Tuesday, 05 November 2019
A new wearable ‘bike helmet’ style brain scanner, that allows natural movement during scanning, has been used in a study with young children for the first time. This marks an important step towards improving our understanding of brain development in childhood.
In a paper published today in Nature Communications, researchers from the Sir Peter Mansfield Imaging Centre at the University of Nottingham, working in collaboration with researchers from the University of Oxford and UCL, demonstrate how they have enhanced their ground-breaking Magnetoencephalography (MEG) technology with a novel helmet design that they used to measure brain activity in young children engaging in natural activities.
As well as providing a new way to measure healthy brain function across the lifespan, it also opens up the opportunity to study a range of neurological and mental health conditions in children, including epilepsy and autism.
Brain cells operate and communicate by producing electrical currents. These currents generate tiny magnetic fields that can be detected outside the head. Researchers use MEG to map brain function by measuring these magnetic fields. This allows for a millisecond-by-millisecond picture of which parts of the brain are engaged when we undertake different tasks, such as speaking or moving.
The foundations for human cognition are laid down in the first decades of life, but there have always been limited ways to study them due to restrictions in brain scanning technology. A particular problem has always been movement and the fact that the large traditional fixed scanners have always required patients to stay completely still. Not only does this fail to give an accurate picture of the brain operating in a natural environment, but it also places severe restrictions on who can be scanned, with children representing the biggest challenge.
Wearable quantum technology
The research team in Nottingham have solved this problem by using new ‘quantum’ sensors which are very light in weight. This means that MEG technology, which traditionally requires a half tonne ‘one-size-fits-all’ machine, is reduced to a 500 g helmet which can adapt to any head size. Because the new sensors can be placed very close to the head, the amount of signal that they can pick up is vastly increased compared to conventional equipment (which requires sensors to be kept very cold (-269 degrees) and therefore far from the head). The research team have also developed special electromagnetic coils which enable accurate control of background magnetic fields, allowing individuals to be scanned whilst they move freely.
Ryan continues: “The initial prototype scanner was a 3D printed helmet that was bespoke – in other words only one person could use it. It was very heavy and quite scary to look at. Here, we wanted to adapt it for use with children, which meant we had to design something much lighter and more comfortable but that still allowed good enough contact with the quantum sensors to pick up signals from the brain. We designed and built a new bike helmet style design and using this we were able to successfully analyse brain activity of a 2 and 5-year-old whilst they were doing an everyday activity, in this case watching TV whilst their hands were being stroked by their mum. They were able to move around and act naturally whilst doing this. To show that the system is equally applicable to older children, we used it, with a larger helmet, to scan a teenager playing a computer game.”
As well as looking at children’s brain activity, the researchers used the new scanner to examine brain activity in an adult learning a musical instrument – this scenario provides a way to examine brain activity whilst someone engages in a natural task, but was unthinkable with conventional MEG equipment because the act of playing the instrument requires head and arm movement, which has previously not been possible.
This study is a hugely important step towards getting MEG closer to being used in a clinical setting, showing it has real potential for use in children. The challenge now is to expand this further, realising the theoretical benefits such as high sensitivity and spatial resolution, and refining the system design and fabrication, taking it away from the laboratory and towards a commercial product.
Professor Richard Bowtell, Director of the Sir Peter Mansfield Imaging Centre, who was also involved in the research, said: “This is a really exciting development, which moves us towards a wearable brain MEG technology that can be used in adults and children. Collaboration with an interdisciplinary team of researchers from three universities has been key to the success of this work.”
The University of Nottingham is part of the UK Quantum Technology Hub and has recently been awarded funding to develop this MEG research further to take it closer to real-world application.
More information on the is available from Ryan Hill at the University of Nottingham,firstname.lastname@example.org Jane Icke Media Relations Manager for the Faculty of Science at the University of Nottingham, on +44 (0)115 951 5751 email@example.com.
Our academics can now be interviewed for broadcast via our Media Hub, which offers a Quicklink fixed camera and ISDN line facilities at Jubilee campus. For further information please contact a member of the Press Office on +44 (0)115 951 5798, email
For up to the minute media alerts,
follow us on Twitter
Notes to editors:
The University of Nottingham is a research-intensive university with a proud heritage. Studying at the University of Nottingham is a life-changing experience and we pride ourselves on unlocking the potential of our students. We have a pioneering spirit, expressed in the vision of our founder Sir Jesse Boot, which has seen us lead the way in establishing campuses in China and Malaysia - part of a globally connected network of education, research and industrial engagement. Ranked 103rd out of more than 1,000 institutions globally and 18th in the UK by the QS World University Rankings 2022, the University’s state-of-the-art facilities and inclusive and
disability sport provision is reflected in its crowning as The Times and Sunday Times Good University Guide 2021 Sports University of the Year. We are ranked eighth for research power in the UK according to
REF 2014. We have
six beacons of research excellence helping to transform lives and change the world; we are also a major employer and industry partner - locally and globally. Alongside Nottingham Trent University, we lead the Universities for Nottingham initiative, a pioneering collaboration which brings together the combined strength and civic missions of Nottingham’s two world-class universities and is working with local communities and partners to aid recovery and renewal following the COVID-19 pandemic.