Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

Content: GENG, Y., VERHAMME, I. M., SUN, M. F., BAJAJ, S. P., EMSLEY, J. and GAILANI, D., 2013. Analysis of the factorXI variant Arg184Gly suggests a structural basis for factorIX binding to factorXIa JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 11(7), 1374-1384

Content: OTHMAN, MAHA, KAUR, HARMANPREET and EMSLEY, JONAS, 2013. Platelet-Type von Willebrand Disease: New Insights into the Molecular Pathophysiology of a Unique Platelet Defect SEMINARS IN THROMBOSIS AND HEMOSTASIS. 39(6), 663-673

Content: BAY-RICHTER, C., O'CALLAGHAN, M.J., MATHUR, N., O'TUATHAIGH, C.M.P., HEERY, D.M., FONE, K.C.F, WADDINGTON, J.L. and MORAN, P.M., 2013. D-amphetamine and antipsychotic drug effects on latent inhibition in mice lacking dopamine D₂ receptors Neuropsychopharmacology. 38(8), 1512-1520

Content: SHAO, HAO, SHI, SHENHUA, HUANG, SHILIANG, HOLE, ALISON, ABBAS, ABDULLAHI Y., BAUMLI, SONJA, LIU, XIANGRUI, LAM, FRANKIE, FOLEY, DAVID W., FISCHER, PETER M., NOBLE, MARTIN, ENDICOTT, JANE A., PEPPER, CHRIS and WANG, SHUDONG, 2013. Substituted 4-(thiazol-5-yl)-2-(phenylamino)pyrimidines are highly active CDK9 inhibitors: synthesis, x-ray crystal structure, SAR and anti-cancer activities: Journal of Medicinal Chemistry Journal of Medicinal Chemistry. 56, 640-659

Content: MORENO, J.A., HALLIDAY, M., MOLLOY, C., RADFORD, H., VERITY, N., AXTEN, J.M., ORTORI, C.A., WILLIS, A.E., FISCHER, P.M., BARRETT, D.A. and MALLUCCI, G.R., 2013. Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice: Science Translational Medicine Science Translational Medicine. 5(206), 206ra138

Content: MARYATI M, KAUR I, JADHAV GP, OLOTU-UMOREN L, OVEH B, HASHMI L, FISCHER PM and WINKLER GS, 2013. A fluorescence-based assay suitable for quantitative analysis of deadenylase enzyme activity. Nucleic acids research. (In Press.)

Content: SHAO H, SHI S, FOLEY DW, LAM F, ABBAS AY, LIU X, HUANG S, JIANG X, BAHARIN N, FISCHER PM and WANG S, 2013. Synthesis, structure-activity relationship and biological evaluation of 2,4,5-trisubstituted pyrimidine CDK inhibitors as potential anti-tumour agents. European journal of medicinal chemistry. 70, 447-55

Content: MYRVANG, H.K., GUO, X., LI, C. and DEKKER, L.V., 2013. Protein interactions between surface annexin A2 and S100A10 mediate adhesion of breast cancer cells to microvascular endothelial cells FEBS Letters. 587(19), 3210-3215

Content: ECCLES ET AL, 2013. Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer Breast Cancer research. 15(5), R92

Content: WAHLE E and WINKLER GS, 2013. RNA decay machines: deadenylation by the Ccr4-not and Pan2-Pan3 complexes. Biochimica et biophysica acta. 1829(6-7), 561-70

Content: MARYATI, M., KAUR, I., JADHAV,G.P., OLOTU-UMOREN, L., OVEH, B., HASHMI, L., FISCHER, P.M. and WINKLER, G.S., 2013. A fluorescence-based assay suitable for quantitative analysis of deadenylase enzyme activity Nucleic Acids Research. n/a(n/a), n/a

Content: WINKLER GS and BALACCO DL, 2013. Heterogeneity and complexity within the nuclease module of the Ccr4-Not complex. Frontiers in genetics. 4, 296

Content: RENGACHARI S, ASCHAUER P, SCHITTMAYER M, MAYER N, GRUBER K, BREINBAUER R, BIRNER-GRUENBERGER R, DREVENY I and OBERER M, 2013. Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase. The Journal of Biological Chemistry. 288(43), 31093-104

Content: MISTRY, SHAILESH N, VALANT, CELINE, SEXTON, PATRICK M, CAPUANO, BEN, CHRISTOPOULOS, ARTHUR and SCAMMELLS, PETER J, 2013. Synthesis and pharmacological profiling of analogues of benzyl quinolone carboxylic acid (BQCA) as allosteric modulators of the M₁ muscarinic receptor Journal of Medicinal Chemistry. 56(12), 5151-5172

Content: MISTRY, SHAILESH N, BAKER, JILLIAN G, FISCHER, PETER M, HILL, STEPHEN J, GARDINER, SHEILA M and KELLAM, BARRIE, 2013. Synthesis and in vitro and in vivo characterization of highly β₁-selective β-adrenoceptor partial agonists Journal of Medicinal Chemistry. 56(10), 3852-3865

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