LINKE, FRANZISKA, JOHNSON, JAMES E. C., KERN, STEFANIE, BENNETT, CHRISTOPHER D., LOURDUSAMY, ANBARASU, LEA, DANIEL, CLIFFORD, STEVEN C., MERRY, CATHERINE L. R., STOLNIK, SNOW, ALEXANDER, MORGAN R., PEET, ANDREW C., SCURR, DAVID J., GRIFFITHS, RIAN L., GRABOWSKA, ANNA M., KERR, IAN D. and COYLE, BETH, 2023. Identifying new biomarkers of aggressive Group 3 and SHH medulloblastoma using 3D hydrogel models, single cell RNA sequencing and 3D OrbiSIMS imaging ACTA NEUROPATHOLOGICA COMMUNICATIONS. 11(1),
MENDONCA, TANIA, LIS-SLIMAK, KATARZYNA, MATHESON, ANDREW B., SMITH, MATTHEW G., ANANE-ADJEI, AKOSUA B., ASHWORTH, JENNIFER C., CAVANAGH, ROBERT, PATERSON, LYNN, DALGARNO, PAUL A., ALEXANDER, CAMERON, TASSIERI, MANLIO, MERRY, CATHERINE L. R. and WRIGHT, AMANDA J., 2023. OptoRheo: Simultaneous in situ micro-mechanical sensing and imaging of live 3D biological systems COMMUNICATIONS BIOLOGY. 6(1),
JAMES, JENNA R., CURD, JOHNATHAN, ASHWORTH, JENNIFER C., ABUHANTASH, MAYS, GRUNDY, MARTIN, SEEDHOUSE, CLAIRE H., ARKILL, KENTON P., WRIGHT, AMANDA J., MERRY, CATHERINE L. R. and THOMPSON, ALEXANDER, 2023. Hydrogel-Based Pre-Clinical Evaluation of Repurposed FDA-Approved Drugs for AML INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 24(4),
HANSON, PETRA, ARKILL, KENTON P., MERRY, CATHERINE L. R., HUSSAIN, MOHAMMED S., MEERSMANN, THOMAS, RANDEVA, HARPAL S., PAVLOVSKAYA, GALINA E., O'HARE, PAUL and BARBER, THOMAS M., 2022. Novel perspectives of sodium handling in type 2 diabetes mellitus EXPERT REVIEW OF ENDOCRINOLOGY & METABOLISM. 17(4), 333-341
LINKE, FRANZISKA, ALDIGHIERI, MACHA, LOURDUSAMY, ANBARASU, GRABOWSKA, ANNA M., STOLNIK, SNOW, KERR, IAN D., MERRY, CATHERINE L. R. and COYLE, BETH, 2021. 3D hydrogels reveal medulloblastoma subgroup differences and identify extracellular matrix subtypes that predict patient outcome JOURNAL OF PATHOLOGY. 253(3), 326-338 THOMPSON, J. L., PIJUAN-GALITO, S., ASHWORTH, J. C., NIZAMUDEEN, Z., BOVEE, J., SMITH, J., HOOK, A., ARKILL, K. P., ALEXANDER, M. R., KJELLEN, L. and MERRY, C. L. R., 2021. Investigating glycosaminoglycans in development using human stem cells and fully defined 3D cell culture environments INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY. 102(2), 130-131
HOOK, ANDREW L., HOGWOOD, JOHN, GRAY, ELAINE, MULLOY, BARBARA and MERRY, CATHERINE L. R., 2021. High sensitivity analysis of nanogram quantities of glycosaminoglycans using ToF-SIMS Communications Chemistry. 4(1), VINEL, CLAIRE, ROSSER, GABRIEL, GUGLIELMI, LOREDANA, CONSTANTINOU, MYRIANNI, POMELLA, NICOLA, ZHANG, XINYU, BOOT, JAMES R., JONES, TANIA A., MILLNER, THOMAS O., DUMAS, ANAELLE A., RAKYAN, VARDHMAN, REES, JEREMY, THOMPSON, JAMIE L., VUONONVIRTA, JUHO, NADKARNI, SUCHITA, EL ASSAN, TEDANI, ALEY, NATASHA, LIN, YUNG-YAO, LIU, PENTAO, NELANDER, SVEN, SHEER, DENISE, MERRY, CATHERINE L. R., MARELLI-BERG, FEDERICA, BRANDNER, SEBASTIAN and MARINO, SILVIA, 2021. Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma NATURE COMMUNICATIONS. 12(1),
MACIEJ-HULME, MARISSA L., DUBAISSI, EAMON, SHAO, CHUN, ZAIA, JOSEPH, AMAYA, ENRIQUE, FLITSCH, SABINE L. and MERRY, CATHERINE L. R., 2021. Selective Inhibition of Heparan Sulphate and Not Chondroitin Sulphate Biosynthesis by a Small, Soluble Competitive Inhibitor INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 22(13),
