School of Biosciences
  • Print
   
   
 

Image of Sandy Hwei San Loh

Sandy Hwei San Loh

Professor and Director of Biotechnology Research Centre, Faculty of Science

Contact

  • workRoom B1A22 Block B1
    Malaysia Campus
    Jalan Broga
    43500 Semenyih
    Selangor Darul Ehsan
    Malaysia
  • work+6 (03) 8924 8215
  • fax+6 (03) 8924 8018

Biography

Dr Sandy Loh, a virologist and molecular biologist, graduated her bachelor's and PhD's degrees from Universiti Putra Malaysia (UPM). After her PhD graduation, she worked as a post-doctoral research fellow in the Institute of Bioscience, UPM for one year, then, she joined the University of Nottingham Malaysia Campus (UNMC) in 2006 and has been working until present. She is now a Professor of the university, a Fellow of the Higher Education Academy, UK and has been lecturing in the molecular biology and biotechnology areas for ten years. Since October 2010, she has been appointed as the UNMC Director of Biotechnology Research Centre which facilitates different areas of molecular biotechnology and plant tissue culture researches. She is the founding leader of Molecular Pharming and Bioproduction (MPharmBio) Research Group at UNMC. Her current research interests include the application of molecular pharming approach in developing safer and more cost-effective plant-based vaccine candidates for controlling human and poultry viral diseases as well as plant-made biopharmaceutical proteins for treating cancers and for health promotion; investigations on medicinal plant metabolites and pure bioactives from tropical plant species aiming for new therapeutics discovery; combinatorial application of vitamin E isomers and nanomedicine as an alternative cancer treatment strategy. She had received a few awards in recognition of her excellent research and teaching achievements such as Pfizer's Prize, Bronze and Silver Medals from UPM, New Researcher Award from Nottingham University, MAKNA Award from Malaysian National Cancer Council, ITEX MIPA Gold Medal, UNMC Staff Oscar and WinSET Career Achievement Award.

Teaching Summary

I had completed the PGCHE programme and awarded as a Fellow of the Higher Education Academy, UK. My teaching interests cover mainly in molecular biology and its related areas. I have been… read more

Research Summary

I am the founding leader of the "Molecular Pharming and Bioproduction (MPharmBio) Research Group and "Plant Vaccine Research Unit" at UNMC. My research interests cover (i) molecular pharming in the… read more

Selected Publications

I had completed the PGCHE programme and awarded as a Fellow of the Higher Education Academy, UK. My teaching interests cover mainly in molecular biology and its related areas. I have been coordinating and teaching "Genes and Cells: 1 and 2", "Molecular Biology and the Dynamic Cell" and "Molecular Pharming and Biotechnology" modules under the BSc Plant Biotechnology and Biotechnology programmes. I have also been contributing teaching in "Plant Biotechnology", "Introductory Plant Pathology", and "Molecular Plant Pathology" under the BSc Plant Biotechnology and Biotechnology programmes and "Plant Genetic Manipulation Practical Techniques" module under the MSc Crop Biotechnology programme. I have almost 10 years of experience in supervising more than 18 PhD students in my areas of expertise.

Current Research

I am the founding leader of the "Molecular Pharming and Bioproduction (MPharmBio) Research Group and "Plant Vaccine Research Unit" at UNMC. My research interests cover (i) molecular pharming in the area of vaccine development for poultry diseases as control strategies using plant systems; (ii) development of plant-made biopharmaceutical proteins in plants using emerging agroinfiltration platform (iii) natural product in the aspect of biological investigations particularly on antiviral, antibacterial and anticancer properties; and (iv) development of nanosensor for pathogens detection. These research activities have been funded by different ranges of grants especially in my capacity as a project leader/principle investigator from MOSTI, MOA, MoHE, MAKNA, NRF, AAR and Davos. Interdisciplinary research collaborations have been established in these areas with different schools in UNMC; Sutton Bonington and University Park campuses; local and international research institutes and universities as well as private commercial companies.

