Medicine Safety and Effective Healthcare Research

Work package 1

Measuring serious harm, and economic impact, associated with hazardous prescribing

Objectives

  • Determine the risk of serious harm, and economic impact, associated with hazardous prescribing
  • Validate the algorithms that will be used to identify the serious harm outcomes in WP2 and WP3
  • Develop a composite measure for the serious harm outcomes
  • Develop the economic models that will be used to evaluate the cost-effectiveness of the interventions in WP2 and WP3

Methods

We will examine existing large population-based observational studies, and undertake one new GP-database cohort study

Outcomes

  • The absolute attributable risk of serious harm associated with 11 specific types of hazardous prescribing
  • Markov models to estimate the effect of hazardous prescribing on Quality-Adjusted-Life-Years (QALYs)

WP1 team members

  • Professor Darren Ashcroft (lead)
  • Professor Tony Avery
  • Professor Rachel Elliott
  • Professor Bruce Guthrie
  • Dr Pearl Mok
  • Dr Daniel Morales
  • Professor Tjeerd van Staa

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Medicine Safefy and Effective Healthcare Research

The University of Nottingham
School of Medicine


telephone: +44 (0) 115 823 0209
email:anthony.avery@nottingham.ac.uk