School of Pharmacy

Image of Zheying Zhu

Zheying Zhu

Associate Professor in International Pharmacy, Course Director of BSc International Pharmacy, Faculty of Science

Contact

Biography

I obtained BSc and MSc from China Pharmaceutical University, following which I was appointed as Lecturer in Pharmaceutics at the same university. I attained my PhD in the School of Pharmacy, The Robert Gordon University (Scotland, UK). After completing my PhD studies, I had worked in the Department of Pharmacy, The Chinese University of Hong Kong, at a spin-out R&D Pharm company, King's College London, and Centre of Therapeutics and Toxicology, Imperial College London, where focused on development of label-free quantitative Proteomics with its application for toxicology research in the laboratory of Professor Allan Boobis. Later I was appointed as Senior Lecturer in Pharmacology in the Department of Life Sciences, University of Bedfordshire, developing and leading the MSc Pharmacology course successfully. In 2016 I joined the School of Pharmacy at Nottingham as Associate Professor and the course Director of the BSc International Pharmacy, a part of the first UK-China Joint Clinical Pharmacy program.

Teaching Summary

New course development & management:

BSc International Pharmacy TUTCM

Module teaching delivery and management:

Lectures/workshops: BSc International Pharmacy Year 1; MPharm/BSc Year 2; BSc/MSci Pharmaceutical Science Year 3

Research Summary

My current research interest lies in drug development and understanding molecular mechanism of Alzheimer's disease and other aging associated diseases, in particular, development of in vitro and in… read more

Recent Publications

Current Research

My current research interest lies in drug development and understanding molecular mechanism of Alzheimer's disease and other aging associated diseases, in particular, development of in vitro and in vivo models for screening and pre-clinical evaluation of novel therapeutics (small drug compounds, gene therapy), through integrated application of multi-omics (transcriptomics, proteomics and metabolomics) techniques (LC-MS, OrbiSIMS, AP-MALDI) together with imaging tools. AI and machine learning techniques are explored to predict BBB permeation of drug molecules and toxicity.

Another focus of drug development is formulation and delivery systems, these include targeted delivery of nucleic acid therapeutics (iv; intranasal); nanomedicine; orally drug controlled release; transdermal/intradermal delivery for drugs and skincare products.

The research projects currently available in my group include:

1) Using AI and molecular biology tools to investigate human aging process and develop novel approaches or therapeutics for anti-aging of brain, skin or others.

2) Novel drug targets and molecular mechanism for Alzheimer's disease, involved in neuron regeneration, neuroinflammation, or stroke.

3) Gene based therapies for Alzheimer's disease and development of their delivery systems

4) The use of PROTACs technique to discover and develop novel drug candidates for Alzheimer's disease

5) The use of Drosophila melanogaster models to identify and evaluate novel therapeutic agents for Alzheimer's disease

We are always looking for new research members to join the group to experience the excitement of research and make new discoveries. Places for research students (PhD or MRes) are available on all the above projects. Please get in touch to discuss if you are interested in the research areas. For international students, there are scholarship schemes to receive support, please get in touch for up to date information.

School of Pharmacy

University of Nottingham
University Park
Nottingham, NG7 2RD

For all enquiries please visit:
www.nottingham.ac.uk/enquiry