Tobacco and Alcohol Research


The SNAP 2 trial is looking to test enhanced support to help pregnant women use Nicotine Replacement Therapy (NRT) as part of a quit attempt. 


The SNAP 2 trial aims to test whether a new support package called 'Baby, Me & NRT', can help pregnant women to use enough Nicotine Replacement Therapy (NRT). In the UK, NRT products are available free of charge during pregnancy, but may women do not use them in sufficient doses or for long enough to get the best results.


A multi-centre, randomised control trial of the Baby, Me & NRT support package plus usual stop smoking support vs. usual stop smoking support alone. 

Pregnant women will be recruited from different hospitals (and on-line) over 9 months. Those who want to take part in the trial will be randomly placed by a computer into one of two groups. Group 1 will receive usual support to stop smoking and Group 2 will receive usual support to stop smoking plus the Baby, Me & NRT support package. The aim is to recruit 264 participants (132 in the Baby, Me & NRT group / 132 in the usual support group).

All participants will be offered NRT and six telephone or video consultations with a stop smoking practitioner. Those in Baby, Me & NRT group will receive additional support and resources. Research data will be collected using a mobile phone app and online surveys, along with saliva samples at various timepoints. 








Tobacco and Alcohol research

The University of Nottingham

email:Chris Hill