Title: Programme

Genome Science 2018
The programme is under construction, but is updated regularly


Session TimePresentation Time SpeakerTitle
Day 1 : Tuesday 4th September  (No parallel sessions).  Conference Theatre.

10:30 - 12:00


12:00 - 12:45

Registration and Lunch

12:45 - 14:30

Welcome and Keynote Speakers      Chaired by Matt Loose


12:45 - 13:00

Matt Loose

Welcome and Housekeeping


13:00 - 13:45

Keynote Speaker 1: Sergey Koren (NIH/NHGRI)

Title: Genome assembly for the long-read era.


13:45 - 14:30

Keynote Speaker 2: Professor Ewan Birney (EBI)

Title: Big Data in Biology and Medicine (working title)

14:30 - 15:00

Coffee Break

15:00 - 16:35

Evolving Technologies     Part1    Chaired By Mike Quail.   Conference Theatre.


15:00 - 15:25

Mark Akeson (UCSC)

Title: There and Back Again: Sequencing RNA with Nanopores.


15:25 - 15:55

Niall Gormley (Illumina)

Title: Sample preparation for NGS on a surface.


15:55 - 16:15

Lia Chappell (Wellcome Sanger Institute)

Title: Methods for sequencing thousands of cells in parallel


16:15 - 16:35

Barry Merriman (Roswell Biotechnologies)

Title: The Final Disruption: Molecular Electronics for DNA sequencing.

16:35 - 16:50

Coffee Break


16:50 - 18:05

Evolving Technologies     Part2     Chaired By Mike Quail

Conference Theatre


16:50 - 17:10

Cameron Frayling (Base4)

Title: An Introduction to the Base4 Sequencing Platform.


17:10 17:28

Deyra Rodriguez (New England Biolabs)

Title: Novel Approaches to Address Challenges in Sample Preparation.


17:28 - 17:40

Andy Higgs (Advanced Analytical)

Title: Automating QC of large DNA with the FEMTO Pulse.


17:40 - 18:05

Clive Brown (Oxford Nanopore Technologies)

Title: The latest from nanopore sequencing

18:05 - 19:30

Poster Session (split into two poster attending times)

(18:20 - 19:20) 'Meet the Editor' with Andrew Cosgrove, Senior Editor of Genome Biology.

Drinks and canapes sponsored by Oxford Nanopore Technologies.


Day 2 : Wednesday 5th September 

08:30 - 09:00


09:00 - 10:40  Parallel Session 1a :   Animal and Plant Genomics    Chaired by Mick Watson.  Conference Theatre.


09:00 - 09:30

Federica Di Palma (Earlham Institute)

Title: Evolution of gene regulatory networks controlling traits under natural selection in cichlids.


09:30 - 09:50

Daniel Mead (Wellcome Sanger Institute) Title: The 25 Genomes Project, sequencing a broad taxonomic assortment of UK species.


09:50- 10:10

Ramiro Alberio (University of Nottingham)

Title: Lineage segregation, X chromosome dynamics and regulation of pluripotencyduring pig embryogenesis revealed by single cell RNA-seq.


10:10 - 10:28

Seyhan Yazar (University of Edinburgh)

Title: De novo Genome and Transcriptome Assemblies of the Bare-nosed Wombat.


10:28 - 10:40

Jon Rock (Lexogen)

Title: QuantSeq: Gene expression profiling with all the trimmings.

 09:00 - 10:40  Parallel Session 1b:    Microbial Genomics    Chaired by Emily Richardson  Conference Suite 3.


09:00 - 09:25

Pedro Oliveira (Mt Sinai Hospital, New York)

Title: The chromosomal organisation of horizontal gene transfer in bacteria.


09:25 - 09:50

Gemma Langridge (University of East Anglia)

Title: Metabolic signatures of host adaptation in Salmonella enterica.


09:50- 10:10

James McInerney (University of Nottingham)

Title: Why Prokaryotes Have Pangenomes.


10:10 - 10:28

William Rowe (Science and Technology Facilities Council)

Title: Indexed variation graphs for efficient and accurate resistome profiling.


10:28 - 10:40

Ralph Vogelsang (PacBio)

Title:  See bacterial genomes in high resolution with SMRT Sequencing.


10:40 - 11:15

Coffee Break


11:15 - 13:15  Parallel Session 2a :   Clinical Genetics    Chaired by Saskia Sanderson.  Conference Theatre.