JOHNSON, B. B., HOLMES, T. L., THOMPSON, J. L., LORD, M., DENNING, C., WHITELOCK, J., MERRY, C. L. R. and SMITH, JAMES, 2021. A CRISPR/Cas9 in vitro human-induced pluripotent stem cell (hiPSC) model to investigate the role of perlecan in cardiovascular fibrotic disease INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY. 102(2), 126-127
PIJUAN-GALITO, S., THOMPSON, J. L., LEWIS, L. C., TAMM, C., ANNEREN, C., DENNING, C. and MERRY, C. L. R., 2021. Inter-alpha-inhibitor supports in vitro expansion of both primed and naive human pluripotent stem cells in defined, xeno-free conditions INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY. 102(2), 133-134
MERRY, CATHERINE L. R., 2021. Exciting New Developments and Emerging Themes in Glycosaminoglycan Research JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY. 69(1), 9-11
ASHWORTH JC, THOMPSON JL, JAMES JR, SLATER CE, PIJUAN-GALITO S, LIS-SLIMAK K, HOLLEY RJ, MEADE KA, THOMPSON A, ARKILL KP, TASSIERI M, WRIGHT AJ, FARNIE G and MERRY, C. L. R., 2020. Peptide gels of fully-defined composition and mechanics for probing cell-cell and cell-matrix interactions in vitro Matrix Biology. 85-86, 15-33 ASHWORTH JC, MORGAN RL, LIS-SLIMAK K, MEADE KA, JONES S, SPENCE K, SLATER CE, THOMPSON JL, GRABOWSKA AM, CLARKE RB, FARNIE, G and MERRY CLR, 2020. Preparation of a User-Defined Peptide Gel for Controlled 3D Culture Models of Cancer and Disease JOVE - Journal of Visualized Experiments. JOHNSON, JAMES, LINKE, FRANZISKA, MERRY, CATHERINE L. R. and COYLE, BETH, 2020. ELUCIDATING HOW NOVEL EXTRACELLULAR MATRIX SUBTYPES DIFFERENTIALLY IMPACT THE SURVIVAL OF MEDULLOBLASTOMA SUBGROUPS NEURO-ONCOLOGY. 22, 405-405
SCHNEEBERGER, PAULINE E., VON ELSNER, LEONIE, BARKER, EMMA L., MEINECKE, PETER, MARQUARDT, IRIS, ALAWI, MALIK, STEINDL, KATHARINA, JOSET, PASCAL, RAUCH, ANITA, ZWIJNENBURG, PETRA J. G., WEISS, MARJAN M., MERRY, CATHERINE L. R. and KUTSCHE, KERSTIN, 2020. Bi-allelic Pathogenic Variants in HS2ST1 Cause a Syndrome Characterized by Developmental Delay and Corpus Callosum, Skeletal, and Renal Abnormalities AMERICAN JOURNAL OF HUMAN GENETICS. 107(6), 1044-1061
THOMPSON, J. L., PIJUAN-GALITO, S., ASHWORTH, J. C., DOWDING, K. S., NASIR, A., SMITH, J. G. W., WILPSHAAR, T., BOVEE, J., LIU, J., DENNING, C., ALEXANDER, M. R. and MERRY, C. L. R., 2018. Matrix-inspired biomaterials for cell phenotype control INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY. 99(6), A3-A3
LINKE, FRANZISKA, MERRY, CATHERINE L. R., GRABOWSKA, ANNA M., STOLNIK-TRENKIC, SNOW, KERR, IAN D. and COYLE, BETH, 2018. MODELLING MEDULLOBLASTOMA INVASION AND CHEMORESISTANCE IN A 3D HYALURONAN HYDROGEL SYSTEM NEURO-ONCOLOGY. 20, 137-137
BORLAND, SAMANTHA J., MORRIS, THOMAS G., BORLAND, SHONA C., MORGAN, MARK R., FRANCIS, SHEILA E., MERRY, CATHERINE L. R. and CANFIELD, ANN E., 2017. Regulation of vascular smooth muscle cell calcification by syndecan-4/FGF-2/PKC alpha signalling and cross-talk with TGF beta CARDIOVASCULAR RESEARCH. 113(13), 1639-1652
AYERST, BETHANIE I., MERRY, CATHERINE L. R. and DAY, ANTHONY J., 2017. The Good the Bad and the Ugly of Glycosaminoglycans in Tissue Engineering Applications PHARMACEUTICALS. 10(2),
