. British Journal of Dermatology. Accepted Manuscript Online: 7 March 2019,
• WENG, S.F., KAI, J., AKYEA, R. and QURESHI,N., 2019. Detection of familial hypercholesterolaemia: external validation of a clinical case-finding approach in a retrospective primary care cohort study. Lancet Public Health. 4(5), e256-e264
• AKYEA, R. K., MCKEEVER, T.M., GIBSON, J., SCULLION, J.E. and BOLTON, C.E., 2019. Predicting fracture risk in patients with chronic obstructive pulmonary disease: a UK-based population-based cohort study BMJ Open. 9(4), e024951
• AKYEA, R.A., KAI, J., QURESHI, N., HAMID, H.A. and WENG, S.F., 2019. Secondary Prevention of Cardiovascular Disease: Time to Rethink Stratification of Disease Severity? European Journal of Preventive Cardiology. Article first published online: 15 May 2019
• IYEN, B., QURESHI, N., KAI, J., AKYEA, R., LEONARDI-BEE, J., RODERICK, P., HUMPHRIES, S.E. and WENG, S., 2019. Risk of cardiovascular disease outcomes in primary care subjects with familial hypercholesterolaemia: a cohort study. Atherosclerosis. 287, 8-15
• AKYEA, R.K., KAI, J., QURESHI, N., IYEN, B. and WENG, S.F., 2019. LDL cholesterol response to statins and future risk of cardiovascular disease. Heart. 105(16), 1290-1291
• IYEN, B., QURESHI, N., KAI, J., AKYEA, R.K., LEONARDI-BEE, J., RODERICK, P., HUMPHRIES, S.E. and WENG, S., 2019. Risk Of Cardiovascular Disease Outcomes In Primary Care Subjects With Familial Hypercholesterolaemia: A Cohort Study Atherosclerosis Supplements. 38, e5
• BUSS, L., MCKEEVER, T. M., NIGHTINGALE, J., AKYEA, R., OLLIVERE, B., MOPPETT, I. K. and BOLTON, C. E., 2018. Hip fracture outcomes in patients with chronic obstructive pulmonary disease British Journal of Anaesthesia. 121(6), 1377-1379
• OFFOR UGONNA T., AKYEA RALPH K., NEEQUAYE JANET E., RENNER LORNA A. and SEGBEFIA CATHERINE I., The changing clinical pattern of endemic Burkitt lymphoma in Western Africa: Experience from a tertiary center in Ghana Pediatric Blood & Cancer. 0(0), e27275