Zhi Xiang Ng

Contact

• workRoom DB05 Faculty of Science and Engineering
  Malaysia Campus
  Jalan Broga
  43500 Semenyih
  Selangor Darul Ehsan
  Malaysia
• work+6 (03) 8725 3616
• ZhiXiang.Ng@nottingham.edu.my

Biography

Dr Ng Zhi Xiang is currently an Assistant Professor in the School of Biosciences, Faculty of Science and Engineering, University of Nottingham Malaysia. He obtained his PhD in Molecular Biochemistry from the University of Malaya and PGCHE from the University of Nottingham. He is also a Fellow of Advanced Higher Education (FHEA, UK) (formerly known as Higher Education Academy), a member of Malaysian Scientific Association (MSA, Malaysia), Society of Chemical Industry (SCI, London, UK) and International Society of Global Health (ISoGH, Edinburgh, UK). Currently he serves as an academic editor for two scientific journals and has involved in the peer review of more than 50 international science indexed journals.The significance of his works has been recognized in a number of research grant capture, scholarly publications, conferences and symposia.

Research record:

ORCID ID: https://orcid.org/0000-0002-9423-7206

SCOPUS AUTHOR ID: http://www.scopus.com/inward/authorDetails.url?authorID=39262232700&partnerID=MN8TOARS

Researcher ID (N-8942-2017): https://publons.com/researcher/330559/ng-zhi-xiang/

SCHOLAR ID: https://scholar.google.com/citations?user=7zI2rg0AAAAJ&hl=en

Expertise Summary

Antioxidant, metabolic diseases risk factors and biomarkers, food sciences, molecular nutrition

Teaching Summary

A module convenor for:

1) Food Materials and Ingredients (BIOS1050)

2) Practical Techniques In Human Nutrition (BIOS 2079)

3) Molecular Nutrition (BIOS 3057)

A module contributor for:

1) Undergraduate research project (BIOS 3068)

2) Biotechnology in animal physiology (BIOS 3058)

3) Applied Bioethics-Sustainable Food Production&Biotechnology and Environment (BIOS 3060)

4) Industry placement (BIOS 1059)

Research Summary

My research interest relates to both human nutrition and health that fall into three broad areas: food sciences, molecular nutrition, metabolic diseases risk factors and biomarkers. Current research… read more

Selected Publications

• LOW HC, CHILIAN WM, RATNAM W, KARUPAIAH T, MD NOH MF, MANSOR F, NG ZX and PUNG YF, 2023. Changes in Mitochondrial Epigenome in Type 2 Diabetes Mellitus. Brit J Biomed Sci. 80, 10884. doi:10.3389/bjbs.2023.10884
• CHOE, J., YONG, P.H. and NG, Z.X., 2022. The Efficacy of Traditional Medicinal Plants in Modulating the Main Protease of SARS-CoV-2 and Cytokine Storm Chemistry & Biodiversity. doi: 10.1002/cbdv.202200655
• NG, Z.X., LIM, J.X. and YONG, P.H., 2022. In search of herbal plants combination with synergistic phytochemicals content and antioxidant activity: a case for Platycladus orientalis. In: 6TH INTERNATIONAL SYMPOSIUM ON PHYTOCHEMICALS IN MEDICINE AND FOODS, Hang Zhou, China.
• YONG, P.H., LIM, J.X. and NG, Z.X., 2022. Recent advances and challenges of Platycladus orientalis in health and medicines. In: 6TH INTERNATIONAL SYMPOSIUM ON PHYTOCHEMICALS IN MEDICINE AND FOODS, Hang Zhou, China.

• View all publications

Current Research

My research interest relates to both human nutrition and health that fall into three broad areas: food sciences, molecular nutrition, metabolic diseases risk factors and biomarkers. Current research projects includes: (i) The effect of different post-harvest processing on the bio-accessibility and enzymatic inhibitory activities in selected functional foods and medicinal plants; (ii) Effects of functional biomolecules on in vitro gene and protein expression to combat non-communicable diseases, in particular diabetes and its vascular complications.

