Biodiscovery Institute Publications

All BDI principal investigators (past and recent) on each publication are highlighted in bold. The same publications appear under each PI that is an author on it.

Cinzia Allegrucci

• Pal, A., Ashworth, J.C., Collier, P., Probert, C., Jones S, Leza, E.P., Meakin, M.L., A Ritchie, A., Onion, D., Clarke, P.A., Allegrucci C., Grabowska, A.M. (2020). 'A 3D Heterotypic Breast Cancer Model Demonstrates a Role for Mesenchymal Stem Cells in Driving a Proliferative and Invasive Phenotype', Cancers, 12, 2290.
• Simpson, S., Dunning ,M., de Brot, S., Alibhai, A., Bailey, C., Woodcock, C.L., Mestas, M., Akhtar, S., Jeyapalan, J.N., Lothion-Roy, J., Emes, R.D., Allegrucci, C., Rizvanov, A.A., Mongan, N.P., Rutland, C.S. (2020). 'Molecular Characterisation of Canine Osteosarcoma in High Risk Breeds', Cancers, 12, 2405.
• Shaimardanova, A.A., Chulpanova, D.S., Solovyeva, V.V., Mullagulova, A.I., Kitaeva, K.V., Allegrucci, C., Rizvanov, A.A. (2020). 'Metachromatic Leukodystrophy: Diagnosis, Modeling, and Treatment Approaches'. Front Med.,7, 576221.

Kenton Arkill

• Gyarmati, Shroff, Riquier-Brison, Kriz, Kaissling, Neal, Arkill, Nariman Ahmadi, Gill, Moon, Desposito, Peti-Peterdi (2021) ‘A new view of macula densa cell microanatomy’ Am J Physio-Renal 320(3), F492-F504.
• Nizamudeen, E-R Xu, Karthik, Halawa, Arkill, Jackson, Bates, Emsley (2021) ‘Structural assessment of SARS-cov2 accessory protein ORF7a predicts LFA-1 and Mac-1 binding potential’ Bioscience Reports BSR 41(1) 20203837.
• Jaradat, Macedo, Sousa, Arkill, Alexander, Aylott, Sarmento (2020) ‘Prediction of the enhanced insulin absorption across a triple co-cultured intestinal model using mucus penetrating PLGA nanoparticles’ International Journal of Pharmaceutics 585, 119516.
• Allen, Malhi, Whatmore, Bates, Arkill (2020) ‘Non-invasive measurement of retinal permeability in a diabetic rat model’ Microcirculation 00:e12623.
• Dalwadi, King, Dyson, Arkill (2020) ‘A mathematical model to determine the effect of a sub-glycocalyx space’ Physics Review Fluids 5, 043103.
• Owen-Woods, Joulia, Barkaway, Rolas, Ma, Nottebaum, Arkill, Stein, Girbl, Golding, Bates,  Vestweber, Voisin, Nourshargh (2020) ‘Local microvascular leakage promotes trafficking of activated neutrophils to remote organs in vivo’ Journal of Clinical Investigation 130(5):2301-2318 : Winner of EVBO publication highlight competition, October 2020.
• Ashworth, Thompson, James, Slater, Pijuan-Galito, Lis-Slimak, Holley, Meade, Thompson, Arkill, Tassieri, Wright, Farnie, Merry (2020) ‘Peptide Gels of Fully-Defined Composition and Mechanics for Probing Cell-Cell and Cell-Matrix Interactions In Vitro’ Matrix Biology (85-86): 15-33.