  • LEONG, Y.K., LAN, J.C.-W., LOH, H.-S., LING, T.C., OOI, C.W. and SHOW, P.L., 2017. Cloud-point extraction of green-polymers from Cupriavidus necator lysate using thermoseparating-based aqueous two-phase extraction. Journal of Bioscience and Bioengineering. 123(3), 370-375
  • PUA, T.L., CHAN, X.Y., LOH, H.-S., OMAR, A.R., YUSIBOV, V., MUSIYCHUK, K., HALL, A.C., COFFIN, M.V., SHOJI, Y., CHICHESTER, J.A., BI, H. and STREATFIELD, S.J., 2017. Purification and immunogenicity of hemagglutinin from highly pathogenic avian influenza virus H5N1 expressed in Nicotiana benthamiana. Human Vaccines & Immunotherapeutics. 13(2), 1-8
  • PANG, E.L. and LOH, H.-S., 2017. Towards development of a universal dengue vaccine – how close are we? Asian Pacific Journal of Tropical Medicine. 10(3), 220-228
  • ABUBAKAR, I.B., LIM, K.-H., KAM, T.-S. and LOH, H.-S., 2017. Enhancement of apoptotic activities on brain cancer cells via the combination of γ-tocotrienol and jerantinine A. Phytomedicine. 30, 74-84
  • LOW, S.S., LOH, H.-S., BOEY, J.S., KHIEW, P.S., CHIU, W.S. and TAN, M.T.T., 2017. Sensitivity enhancement of graphene/zinc oxide nanocomposite-based electrochemical impedance genosensor for single stranded RNA detection. Biosensors and Bioelectronics. 94, 365-373
  • LIM, S.S., CHAI, C.Y. and LOH,H-S, 2017. In vitro evaluation of osteoblast adhesion, proliferation and differentiation on chitosan-TiO2 nanotubes scaffolds with Ca2+ ions. Materials Science and Engineering: C. 76, 144–152
  • PANG E.L., PEYRET, H., LOMONOSSOFF, G.P., PONG, L.-Y., SHARIFAH, S.H., FANG, C.-M., LAI, K.-S. and LOH, H.-S., 2017. Evaluation of immunogenicity of a recombinant plant-derived dengue vaccine candidate in BALB/c Mice. In: Plant-Based Vaccines, Antibodies and Biologics (PBVAB) 2017. Albufeira, Portugal.
  • CHAN, X.-Y., MUSIYCHUK, K., SHOJI, Y., YUSIBOV, V., MOHD LILA, M.A. and LOH, H.-S., 2017. Production of recombinant apoptin in planta and preliminary evaluation of plant-made apoptin on human lung adenocarcinoma cells. In: Plant-Based Vaccines, Antibodies and Biologics (PBVAB) 2017. Albufeira, Portugal.
  • THAM, S.Y., MAI, C.W., FU, J.Y. and LOH, H.-S., 2017. Beyond the magic bullet: Multitargeted novel drugs cocktails. In: UNMC Research Showcase 2017. Selangor, Malaysia.
  • LOH, H.-S., GREEN, B.J. and YUSIBOV, V., 2017. Using transgenic plants and modified plant viruses for the development of treatments for human diseases. Current Opinion in Virology. 26, 81-89
  • LEONG, Y.K., SHOW, P.L., LAN, J.C.-W., LOH, H.-S., YAP, Y.J. and LING, T.C., 2017. Extraction and purification of Polyhydroxyalkanoates (PHAs): application of Thermoseparating aqueous two-phase extraction. Journal of Polymer Research. 24(10), 158
  • ABUBAKAR, I.B., LIM, S.-W. and LOH, H.-S., 2017. Synergistic apoptotic effects of tocotrienol isomers and Acalypha wilkesiana on A549 and U87MG cancer cells. Tropical Life Sciences Research.
  • LOH, H.-S., PUA, T.-L., MUSIYCHUK, K., SHOJI, Y., CHICHESTER, J. and YUSIBOV, V., 2017. Production of avian influenza H5N1 vaccine candidate using a modified plant virus-based transient expression strategy (Invited Talk). In: The 42nd Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology (MSBMB). Kuala Lumpur, Malaysia.
  • LEONG, Y.K., LAN, J.C.-W., LOH, H.-S., LING, T.C., OOI, C.W. and SHOW, P.L., 2016. Thermoseparating aqueous two-phase systems: Recent trends and mechanisms. Journal of Separation Science. 39(4), 640-647
  • LOW, S.S., TAN, M.T.T., KHIEW, P.S., LOH, H.-S. and CHIU, W.S., 2016. One step green preparation of graphene/ZnO nanocomposite for electrochemical sensing. Journal of Nanoscience and Nanotechnology. 16(7), 7420-7426
  • LOW, S.S., TAN, M.T.T., LOH, H.-S., KHIEW, P.S. and CHIU, W.S., 2016. Facile hydrothermal growth graphene/ZnO nanocomposite for development of enhanced biosensor. Analytica Chimica Acta. 903, 131-141
  • YAP, V.A., QAZZAZ, M.E., RAJA, V.J., BRADSHAW, T.D., LOH, H.-S., SIM, K.-S., YONG, K.-T., LOW, Y.-Y. and LIM, K.-H., 2016. Fistulopsines A and B antiproliferative septicine-type alkaloids from Ficus fistulosa. Phytochemistry Letters. 15, 136-141
  • PANG, E.L. and LOH, H.-S., 2016. Current perspectives on dengue episode in Malaysia. Asian Pacific Journal of Tropical Medicine. 9(4), 395–401
  • ABUBAKAR, I.B. and LOH, H.-S., 2016. A review on ethnobotany, pharmacology and phytochemistry of Tabernaemontana corymbosa. Journal of Pharmacy and Pharmacology. 68(4), 423–432
  • ABUBAKAR, I.B., LIM, K.-H., KAM, T.-S. and LOH, H.-S., 2016. Synergistic cytotoxic effects of combined δ-tocotrienol and jerantinine B on human brain and colon cancers. Journal of Ethnopharmacology. 184, 107–118
  • LOW, S.S., CHIA, J.S.Y., TAN, M.T.T., LOH, H.-S., KHIEW, P.S., SINGH, A. and CHIU, W.S., 2016. A proof of concept: Detection of avian influenza H5 gene by a graphene-enhanced electrochemical genosensor. Journal of Nanoscience and Nanotechnology. 16(3), 2438-2446
