I received my PhD in behavioural neuroscience from McGill University, Canada in 2004. That year I also received a Marie Curie Fellowship from the EU to conduct post-doctoral research in the School of Biomedical Sciences here at the University of Nottingham. In 2006 I received a Young Investigator from NARSAD to continue this work. After a short spell at De Montfort University I returned to the University of Nottingham in 2008 to take up a Lectureship in Neuroscience at Sutton Bonington Campus in the School of Biosciences.
I have extensive experience with rodent behavioural testing, stereotaxic surgery, systemic and central drug infusion, in vivo voltammetry, in vivo electrophysiology and ex vivo neurochemical quantification methods.
I supervise final year undergraduate dissertations and I teach on various undergraduate modules in the School of Biosciences: Coordinated Physiological Functions (module convenor), Animal Biology… read more
Our group is investigating (1) the neurochemical and neural circuit basis of fear memory processing, and (2) early environmental programming of neuroendocrine and cognitive function. We conduct this… read more
Local Group Representative for the British Neuroscience Association
Editorial Board Member for Neuroscience Journal and OA Neurosciences
Ad hoc reviewer for various journals and funding bodies in the UK and Europe
I supervise final year undergraduate dissertations and I teach on various undergraduate modules in the School of Biosciences: Coordinated Physiological Functions (module convenor), Animal Biology (module convenor), Introductory Physiology, Physiology of Electrically Excitable Tissues, and Systems Neurophysiology.
Our group is investigating (1) the neurochemical and neural circuit basis of fear memory processing, and (2) early environmental programming of neuroendocrine and cognitive function. We conduct this research in collaboration with various local, national and international partners:
Sex differences in learned fear inhibition and associated neural circuitry, with Dr Mason (Life Sciences), Dr Halliday (University of York), and Dr Bredy (University of California at Irvine, US)
Computational modeling of neural circuit function underlying fear memory processing, with Dr Mason (Life Sciences), Prof Coombes, Prof Owen, and Dr O'Dea (all Mathematical Sciences)
Role of dopamine in fear memory encoding, with Dr Bast, Dr Pezze (both Psychology), Dr Voigt (Veterinary Medicine & Science), Dr Lee (University of Birmingham)
Role of cannabidiol in regulating learned fear extinction and associated neural circuitry, with Dr Lee (University of Birmingham), Prof Guimaraes, Dr Resstel, and Dr Joca (all University of Sao Paulo, Brazil)
Impact of early life stress on later stress axis regulation and cognition in sheep, with Prof Sinclair (Biosciences), Dr Rutherford, and Prof Dwyer (both Scotland's Rural College (SRUC), Edinburgh)
My doctoral research investigated central dopamine system interactions in brain regions involved in cognition and emotion. Dopamine plays an important role in various aspects of behaviour and altered dopamine transmission is involved in the pathophysiology of psychiatric disease. I examined the relationship between dopamine neurotransmission in different brain areas in response to stress and during various types of cognitive processing.
My post-doctoral research investigated the 'programming' of later cognition, emotion and brain function by the early rearing environment. Early adversity increases the risk of developing psychiatric disease later in life. Early life is a crucial time for nervous system development and insults during this critical period can permanently alter brain function and behaviour. I examined the effects of early life stress on later emotional memory processing and brain function in areas involved in cognition and emotion.