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muscles-and-ageing

New research network will aim to improve muscle resilience throughout people’s lifespan

Tuesday, 15 March 2022

Experts from the University of Nottingham will be part of a new national research network to tackle challenges in ageing.

The Nottingham researchers will join colleagues from 27 other universities, who will collaborate to create 11 new national networks aimed at transforming ageing research in the UK, funded with £2 million from the Biotechnology and Biological Sciences Research Council (BBSRC) and the Medical Research Council (MRC).

Dr Mathew Piasecki, Assistant Professor of Clinical, Metabolic & Molecular Physiology in the Centre Of Metabolism, Ageing & Physiology (COMAP) in the School of Medicine at Nottingham, will join the MyAge (Muscle resilience across the life course: from cells to society) network, which is led by scientists at the University of Southampton.

Previous reviews of how to boost ageing research in the UK have found research efforts to be fragmented, focusing on single aspects of ageing. Now these networks aim to provide researchers with strong interdisciplinary platforms to integrate expertise and knowledge across disciplines to deliver a better understanding of the biological mechanisms of ageing and how to increase healthy lifespan and quality of life in old age.

Over the course of the two-year project, they aim to build new collaborations and hypotheses for the future of research in this area and develop a roadmap to interventions that can achieve five more years of independent living. Previous reviews of how to boost ageing research in the UK have found research efforts to be fragmented, focusing on single aspects of ageing. Now these networks aim to provide researchers with strong platforms to integrate expertise and knowledge. They will aim deliver a better understanding of the biological mechanisms of ageing and how to increase healthy lifespan and quality of later life.

Working alongside the public, industry partners, charities, policymakers and health practitioners, the networks aim to translate findings into future policy, public health and new therapies.

MyAge brings together experts from different disciplines and sectors to understand the fundamental mechanisms behind muscle ageing.

Nottingham has a strong background in ageing research with the Centre for Musculoskeletal Ageing Research (CMAR) and several arms of the NIHR Nottingham biomedical Research Centre (BRC). As part of the newly formed MyAge Network, we hope to bring together researchers, members of the public and organisations with a multi-disciplinary approach to help shape the future of ageing research.”
Dr Mathew Piasecki, Assistant Professor of Clinical, Metabolic & Molecular Physiology in the Centre Of Metabolism, Ageing & Physiology (COMAP) in the School of Medicine

Professor Melanie Welham, Executive Chair of the Biotechnology and Biological Sciences Research Council, said: "At the heart of improved health and wellbeing is a deep, integrated understanding of the fundamental mechanisms that contribute to maintaining health across the full life course. An understanding that is underpinned by collaboration, partnerships and shared knowledge. By funding the Ageing Networks, we're not only addressing a major societal challenge - we're also stimulating multidisciplinary research and innovation, with the potential for some really exciting breakthroughs."

Professor John Iredale, interim Executive Chair of Medical Research Council, said: “How to keep people healthier as they live longer is one of the biggest challenges facing 21st century medicine and our society. To make greater progress we need to transform how we conduct ageing research – both by bringing together scientists from many disciplines with the public, clinicians, policymakers and industry. The new networks we’re funding will build UK-wide collaborations to better understand the fundamentals of ageing, paving the way towards the development of novel interventions to prevent, halt or reverse aberrant ageing.”

CharlotteAnscombe
Charlotte Anscombe - Media Relations Manager - Faculty of Medicine and Health Sciences
Email: charlotte.anscombe@nottingham.ac.uk
Phone: 0115 748 4417
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About the University of Nottingham

Ranked 32 in Europe and 16th in the UK by the QS World University Rankings: Europe 2024, the University of Nottingham is a founding member of the Russell Group of research-intensive universities. Studying at the University of Nottingham is a life-changing experience, and we pride ourselves on unlocking the potential of our students. We have a pioneering spirit, expressed in the vision of our founder Sir Jesse Boot, which has seen us lead the way in establishing campuses in China and Malaysia - part of a globally connected network of education, research and industrial engagement.

Nottingham was crowned Sports University of the Year by The Times and Sunday Times Good University Guide 2024 – the third time it has been given the honour since 2018 – and by the Daily Mail University Guide 2024.

The university is among the best universities in the UK for the strength of our research, positioned seventh for research power in the UK according to REF 2021. The birthplace of discoveries such as MRI and ibuprofen, our innovations transform lives and tackle global problems such as sustainable food supplies, ending modern slavery, developing greener transport, and reducing reliance on fossil fuels.

The university is a major employer and industry partner - locally and globally - and our graduates are the second most targeted by the UK's top employers, according to The Graduate Market in 2022 report by High Fliers Research.

We lead the Universities for Nottingham initiative, in partnership with Nottingham Trent University, a pioneering collaboration between the city’s two world-class institutions to improve levels of prosperity, opportunity, sustainability, health and wellbeing for residents in the city and region we are proud to call home.

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