  • NG, C.M., LOH, H.-S., MUTHOOSAMY, K., SRIDEWI, N. and MANICKAM, S., 2016. Conjugation of insulin onto the sidewalls of single-walled carbon nanotubes (SWCNTs) through functionalization and diimide-activated amidation. International Journal of Nanomedicine. 2016:11, 1607-1614
  • LOH, H.-S., 2016. Molecular pharming: Plant-based production of recombinant biopharmaceutical proteins (Inaugural Lecture). In: International Conference on Frontiers in Life Science (ICFLS’16). Tiruchirappalli, India.
  • PANG, E.L., PEYRET, H., RAMIREZ, A., WHELAN, M., LOMONOSSOFF, G.P., LAI, K.S. and LOH, H.-S., 2016. Epitope presentation of consensus dengue viral envelope glycoprotein domain III on plant-derived virus-like particles. In: New Technologies, New Vaccines 2016 (NTNV 2016). Wilmington, USA.
  • MALIK F.Z.A., ZEENATHUL, N.A., LOH, H.S., TING, K.N., HANI, H. and ABDULLAH, R., 2016. Antiviral and virucidal activities of Duabanga grandiflora leaf extract against Pseudorabies virus in vitro. BMC Complementary and Alternative Medicine. 16, 139
  • CHAN, X.Y., LOH, H.-S., MUSIYCHUK, K., SHOJI, Y., MOHD LILA, M.A. and YUSIBOV, V., 2016. The expression of apoptin (viral protein 3) in Nicotiana benthamiana and its bioactivity in human cancer cells. In: New Technologies, New Vaccines 2016 (NTNV 2016). Wilmington, USA.
  • LOH, H.-S., 2016. Plants as green biofactories for therapeutics and vaccines (Plenary Lecture). In: UTAR Intervarsity Scientific Symposium (UISS 2016). Perak, Malaysia.
  • ABUBAKAR, I.B., LIM, K.-H. and LOH, H.-S., 2016. Synergistic apoptotic effects of combined low-dose γ-Tocotrienol and Jerantinine A treatments on cancer cells. In: International Conference of Translational Molecular Imaging & Aeorospace Medicine & Physiology (iCT-MIPs 2016). Sepang, Malaysia.
  • THAM, S.Y., FU, J.Y., MAI, C.W. and LOH, H.-S., 2016. High-throughput screening of prospective combinations of tocotrienols and chemotherapeutic drugs on cancer cells. In: International Conference of Translational Molecular Imaging & Aeorospace Medicine & Physiology (iCT-MIPs 2016). Sepang, Malaysia.
  • MUTHOOSAMY, K., ABUBAKAR, I.B., BAI, R.G., LOH, H.-S. and MANICKAM, S., 2016. Exceedingly higher co-loading of curcumin and paclitaxel onto polymer-functionalized reduced graphene oxide for highly potent synergistic anticancer treatment. Scientific Reports. 6, 32808
  • LEONG, Y.K., SHOW, P.L., LIN, H.C., CHANG, C.K., LOH, H.-S., LAN, J.C.-W. and LING, T.C., 2016. Preliminary integrated economic and environmental analysis of polyhydroxyalkanoates (PHAs) biosynthesis. Bioresources and Bioprocessing. 3, 41
  • LOH, H.S., THAM, S.Y., ABUBAKAR, I.B., FU, J.Y., MAI, C.W. and LIM, K.H., 2016. Enrichment of cancer therapeutic benefits by a prospective combination of tocotrienols and chemotherapeutic candidates (Invited Talk). In: Pharma + Bio Asia 2016 Conference. Kuala Lumpur Convention Centre, Malaysia.
  • LOH, H.-S., 2016. Developing plant-based vaccines against deadly viral diseases. In: UK-Malaysia Vaccinology Workshop 2016. Selangor, Malaysia.
  • WONG, S.H.M, FANG, C.-M., LOH, H.-S. and NGAI, S.C., 2016. TRAIL, an anti-cancer agent which does not kill the healthy cells. In: UNMC Research Showcase 2016. Selangor, Malaysia.
  • LOW, S.S., TAN, M.T.T., KHIEW, P.S., LOH, H.S. and CHIU, W.S., 2015. One step green synthesis of graphene/ZnO nanocomposite for nonenzymatic hydrogen peroxide sensing. Materiali in Tehnologije / Materials and Technology. 49(5), 837–840
  • ABUBAKAR, I.B., LIM, K.-H. and LOH, H.-S., 2015. Alkaloid extracts of Ficus species and palm oil-derived tocotrienols synergistically inhibit proliferation of human cancer cells. Natural Product Research. 29(22), 2137-2140
  • YAP, V.A., LOONG, B.-J., TING, K.N., LOH, H.-S., YONG, K.-T., LOW, Y.-Y., KAM, T.-S. and LIM, K.-H., 2015. Hispidacine, an unusual 8,4′-oxyneolignan-alkaloid with vasorelaxant activity, and hispiloscine, an antiproliferative phenanthroindolizidine alkaloid, from Ficus hispida Linn. Phytochemistry. 109, 96-102
  • LIM, S.W., LOH, H.-S., TING, K.N., BRADSHAW, T.D. and ZEENATHUL, N.A., 2015. Reduction of MTT to purple formazan by vitamin E isomers in the absence of cells. Tropical Life Sciences Research. 26(1), 111-120
  • MUTHOOSAMY, K., BAI, R.G., ABUBAKAR, I.B., SUDHEER, S.M., LIM, H.N., LOH, H.S., HUANG, N.M., CHIA, C.H. and MANICKAM, S., 2015. Exceedingly biocompatible and thin-layered reduced graphene oxide nanosheets using an eco-friendly mushroom extract strategy. International Journal of Nanomedicine. 2015:10, 1505-1519
  • BALAKRISHNAN, K.N., ABDULLAH, A.A., CAMALXAMAN, S.N., QUAH, Y.W., ABBA, Y., HANI, H., LOH, H.S., KAMAL, F.M., ZEENATHUL, N.A., AINI, I., OMAR, A.R., NOORDIN, M.M. and MOHD AZMI, M.L., 2015. Complete genome sequence of rat cytomegalovirus strain ALL-03 (Malaysian strain). Genome Announcements. 3(3), e00451-15
