School of Pharmacy

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Maria Marlow

Associate Professor, Faculty of Science

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Biography

I am pharmacist with a PhD in drug delivery (University of Nottingham 1991) and post doctoral experience in tissue engineering (Massachusetts Institute of Technology 1991-1992) working with osteoblasts and biodegradable polymers. I have over 18 years experience in drug delivery in industry and have worked on many different drug delivery options and formulations throughout my career at Fisons, Astra and then AstraZeneca including oral, intravenous and inhaled dosage forms. Specifically I worked on AstraZeneca's metered dose inhaler SYMBICORT, for which I have a formulation patent. I have also developed formulations of poorly soluble candidate drugs. My industrial experience includes several scientific and line manager roles from 1996 leading multidisciplinary teams in product development and early development. My last industrial role in early development included the development of formulations for preclinical, toxicity and phase I/II studies. I have also project managed and led numerous technical improvement projects/teams including recently in 2010, the development of a new global process for suspension development and a global web based brochure for clinical supplies.

In May 2011, I made the transition back into academia and secured the first Gunn and Carter Senior Fellowship at De Montfort University working with Dr Geoff Smith on developing methodologies for studying bio-relevant physical form changes of drug products using terahertz spectroscopy and pulsed imaging. In Jan 2012, I was appointed as Associate Professor in Formulation Science and Pharmaceutical Materials in the School of Pharmacy. Currently I am the training director of the EPSRC CDT in Transformative Pharmaceutical Technologies and supervise 3 PhD students and cosupervise 7 students.

Expertise Summary

Drug delivery

Formulation science

Material characterisation

Teaching Summary

Pharmaceutics

MPharm

Fundamentals of Pharmacy- module convenor and physical/chemical stability of medicines

Pain module -controlled oral drug release and colloidal stability

MSc/BSc Pharmaceutical Sciences -Biopharmaceutics (PHAR1016) and Science in Industry (PHAR3022)

MSc Drug Discovery and Pharmaceutical Sciences -Formulations in drug discovery and development

Research Summary

My research is focused on developing drug delivery systems, in collaboration with clinicians that address an unmet clinical need. My current research projects focus on using injectable hydrogels… read more

Selected Publications

Current Research

My research is focused on developing drug delivery systems, in collaboration with clinicians that address an unmet clinical need. My current research projects focus on using injectable hydrogels (including supramolecular hydrogels), nanoparticles and microneedles to deliver small molecules, proteins or peptides for the treatment of cancer (skin, ovarian and brain tumours), HIV and pain. The research involves the physicochemical characterisation of these deliver systems to allow the optimisation/prediction of their in vivo performance.

Future Research

Future research is based upon using hydrogels and microneedles for long acting oligonucleotide and protein/peptide delivery and long acting injectables for globally neglected diseases

School of Pharmacy

University of Nottingham
University Park
Nottingham, NG7 2RD

For all enquiries please visit:
www.nottingham.ac.uk/enquiry