School of Pharmacy

Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

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HOSSAN MS, CHAN ZY, COLLINS HM, SHIPTON FN, BUTLER MS, RAHMATULLAH M, LEE JB, GERSHKOVICH P, KAGAN L, KHOO TJ, WIART C and BRADSHAW TD, 2019. Cardiac glycoside cerberin exerts anticancer activity through PI3K/AKT/mTOR signal transduction inhibition. Cancer letters. 453, 57-73

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LIU, ZHIMIN, TURYANSKA, LYUDMILA, ZAMBERLAN, FRANCESCO, PACIFICO, SALVATORE, BRADSHAW, TRACEY D, MORO, FABRIZIO, FAY, MICHAEL W, WILLIAMS, HUW and THOMAS, NEIL R, 2019. Synthesis of folic acid functionalized gold nanoclusters for targeting folate receptor-positive cells. Nanotechnology. 30, 505102

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A F BREEN, G WELLS, L TURYANSKA and T D BRADSHAW, 2019. Development of novel apoferritin formulations for antitumour benzothiazoles. Cancer Reports. 2, e1155

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KAOUTHAR BOUZINAB, HELEN SUMMERS, JIHONG ZHANG, MALCOLM F. G. STEVENS, CHRISTOPHER J. MOODY, LYUDMILA TURYANSKA, NEIL R. THOMAS, PAVEL GERSHKOVICH, MARIANNE B. ASHFORD, EMILY VITTERSO, LISA C. D. STORER, RICHARD GRUNDY and TRACEY D. BRADSHAW, 2019. In search of effective therapies to overcome resistance to Temozolomide in brain tumours Cancer Drug Resistance. 2,

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GARCES, AIMIE E., AL-HAYALI, MOHAMMED, LEE, JONG BONG, LI, JIAXIN, GERSHKOVICH, PAVEL, BRADSHAW, TRACEY D. and STOCKS, MICHAEL J., 2019. Codrug Approach for the Potential Treatment of EML4-ALK Positive Lung Cancer ACS Medicinal Chemistry Letters. acsmedchemlett.9b00378

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BOUZINAB, KAOUTHAR, THOMAS, NEIL R., TURYANSKA, LYUDMILA, GERSHKOVICH, PAVEL, WESTON, NICOLA, ASHFORD, MARIANNE B. and BRADSHAW, TRACEY D., 2019. TARGETING BRAIN TUMOURS: APOFERRITIN NANOCAGE FOR DELIVERY OF NOVEL ANALOGUES OF TEMOZOLOMIDE NEURO-ONCOLOGY. 21, 4-4

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JC QUILLES, FR ROCHCO, CA MONTANARI, A LEITAO, VW MIGNONE, MA ARRUDA, L TURYANSKA and TD BRADSHAW, 2019. Apoferritin-encapsulation of cysteine protease inhibitors for cathepsin L inhibition in cancer cells. RSC Advances. 9, 36699-36706

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ABID, MOHAMMED, NOUCH, RYAN, BRADSHAW, TRACEY D., LEWIS, WILLIAM and WOODWARD, SIMON, 2019. Tripodal O-N-O Bis-Phenolato Amine Titanium(IV) Complexes Show High in vitro Anti-Cancer Activity EUROPEAN JOURNAL OF INORGANIC CHEMISTRY. 2774-2780

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YANG, ZHIKUAN, WEI, DANPING, DAI, XIAOLI, STEVENS, MALCOLM F. G., BRADSHAW, TRACEY D., LUO, YING and ZHANG, JIHONG, 2019. C8-Substituted Imidazotetrazine Analogs Overcome Temozolomide Resistance by Inducing DNA Adducts and DNA Damage FRONTIERS IN ONCOLOGY. 9,

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TIM J. FYFE, BARRIE KELLAM, DAVID A. SYKES, BEN CAPUANO, PETER J. SCAMMELLS, J. ROBERT LANE, STEVEN J. CHARLTON and SHAILESH N. MISTRY, 2019. Structure-Kinetic Profiling of Haloperidol Analogues at the Human Dopamine D2 Receptor Journal of Medicinal Chemistry. 62(21), 9488-9520

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FYFE, TIM J., ZARZYCKA, BARBARA, LIM, HERMAN D., KELLAM, BARRIE, MISTRY, SHAILESH N., KATRICH, VSEVOLOD, SCAMMELLS, PETER J., LANE, J. ROBERT and CAPUANO, BEN, 2019. A Thieno[2,3-d]pyrimidine Scaffold Is a Novel Negative Allosteric Modulator of the Dopamine D-2 Receptor JOURNAL OF MEDICINAL CHEMISTRY. 62(1), 174-206

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FYFE, TIM J., KELLAM, BARRIE, SYKES, DAVID A., CAPUANO, BEN, SCAMMELLS, PETER J., LANE, J. ROBERT, CHARLTON, STEVEN J. and MISTRY, SHAILESH N., 2019. Structure-Kinetic Profiling of Haloperidol Analogues at the Human Dopamine D-2 Receptor JOURNAL OF MEDICINAL CHEMISTRY. 62(21), 9488-9520

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ADLERE, ILZE, CASPAR, BIRGIT, ARIMONT, MARTA, DEKKERS, SEBASTIAN, VISSER, KIRSTEN, STUIJT, JEFFREY, DE GRAAF, CHRIS, STOCKS, MICHAEL, KELLAM, BARRIE, BRIDDON, STEPHEN, WIJTMANS, MAIKEL, DE ESCH, IWAN, HILL, STEPHEN and LEURS, ROB, 2019. Modulators of CXCR4 and CXCR7/ACKR3 Function MOLECULAR PHARMACOLOGY. 96(6), 737-752

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LI C, VOOS KM, PATHAK M, HALL G, MCCRAE KR, DREVENY I, LI R and EMSLEY J, 2019. Plasma kallikrein structure reveals apple domain disc rotated conformation compared to factor XI. Journal of thrombosis and haemostasis : JTH. (In Press.)

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PATHAK M, MANNA R, LI C, KAIRA BG, HAMAD BK, BELVISO BD, BONTURI CR, DREVENY I, FISCHER PM, DEKKER LV, OLIVA MLV and EMSLEY J, 2019. Crystal structures of the recombinant β-factor XIIa protease with bound Thr-Arg and Pro-Arg substrate mimetics. Acta crystallographica. Section D, Structural biology. 75(Pt 6), 578-591
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School of Pharmacy

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