  • CHAN, X.-Y., MUSIYCHUK, K., YUSIBOV, V., ALLAUDIN, Z.N., MOHD-LILA, M.A., MASSAWE, F. and LOH, H.-S., 2015. Molecular characteristics of plant-expressed chicken anemia virus VP3 protein in Nicotiana benthamiana. In: Plant-Based Vaccines, Antibodies and Biologics (PBVAB) 2015. Lausanne, Switzerland.
  • PANG, E.L., PEYRET, H., RAMIREZ, A., WHELAN, M, LOMONOSSOFF, G.P., LAI, K.S. and LOH, H.-S., 2015. A hepatitis B core-based production of plant virus-like particles as dengue vaccine candidate. In: Plant-Based Vaccines, Antibodies and Biologics (PBVAB) 2015. Lausanne, Switzerland.
  • LEONG, Y.K., SHOW, P.L., LAN, J.C.W. and LOH, H.-S., 2015. Thermoseparating aqueous two-phase system: recent trends and applications. Chemical Engineering Transactions. 45, 1249-1254
  • LEONG, Y.K., KOROH, F.E., SHOW, P.L., LAN, J.C.W. and LOH, H.-S., 2015. Optimisation of extractive bioconversion for green polymer via aqueous two-phase system. Chemical Engineering Transactions. 45, 1495-1500
  • LOH, H.-S., 2015. Efficient Agrobacterium-based transient expression system for plant-made biopharmaceuticals production (Invited Talk). In: International Colloquium on Recent Advances in Curriculum and Research in Biotechnology. Gazipur, Bangladesh.
  • YONG, J.S., LOW, S.S., CHIA, J.S.Y., TAN, M.T.T. and LOH, H.S., 2014. Development of enzyme-linked amperometric genosensor for detection of avian influenza viral genes. In: The 25th Intervarsity Biochemistry Seminar. National University of Malaysia, Selangor.
  • MOHAMAD-LATIFFI, M.R.R., LIM, K.H. and LOH, H.S., 2014. Antibacterial properties of a Moraceae hybrid species, Artocarpus heterophyllus x integer. In: The 25th Intervarsity Biochemistry Seminar. National University of Malaysia, Selangor.
  • ZU, H.M., LIM, S.S. and LOH, H.S., 2014. Chitosan-titanium dioxide nanotube scaffolds for proliferation and early differentiation of MG63 by functionalization with fetal bovine serum. In: The 25th Intervarsity Biochemistry Seminar. National University of Malaysia, Selangor.
  • CHAI, C.Y., LIM, S.S. and LOH, H.S., 2014. In vitro evaluation of osteoblast adhesion, proliferation and differentiation on chitosan-titanium dioxide composite scaffolds functionalized with Ca2+ ions. In: The 25th Intervarsity Biochemistry Seminar. National University of Malaysia, Selangor.
  • SANTIAGO, C., PANG, E.L., LIM, K.H., LOH, H.S. and TING, K.N., 2014. Reversal of ampicillin resistance in MRSA via inhibition of penicillin-binding protein 2a by Acalypha wilkesiana. BioMed Research International. 965348
  • LIM, S.W., LOH, H.-S., TING, K.N., BRADSHAW, T.D. and ZEENATHUL, N.A., 2014. Antiproliferation and induction of caspase-8-dependent mitochondria-mediated apoptosis by β-tocotrienol in human lung and brain cancer cell lines. Biomedicine & Pharmacotherapy. 68(8), 1105-1115
  • SANTIAGO, C., LIM, K.H., LOH, H.S. and TING, K.N., 2014. Bioactive plant metabolites reverses resistant of MRSA biofilms to ampicillin. In: International Conference on Antimicrobial Research - ICAR2014. Madrid, Spain. 204
  • WANG, E.S., LOH, H.S. and FRAY, R., 2014. Construction of a gateway-like transformation vector system for the expression of transgenes in the chloroplasts of tobacco. In: The 21st MSMBB Annual Scientific Meeting. Monash University, Selangor, Malaysia.
  • CHAN, X.Y., LOH, H.S., ZEENATHUL, N.A., MOHD-AZMI, M.L., MUSIYCHUK, K. and YUSIBOV, V., 2014. Transient expression and purification of recombinant apoptin with green fluorescence protein fusion in Nicotiana benthamiana. In: The 21st MSMBB Annual Scientific Meeting. Monash University, Selangor, Malaysia.
  • LOH, H.S., PUA, T.L., MASSAWE, F., OMAR, A.R., MUSIYCHUK, K. and YUSIBOV, V., 2014. Column chromatographic purification of soluble influenza hemagglutinin protein expressed in Nicotiana benthamiana. In: The 39th MSBMB Conference. Sepang, Malaysia.
  • LIM, S.-W., LOH, H.-S., TING, K.-N., BRADSHAW, T.D. and ZEENATHUL, N.A., 2014. Cytotoxicity and apoptotic activities of alpha-, gamma-and delta-tocotrienol isomers on human cancer cells. BMC Complementary and Alternative Medicine. 14, 469
  • ABUBAKAR, I.B., LIM, K.-H. and LOH, H.-S., 2014. Combination of low dose δ-Tocotrienol and Jerantinine A induces synergistic growth inhibition on human lung adenocarcinoma. In: Joint Malaysia-UK Symposium on Natural Product Chemistry and Drug Discovery. Kuala Lumpur, Malaysia.
  • CAMALXAMAN, S.N., ZEENATHUL, N.A., QUAH, Y.W., LOH, H.S., ZURIDAH, H., HANI, H., SHEIKH-OMAR, A.R. and MOHD-AZMI, M.L., 2013. Establishment of rat brain endothelial cells susceptible to rat cytomegalovirus ALL-03 infection. In Vitro Cellular & Developmental Biology – Animal. 49(3), 238-244