Past Research

Studies on the role of RAGE gene polymorphism and oxidative-glycation process in the development of retinopathy in type 2 diabetic patients

• LOW HC, CHILIAN WM, RATNAM W, KARUPAIAH T, MD NOH MF, MANSOR F, NG ZX and PUNG YF, 2023. Changes in Mitochondrial Epigenome in Type 2 Diabetes Mellitus. Brit J Biomed Sci. 80, 10884. doi:10.3389/bjbs.2023.10884
• HO, K.L., YONG, P.H., WANG, C.W., KUPPUSAMY, U.R., NGO, C.T., MASSAWE, F. and NG, Z.X., 2022. Peperomia pellucida (L.) Kunth and eye diseases: A review on phytochemistry, pharmacology and toxicology Journal of Integrative Medicine. doi:10.1016/j.joim.2022.02.002
• POLAŠEK, P., WAZNY, K., ADELOYE, D., SONG, P., CHAN, K.Y., BOJUDE, D.A., ALI, S., BASTIEN, S., BECERRA-POSADA, F., BORRESCIO-HIGA, F., CHEEMA, S., CIPTA, D.A., CVJETKOVIĆ, S., CASTRO, L.D., EBENSO, B., FEMI-AJAO, O., GANESAN, B., GLASNOVIĆ, A., HE, L.T., HERAUD, J.M., IGWESI-CHIDOBE, C., IVERSEN, P.O., JADOON, B., KARIM, A.J., KHAN, J., LANZA, G., LEE, S.W.H., LI, Y., LIANG, L.L., LOWE, M., ISLAM, M.M., MARUŠIĆ, A., MSHELIA, S., MANYARA, A.M., HTAY, M.N.N., PARISI, M., PEPRAH, P., SACKS, E., AKINYEMI, K.O., SHAHRAKI-SANAVI, F., SHAROV, K., ROTAROU, E.S., STANKOV, S., SUPRIYATININGSIH, W., CHAN, B.T.Y., TREMBLAY, M., TSIMPIDA, D., VENTO, S., GLASNOVIĆ, J.V., WANG, L., WANG, X., NG, Z.X., ZHANG, J.R., ZHANG, Y.F., CAMPBELL, H., CHOPRA, M., COUSENS, S., KRSTIĆ, G., MACDONALD, C., MANSOORI, P., PATEL, S., SHEIKH, A., TOMLINSON, M., TSAI, A.C., YOSHIDA, S. and RUDAN, I., 2022. Research priorities to reduce the impact of COVID-19 in low- and middle-income countries Journal of Global Health. 12, doi: 10.7189/jogh.12.09003
• HO, K.L., NG, Z.X., WANG, C.W., JUNIT, S.M., LIM, S.H., NGO, C.T., YONG, A.C.H. and YONG, P.H., 2022. Comparative Analysis of In Vitro Enzyme Inhibitory Activities and Phytochemicals from Platycladus orientalis (L.) Franco via Solvent Partitioning Method. Applied Biochemistry and Biotechnology. doi:10.1007/s12010-022-03921-9
• HO, K.L., TAN, C.G., YONG, P.H., WANG, C.W., LIM, S.H., KUPPUSAMY, U.R., NGO, C.T., MASSAWE, F. and NG, Z.X., 2022. Extraction of phytochemicals with health benefit from Peperomia pellucida (L.) Kunth through liquid-liquid partitioning Journal of Applied Research on Medicinal and Aromatic Plants. doi:10.1016/j.jarmap.2022.100392
• NG, Z.X., SOH, E.Y.W. and YONG, P.H., 2022. The influence of fermentation and drying methods on the functional activities and sensory quality of Artemisia argyi H.Lév. & Vaniot herbal tea Journal of Applied Research on Medicinal and Aromatic Plants. doi: 10.1016/j.jarmap.2022.100393
• NG, Z.X., LIM, J.X. and YONG, P.H., 2022. In search of herbal plants combination with synergistic phytochemicals content and antioxidant activity: a case for Platycladus orientalis. In: 6TH INTERNATIONAL SYMPOSIUM ON PHYTOCHEMICALS IN MEDICINE AND FOODS, Hang Zhou, China.
• YONG, P.H., LIM, J.X. and NG, Z.X., 2022. Recent advances and challenges of Platycladus orientalis in health and medicines. In: 6TH INTERNATIONAL SYMPOSIUM ON PHYTOCHEMICALS IN MEDICINE AND FOODS, Hang Zhou, China.
• CHOE, J., YONG, P.H. and NG, Z.X., 2022. The Efficacy of Traditional Medicinal Plants in Modulating the Main Protease of SARS-CoV-2 and Cytokine Storm Chemistry & Biodiversity. doi: 10.1002/cbdv.202200655
