School of Pharmacy

Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

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PETRI A, KIM HJ, XU Y, DE GROOT R, LI C, VANDENBULCKE A, VANHOORELBEKE K, EMSLEY J and CRAWLEY JTB, 2019. Crystal structure and substrate-induced activation of ADAMTS13. Nature communications. 10(1), 3781

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MORGAN J, SALEEM M, NG R, ARMSTRONG C, WONG SS, CAULTON SG, FICKLING A, WILLIAMS HEL, MUNDAY AD, LÓPEZ JA, SEARLE MS and EMSLEY J, 2019. Structural basis of the leukocyte integrin Mac-1 I-domain interactions with the platelet glycoprotein Ib. Blood advances. 3(9), 1450-1459

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SCHMAIER AH, EMSLEY J, FEENER EP, GAILANI D, GOVERS-RIEMSLAG JWP, KAPLAN AP, MAAS C, MORRISSEY JH, RENNÉ T, SIDELMANN JJ and MEIJERS JCM, 2019. Nomenclature of factor XI and the contact system. Journal of thrombosis and haemostasis : JTH. (In Press.)

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KARDEBY C, FÄLKER K, HAINING EJ, CRIEL M, LINDKVIST M, BARROSO R, PÅHLSSON P, LJUNGBERG LU, TENGDELIUS M, RAINGER GE, WATSON S, EBLE JA, HOYLAERTS MF, EMSLEY J, KONRADSSON P, WATSON SP, SUN Y and GRENEGÅRD M, 2019. Synthetic glycopolymers and natural fucoidans cause human platelet aggregation via PEAR1 and GPIbα. Blood advances. 3(3), 275-287

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GARVIN AJ, KHALAF AHA, RETTINO A, XICLUNA J, BUTLER L, MORRIS JR, HEERY DM and CLARKE NM, 2019. GSK3β-SCFFBXW7α mediated phosphorylation and ubiquitination of IRF1 are required for its transcription-dependent turnover. Nucleic acids research. 47(9), 4476-4494

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PADROSA, DAVID ROURA, ALAUX, RAPHAEL, SMITH, PHILLIP, DREVENY, INGRID, LOPEZ-GALLEGO, FERNANDO and PARADISI, FRANCESCA, 2019. Enhancing PLP-Binding Capacity of Class-III omega-Transaminase by Single Residue Substitution FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY. 7,

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PATHAK, MONIKA, MANNA, ROSA, LI, CHAN, KAIRA, BUBACARR G., HAMAD, BADRALDIN KAREEM, BELVISO, BENNY DANILO, BONTURI, CAMILA R., DREVENY, INGRID, FISCHER, PETER M., DEKKER, LODEWIJK V., VILELA OLIVA, MARIA LUIZA and EMSLEY, JONAS, 2019. Crystal structures of the recombinant -factor XIIa protease with bound Thr-Arg and Pro-Arg substrate mimetics ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY. 75, 578-591

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TIM J. FYFE, BARRIE KELLAM, SHAILESH N. MISTRY, PETER J. SCAMMELLS, J. ROBERT LANE and BEN CAPUANO, 2019. Subtle modifications to a thieno[2,3-d]pyrimidine scaffold yield negative allosteric modulators and agonists of the dopamine D2 receptor European Journal of Medicinal Chemistry. 168, 474 - 490

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SHAILESH N. MISTRY, PASCAL MARCHAND and BARRIE KELLAM, 2019. 27th Annual GP2A Medicinal Chemistry Conference Pharmaceuticals. 12, 179

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ADLERE, ILZE, CASPAR, BIRGIT, ARIMONT, MARTA, DEKKERS, SEBASTIAN, VISSER, KIRSTEN, STUIJT, JEFFREY, DE GRAAF, CHRIS, STOCKS, MICHAEL, KELLAM, BARRIE, BRIDDON, STEPHEN, WIJTMANS, MAIKEL, DE ESCH, IWAN, HILL, STEPHEN and LEURS, ROB, 2019. Modulators of CXCR4 and CXCR7/ACKR3 function Molecular Pharmacology. mol.119.117663

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BOSQUILLON, C, PANDUGA, V and STOCKS, M J, 2019. Understanding the mechanisms controlling inhaled drug retention in the lungs using human bronchial epithelial cell layers In: BRITISH JOURNAL OF PHARMACOLOGY. 3009

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FENN, SAMUEL, DUBERN, JEAN-FREDERIC, STOCKS, MICHAEL, ELMSLEY, JONAS and CAMARA, MIGUEL, 2019. Identification of a nitrite reductase in Pseudomonas aeruginosa as a potential antimicrobial target Access Microbiology. 1(1A), 635

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ASHRAF S, RADHI M, GOWLER P, BURSTON JJ, GANDHI RD, THORN GJ, PICCININI AM, WALSH DA, CHAPMAN V and DE MOOR CH, 2019. The polyadenylation inhibitor cordycepin reduces pain, inflammation and joint pathology in rodent models of osteoarthritis. Scientific reports. 9(1), 4696

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JISOOK LEE, NATALIE B. VINH, NYSSA DRINKWATER, WEI YANG, KOMAGAL KANNAN SIVARAMAN, LUKE S. SCHEMBRI, MICHELLE GAZDIK, PETER M. GRIN, GEORGINA S. BUTLER, CHRISTOPHER M. OVERALL, SUSAN A. CHARMAN, SHEENA MCGOWAN* and PETER J. SCAMMELLS*, 2019. Novel Human Aminopeptidase N Inhibitors: Discovery and Optimization of Subsite Binding Interactions Journal of Medicinal Chemistry. 62(15), 7185-7209

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LUKE S. SCHEMBRI, JONAS ERIKSSON and LUKE R. ODELL*, 2019. Palladium(0)-Catalyzed Carbonylative Synthesis of N-Acylsulfonamides via Regioselective Acylation The Journal of Organic Chemistry. 84(11), 6970-6981
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School of Pharmacy

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