AYERST, BETHANIE I., SMITH, RAYMOND A. A., NURCOMBE, VICTOR, DAY, ANTHONY J., MERRY, CATHERINE L. R. and COOL, SIMON M., 2017. Growth Differentiation Factor 5-Mediated Enhancement of Chondrocyte Phenotype Is Inhibited by Heparin: Implications for the Use of Heparin in the Clinic and in Tissue Engineering Applications TISSUE ENGINEERING PART A. 23(7-8), 275-292
WAN, SIMON, BORLAND, SAMANTHA, RICHARDSON, STEPHEN M., MERRY, CATHERINE L. R., SAIANI, ALBERTO and GOUGH, JULIE E., 2016. Self-assembling peptide hydrogel for intervertebral disc tissue engineering ACTA BIOMATERIALIA. 46, 29-40
DELIGNY, AUDREY, DIERKER, TABEA, DAGALV, ANDERS, LUNDEQUIST, ANDERS, ERIKSSON, INGER, NAIRN, ALISON V., MOREMEN, KELLEY W., MERRY, CATHERINE L. R. and KJELLEN, LENA, 2016. NDST2 (N-Deacetylase/N-Sulfotransferase-2) Enzyme Regulates Heparan Sulfate Chain Length JOURNAL OF BIOLOGICAL CHEMISTRY. 291(36), 18600-18607
PIJUAN-GALITÓ S, TAMM C, SCHUSTER J, SOBOL M, FORSBERG L, MERRY CL and ANNERÉN C, 2016. Human serum-derived protein removes the need for coating in defined human pluripotent stem cell culture. Nature communications. 7, 12170 HOLLEY RJ, TAI G, WILLIAMSON AJ, TAYLOR S, CAIN SA, RICHARDSON SM, MERRY CL, WHETTON AD, KIELTY CM and CANFIELD AE, 2015. Comparative quantification of the surfaceome of human multipotent mesenchymal progenitor cells. Stem cell reports. 4(3), 473-88 BANKA S, CAIN SA, CARIM S, DALY SB, URQUHART JE, ERDEM G, HARRIS J, BOTTOMLEY M, DONNAI D, KERR B, KINGSTON H, SUPERTI-FURGA A, UNGER S, ENNIS H, WORTHINGTON J, HERRICK AL, MERRY CL, YUE WW, KIELTY CM and NEWMAN WG, 2014. Leri's pleonosteosis, a congenital rheumatic disease, results from microduplication at 8q22.1 encompassing GDF6 and SDC2 and provides insight into systemic sclerosis pathogenesis. Annals of the rheumatic diseases. 74(6), 1249-56 HAWKINS K, KERAMARI M, SONCIN F, SEGAL JM, MOHAMET L, MIAZGA N, RITSON S, BOBOLA N, MERRY CL and WARD CM, 2014. Novel cell lines isolated from mouse embryonic stem cells exhibiting de novo methylation of the E-cadherin promoter. Stem cells (Dayton, Ohio). 32(11), 2869-79 HOLLEY RJ, SMITH RA, VAN DE WESTERLO EM, PICKFORD CE, MERRY CL and VAN KUPPEVELT TH, 2014. Use of flow cytometry for characterization and fractionation of cell populations based on their expression of heparan sulfate epitopes. Methods in molecular biology (Clifton, N.J.). 1229, 239-51 WATSON HA, HOLLEY RJ, LANGFORD-SMITH KJ, WILKINSON FL, VAN KUPPEVELT TH, WYNN RF, WRAITH JE, MERRY CL and BIGGER BW, 2014. Heparan sulfate inhibits hematopoietic stem and progenitor cell migration and engraftment in mucopolysaccharidosis I. The Journal of biological chemistry. 289(52), 36194-203 KEENAN TD, PICKFORD CE, HOLLEY RJ, CLARK SJ, LIN W, DOWSEY AW, MERRY CL, DAY AJ and BISHOP PN, 2014. Age-dependent changes in heparan sulfate in human Bruch's membrane: implications for age-related macular degeneration. Investigative ophthalmology & visual science. 55(8), 5370-9 GIANGRECO A and MERRY CL, 2014. The biochemical determinants of tissue regeneration. Biochemical Society transactions. 42(3), 607-8 SERGIJENKO A, LANGFORD-SMITH A, LIAO AY, PICKFORD CE, MCDERMOTT J, NOWINSKI G, LANGFORD-SMITH KJ, MERRY CL, JONES SA, WRAITH JE, WYNN RF, WILKINSON FL and BIGGER BW, 2013. Myeloid/Microglial driven autologous hematopoietic stem cell gene therapy corrects a neuronopathic lysosomal disease. Molecular therapy : the journal of the American Society of Gene Therapy. 