• NG, Z.X., THAN, M.J.Y. and YONG, P.H., 2021. Peperomia pellucida (L.) Kunth herbal tea: Effect of fermentation and drying methods on the consumer acceptance, antioxidant and anti-inflammatory activities Food Chemistry. 344, 128738. doi:10.1016/j.foodchem.2020.128738
• NG, Z.X. and YONG, P.H., 2021. The implication of multicultural education on students’ learning approaches in Biosciences and Pharmacy courses. Journal of Applied Research in Higher Education. doi:10.1108/JARHE-04-2021-0128
• NG, Z.X., THAN, M.J.Y. and YONG, P.H., 2021. Role of fermentation and drying in valorizing shiny bush (Peperomia pellucida (L.) Kunth) as herbal tea: a perspective from phytochemicals, functional activity and sensory quality In: 5TH INTERNATIONAL SYMPOSIUM ON PHYTOCHEMICALS IN MEDICINE AND FOODS, Nanchang, China.
• YONG, P.H., CHEW, L.Z. and NG, Z.X., 2021. Anticancer and Antioxidant Properties of Clinacanthus Nutans (Burm.f.) Lindau Against Cancer Cell Lines: A Systematic Review In: 5TH INTERNATIONAL SYMPOSIUM ON PHYTOCHEMICALS IN MEDICINE AND FOODS, Nanchang, China.
• HO, K.L., TAN, C.G., YONG, P.H., WANG, C.W., KUPPUSAMY, U.R., NGO, C.T., MASSAWE, F. and NG, Z.X., 2021. The anti-glycation and antioxidant potential of phytochemicals extracted from Peperomia pellucida (L.) Kunth In: 5TH INTERNATIONAL SYMPOSIUM ON PHYTOCHEMICALS IN MEDICINE AND FOODS, Nanchang, China.
• NG, Z.X., KOICK, Y.T.T. and YONG, P.H., 2020. Comparative analyses on radical scavenging and cytotoxic activity of phenolic and flavonoid content from selected medicinal plants Natural Product Research. 34, doi: 10.1080/14786419.2020.1749617
• NG, Z.X., SAMSURI, S.N. and YONG, P.H., 2020. Extraction of phenolic content and antioxidant activities from selected medicinal plants: Effect of solvents with different polarity In: INTERNATIONAL RESEARCH CONFERENCE ON PHARMACEUTICAL AND ALLIED SCIENCES (IRCPAS 2020), Selangor, Malaysia.
• YONG, P.H., HO, K.L., NG, P.L. and NG, Z.X., 2020. Evaluation of Phytochemicals and Antioxidant Activities of Crude and Fractionated Extracts of Selected Medicinal Plants In: INTERNATIONAL RESEARCH CONFERENCE ON PHARMACEUTICAL AND ALLIED SCIENCES (IRCPAS 2020), Selangor, Malaysia.
• NG, Z.X., SAMSURI, S.N. and YONG, P.H., 2020. The antioxidant index and chemometric analysis of tannin, flavonoid and total phenolic extracted from medicinal plant foods with the solvents of different polarities Journal of Food Processing and Preservation. 44, e14680, doi: 10.1111/jfpp.14680
• NG, Z.X., YONG, P.H. and LIM, S.Y., 2020. Customized drying treatments increased the extraction of phytochemicals and antioxidant activity from economically viable medicinal plants Industrial Crops and Products. 155, 112815, doi:10.1016/j.indcrop.2020.112815
• NG, Z. X. and ROSMAN, N. F., 2019. In vitro digestion and domestic cooking improved the total antioxidant activity and carbohydrate-digestive enzymes inhibitory potential of selected edible mushrooms JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE. 56(2), 865-877
• NG, Z. X. and SEE, A. N., 2019. Effect of in vitro digestion on the total polyphenol and flavonoid, antioxidant activity and carbohydrate hydrolyzing enzymes inhibitory potential of selected functional plant‐based foods. Journal of Food Processing and Preservation. 43(4), e13903
