School of Medicine
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Robert Wilcox

Emeritus Professor, Faculty of Medicine & Health Sciences


Expertise Summary

Clinical Trials concentrated primarily on pharmacological interventions in acute myocardial infarction and unstable angina with the aim of improving outcome, in terms of survival, symptoms and further resource need.

Research Summary

The Clinical Trials that I am currently involved in or for which I have DSMB or executive commoittee responsibilities are:

TRA 2P - a platelet thrombin receptor antagonist in acute coronary syndromes.

MRC - ILA - an interleukin 1 receptor antagonist in NSTEMI.

STREAM - pre-hospital thrombolysis versus primary PCI for STEMI.

TRILOGY - prasugrel versus clopidogrel in patients with acute coronary syndromes scheduled for medical therapy.

Recent Publications

  • AKERBLOM, J.S, CANNON, C, EMANUELSSON, G, ET AL (WILCOX, R.G and MEMBER OF THE DSMB), 2009. Comparison of ticagrelor, the first reversible oral P2Y12 receptor antagonist, with clopidogrel in patients with acute coronary syndrome: Rationale, design and baseline characteristics of the PLATelet inhibition and patient Outcome trial.: PLATO American Heart Journal. 157, 599-605
  • CARVER, A, RAFELT, S, GERSHLICK, A.H, FAIRBROTHER, K.L, HUGHES, S and WILCOX, R.G. FOR THE REACT INVESTIGATORS., 2009. Longer-Term Follow-Up of Patients Recruited to the REACT (Rescue Angioplasty Versus Conservative Treatment or Repeat Thrombolysis) Trial Journal of the American College of Cardiology. 54(2),
  • MEGA, J.L, BRAUNWALD, E, MOHANAVELU, S and ET AL (WILCOX, R.G. STEERING COMMITTEE AND UK LEAD INVESTIGATOR), 2009. Rivaroxaban versus placebo in patients with acute coronary syndromes (ATLAS ACS-TIMI 46): a randomised, double-blind, phase II trial. The Lancet. 374, 29-38
  • WALLENTIN, L., BECKER, R.C., BUDAJ, A., CANNON, C.P., ET AL (WILCOX, R.G and MEMBER OF THE DSMB), 2009. Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndrome: PLATO The New England Journal of Medicine. 361(11), 1045-1057

School of Medicine

University of Nottingham
Medical School
Nottingham, NG7 2UH

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