Centre of Evidence Based Dermatology
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Barrier Enhancement for Eczema Prevention (The BEEP Study)


The BEEP study is looking at preventing eczema in newborn babies

The BEEP study aims to find out whether skin care advice including applying emollients can prevent eczema in newborn babies compared with skin care advice alone.

Update: 1395 families are taking part in the study and we expect to have the results available by early 2019 after all the children in the study have reached two years of age. 

Many thanks to all families who are taking part and any who expressed an interest but were unable to participate. Please do contact us if you are not taking part but would like to receive a copy of the results.


BEEP logo

For those involved in the study, please do keep completing the questionnaires. These are really important for the results of the study.

Data from the BEEP trial will be incorporated into a prospective, individual patient data meta-analysis led by members of the BEEP team, of similar ongoing barrier studies which will allow more power to look at some of the secondary outcomes as well as a timely and high-quality meta-analysis of the primary outcome. Other related trials will be incorporated into a retrospective systematic review.

Key facts

1. Why are we doing this study?

Having eczema can have a big impact on people’s lives and because there is no cure, we would like to find a way to prevent eczema developing in children. We don’t know whether adding in emollients to the skin care advice given to parents is effective in preventing eczema, and the only way to find out is by doing this study.

The BEEP study was discussed in a BBC East Midlands Today feature on eczema. The BBC have kindly allowed us to share this:



2. How many families are involved in the BEEP study?

1395 families with newborn babies who have asthma, eczema or hayfever in the immediate family are taking part in this study.


3. Who was eligible to take part?

Families who were expecting a baby, and had at least one person in their immediate family with eczema, asthma or hayfever (now or in the past).

Please note, recruitment to the study has now closed.

4. How long will the study last for?

Recruitment to the study has now closed. Results are expected in early 2019.


5. What is involved in taking part?

Each family will take part in the study for up to 5 years. The study nurse will carry out a skin assessment when your child is around 2 years of age and this can either be at your home or the hospital, whichever you prefer. We will also ask each family to fill in some short questionnaires approximately once or twice a year until your child’s fifth birthday. Although this may seem like a long time, it is important that we look at the long term effectiveness to answer the question properly. 



6. Where is the study taking place?  

The BEEP study is taking place in the following areas:

  • Nottingham
  • London
  • Sheffield
  • Derby
  • Leicester
  • Portsmouth
  • Harrogate
  • Burton
  • York
  • Mansfield
  • Bristol

7. Who is funding the study?

This study is funded by the Department of Health. It is led by Professor Hywel Williams at the Centre of Evidence Based Dermatology, The University of Nottingham, and coordinated by The Nottingham Clinical Trials Unit.



How-to guide for saliva sample collection.



Funding Acknowledgement

This project is funded by the National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme (project number 12/67/12).

Department of Health Disclaimer

The views and opinions expressed therein are those of the authors and do not necessarily reflect those of the Health Technology Assessment programme, NIHR, NHS or the Department of Health.


Centre of Evidence Based Dermatology

The University of Nottingham
King's Meadow Campus
Lenton Lane
Nottingham, NG7 2NR

telephone: +44 (0) 115 823 1048