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Case Studies



nmCS in Action

The nmRC Commercial Services team is eager to help with your  materials analytical challenges. Have a look below at a range of case studies showcasing the materials analytical capabilities at the nmRC and wider UoN, and how they have been deployed to solve a number of industrial problems or collaborative research projects

Could we offer insight on or help answer your problem? Could we work with you to engage in a groundbreaking project? To see if the expertise or facilities at the nmRC can benefit you or your initiative please get in touch.

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Case Studies

Case study 1

Spray dried drug loaded polymeric microparticles

Using Atomic Force Microscopy (AFM) to characterise the surface strucutral and mechanical properties and their effect on performance in paramaceuticals

Case study 2

Visualising protein and surfactant distribution in PLGA microspheres

A correlative techniques study to describe the surface and 3D chemical distribution of surfactant and protein components in micro particulate formulations


Case study 3

Effect of excipients on salt disproportionation during dissolution

An in-situ Raman imaging study to understand the dissolution behaviour of pharmaceutical formulations


Case study 4

Imaging probiotic coatings in pan bread

Scanning Electron Microscopy (SEM) for probing the thickness of probiotic films on pan bread

Case study 5

Characterising bleached hair damage

A surface science study to reveal the physical and chemical changes to hair fibres during bleaching

Case study 6

Performance fuel engineering

A Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) study to examine the consituents of deposits accumulated in fuel filters

Case study 7

Textile contamination

Identification of a contaminent present in bulk textile production using Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS)


Case study 8

Soot-in-oil diagnostics

A Transmission Electron Microscopy (TEM) and Nanoparticle Tracking Analysis (NTA) study to examine how characteristics of soot particles affect the level of engine wear and fuel consumption


Case study 9

Polymer composition and spatial distribution

X-ray Photoelectron Spectroscopy (XPS) to identify thin films of polymers on the surfaces of materials


Case study 10

Characterising 3D printed electronics

A correlative techniques study to analyse the polymer-metal interface and conductive metal layer in 3D inkjet printed products

Case study 11

Porous magnetic microspheres for biomedical applications

Using Mineral Liberation Analysis (MLA) to automate the quantification of mineral compositions and distributions in polished samples

Case study 12

Transmembrane electron transport using carbon nanotube porins

A cryogenic Transmission Electron Microscopy (TEM) study to provide morphological and chemical information on bipolar electrodes

Case study 13

Antibiotic vancomycin induces complextion and aggregation of mucins

Investigating complextion/depletion interactions for model muscin systems using Environmental SEM (ESEM)

Case study 14

Protein analysis on surfaces

A 3D OrbiSIMS study to analyse protiens in their native state using a soft ionisation gas cluster ion source.

Case study 15

Performance fuel engineering

Correlatively characterising fuel injector deposits to realise reasons for poor efficiency and air quality

Battery case study

Investigating the internal structure of Mg ion batteries

FIB lift out and TEM of Mg ion battery working electrode deposits to understand performance issues over time


Particle case study

Functional and coloured polymer powders for laser sintering

Correlative materials characterisation of polymer particle coatings to introduce functionality and sustainability

Case study 18

Understanding the structure and composition of Li ion battery materials

FIB-SEM-EDS analysis to verify homogeneity of Nickel Manganese Cobalt (NMC) cathodes



Nanoscale and Microscale Research Centre

Cripps South building
University of Nottingham
University Park
Nottingham, NG7 2RD

telephone: +44 (0) 115 95 15046
email: nmcs@nottingham.ac.uk