21(10), 1938-49 BALDWIN AK, CAIN SA, LENNON R, GODWIN A, MERRY CL and KIELTY CM, 2013. Epithelial-mesenchymal status influences how cells deposit fibrillin microfibrils. Journal of cell science. 127(Pt 1), 158-71 LANGFORD-SMITH A, WILKINSON FL, LANGFORD-SMITH KJ, HOLLEY RJ, SERGIJENKO A, HOWE SJ, BENNETT WR, JONES SA, WRAITH J, MERRY CL, WYNN RF and BIGGER BW, 2012. Hematopoietic stem cell and gene therapy corrects primary neuropathology and behavior in mucopolysaccharidosis IIIA mice. Molecular therapy : the journal of the American Society of Gene Therapy. 20(8), 1610-21 WILKINSON FL, HOLLEY RJ, LANGFORD-SMITH KJ, BADRINATH S, LIAO A, LANGFORD-SMITH A, COOPER JD, JONES SA, WRAITH JE, WYNN RF, MERRY CL and BIGGER BW, 2012. Neuropathology in mouse models of mucopolysaccharidosis type I, IIIA and IIIB. PloS one. 7(4), e35787 MEADE KA, WHITE KJ, PICKFORD CE, HOLLEY RJ, MARSON A, TILLOTSON D, VAN KUPPEVELT TH, WHITTLE JD, DAY AJ and MERRY CL, 2012. Immobilization of heparan sulfate on electrospun meshes to support embryonic stem cell culture and differentiation. The Journal of biological chemistry. 288(8), 5530-8 SMITH RA, MEADE K, PICKFORD CE, HOLLEY RJ and MERRY CL, 2011. Glycosaminoglycans as regulators of stem cell differentiation. Biochemical Society transactions. 39(1), 383-7 HOLLEY RJ, DELIGNY A, WEI W, WATSON HA, NIÑONUEVO MR, DAGÄLV A, LEARY JA, BIGGER BW, KJELLÉN L and MERRY CL, 2011. Mucopolysaccharidosis type I, unique structure of accumulated heparan sulfate and increased N-sulfotransferase activity in mice lacking α-l-iduronidase. The Journal of biological chemistry. 286(43), 37515-24 PICKFORD CE, HOLLEY RJ, RUSHTON G, STAVRIDIS MP, WARD CM and MERRY CL, 2011. Specific glycosaminoglycans modulate neural specification of mouse embryonic stem cells. Stem cells (Dayton, Ohio). 29(4), 629-40 CLARK SJ, KEENAN TD, FIELDER HL, COLLINSON LJ, HOLLEY RJ, MERRY CL, VAN KUPPEVELT TH, DAY AJ and BISHOP PN, 2011. Mapping the differential distribution of glycosaminoglycans in the adult human retina, choroid, and sclera. Investigative ophthalmology & visual science. 52(9), 6511-21 HOLLEY RJ, PICKFORD CE, RUSHTON G, LACAUD G, GALLAGHER JT, KOUSKOFF V and MERRY CL, 2010. Influencing hematopoietic differentiation of mouse embryonic stem cells using soluble heparin and heparan sulfate saccharides. The Journal of biological chemistry. 286(8), 6241-52 THORNTON K, SMITH AM, MERRY CL and ULIJN RV, 2009. Controlling stiffness in nanostructured hydrogels produced by enzymatic dephosphorylation. Biochemical Society transactions. 37(Pt 4), 660-4 SONCIN F, MOHAMET L, ECKARDT D, RITSON S, EASTHAM AM, BOBOLA N, RUSSELL A, DAVIES S, KEMLER R, MERRY CL and WARD CM, 2009. Abrogation of E-cadherin-mediated cell-cell contact in mouse embryonic stem cells results in reversible LIF-independent self-renewal. Stem cells (Dayton, Ohio). 27(9), 2069-80 MERRY CL and WARD CM, 2008. A sugar rush for developmental biology. Development (Cambridge, England). 