Reuben O'Dea

Contact

• workRoom C28 Mathematical Sciences
  University Park
  Nottingham
  NG7 2RD
  UK
• work0115 8466167
• Reuben.Odea@nottingham.ac.uk

Teaching Summary

I teach the following modules:

• MATH1007 Linear Mathematics
• MTHS1001 Calculus and Linear Algebra

I am course director for the MSc Financial and Computational Mathematics.

Research Summary

My research interests lie in the area of mathematical biology; my main focus is the use of numerical and multiscale asymptotic methods to investigate how the interaction of processes occurring across… read more

Selected Publications

• O'DEA R, CROFTS JJ and KAISER M, 2013. Spreading dynamics on spatially constrained complex brain networks. Journal of the Royal Society, Interface / the Royal Society. 10(81), 20130016
• RD O'DEA, HM BYRNE and SL WATERS, 2013. Continuum modelling of in vitro tissue engineering: a review. In: L GERIS, ed., Computational Modeling in Tissue Engineering 10. Springer Berlin Heidelberg. 229-266
• O'DEA, R.D. and KING, J.R., 2012. Continuum limits of pattern formation in hexagonal-cell monolayers Journal of Mathematical Biology. 64(3), 579-610
• O'DEA, R.D., OSBORNE, J.M., EL HAJ, A.J., BYRNE, H.M. and WATERS, S.L., 2013. The interplay between tissue growth and scaffold degradation in engineered tissue constructs Journal of Mathematical Biology. 67(5), 1199-1225

• View all publications

Current Research

My research interests lie in the area of mathematical biology; my main focus is the use of numerical and multiscale asymptotic methods to investigate how the interaction of processes occurring across multiple spatio-temporal scales gives rise to emergent system dynamics. Particular applications of interest are tissue growth and mechanics (applied to tissue engineering and asthma) and network structure and dynamics (with applications in neuroscience and power grid operation).

Examples of current research topics include: (i) Mechanistic models of airway mechanics and remodelling in asthma; (ii) the influence of network structure on network dynamics and operation, with application in neuroscience and power grids; (iii) the application of multiphase models to tissue growth problems; (iv) ODE and cellular automata modelling of cell population dynamics with application to antimicrobial resistance (AMR); and (v) the use of multiscale asymptotic methods to aid in the development of macroscale models with which microscale (cell-level) events, such as cell growth or signalling processes, may be described. Central to much of this work is interdisciplinary collaborations, for example with colleagues in Respiratory Medicine and the Centre for Biomolecular Sciences.

The applied nature of my work allows for opportunity for interaction with industry and business via, e.g. CMMB Consultancy.

Google Scholar | Research Gate

Current PhD students: Sonia Dari, Oliver Cattell, Adam Blakey, Malvina Bozhidarova, Jacob Jepson, Sarah Brown

Previous PhD students: Charline Tessereau (2021), Oliver Smith (2021), Daniel Williamson (2020), Michael Forrester (2020), Hannah Pybus (2020), James Preston (2019), Linda Irons (2018), Regi Jurkus (2018), Elizabeth Holden (2018), Alex Rose (2018), Mayte Bonilla Quintana (2017)

Post-doctoral fellows: Oliver Smith, Michael Forrester, Hannah Pybus

Previous PDRAs: Emma McIvor (2019), Elizabeth Holden (2019), Michael Hill (2015-18), Joe Collis (2014-17), Yi-Ping Lo (2012-13)