  • MOHTAR, S.H., LOH, H.S., MASSAWE, F. and OMAR, A.R., 2013. Antigenicity and immunogenicity evaluations of plant-based VP2 protein of Malaysian highly virulent infectious bursal disease virus (hvIBDV) expressed in Nicotiana tabacum. IOSR Journal of Agriculture and Veterinary Science (IOSR-JAVS). 2(6), 64-72
  • YAACOB, J.S., LOH, H.S. and MAT TAHA, R., 2013. Protein profiling and histone deacetylation activities in somaclonal variants of oil palm (Elaeis guineensis Jacq.). The Scientific World Journal. 2013, 613635
  • LIM, S.W., LOH, H.S., TING, K.N., BRADSHAW, T.D. and ZEENATHUL N.A., 2013. Acalypha wilkesiana ethyl acetate extract enhances the in vitro cytotoxic effects of α-tocopherol in human brain and lung cancer cells. International Journal of Bioscience, Biochemistry and Bioinformatics. 3(4), 335-340
  • WANG, E.S., FRAY, R., MEMARI, H.R. and LOH, H.S., 2013. In planta chloroplast engineering of the avian influenza vaccine candidates through the gateway cassettes of a reporter. In: Plant-Based Vaccines, Antibodies and Biologics (PBVA) 2013. Verona, Italy.
  • LIM, S.W., LOH, H.S., TING, K.N., BRADSHAW, T.D. and ZEENATHUL N.A., 2013. Acalypha wilkesiana ethyl acetate extract enhances the in vitro cytotoxic effects of alpha-tocopherol in human brain and lung cancer cells. In: International Conference of Biotechnology and Food Science. Beijing, China.
  • THAM, S.Y., CHAN, X.Y. and LOH, H.S., 2013. Expression of an anticancer therapeutic protein, apoptin in planta. In: The 24th Intervarsity Biochemistry Seminar. Taylor’s University Lakeside Campus, Selangor, Malaysia.
  • LEE, Y.D., WANG, E.S. and LOH, H.S., 2013. Regulation of gene expression in bacteria by plastid promoter. In: The 24th Intervarsity Biochemistry Seminar. Taylor’s University Lakeside Campus, Selangor, Malaysia.
  • LOH, F.K., CHAN, X.Y., PUA, T.L. and LOH, H.S., 2013. Preliminary study on H5N1 antigen expression for plant-based vaccine development. In: The 24th Intervarsity Biochemistry Seminar. Taylor’s University Lakeside Campus, Selangor, Malaysia.
  • LOH, H.S., LIM, S.W., TING, K.N., BRADSHAW, T.D. and ZEENATHUL N.A., 2013. The potential synergism between Acalypha wilkesiana metabolites and vitamin e isomers for the treatment of cancers. In: The 38th MSBMB Conference. Putrajaya, Malaysia.
  • MOHTAR, S.H., LOH, H.S., MASSAWE, F. and OMAR, A.R., 2013. Effect of a silencing suppressor gene towards the expression of VP2 protein of highly virulent infectious bursal disease virus in tobacco. Journal of BioScience and Biotechnology. 2(3), 159-166
  • WONG, Q.N., MAYES, S., LOH, H.S., CHIN, C.F. and MASSAWE, F., 2013. Genetic improvement of winged bean for increased productivity and nutritional security. In: The 3rd International Neglected and Underutilised Species Conference (NUS): For a Food-Secure Africa. Accra, Ghana.
  • LOH, H.S., WANG, E.S., PUA, T.L., HASMAH, M.S., FRAY, R., MASSAWE, F., TAN, C.S. and OMAR, A.R., 2012. Green vaccine factories to curb deadly poultry viral diseases. In: BIT’s 4th Annual World Congress of Vaccine 2012. Beijing, China. 67
  • PANG, E.E., WANG, E.S., CHAN, X.Y. and LOH, H.S., 2012. Molecular expression of outer membrane protein c (ompC) in planta as a vaccine candidate against fowl typhoid. In: The 23rd Intervarsity Biochemistry Seminar. University of Malaya, Kuala Lumpur, Malaysia.
  • LOONG, B.J., LOH, H.S., CHIN, J.K. and CHIANG, C.L., 2012. Surface biofunctionalisation of poly-dimethylsiloxane (PDMS) for immobilisation of antibody. In: The 3rd International Conference on Advances in Microfluidics and Nanofluidics (AMN2012). Dalian, China.
  • LIM, S.W., LOH, H.S., TING, K.N., BRADSHAW, T.D. and ZEENATHUL N.A., 2012. Combinatorial application of vitamin E isomers and Acalypha wilkesiana fractions: A potential anticancer therapeutic candidate. In: The 2nd International Conference of Life Sciences. Malang, Indonesia. 19
  • LOH, H.S., PUA, T.L., HASMAH, M.S., WANG, E.S., CHAN, X.Y., YUSIBOV, V., MASSAWE, F., OMAR, A.R. and FRAY, R., 2012. Biopharmaceuticals production using an alternative green approach (Plenary Lecture). In: The 2nd International Conference of Life Sciences. Malang, Indonesia. PL 7.3
  • OTHMAN, M., SANTIAGO, C., SPOWAGE, A.C., LOH, H.S., LIM, K.H. and TING, K.N., 2012. Inhibition of b-lactamase and penicillin binding protein 2a. In: The 15th International Biotechnology Symposium and Exhibition (IBS 2012). Daegu, Korea.
  • WANG, E.S., LOH, H.S., FRAY, R. and MEMARI, H.R., 2012. Towards development of chloroplast-based candidate vaccines against avian influenza strain H5N1. In: The 15th International Biotechnology Symposium and Exhibition (IBS 2012). Daegu, Korea.
  • LOH, H.S., PUA, T.L., YUSIBOV, V., HASMAH, M.S., MASSAWE, F., TAN, C.S. and OMAR, A.R., 2012. Recombinant plant viruses as transient expression vectors for the production of vaccine candidates against deadly poultry diseases. In: The 15th International Biotechnology Symposium and Exhibition (IBS 2012). Daegu, Korea.
