I am currently working as Beacon Anne McLaren Research Fellow at the University of Nottingham.
I obtained my PhD from Korea University, South Korea under the supervision of Prof. Stephen Jackson. And then I worked as a post-doctoral research associate with Prof Matt Lambon Ralph at Neuroscience and Aphasia Research Unit (NARU) in the University of Manchester.
Semantic cognition refers to our ability to use, manipulate and generalize knowledge and is a crucial function for our communication (verbal and nonverbal) and activities of daily living (e.g.,… read more
JUNG J, WILLIAMS SR, SANAEI NEZHAD F and LAMBON RALPH MA, 2017. GABA concentrations in the anterior temporal lobe predict human semantic processing. Scientific reports. 7(1), 15748
Semantic cognition refers to our ability to use, manipulate and generalize knowledge and is a crucial function for our communication (verbal and nonverbal) and activities of daily living (e.g., object use). Although advances in neuroscience techniques have allowed important progress in understanding where and how brain systems code meaning at the cortical level, there is still a lack of any neurobiological explanation for semantic processing. GABA and glutamate, as major neurotransmitters in brain, play a major role in shaping cognitive functions whilst the complex interplay between them generates the neuroplasticity that enables the brain to adjust its performance. Therefore, one of the key issues in cognitive neuroscience is to link the underlying neurochemical mechanisms to our flexible cognitive behaviours, which has critical implications for clinical interventions (e.g., pharmacological treatments).
My goal is to reveal the neurochemical mechanisms of human semantic cognition by establishing combinations of neuroscientific methods. To provide convergent understanding of this, I combine brain stimulation techniques with advanced neuroimaging approaches, including:
- Transcranial magnetic stimulation/transcranial direct current stimulation (TMS/tDCS)
- Structural and functional neuroimaging (DTI/DWI and resting-state/task-related fMRI)
- Magnetic resonance spectroscopy (MRS)
I am also interested in the ways in which semantic cognition interacts with other domain-general higher cognitive functions (e.g., default mode network and executive control system). To explore this complex interplay between these systems, I use advanced neuroimaging analyses such as independent component analysis, dynamic causal modelling, representational similarity analysis, and graph-theory network analysis.