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Natalie Mack

Assistant Professor in Biotechnology, Faculty of Science

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COUTO A, MACK NA, FAVIA L and GEORGIOU M, 2017. An apicobasal gradient of Rac activity determines protrusion form and position. Nature communications. 8, 15385
MACK NA and GEORGIOU M, 2014. The interdependence of the Rho GTPases and apicobasal cell polarity. Small GTPases. 5(2), 10
VAUGHAN L, TAN CT, CHAPMAN A, NONAKA D, MACK NA, SMITH D, BOOTON R, HURLSTONE AF and MALLIRI A, 2014. HUWE1 ubiquitylates and degrades the RAC activator TIAM1 promoting cell-cell adhesion disassembly, migration, and invasion. Cell reports. 10(1), 88-102
MACK NA, PORTER AP, WHALLEY HJ, SCHWARZ JP, JONES RC, KHAJA ASS, BJARTELL A, ANDERSON KI and MALLIRI A, 2012. β2-syntrophin and Par-3 promote an apicobasal Rac activity gradient at cell-cell junctions by differentially regulating Tiam1 activity. Nature cell biology. 14(11), 1169-80

COUTO A, MACK NA, FAVIA L and GEORGIOU M, 2017. An apicobasal gradient of Rac activity determines protrusion form and position. Nature communications. 8, 15385
MACK NA and GEORGIOU M, 2014. The interdependence of the Rho GTPases and apicobasal cell polarity. Small GTPases. 5(2), 10
VAUGHAN L, TAN CT, CHAPMAN A, NONAKA D, MACK NA, SMITH D, BOOTON R, HURLSTONE AF and MALLIRI A, 2014. HUWE1 ubiquitylates and degrades the RAC activator TIAM1 promoting cell-cell adhesion disassembly, migration, and invasion. Cell reports. 10(1), 88-102
MACK NA, PORTER AP, WHALLEY HJ, SCHWARZ JP, JONES RC, KHAJA ASS, BJARTELL A, ANDERSON KI and MALLIRI A, 2012. β2-syntrophin and Par-3 promote an apicobasal Rac activity gradient at cell-cell junctions by differentially regulating Tiam1 activity. Nature cell biology. 14(11), 1169-80
MACK NA, WHALLEY HJ, CASTILLO-LLUVA S and MALLIRI A, 2011. The diverse roles of Rac signaling in tumorigenesis. Cell cycle (Georgetown, Tex.). 10(10), 1571-81
GRIFFITHS GJ, KOH MY, BRUNTON VG, CAWTHORNE C, REEVES NA, GREAVES M, TILBY MJ, PEARSON DG, OTTLEY CJ, WORKMAN P, FRAME MC and DIVE C, 2004. Expression of kinase-defective mutants of c-Src in human metastatic colon cancer cells decreases Bcl-xL and increases oxaliplatin- and Fas-induced apoptosis. The Journal of biological chemistry. 279(44), 46113-21