  • PUA, T.L., LOH, H.S., MASSAWE, F., TAN, C.S. and OMAR, A.R., 2012. Expression of insoluble influenza neuraminidase type 1 (NA1) protein in tobacco. Journal of Tropical Life Sciences. 2(3), 62-71
  • LOH, SS, CHAN, XY and LOH, H.S., 2012. Agroinfiltration of cowpea mosaic viral vector harbouring green fluorescent protein gene. In: The 23rd Intervarsity Biochemistry Seminar. University of Malaya, Kuala Lumpur, Malaysia.
  • CAMALXAMAN, S.N., ZEENATHUL, N.A., QUAH, Y.W., ZURIDAH, H. and LOH, H.S., 2012. New estimates of CMV seroprevalence in Malaysia. Where do we go from here? Medical Journal of Malaysia. 67(2), 231
  • OTHMAN, M., LOH, H.S., WIART, C., KHOO, T.J., LIM, K.H. and TING, K.N., 2011. Optimal methods for evaluating antimicrobial activities from plant extracts. Journal of Microbiological Methods. 84(2), 161-166
  • WIJAYA, S., TING, K.N., KHOO, T.J., LIM, K.H., LOH, H.S. and WIART, C., 2011. Antibacterial and antioxidant activities of Synedrella nodiflora (L.) Gaertn. (Asteraceae). Journal of Complementary and Integrative Medicine. 8(1), 13
  • LIM, S.W., TING, K.N., ZEENATHUL N.A. and LOH, H.S., 2011. Plant secondary metabolites enhance anticancer activity of vitamin E isomers. In: The 2nd Palm International Nutra-Cosmeceutical Conference. Kuala Lumpur, Malaysia.
  • PUA, T.L., MASSAWE, F., TAN, C.S., OMAR, A.R. and LOH, H.S., 2011. Plant-based transient expression of neuraminidase of Malaysian avian influenza. In: Plant-Based Vaccines and Antibodies (PBVA) 2011. Porto, Portugal.
  • WONG, Q.N, LIM, S.W. and LOH, H.S., 2011. Investigation of anticancer effects of Acalypha wilkesiana on human liver cancer cell. In: The 22nd Intervarsity Biochemistry Seminar. UKM, Selangor, Malaysia.
  • MOHD-IBRAHIM, I. and LOH, H.S., 2011. Recent development of plant-based vaccine could be an alternative to control poultry viral diseases. In: The 22nd Intervarsity Biochemistry Seminar. UKM, Selangor, Malaysia.
  • LIM, S.W., TING, K.N., BRADSHAW, T.D., ZEENATHUL N.A., WIART, C., KHOO, T.J., LIM, K.H. and LOH, H.S., 2011. Acalypha wilkesiana extracts induce apoptosis by causing single strand and double strand DNA breaks. Journal of Ethnopharmacology. 138, 616-623
  • CHEE, J.Y., WANG, E.S., FRAY, R. and LOH, H.S., 2011. Construction of a subunit vaccine against methicillin-resistant Staphylococcus aureus (MRSA) in planta via particle bombardment. In: The 22nd Intervarsity Biochemistry Seminar. UKM, Selangor.
  • OTHMAN, M., GENAPATHYA, S., LIEW, P.S., CH’NG, Q.T., LOH, H.S., KHOO, T.J., WIART, C. and TING, K.N., 2011. Search for antibacterial agents from Malaysian rainforest and tropical plants. Natural Product Research. 25(19), 1857-1864
  • SANTIAGO, C., OTHMAN, M., LOH, H.S., LIM, K.H., WIART, C., KHOO, T.J. and TING, K.N., 2011. Anti-Methicillin resistant Staphylococcus aureus (MRSA) activity of ethyl acetate extract from Acalypha wilkesiana. In: Malaysian Pharmaceutical Society–Pharmacy Scientific Conference (MPS-PSC) 2011. Kuala Lumpur, Malaysia.
  • SANTIAGO, C., LOH, H.S., LIM, K.H., WIART, C., KHOO, T.J. and TING, K.N., 2011. Anti-methicillin resistant Staphylococcus aureus (MRSA) activity of combination of antibiotic and ethyl acetate extract from Acalypha wilkesiana. In: International Conference of Natural Products (ICNP) 2011. Putrajaya, Malaysia.
  • YAP, V.A., LIM, K.H., LOH, H.S. and TING, K.N., 2011. Comparison of anti-cancer activity between parent and hybrid species of Artocarpus heterophyllus and Artocarpus integer against breast and cervical cancer cell lines. In: International Conference of Natural Products (ICNP) 2011. Putrajaya, Malaysia.
  • LIM, S.W., TING, K.N., BRADSHAW, T.D., ZEENATHUL N.A., WIART, C., KHOO, T.J., LIM, K.H. and LOH, H.S., 2011. Combinatorial application of Acalypha wilkesiana extracts and vitamin e isomers as an alternative cancer treatment. In: International Conference of Natural Products (ICNP) 2011. Putrajaya, Malaysia.
  • TING, K.N., OTHMAN, M., TELFORD, G., CLARKE, G., BRADSHAW, T.D., KHOO, T.J., LOH, H.S., WIART, C., PRITCHARD, D. and FRY, J.R., 2011. Antioxidant, cytoprotective, growth inhibitory and immunomodulatory activities of extracts of Dysoxylum cauliflorum Hiern., a Malaysian Meliaceae. Journal of Medicinal Plants Research. 5(24), 5867-5872
  • CAMALXAMAN, S.N., ZEENATHUL, N.A., QUAH, Y.W., LOH, H.S., ZURIDAH, H., SHEIKH-OMAR, A.R. and MOHD-AZMI, M.L., 2011. Cross-reactivity of Malaysian rat cytomegalovirus strains with its human counterpart. Tropical Biomedicine. 28(3), 661-667
  • CAMALXAMAN, S.N., ZEENATHUL, N.A., QUAH, Y.W., LOH, H.S., ZURIDAH, H., HANI, H., SHEIKH-OMAR, A.R. and MOHD-AZMI, M.L., 2011. The relevance of viral culture based methods for the detection of rat cytomegalovirus ALL-03 (RCMV ALL-03) in the modern era of technology. Jurnal Veterinar Malaysia. 23(2), 1-5
