I obtained my Ph.D. in the filed of immunology and vaccinology from University of Malaya, Malaysia in 2006. After completing my Ph.D. I joined the Salmonella Live Vector Vaccine Unit at the Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, USA focusing on the development of attenuated bacterial live vector, Salmonella, as a carrier for vaccine delivery. Subsequently, I moved to another lab in Biology Department, John Hopkins University, Baltimore USA as a senior postdoctoral research fellow and worked on understanding the role of Interferon Regulatory Factors 5 (IRF5) in development and effector functions of B cells. Prior to join the University of Nottingham Malaysia Campus in 2014, I worked as lecturer for several years in local institutions mainly involved in teaching Immunology and Microbiology modules for medical, pharmacy and life sciences students.
Module convener: Therapeutic Immunology (LIFE4130); Sexual Health and Pregnancy (PHAR2020); Professional Competencies 2 (PHAR2022)
Involved in the teaching of : Being a Pharmacist (PHAR1009), Human Physiology (LIFE1052), Fundamentals of Neuroscience (LIFE1051); Concepts of Pharmacogenetics (LIFE3052); Pharmacological Basis of Therapeutics (LIFE2088); Asthma, Allergy and Immune disease (PHAR2017); Renal and Endocrine Diseases (PHAR2019); Neurobiology of Disease (LIFE2089)
Supervision: Final Year Projects, Postgraduate research studies
My research primarily focuses on understanding the role of Interferon and Interferon Regulatory Factors (IRFs) in development of lymphoid cells, allergy, autoimmune diseases and carcinogenesis. My… read more
SONIA HOW MING WONG, CHEE MUN FANG, LAY-HONG CHUAH, CHEE ONN LEONG and SIEW CHING NGAI, 2018. E-cadherin: Its dysregulation in carcinogenesis and clinical implications. Critical Reviews in Oncology/Hematology. 121, 11-22. KAUR A, LEE LH, CHOW SC and FANG CM, 2018. IRF5-mediated immune responses and its implications in immunological disorders. International reviews of immunology. 37(5), 229-248 LE CF, KAILAIVASAN TH, CHOW SC, ABDULLAH Z, LING SK and FANG CM, 2017. Phytosterols isolated from Clinacanthus nutans induce immunosuppressive activity in murine cells. International immunopharmacology. 44, 203-210
LE CF, FANG CM and SEKARAN SD, 2017. Beyond membrane-lytic: Intracellular Targeting Mechanisms by Antimicrobial Peptides. Antimicrobial agents and chemotherapy.
My research primarily focuses on understanding the role of Interferon and Interferon Regulatory Factors (IRFs) in development of lymphoid cells, allergy, autoimmune diseases and carcinogenesis. My current works include vaccine development against various infectious diseases by using Salmonella as a carrier for vaccine delivery as well as characterization of immunomodulatory properties of bioactive fraction from plant materials.