Natalie Mack

Contact

• workRoom C08 Bioenergy and Brewing Science building (BABS)
  Sutton Bonington Campus
  Sutton Bonington
  Leicestershire
  LE12 5RD
  UK
• work01159516623
• Natalie.Mack@nottingham.ac.uk

Recent Publications

• COUTO A, MACK NA, FAVIA L and GEORGIOU M, 2017. An apicobasal gradient of Rac activity determines protrusion form and position. Nature communications. 8, 15385
• MACK NA and GEORGIOU M, 2014. The interdependence of the Rho GTPases and apicobasal cell polarity. Small GTPases. 5(2), 10
• VAUGHAN L, TAN CT, CHAPMAN A, NONAKA D, MACK NA, SMITH D, BOOTON R, HURLSTONE AF and MALLIRI A, 2014. HUWE1 ubiquitylates and degrades the RAC activator TIAM1 promoting cell-cell adhesion disassembly, migration, and invasion. Cell reports. 10(1), 88-102
• MACK NA, PORTER AP, WHALLEY HJ, SCHWARZ JP, JONES RC, KHAJA ASS, BJARTELL A, ANDERSON KI and MALLIRI A, 2012. β2-syntrophin and Par-3 promote an apicobasal Rac activity gradient at cell-cell junctions by differentially regulating Tiam1 activity. Nature cell biology. 14(11), 1169-80

• View all publications

• COUTO A, MACK NA, FAVIA L and GEORGIOU M, 2017. An apicobasal gradient of Rac activity determines protrusion form and position. Nature communications. 8, 15385
• MACK NA and GEORGIOU M, 2014. The interdependence of the Rho GTPases and apicobasal cell polarity. Small GTPases. 5(2), 10
• VAUGHAN L, TAN CT, CHAPMAN A, NONAKA D, MACK NA, SMITH D, BOOTON R, HURLSTONE AF and MALLIRI A, 2014. HUWE1 ubiquitylates and degrades the RAC activator TIAM1 promoting cell-cell adhesion disassembly, migration, and invasion. Cell reports. 10(1), 88-102
• MACK NA, PORTER AP, WHALLEY HJ, SCHWARZ JP, JONES RC, KHAJA ASS, BJARTELL A, ANDERSON KI and MALLIRI A, 2012. β2-syntrophin and Par-3 promote an apicobasal Rac activity gradient at cell-cell junctions by differentially regulating Tiam1 activity. Nature cell biology. 14(11), 1169-80
• MACK NA, WHALLEY HJ, CASTILLO-LLUVA S and MALLIRI A, 2011. The diverse roles of Rac signaling in tumorigenesis. Cell cycle (Georgetown, Tex.). 10(10), 1571-81
• GRIFFITHS GJ, KOH MY, BRUNTON VG, CAWTHORNE C, REEVES NA, GREAVES M, TILBY MJ, PEARSON DG, OTTLEY CJ, WORKMAN P, FRAME MC and DIVE C, 2004. Expression of kinase-defective mutants of c-Src in human metastatic colon cancer cells decreases Bcl-xL and increases oxaliplatin- and Fas-induced apoptosis. The Journal of biological chemistry. 279(44), 46113-21