Centre of Evidence Based Dermatology

Eczema research

Eczema is a common condition yet there are numerous uncertainties in its treatment.

Research overview

Eczema (also known as atopic eczema or atopic dermatitis) is one of our key areas of research interest, and we are one of the leading eczema research groups in the world.

We design and conduct clinical studies that address questions raised by doctors and patients, to ensure that our research has a direct impact on clinical practice.

Our research was highly rated in the Research assessment Framework (REF2014) exercise.

Details of all our research projects are listed on this page.

Ongoing projects

Rapid eczema trials  (Programme Grant) Working with members of the public to prioritise, design and conduct high-quality online trials to test different ways of managing eczema. Currently recruiting patients for the Eczema Bathing Study

HOME initiative Developing a consensus based outcome measure set for eczema (Membership open)


Outcomes & diagnostics

UK Diagnostic criteria for Atopic Dermatitis - A manual for researchers identifying people with eczema.

Patient Oriented Eczema Measure (POEM) -A patient-reported outcome measure for monitoring atopic eczema severity.

Nottingham Eczema Severity Score (NESS) - An eczema severity measure based on the Rajka and Langeland grading.

Eczema Flares - A collection of information on how flares could be captured in clinical trials.



Psychology and Eczema: The use of stories - Stories about eczema that can be easily personalised for children.

Map of systematic reviews on atopic eczema - Comprehensive categorized list of systematic reviews published on eczema. Updated monthly.

GREAT Database - A database of randomised controlled trials of eczema treatments published from 2000 onward.


All projects

Rapid Eczema Trials A project working with members of the public to prioritise, design and conduct high-quality online trials to test different ways of managing eczema. NIHR Recruiting
EMO Study EMO is a research study looking at how eczema changes over time and how people manage their eczema remotely. The study is being carried out entirely online.   Complete
Eczema Care Online  Looking at online interventions to support people with eczema. NIHR Complete Visit the final website
The Dragon in my Skin An artistic outreach project designed to communicate 5 key messages about eczema self-care, and to raise awareness about the condition to the wider community. NIHR Complete
Best Emollient for Eczema (BEE) study A study trying to improve childhood eczema treatment by providing information about which emollients are most acceptable and effective NIHR Complete
Understanding the long-term management of eczema A project to establish what measurements should be captured when assessing the long-term managment of eczema British Skin Foundation Complete
Paper 1
Paper 2
Barrier Enhancement for Eczema Prevention (BEEP) study A study which aims to find out whether applying emollients to newborn babies can prevent the development of eczema.  NIHR HTA 11/67/62 Complete year 2 results published
Bath Additives for the Treatment of Childhood Eczema (BATHE) study A study which will assess whether bath emollients help children with eczema. NIHR HTA 11/153/01 Published
Clothing for the relief of Eczema Symptoms (CLOTHES) study A study designed to evaluate the role of specialist clothing eczema management. NIHR HTA 11/65/01 Published
Harmonizing Outcome Measures for Eczema (HOME) initiative An international initiative working to establish core outcome measures for eczema trials.  None Ongoing
Systematic review of treatments for eczema A project that updated the previous HTA review of eczema treatment RCTs, covering 2000-2013 NIHR PGfAR - RP-PG-0407-10177 Published
Softened Water Eczema Trial (SWET) study
A study that evaluated whether using an ion-exchange water softener could help reduce eczema severity NIHR HTA 05/16/01 Published
Validation of an objective measure of scratch in patients with eczema A study that assessed the usefulness of using scratch accelerometers to record night - time scratching in children with eczema. Queen's Medical Centre University Hospital NHS Trust Published
Barrier Enhancement for Eczema Prevention: The BEEP feasibility study A project that looked at the feasibility of performing a study on preventing the development of eczema. NIHR PGfAR - RP-PG-0407-10177 Complete
The prevention of eczema in infants and children: An overview of Cochrane and non-Cochrane reviews A project that summarised reviews on eczema prevention NIHR PGfAR - RP-PG-0407-10177 Published
Eczema Priority Setting Partnership A project that identified and prioritised uncertainties about treatments for eczema. NIHR PGfAR - RP-PG-0407-10177 Published
A prospective observational study of environmental factors affecting atopic eczema in children A study/project that explored what  environmental factors causes eczema  to  flare. BUPA Foundation and Bastow Research grant from the Special Trustees for Nottingham University Hospitals Published;
Feasibility study for a randomised controlled trial of water softeners in the treatment of atopic eczema A pilot study that evaluated whether using an ion-exchange water softener could help reduce eczema severity Kinetico UK Ltd Published
Short bursts of a potent topical corticosteroid vs prolonged use of a mild topical corticosteroid A study that assessed whether a short burst of a potent topical corticosteroid is  as effective as prolonged use of a milder steroid for controlling mild or moderate eczema in children. NHS Research and Development Programme (Trent) Published
Do nurse follow-up clinics help patients and do they free up consultants' time?  A study which assessed the impact of providing a nurse follow-up clinic in addition to the normal service  Crookes Healthcare Published
International Study of Asthma and Allergies in Childhood A worldwide epidemiological research programme established in 1991 to investigate asthma, rhinitis and eczema in children  None Published

Centre of Evidence Based Dermatology

The University of Nottingham
Applied Health Research Building
University Park, Nottingham

telephone: +44 (0) 115 84 68631
email: cebd@nottingham.ac.uk