135(8), 1389-93 JOHNSON CE, CRAWFORD BE, STAVRIDIS M, TEN DAM G, WAT AL, RUSHTON G, WARD CM, WILSON V, VAN KUPPEVELT TH, ESKO JD, SMITH A, GALLAGHER JT and MERRY CL, 2007. Essential alterations of heparan sulfate during the differentiation of embryonic stem cells to Sox1-enhanced green fluorescent protein-expressing neural progenitor cells. Stem cells (Dayton, Ohio). 25(8), 1913-23 LAMANNA WC, KALUS I, PADVA M, BALDWIN RJ, MERRY CL and DIERKS T, 2007. The heparanome--the enigma of encoding and decoding heparan sulfate sulfation. Journal of biotechnology. 129(2), 290-307 EASTHAM AM, SPENCER H, SONCIN F, RITSON S, MERRY CL, STERN PL and WARD CM, 2007. Epithelial-mesenchymal transition events during human embryonic stem cell differentiation. Cancer research. 67(23), 11254-62 SPENCER HL, EASTHAM AM, MERRY CL, SOUTHGATE TD, PEREZ-CAMPO F, SONCIN F, RITSON S, KEMLER R, STERN PL and WARD CM, 2007. E-cadherin inhibits cell surface localization of the pro-migratory 5T4 oncofetal antigen in mouse embryonic stem cells. Molecular biology of the cell. 18(8), 2838-51 CLAMP A, BLACKHALL FH, HENRIOUD A, JAYSON GC, JAVAHERIAN K, ESKO J, GALLAGHER JT and MERRY CL, 2006. The morphogenic properties of oligomeric endostatin are dependent on cell surface heparan sulfate. The Journal of biological chemistry. 281(21), 14813-22 LAMANNA WC, BALDWIN RJ, PADVA M, KALUS I, TEN DAM G, VAN KUPPEVELT TH, GALLAGHER JT, VON FIGURA K, DIERKS T and MERRY CL, 2006. Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity. The Biochemical journal. 400(1), 63-73 MERRY AH and MERRY CL, 2005. Glycoscience finally comes of age. EMBO reports. 6(10), 900-3 TEN DAM GB, VAN DE WESTERLO EM, SMETSERS TF, WILLEMSE M, VAN MUIJEN GN, MERRY CL, GALLAGHER JT, KIM YS and VAN KUPPEVELT TH, 2004. Detection of 2-O-sulfated iduronate and N-acetylglucosamine units in heparan sulfate by an antibody selected against acharan sulfate (IdoA2S-GlcNAc)n. The Journal of biological chemistry. 279(37), 38346-52 MURPHY KJ, MERRY CL, LYON M, THOMPSON JE, ROBERTS IS and GALLAGHER JT, 2004. A new model for the domain structure of heparan sulfate based on the novel specificity of K5 lyase. The Journal of biological chemistry. 279(26), 27239-45 WILSON VA, GALLAGHER JT and MERRY CL, 2003. Heparan sulfate 2-O-sulfotransferase (Hs2st) and mouse development. Glycoconjugate journal. 19(4-5), 347-54 MERRY CL and GALLAGHER JT, 2003. New insights into heparan sulphate biosynthesis from the study of mutant mice. Biochemical Society symposium. 47-57
BLACKHALL FH, MERRY CL, LYON M, JAYSON GC, FOLKMAN J, JAVAHERIAN K and GALLAGHER JT, 2003. Binding of endostatin to endothelial heparan sulphate shows a differential requirement for specific sulphates. The Biochemical journal. 375(Pt 1), 131-9 MERRY CL and WILSON VA, 2002. Role of heparan sulfate-2-O-sulfotransferase in the mouse. Biochimica et biophysica acta. 1573(3), 319-27
BLACKHALL FH, MERRY CL, DAVIES EJ and JAYSON GC, 2001. Heparan sulfate proteoglycans and cancer. British journal of cancer. 85(8), 1094-8 MERRY CL, BULLOCK SL, SWAN DC, BACKEN AC, LYON M, BEDDINGTON RS, WILSON VA and GALLAGHER JT, 2001. The molecular phenotype of heparan sulfate in the Hs2st-/- mutant mouse. The Journal of biological chemistry. 276(38), 35429-34 MERRY CL, LYON M, DEAKIN JA, HOPWOOD JJ and GALLAGHER JT, 1999. Highly sensitive sequencing of the sulfated domains of heparan sulfate. The Journal of biological chemistry. 274(26), 18455-62