New stress hormone study asks, is COVID-19 affecting your mental health?

Monday, 06 April 2020

Scientists are looking for volunteers to take part in a major new study to understand how the COVID-19 pandemic is affecting the physical and emotional health of people in the UK.

The COVID-19 Stress and Health Study, is being carried out by experts at the University of Nottingham, King’s College London and with the support of the stress hormone testing company MyFertile. The survey is UK-wide and will explore the emotional and physical impact of COVID-19 on the health of our nation.

The COVID-19 pandemic has resulted in unprecedented disruption to the fabric of society, the health service and economy. Social distancing measures have been introduced to slow the spread of the virus and this new and constrained way of living, as well as the other challenges resulting from the pandemic, are already likely to be affecting emotional and physical well-being.

The new study will examine these effects by taking repeated assessments of emotional well-being in a sample of the population using questionnaires and by collecting samples of hair which contains stress hormones.

Kavita Vedhara, Professor of Health Psychology, at the University of Nottingham, is leading the study. She says: “We want to understand how the COVID-19 pandemic is affecting the physical and emotional health of people in the UK.

“We have worked in the area of stress and health for 30 years now, and one of the key things we’ve learnt is that when we experience stressful situations for protracted periods of time, such as during this pandemic, it can have real implications for our health and wellbeing. So, we are seeking to understand, whether and how the pandemic is affecting us emotionally and physically.”

Professor Kavita Vedhara

The team will do this in two ways. Firstly, participants will be asked to complete a short online survey on three occasions; on entry into the study, 12 weeks later, and potentially again after a change in social distancing has been introduced.

Participants will also be asked to provide a small sample of hair for later measurement of the stress hormone cortisol.

Professor Vedhara explains: “Cortisol is really important in regulating the normal functioning of our body, in particular it’s important in regulating how our immune system works, so you can see how levels of this hormone might be really important in determining our future physical health.  The reason we are measuring it in hair is twofold - firstly because it will be really simple and easy for people to do at home, but also – because it is an incredibly reliable way of looking at long term measures of this hormone.

“Providing these hair samples will allow us to explore whether any stress you experience today and in the coming weeks could affect your health in the future. We will be seeking funding to measure cortisol in these samples at the end of the study.”

Once the team has collected the data, the first outcome of interest will be to look at the emotional impact of the pandemic in its first few weeks, in particular looking at levels of anxiety and depression.

They will then consider how these effects on emotional well-being change after 12 weeks of living with the pandemic; and what happens as and when there are changes in social distancing regulations

The team will also examine whether the emotional effects are associated with measurable physical changes by assessing how levels of the hormone cortisol change over the 12-week period.

Recruitment to the first phase of the study is only open for the month of April so that the team can capture the early effects of the pandemic. So please visit the study website – for more information on how you can take part.

Story credits

For more information please contact Professor Kavita Vedhara from the School Medicine at the University of Nottingham, email or Charlotte Anscombe Media Relations Manager for the Faculty of Medicine and Health Sciences on +44 (0)115 951 5793 or

Charlotte Anscombe - Media Relations Manager - Faculty of Medicine and Health Sciences
Phone: 0115 748 4417

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