I am a Pharmacist, (Dipl Eng) and obtained my degree from the Faculty of Pharmacy and Biochemistry, University of Zagreb, Croatia, where I was also awarded a master in pharmaceutical technology degree, after spending a research visit time at the Department of Pharmacology and Therapeutics at McGill University, Canada. I was awarded a PhD (Doctoral) degree by Faculty of Pharmacy and Biochemistry, University of Zagreb, Croatia for research completed at School of Pharmacy, University of Nottingham under supervision of Profs SS Davis and L Illum. I was appointed AstraCharnwod lecturer in Drug Delivery at the School of Pharmacy, Nottingham and to Lecturer in Advanced Drug Delivery in 2000. In 2006 I was promoted to Associate Professor in Advanced Drug Delivery.
My research lies at the interface between physicochemical characterisation and biological properties of drug delivery systems. Representative examples include defining the relationship of surface… read more
ALEJANDRO NIETO-ORELLANA, MARCO DI ANTONIO, CLAUDIA CONTE, FRANCO H FALCONE, CYNTHIA BOSQUILLON, NICK CHILDERHOUSE, GIUSEPPE MANOTVANI and SNOW STOLNIK, 2017. Effect of polymer topology on non-covalent
polymer–protein complexation: miktoarm versus
linear mPEG-poly(glutamic acid) copolymers Polymer Chemistry. 8, 2210-2220 CAPEL V, VLLASALIU D, WATTS P and STOLNIK S, 2016. Insight into the relationship between the cell culture model, cell trafficking and siRNA silencing efficiency. Biochemical and biophysical research communications. 477(2), 260-5
NAIM HAGE, TINA HOWARD, CHRIS PHILLIPS, CLAIRE BRASSINGTON, ROSS OVERMAN, JUDIT DEBRECZENI, PAUL GELLERT, SNOW STOLNIK, G SEBASTIAAN WINKLER and F FALCONE, 2015. Structural basis of Lewisb antigen binding by the Helicobacter pylori adhesin BabA Science Advances. 1(e1500315),
My research lies at the interface between physicochemical characterisation and biological properties of drug delivery systems. Representative examples include defining the relationship of surface coverage vs biological fate in pegylated nano-carriers for drug targeting (e.g. Stolnik S et al, Biochim. Biophys. Acta- Biomembr. 1514, 2001, 261), the use of novel polymeric materials in surface engineering of gene delivery constructs (e.g. Lam J et al, Journal of Controlled Release, 100, 2004, 293) and specially tailored functionalized polymers for enhanced drug incorporation into self assembled carriers (Prompruk K et al, International Journal of Pharmaceutics, 296, 2005, 242). Recently, I have applied principles of polyelectrolyte assembly to the formation of nano-sized drug delivery systems and polymeric constructs, and to the construction of coatings on the cell surface.
I have been, and currently have, a close collaboration with LBSA at the School in development and characterization of novel drug delivery systems (Prof MC Davies and C Roberts) while the collaborations with research groups at the Nottingham University include those with Dr C Hayes (Chemistry), Prof M Somekh (Electrical Enginering) Dr D Gray (Biochemical Sciences). Collaborations with other expert groups in synthetic and colloid chemistry include research on applications of new polymers in drug delivery with Prof SP Armes (Chemistry Scheffield).
I have a number of industrially funded projects from collaborations with pharmaceutical and biotechnology companies including Biocompatibles, Phaeton, NittoDenko (Japan), UCB-Celltech, Critical Pharmaceutics and AstraZeneca.
I currently have The Royal Society Industrial Fellowship position - for the transfer of drug delivery technologies from academic to industrial environment (2005-2007).
Membership of Committees and Professional Bodies:Currently: SCI and RSC joint Colloid and Surface Chemistry Committee member (organized Colloids in the Body 2007 meeting)Eminate (Nottingham) Science CommitteeJournal of Biomedical Nanotechnology editorial board (American Scientific Publishers)