11:15 - 11:40

Cathryn Lewis (King's College London)

Title: Applying polygenic risk scores to psychiatric disorders - hype and hope.


11:40 - 12:05

D.Gareth R Evans (The University of Manchester)

Title: Breast cancer pathology and stage are better predicted by risk stratification models that include mammographic density and common genetic variants.


12:05 - 12:20

Steve Pullan (Public Health England)

Title: Nanopore sequencing for viral clinical sample investigation; In-field metagenomics from the largest ever recorded Lassa fever outbreak.


12:20 - 12:35

Greg Elgar (Genomics England)

Title: The End of the Beginning - the Genomics England 100,000 Genomes Project.


12:35 - 12:53

Kathryn Woodfine (Product Specialist, Agilent Technologies)

Title: The Agilent NGS workflow.


12:53 - 13:11

Danielle Folkard (Qiagen)

Title: QIAGEN solutions for clinical genomics.

11:15 - 13:15  Parallel Session 2b :   Eukaryotic Microbe Genomics   Chaired by Christiane Hertz-Fowler.  Conference Suite 3.



11:15 - 11:40

Rachel M. Chalmers (Public Health Wales)

Title: Cryptosporidium genomics: where have we come from and where are we going?


11:40 - 12:05

Matt Berriman (Wellcome Sanger Institute)

Title: Comparative genomics insights into the evolutionary history of malaria.


12:05 - 12:30

Matthew Fisher (Imperial College London)

Title: Big Genomics approaches to addressing Big Fungal Problems.


12:30 - 12:45

Amber Leckenby (University of Liverpool)

Title: Genomic analyses of Entamoeba histolytica using third-generation sequencing.


12:45 - 13:00

Rajan Pandey (University of Nottingham)

Title: Deciphering Plasmodium Condensin during atypical cell divisionand proliferation.


13:00 - 13:15

Rahila Sardar (Jamia Hamdard, New Delhi)

Title: Genome wide in silico analysis of Plasmodium species transcription factorsand regulators for novel drug discovery.


13:15 - 14:15 :   Lunch


14:15 - 16:00  Parallel Session 3a :   Microbial Populations     Chaired by Nick Loman    Conference Theatre.

  14:15 - 14:40 Alan Walker (Rowett Institute, Aberdeen) Title: The human gut microbiome: myths and truths.
  14:40 - 15:05 Lesley Hoyles (Nottingham Trent University)  Title: Towards understanding the role of the gut microbiome in fatty liver disease.
  15:05 - 15:20 Josh Quick (University of Birmingham) Title: Assessing ultra-deep, long-read metagenomics on Oxford Nanopore PromethION.
  15:20 - 15:35 Benjamin Thomas (Aberystwyth University) Title: Pills 'n' Thrills and Bellyaches: Using AMPLY for computational novel antibiotic discovery in really strange places.
  15:35 - 15:47 Katherine Brown (University of Cambridge) Title: Identification of viral transcripts in RNA-seq datasets from bees, mites and ants.
  15:47 - 15:59 Sarah Hemmasi (Cambridge Bioscience) Title: Standardizing Microbiomics – Removing Bias in Collection, Purification and Analyses
14:15 - 16:00  Parallel Session 3b :   Developmental Biology     Chaired by Aziz Aboobaker.  Conference Suite 3.
  14:15 - 14:40 Dario Riccardo Valenzano (Max Planck Institute For Biology Of Ageing) Title:  The genomic phylogeny of African killifishes reveals pervasive genome-wide relaxation of selection upon adaptation to annual environments
  14:40 - 15:05 Bertie Gottgens (University of Cambridge) Title: A single-cell resolution roadmap from mouse gastrulation to early organogenesis
  15:05 - 15:20 Anish Dattani (University of Oxford) Title: Epigenetic analyses of planarian stem cells demonstrate conservation of bivalent histone modifications in animal stem cells.
  15:20 - 15:35 Abdulkadir Abakir (University of Nottingham) Title: N6-methyladenosine regulates cell cycle dynamics of RNA:DNA hybrids.
  15:35 - 15:47 Alysha Taylor (University of Leeds) Title:  A Comparative Genomics Approach to Identify microRNAs Specific to PlacentalMammals.
  15:47 - 15:59 Meena Anissi (Twist Bioscience)  Title: Improving the Performance, Efficiency and Flexibility of Targeted Sequencing
16:00 - 16:20 Coffee Break     
16:20 - 18:10 :   Parallel Session 4a :   SIngle Cell Genomics     Chaired by Lia Chappell   Conference Theatre.
  16:20 - 16:50 Viginia Howick (Wellcome Sanger Institute) Title: A Malaria Cell Atlas: Understanding transcriptional variation across the Plasmodium life-cycle using single-cell RNA-seq
  16:50 - 17:20 Wolf Reik  (The Babraham Institute) Title: Single cell epigenome landscape of development and ageing
  17:20 - 17:40 Peter Vegh (Newcastle University)