• MOHD SIDEK, N.N and NG, Z.X., 2019. Effect of different infusion parameters on the antioxidant activity in non-fermented and fermented teas (Camellia sinensis) In: 30th Intervarsity Biochemistry Symposium (IBS) 2019, Selangor, Malaysia.
• NG, Z.X. and KUPPUSAMY, U.R., 2019. Effects of different heat treatments on the antioxidant activity and ascorbic acid content of bitter melon, Momordica charantia Brazilian Journal of Food Technology. 22, e2018283
• ROSMAN, N.F and Z.X, NG, 2018. Optimised heat treatment and in vitro digestion improved the anti-oxidant and anti-glycemic activities of selected edible mushrooms In: Engineering and Science Students Exhibition (ESSE) 2018, Selangor, Malaysia.
• NG, Z.X. and SEE, A.N., 2018. Evaluation of the antioxidant activity and inhibitory potential on carbohydrate hydrolysing enzymes in selected traditional medicinal plants after in vitro digestion In: International conference on drug discovery and translational medicine (ICDDTM) 2018, Putrajaya, Malaysia.
• NG, Z.X. and SEE, A.N., 2018. Evaluation of the Anti-Oxidant and Anti-Glycemic Activity of Selected Traditional Medicinal Plants After In vitro Digestion (Abst.) Frontiers in Pharmacology.
• KUPPUSAMY, U.R., WONG, F.N., CHUA, K.H. and NG, Z.X., 2018. Soluble Receptor for Advanced Glycation End Products (sRAGE) as Potential Biomarker for Diabetic Retinopathy and Chronic Kidney Disease: Madridge Journal of Internal and Emergency Medicine (MJIEM) In: International Translational and Regenerative Medicine Conference 2018, Rome, Italy.
• KUPPUSAMY, U.R, NG, Z.X, WONG, F.N, TAN, J.A.M.A. and CHUA, K.H., 2017. Soluble receptor for advanced glycation end products (sRAGE) in type 2 diabetes mellitus microvascular complications In: 15TH ANNUAL MEETING OF THE SOCIETY FOR FREE RADICAL RESEARCH-INDIA (SFRR-INDIA) AND “BASIC AND APPLIED ASPECTS OF HEALTH MANAGEMENT USING RADIATION, ANTIOXIDANTS AND NUTRACEUTICALS, Mumbai, India.
• NG, Z.X. and TAN, W.C., 2017. Impact of optimised cooking on the antioxidant activity in edible mushrooms J Food Sci Technol. 54(12), 4100–4111
• NG, Z.X. and TAN, W.C., 2017. Optimized cooking of edible mushrooms: a view point from antioxidant activity In: USIM 6th NATIONAL HEALTH SEMINAR, USIM, Negeri Sembilan , Malaysia.
• LIM, J.Y. and NG, Z.X., 2016. Comparison of Polyphenol and Antioxidant Activity between Selected Organic and Conventional Vegetables in Malaysia. In: 3rd PAN ASIA BIOMEDICAL SCIENCE CONFERENCE, Kuala Lumpur, Malaysia..
• NG, ZHI XIANG, CHUA, KEK HENG and KUPPUSAMY, UMAH RANI, 2014. Proteomic analysis of heat treated bitter gourd (Momordica charantia L. var. Hong Kong Green) using 2D-DIGE FOOD CHEMISTRY. 148, 155-161
• NG, ZHI XIANG, KUPPUSAMY, UMAH RANI, IQBAL, TAJUNISAH and CHUA, KEK HENG, 2013. Receptor for advanced glycation end-product (RAGE) gene polymorphism 2245G/A is associated with pro-inflammatory, oxidative-glycation markers and sRAGE in diabetic retinopathy GENE. 521(2), 227-233
• NG, ZHI XIANG, CHUA, KEK HENG, IQBAL, TAJUNISAH and KUPPUSAMY, UMAH RANI, 2013. Soluble Receptor for Advanced Glycation End-Product (sRAGE)/Pentosidine Ratio: A Potential Risk Factor Determinant for Type 2 Diabetic Retinopathy INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 14(4), 7480-7491