• M FORRESTER, JJ CROFTS, SN SOTIROPOULOS, S COOMBES and RD O'DEA, 2020. The role of node dynamics in shaping emergent functional connectivity patterns in the brain Network Neuroscience.
• OLIVER SMITH, JOHN CROWE, ETIENNE FARCOT, REUBEN O'DEA and KEITH HOPCRAFT, 2020. Cascading failures in networks of heterogeneous node behavior Physical Review E: Rapid Communication. 110, 020301(R)
• IRONS, LINDA, HUANG, HUANG, OWEN, MARKUS R, O’DEA, REUBEN D, MEININGER, GERALD A and BROOK, BINDI S, 2020. Switching behaviour in vascular smooth muscle cell-matrix adhesion during oscillatory loading Journal of Theoretical Biology. 110387
• DAVID J CHAPPELL and REUBEN D O'DEA, 2020. Numerical-asymptotic models for the manipulation of viscous films via dielectrophoresis Journal of Fluid Mechanics.
• MARIA JOVE, JADE A SPENCER, MATTHEW E HUBBARD, ELIZABETH C HOLDEN, REUBEN D O'DEA, BINDI S BROOK, ROGER M PHILLIPS, STEPHEN W SMYE, PAUL LOADMAN and CHRISTOPHER J TWELVES, 2019. Cellular uptake and efflux of palbociclib in vitro in single cell and spheroid models The Journal of Pharmacology and Experimental Therapeutics. 370(1),
• SMITH, O., CROWE, J., O'DEA, R. D. and HOPCRAFT, K., I, 2019. The Price of Anarchy in flow networks as a function of node properties EPL. 127(1),
• EC HOLDEN, SJ CHAPMAN, BS BROOK and RD O'DEA, 2019. A MULTIPHASE MULTISCALE MODEL FOR NUTRIENT-LIMITED TISSUE GROWTH, PART II: A SIMPLIFIED DESCRIPTION The ANZIAM Journal.
• A BYRNE, RD O'DEA, M FORRESTER, J ROSS and S COOMBES, 2019. Next generation neural mass and field modelling Journal of Neurophysiology.
• E.C. HOLDEN, J. COLLIS, B.S. BROOK and R.D. O'DEA, 2018. A multiphase multiscale model for nutrient limited tissue growth ANZIAM Journal.
• L. IRONS, M.R. OWEN, R.D. O'DEA and B.S. BROOK, 2018. Effect of Loading History on Airway Smooth Muscle Cell-Matrix Adhesions Biophysical Journal. 114(11), 2679–2690
• HILL, MICHAEL R, PHILP, CHRISTOPHER J, BILLINGTON, CHARLOTTE K, TATLER, AMANDA L, JOHNSON, SIMON R, O'DEA, REUBEN D and BROOK, BINDI S, 2018. A theoretical model of inflammation- and mechanotransduction-driven asthmatic airway remodelling. Biomechanics and modeling in mechanobiology. 17(5), 1451-1470
• L. IRONS, J. COLLIS and R.D. O'DEA, 2017. Microstructural influences on growth and transport in biological tissue: a multiscale description. In: S. BECKER, ed., Microscale Transport Modelling in Biological Processes Elsevier.
• COLLIS, J, BROWN, DL, HUBBARD, ME and O'DEA, RD, 2017. Effective Equations Governing an Active Poroelastic Medium Proceedings of the Royal Society A. 473, 20160755
• COLLIS J, HUBBARD ME and O'DEA RD, 2017. A multiscale analysis of drug transport and response for a multiphase tumor model European Journal of Applied Mathematics. 28(3), 499-534
• MAYTE BONILLA QUINTANA, KYLE CA WEDGWOOD, REUBEN D O'DEA and STEPHEN COOMBES, 2017. An analysis of waves underlying grid cell firing in the medial entorhinal cortex. The Journal of Mathematical Neuroscience. 7(9),
• KANAD MANDKE, JIL MEIER, MATTHEW J. BROOKES, REUBEN D O'DEA, PIET VAN MIEGHEM, CORNELIS J. STAM, ARJAN HILLEBRAND and PREJAAS TEWARIE, 2017. Comparing multilayer brain networks between groups: Introducing graph metrics and recommendations NeuroImage.
• A. ROSE, R.D. O'DEA and K.I. HOPCRAFT, 2016. Price of anarchy on heterogeneous traffic-flow networks Physical Review E. 94(3), 032315/1-12
• J. COLLIS, M.E. HUBBARD and R.D. O'DEA, 2016. Computational Modelling of Multiscale Mixture Models with Application to Tumour Growth Computer Methods in Applied Mechanics and Engineering. 309, 554–578
• J.J. CROFTS, M. FORRESTER and R.D. O'DEA, 2016. Structure-function clustering in multiplex brain networks Europhysics Letters. 116(1), 18003
• O'DEA, R. D., NELSON, M. R., EL HAJ, A. J., WATERS, S. L. and BYRNE, H. M., 2015. A multiscale analysis of nutrient transport and biological tissue growth in vitro MATHEMATICAL MEDICINE AND BIOLOGY-A JOURNAL OF THE IMA. 32(3), 345-366
• YI-PING LO, REUBEN D O'DEA, JONATHAN J CROFTS, CHEOL E HAN and MARCUS KAISER, 2015. A geometric network model of intrinsic grey-matter connectivity of the human brain Scientific Reports. 5,
• J.R. KING and R.D. O'DEA, 2015. Pushed and pulled fronts in a discrete reaction–diffusion equation Journal of Engineering Mathematics. 1-28
• O'DEA R, CROFTS JJ and KAISER M, 2013. Spreading dynamics on spatially constrained complex brain networks. Journal of the Royal Society, Interface / the Royal Society. 10(81), 20130016
• O'DEA, R.D., OSBORNE, J.M., EL HAJ, A.J., BYRNE, H.M. and WATERS, S.L., 2013. The interplay between tissue growth and scaffold degradation in engineered tissue constructs Journal of Mathematical Biology. 67(5), 1199-1225
• O'DEA RD and KING JR, 2013. The isolation of spatial patterning modes in a mathematical model of juxtacrine cell signalling. Mathematical medicine and biology : a journal of the IMA. 30(2), 95-113
• RD O'DEA, HM BYRNE and SL WATERS, 2013. Continuum modelling of in vitro tissue engineering: a review. In: L GERIS, ed., Computational Modeling in Tissue Engineering 10. Springer Berlin Heidelberg. 229-266
• O'DEA, R.D. and KING, J.R., 2012. Continuum limits of pattern formation in hexagonal-cell monolayers Journal of Mathematical Biology. 64(3), 579-610
• O'DEA, R.D. and KING, J.R., 2011. Multiscale analysis of pattern formation via intercellular signalling Mathematical Biosciences. 231(2), 172-185
• OSBORNE JM, O'DEA RD, WHITELEY JP, BYRNE HM and WATERS SL, 2010. The influence of bioreactor geometry and the mechanical environment on engineered tissues. Journal of biomechanical engineering. 132(5), 051006
• O'DEA, R.D., WATERS, S.L. and BYRNE, H.M., 2010. A multiphase model for tissue construct growth in a perfusion bioreactor. Mathematical Medicine and Biology. 27(2), 95-127
• RD O'DEA, SL WATERS and HM BYRNE, 2008. A two-fluid model for tissue growth within a dynamic flow environment European Journal of Applied Mathematics. 19, 607-634
• RD O'DEA and SL WATERS, 2006. Flow and solute transport in a twisting tube Journal of Fluid Mechanics. 562, 173-182