  • SANTIAGO, C., OTHMAN, M., SPOWAGE, A., LOH, H.-S., LIM, K.-H. and TING, K.N., 2011. A new cure to combat antibiotic resistant bacteria. In: UNMC Research Showcase 2011. Selangor, Malaysia.
  • WANG, E.S., FRAY, R. and LOH, H.S., 2011. A green strategy to curb the advancing threat of bird flu. In: UNMC Research Showcase 2011. Selangor, Malaysia.
  • LIM, S.W., TING, K.N., ZEENATHUL N.A. and LOH, H.-S., 2011. A new hope in cancer treatment: Combinatorial application of vitamin E isomers and plant extracts. In: UNMC Research Showcase 2011. Selangor, Malaysia.
  • WANG, E.S., LOH, H.S., PUA, T.L. and ALDERSON, P.G., 2010. Construction of a candidate vaccine against avian influenza, strain H5N1 via biolistics mediation. In: The 21st Intervarsity Biochemistry Seminar. UCSI University, Selangor, Malaysia.
  • SOON, S.L., SOON, S.L., TAN, B.C., WONG, W.C. and ALDERSON, P.G., 2010. Protein profiles involving oil palm mantling phenomenon. In: The 21st Intervarsity Biochemistry Seminar. UCSI University, Selangor, Malaysia.
  • KHOO, T.J., WONG, P.C., TING, K.N., WIART, C. and LOH, H.S., 2010. HMG-CoA reductase inhibitors from secondary metabolites of Malaysia rainforest plants. In: The 21st International Symposium on Medicinal Chemistry. Brussels, Belgium.
  • CHAN, X.Y., LOH, H.S., PUA, T.L., HASMAH, M.S. and ALDERSON, P.G., 2010. In-vitro single nucleotide modification improves a strategy used in development of plant-based vaccine. In: The 21st Intervarsity Biochemistry Seminar. UCSI University, Selangor, Malaysia.
  • CHU, J., LIM, S.W., LOH, H.S., KHOO, T.J., TING, K.N., WIART, C. and BRADSHAW, T.D., 2010. In vitro anticancer activity of Acalypha wilkesiana extracts. In: UK-Malaysia Symposium on Drug Discovery and Development for Cancer. Selangor, Malaysia.
  • LOONG, B.J., LOH, H.S., PUA, T.L. and ALDERSON, P.G., 2010. Development of quantitative real-time RT-PCR for kinetic analysis of haemagglutinin (HA) expression in a plant system. In: The 21st Intervarsity Biochemistry Seminar. UCSI University, Selangor, Malaysia.
  • LOH, H.S., HASMAH, M.S., PUA, T.L., CHAN, X.Y., OMAR, A.R., MASSAWE, F. and TAN, C.S., 2010. Development of a candidate vaccine for highly virulent infectious bursal disease virus (hvIBDV) by epitope display in plant viral capsid protein. In: National Biotechnology Seminar. Selangor, Malaysia.
  • LOH, H.S., PUA, T.L., HASMAH, M.S., TAN, C.S., OMAR, A.R., MASSAWE, F. and ALDERSON, P.G., 2009. Plant viral-based strategies for development of vaccine candidates in planta (Invited Talk). In: National Conference on New Crops and Bioresources. N. Sembilan, Malaysia. 141-151
  • OTHMAN, M., FRY, J.R., TELFORD, G., BRADSHAW, T.D., WIART, C., OTHMAN, M., LOH, H.S. and TING, K.N., 2009. Bioactivities of an unstudied Malaysian rainforest plant from the Meliaceae family. In: ELRIG Drug Discovery '09. Liverpool, UK.
  • TING, K.N., WIART, C., KHOO, T.J., LOH, H.S., FRY, J.R., BRADSHAW, T.D., TELFORD, G., PRITCHARD, D.I., ZEENATHUL, N.A., OTHMAN, M., SARMIDI, M.R. and KUMARESAN, S., 2009. Strategic drug discovery research on rainforest (tropical) plants. In: Biomedical Asia 2009. Singapore.
  • MASSAWE, F., MAYES, S., LOH, H.S., ALDERSON, P.G. and AZAM-ALI, S., 2009. Research and development of underutilised crops - towards a common methodology. In: National Conference on New Crops and Bioresources. N. Sembilan, Malaysia. 29-40
  • OTHMAN, M., LOH, H.S., WIART, C., KHOO, T.J. and TING, K.N., 2009. Antimicrobial and antioxidant activities of a plant species from the Annoaceae family. In: The 23rd MSPPSM. Kuala Lumpur, Malaysia.
  • PUA, T.L., MASSAWE, F., TAN, C.S., OMAR, A.R. and LOH, H.S., 2009. Towards development of bird flu vaccine in planta. In: UNMC Graduate School‘s Conference. Selangor, Malaysia.
  • HASMAH, M.S., CHAN, X.Y., MASSAWE, F., OMAR, A.R. and LOH, H.S., 2009. Towards development of a plant-based vaccine for highly virulent infectious bursal disease virus (hvIBDV). In: UNMC Graduate School‘s Conference. Selangor, Malaysia.
  • LOH, H.S., HASMAH, M.S., PUA, T.L., MASSAWE, F., OMAR, A.R. and TAN, C.S., 2009. Plant virus-based approach for the development of vaccine candidates for poultry viral diseases. In: Plant-Based Vaccines and Antibodies (PBVA) 2009. Verona, Italy.
  • HASMAH, M.S., LOH, H.S., MASSAWE, F. and OMAR, A.R., 2009. Application of plant viral-based delivery strategy in developing a vaccine candidate for highly virulent Infectious Bursal Disease Virus (hvIBDV). In: The 21st VAM Congress. N. Sembilan, Malaysia. 87-89
  • LIM, S.W., TING, K.N., BRADSHAW, T.D., ZEENATHUL N.A. and LOH, H.S., 2009. Application of plant bioactive compounds as an alternative cancer treatment. In: UNMC Graduate School‘s Conference. Selangor, Malaysia.