• NG, ZHI XIANG, CHUA, KEK HENG, TAJUNISAH, IQBAL, PENDEK, ROKIAH and KUPPUSAMY, UMAH RANI, 2013. Attenuated levels of pro-inflammatory markers in diabetic retinopathy patients undergoing treatment with antihyperglycemic and antihypertensive drugs CLINICS. 68(2), 185-191
• NG, Z.X., KUPPUSAMY, U.R and CHUA, K.H., 2013. Diabetic Retinopathy: A Glance At Molecular Level. LAP LAMBERT Academic Publishing, Germany.
• NG, Z.X., KUPPUSAMY, U.R, TAJUNISAH, I and CHUA, K.H., 2013. Receptor for advanced glycation end-product (RAGE) gene polymorphism 2245G/A is associated with pro-inflammatory, oxidation markers and sRAGE in diabetic retinopathy. In: 20th MALAYSIAN SOCIETY OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY (MSMBB) SCIENTIFIC MEETING, University of Malaya, Kuala Lumpur, Malaysia..
• NG, ZHI XIANG, KUPPUSAMY, UMAH RANI, TAJUNISAH, IQBAL, FONG, KENNETH CHOONG SIAN and CHUA, KEK HENG, 2012. Investigation of SLC2A1 26177A/G gene polymorphism via high resolution melting curve analysis in Malaysian patients with diabetic retinopathy JOURNAL OF DIABETES AND ITS COMPLICATIONS. 26(5), 388-392
• NG, ZHI XIANG, KUPPUSAMY, UMAH RANI, TAJUNISAH, IQBAL, FONG, KENNETH CHOONG SIAN and CHUA, KEK HENG, 2012. Association analysis of-429T/C and-374T/A polymorphisms of receptor of advanced glycation end products (RAGE) gene in Malaysian with type 2 diabetic retinopathy DIABETES RESEARCH AND CLINICAL PRACTICE. 95(3), 372-377
• NG, ZHI XIANG, KUPPUSAMY, UMAH RANI, TAJUNISAH, IQBAL, FONG, KENNETH CHOONG SIAN, KOAY, ADRIAN CHOON AUN and CHUA, KEK HENG, 2012. 2245G/A polymorphism of the receptor for advanced glycation end-products (RAGE) gene is associated with diabetic retinopathy in the Malaysian population BRITISH JOURNAL OF OPHTHALMOLOGY. 96(2), 289-292
• NG, Z.X, KUPPUSAMY, U.R, POH, R, TAJUNISAH, I, KOAY, A.C, FONG, K.C and CHUA, K.H, 2012. Lack of association between Gly82Ser, 1704G/T and 2184A/G of RAGE gene polymorphisms and retinopathy susceptibility in Malaysian diabetic patients. Genetic and Molecular Research. 11(1), 455-461.
• KUPPUSAMY, U.R, NG, Z.X., CHUA, K.H., RICHARDSON, J.S. and ABDUL MALEK, S.N, 2012. Use of customized cooking methods to improve antioxidant & nutritional values of selected vegetables. In: THE 4th INTERNATIONAL CONFERENCE ON NATURAL PRODUCTS FOR HEALTH & BEAUTY (NATPRO4), Chiang Mai University, Thailand..
• NG, ZHI-XIANG, CHAI, JEN-WAI and KUPPUSAMY, UMAH RANI, 2011. Customized cooking method improves total antioxidant activity in selected vegetables INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION. 62(2), 158-163
• NG, Z.X., CHUA, K.H., TAJUNISAH, I, PENDEK, R. and KUPPUSAMY, U.R, 2011. Soluble RAGE-pentosidine ratio as a biomarker for diabetic retinopathy. In: THE 16th BIOLOGICAL SCIENCE GRADUATE CONGRESS, National University of Singapore, Singapore..
• NG, Z.X., KUPPUSAMY, U.R, TAJUNISAH, I, KOAY, A.C, FONG, K.C and CHUA, K.H., 2011. 2245G/A polymorphism of the receptor for advanced glycation end-products (RAGE) gene is associated with the development of diabetic retinopathy. In: THE 36th ANNUAL CONFERENCE OF THE MALAYSIAN SOCIETY FOR BIOCHEMISTRY & MOLECULAR BIOLOGY, Kuala Lumpur, Malaysia..