The importance of the health of mothers and their infants begins before conception, is critical throughout pregnancy and beyond. Our research is improving understanding of the mechanisms which underlie sub-optimal maternal and fetal health, detection of difficulties and evidence-based treatments to improve health.
1. Fertilisation and the pre-implantation embryo
Dr Walid Maalouf is leading a number of research projects focusing on the effects of different micromanipulation techniques which are commonly used in ART treatment, on fertilisation and on the further development of the mammalian embryo. A special interest of his research group is the impact of new technology in the ART laboratory on the improvement and safety of clinical treatment and animal research. In collaboration with Dr Nathalie Beaujean at INRA, France, this research group has published a number of articles on the organisation of the embryonic genome after nuclear transfer (aka cloning), and continues to do so. Also, in collaboration with Hamilton Thorne Biosciences, MA, USA, they have been able to assess novel applications of their laser technology during intra-cytoplasmic sperm injection (ICSI) and trophectoderm biopsy.
2. Reproductive Imaging
3. Perinatal trials
Using the very latest wide-bore MRI scanning equipment at the University of Nottingham experts in the School of Physics and Astronomy together with Nottingham University Hospitals NHS Trust are leading a study to understand how the placenta ensures the right amount of oxygen and nutrients reach the baby in the womb.
We have supported the creation of University spinout companies in gynaecology - N.G.D. Limited, Nottingham Gynaecological Devices and Nurture Fertility.
Nurture Fertility provides a high quality clinical service in assisted reproduction techniques and a teaching and research base in this area, under the direction of Mr. James Hopkisson (NHS) and Associate Professor Dr Nick Raine-Fenning (UoN).
Our research is published in leading peer-reviewed journals. See the individual publication records of our members for details.