  • PUA, T.L., TAN, C.S., OMAR, A.R., MASSAWE, F. and LOH, H.S., 2009. Development of plant-based vaccine candidates for Malaysian isolate of avian influenza virus (H5N1). In: Plant-Based Vaccines and Antibodies (PBVA) 2009. Verona, Italy.
  • OTHMAN, M., LOH, H.S., WIART, C., KHOO, T.J. and TING, K.N., 2009. Antimicrobial and antioxidant activities of Pseuduvaria macrophylla. In: UNMC Graduate School‘s Conference. Selangor, Malaysia.
  • LOH, H.S., OTHMAN, M., BRADSHAW, T.D., FRY, J.R., WIART, C., KHOO, T.J. and TING, K.N., 2009. Pharmacological characterization of bioactive compounds from rainforest (tropical) plants for the development of therapeutic agents. In: Biomedical Asia 2009. Singapore.
  • HASMAH, M.S., LOH H.S., MASSAWE, F. and OMAR, A.R., 2008. Construction of a vaccine candidate for highly virulent infectious bursal disease virus using plant virus-based vector. In: The 33rd MSBMB Conference. Kuala Lumpur, Malaysia. 136
  • OTHMAN, M., LOH, H.S., WIART, C., KHOO, T.J. and TING, K.N., 2008. Bioactive activities of crude extracts from two tropical plants. In: The 8th MPS Pharmacy Scientific Conference. Pahang, Malaysia. 73
  • OTHMAN, M., LOH, H.S., WIART, C., KHOO, T.J. and TING, K.N., 2008. Antibacterial activities of Duabanga grandiflora. In: The 33rd MSBMB Conference. Kuala Lumpur, Malaysia. 163
  • ZEENATHUL, N.A., CHAN, P.S., LOH, H.S., NAZRINA, C., NORAINI, A.S., CHIEW, L.S., TAN, S.S., TAN, C.G. and MOHD-AZMI, M.L., 2008. Cytomegalovirus infection in wild rat. In: The 20th VAM Congress. Putrajaya, Malaysia. 58
  • PUA, T.L., LOH, H.S., MASSAWE, F., TAN, C.S. and OMAR, A.R., 2008. Construction of a plant-based vaccine delivery vector for candidate genes of avian influenza virus, strain H5N1. In: The 33rd MSBMB Conference. Kuala Lumpur, Malaysia. 117
  • ZEENATHUL, N.A., CHIEW L.S., AINI, I., TAN, C.C., CHAN, P.S., NAZRINA, C., NORAINI, A.S., LOH, H.S., TAN, S.S., TAN, C.G. and MOHD-AZMI M.L., 2008. Cytopathic features in rat-tissue inoculated cell culture In: The 20th VAM Congress. Putrajaya, Malaysia. 79
  • LOH, H.S., MOHD-AZMI, M.L., SHEIKH-OMAR, A.R., ZAMRI-SAAD, M. and TAM, Y.J., 2007. Pathogenesis and antibody response to a cytomegalovirus infection in newborn rats. Acta Virologica. 51(1), 27-33
  • LOH, H.S., MOHD-AZMI, M.L., SHEIKH-OMAR, A.R., ZAMRI-SAAD, M. and ZEENATHUL, N.A., 2007. Molecular characterization and identification of the immediate-early (IE) genes of rat cytomegalovirus (RCMV). Jurnal Veterinar Malaysia. 19(1), 21-32
  • LOH, H.S., MOHD-AZMI, M.L., SHEIKH-OMAR, A.R. and KIEW, L.J., 2006. Pathogenicity and vertical transmission of a transplacental rat cytomegalovirus. Virology Journal. 3, 42
  • LIM, S.N., ZEENATHUL, N.A., MOHD AZMI, M.L., LAI, K.Y. and LOH, H.S., 2006. In vitro expression of truncated VP3 protein of chicken anaemia virus. In: The 18th VAM Congress. Kuala Lumpur, Malaysia. 195-197
  • LIM, S.N., ZEENATHUL, N.A., MOHD AZMI, M.L., LAI, K.Y. and LOH, H.S., 2006. Mismatching of Apoptin/VP3 nuclear localization signal and tumorigenic selective site. In: The 9th A-IMBN Conference and 16th MSMBB Scientific Meeting. Kuala Lumpur, Malaysia. 47
  • LOH, H.S., MOHD-AZMI, M.L., ZAMRI-SAAD, M. and SHEIKH-OMAR, A.R., 2005. Kinetic quantification of in vitro transcription levels of immediate-early genes of rat cytomegalovirus. In: Colloquium on Viruses of Veterinary and Public Health Importance. Selangor, Malaysia. 139-141
  • MOHD-AZMI, M.L., LOH, H.S., SHEIKH-OMAR, A.R. and ZAMRI-SAAD, M., 2003. A novel rat model facilitates vaccine development and intervention studies for the prevention of congenital cytomegalovirus infection in human. In: UPM Invention/Innovation and R&D Exhibition. Selangor, Malaysia.
  • LOH, H.S., MOHD-AZMI, M.L., LAI, K.Y., SHEIKH-OMAR, A.R. and ZAMRI-SAAD, M., 2003. Characterization of a novel rat cytomegalovirus (RCMV) infecting placenta-uterus of Rattus rattus diardii. Archives of Virology. 148, 2353-2367
  • LOH, H.S., MOHD-AZMI, M.L., ZAMRI-SAAD, M. and SHEIKH-OMAR, A.R., 2003. Transcripts of immediate-early genes of rat cytomegalovirus (RCMV). In: The 14th National Biotechnology Seminar. Penang, Malaysia. 96
  • LOH, H.S., MOHD-AZMI, M.L., SHEIKH-OMAR, A.R. and ZAMRI-SAAD, M., 2002. Detection of maternal-foetal involvement in the pathogenesis of rat cytomegalovirus (RCMV) infection. In: MSTC. Sarawak, Malaysia. 26
  • LOH, H.S., LAI, K.Y., MOHD-AZMI, M.L., SHEIKH-OMAR, A.R. and ZAMRI-SAAD, M., 2001. A new rat cytomegalovirus (RCMV) isolate of house rats (Rattus rattus diardii). In: The 2nd International Congress/13th VAM Congress and CVA-Australasia/Oceania Regional Symposium. Selangor, Malaysia. 244-245

School of Biosciences

University of Nottingham
Sutton Bonington Campus
Nr Loughborough
LE12 5RD, UK

For all enquiries please visit:
www.nottingham.ac.uk/enquire

Find us
Campus map
Room Locations on Campus