Title: Discovering the diversity of human skin immune cells using single-cell RNA-seq

  17:40 - 17:52 Daniel Liber (TakaraBio) Title: ICELL8 cx: The Open Platform for Single-Cell Genomics
  17:52 - 18:10 Stephen Hague (10X Genomics) Title: Chromium System, recent and future advances.
16:20 - 18:10 :   Parallel Session 4b :   Evolutionary Genomics     Chaired by James McInerney. Conference Suite 3.
  16:20 - 16:45 William F. Martin (Dusseldorf University) Title: In search of genome number 1: Uncovering the genome of the first microbe. 
  16:45 - 17:10 Jordi Paps (University of Essex) Title: Reconstruction of the first animal genome reveals a burst of genomic novelty
  17:10 - 17:20 Fiona Whelan (University of Nottingham) Title: The co-occurrence and co-exclusion of evolving objects in prokaryotes.
  17:20 - 17:40 Silvia Busoms (John Innes Centre, Norwich) Title: Ecological and population genomics reveals fluctuating selection on migrant adaptive sodium transporter alleles in coastal Arabidopsis thaliana.
  17:40 - 17:55 Peter Mulhair (University of Leeds) Title: Gene fusion events in Metazoa – patterns of emergence and potential use asphylogenetic markers.
  17:55 - 18:10 Gabriel Rech (Institut de Biologia Evolutiva (IBE-CSIC)) Title: Unravelling transposable element diversity using long-read sequencing.

18:10 - late

Conference Dinner Sponsored by Oxford Nanopore Technologies


Day 3 : Thursday 6th September

08:30 - 09:15

Registration with extended Coffee Break

09:15 - 11:05

Computational Biology. Chaired by Richard Emes.  Conference Theatre.


09:15 - 09:35

Chris Ponting (Edinburgh)

Title: Identifying causal variants in complex disease that alter transcription factor binding


09:35 - 09:55

Devika Agarwal (University of Oxford)

Title: A meta-analysis of microglial transcriptomic datasets to prioritize disease related targets and mechanisms in neuro-inflammation and neurodegeneration in Alzheimer’s disease.


09:55 - 10:15

Mirjana Efremova (Wellcome Sanger Institute)

Title: Decoding cell-cell interactions at the maternal-fetal interface using single cell transcriptomics


10:15 - 10:25

Martin Fahrenberger (University of Regensburg)

Title: Exploring Spatial Transcriptomics: From tissue sections to gene expression patterns.


10:25 - 10:35

Sarah Bastkowski (Earlham Institute)

Title: Networks to catch the difference: Construction and analysis of Regulatory Networks applied to East African Lake Cichlids.


10:35 - 10:47

Ivan K. Lukić (Partek)

Title: Single cell RNA-Seq data analysis with Partek® Flow®


10:47 - 11:05

Wil Wellington (Product Director, Verne Global)

Title: Computational biology in the cloud. How high performance computing (HPC) within the cloud is accelerating our ability to analyse complex biological compute workloads efficiently.


11:05 - 11:35

Coffee Break


11:35 - 13:30

Closing Keynote Speakers             Chaired by Matt Loose


11:35 - 12:20

Keynote 1: Dr Kathie Grant (Public Health England)

Title: Exploiting genomics for investigating gastrointestinal infectious disease.


12:20 - 13:05

Keynote 2: Kevin Davies

Title: Observations on the Road to the $1,000 Genome.



13:05 - 13:30

Matt Loose

Prizes and Closing Business

13:30 - 14:30

Lunch (with packed lunch options)

14:30Conference Ends 


The University of Nottingham
University Park

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