David Bates

• ZA Nizamudeen, ER Xu, V Karthik, M Halawa, KP Arkill, A Jackson, DO Bates, J Emsley. Structural assessment of SARS-cov2 accessory protein ORF7a predicts LFA-1 and Mac-1 binding potential. Biosci Rep. 2020 Dec 11: BSR20203837. DOI: 10.1042/BSR20203837.
• B Boonsri, K Yacqub-Usman, P Thintharua, KZ Myint, T Sae-Lao, P Collier, C Suriyonplengsaeng, N Lapcharoensap, B Balasubramanian, S Venkatraman, IU. Egbuniwe, D Gomez, T Janvilisri, A Zaitoun, R Tohtong, AM Grabowska, S Kumkate, DO Bates, K Wongprasert, Effect of combining EGFR tyrosine kinase inhibitors and cytotoxic agents on cholangiocarcinoma cells. Cancer Research and Treatment 2021 Apr;53(2):457-470.
• TJ Makhafola, M Mbele, K Yacqub-Usman, A Hendren, DB Haigh, Z Blackley, M Meyer, NP Mongan, DO Bates and Z Dlamini Apoptosis in Cancer Cells is Induced by Alternative Splicing of hnrnpa2/B1 Through Splicing of Bcl-x, a Mechanism that can be Stimulated by an Extract of the South African Medicinal Plant, Cotyledon orbiculata. Frontiers in Oncology 2020, Oct 8;10:547392
• ZL Grant, L Whitehead, V Wong, Z He, R Yan, A Miles, AV Benest, DO Bates, Prahst C, K Bentley, BV Bui, RA Symons, L Coultas. Blocking endothelial apoptosis revascularizes the retina in a model of ischemic retinopathy. J Clin Invest 2020 Aug 3;130(8):4235-4251. 10.1172/JCI127668
• CL Allen, NK Malhi, JD Whatmore, DO Bates, KP Arkill Non-invasive measurement of retinal permeability in a diabetic rat model. Microcirculation 2020, 27 (6), e12623.
• C Owen-Woods, R Joulia, A Barkaway, L Rolas, B Ma, A Fee Nottebaum, KP Arkill, M Stein, T Girbl, M Golding, DO Bates, D Vestweber, MB Voisin, S Nourshargh. Local microvascular leakage promotes trafficking of activated neutrophils to remote organs in vivo. 2020 J Clin Invest. 130(5):2301-2318.
• D Wilson, E Jarman, R Mellin, M Wilson, S Waddell, P Tsokkou, N Younger, A Raven, S Bhalla, A Noll, SO Damink, F Schaap, P Chen, DO Bates, J Banales, C Dean, D Henderson, O Sansom, T Kendall, and L Boulter. Non-canonical Wnt signalling regulates scarring in biliary disease via the planar cell polarity receptors. Nature Comms. 2020, Jan 23;11(1):445.
• Ketelaar ME, Portelli MA, Dijk FN, Shrine N, Faiz A, Vermeulen CJ, Xu CJ, Hankinson J, Bhaker S, Henry AP, Billington CK, Shaw DE, Johnson SR, Benest AV, Pang V, Bates DO, Pogson ZEK, Fogarty A, mckeever TM, Singapuri A, Heaney LG, Mansur AH, Chaudhuri R, Thomson NC, Holloway JW, Lockett GA, Howarth PH, Niven R, Simpson A, Tobin MD, Hall IP, Wain LV, Blakey JD, Brightling CE, Obeidat M, Sin DD, Nickle DC, Bossé Y, Vonk JM, van den Berge M, Koppelman GH, Sayers I, Nawijn MC. Phenotypic and functional translation of IL33 genetics in asthma. (2021) J Asthma Clin immuniogy 147(1):144-157. DOI: 10.1016/j.jaci.2020.04.051.
• HULL, R., MBELE, M., MAKHAFOLA, T., HICKS, C., WANG, S. M., REIS, R. M., MEHROTRA, R., MKHIZE-KWITSHANA, Z., HUSSAIN, S., KIBIKI, G., BATES, D. O. And DLAMINI, Z., 2020. A multinational review: Oesophageal cancer in low to middle-income countries: Oncol Lett Oncol Lett. 20(4), 42.
• HULL, R., MBELE, M., MAKHAFOLA, T., HICKS, C., WANG, S. M., REIS, R. M., MEHROTRA, R., MKHIZE-KWITSHANA, Z., KIBIKI, G., BATES, D. O. And DLAMINI, Z., 2020. Cervical cancer in low and middle-income countries: Oncol Lett Oncol Lett. 20(3), 2058-2074.

Andrew Benest

• Chamorro-Jorganes A , Sweaad W , Katare R , Besnier M , Anwar M , Beazley - Long N, Sala-Newby G , Ruiz-Polo I , Chandrasekera D ,Ritchie A , Benest AV, Emanueli C. (2021).  METTL3 regulates angiogenesis by modulating let-7e-5p and mirna-18a-5p expression in endothelial cells, ATVB, 2021 In press
• Sezin AA, Hazan-Halevy,  Chamorro-Jorganes A,Meir Goldsmith M, Beazley-Long N, Sahoo S,  Sweaad W,Catapano F,  Ozaki-Tan S ,Angelini GD1, Paolo Madeddu P, Peer, Benest AV , Costanza Emanueli (2021) Bioinspired artificial exosomes based on lipid nanoparticles carrying let-7b-5p promote angiogenesis in vitro and in vivo. Mol Ther, 2021, 29(7), 2239-2252
• Thompson JL, Velasco ADR, Cardall A, Tarbox R, Richardson J, Clarke G, Lister M, Howson-Wells HC, Fleming VM, Khak M, Sloan T, Duckworth N, Denning , mccluare PM, Benest AV, Seedhouse CH (2021).  Comparative effects of viral transport medium heat inactivation upon downstream SARS-cov-2 detection in patient samples.  In press. 
• Ketelaar ME, Portelli MA, Dijk FN, Shrine N, Faiz A, Vermeulen CJ, Xu CJ, Hankinson J, Bhaker S, Henry AP, Billington CK, Shaw DE, Johnson SR, Benest AV, Pang V, Bates DO, Pogson ZEK, Fogarty A, mckeever TM, Singapuri A, Heaney LG, Mansur AH, Chaudhuri R, Thomson NC, Holloway JW, Lockett GA, Howarth PH, Niven R, Simpson A, Tobin MD, Hall IP, Wain LV, Blakey JD, Brightling CE, Obeidat M, Sin DD, Nickle DC, Bossé Y, Vonk JM, van den Berge M, Koppelman GH, Sayers I, Nawijn MC. Phenotypic and functional translation of IL33 genetics in asthma. (2021) J Asthma Clin immuniogy 147(1):144-157
• Grant ZL, Whitehead L, Wong VH, He Z, Yan RY, Miles AR, Benest AV, Bates DO, Prahst C, Bentley K, Bui BV, Symons RC, Coultas L.  Ischemic retina revascularisation by ‘vessel reassembly’ following endothelial apoptosis blockade. (2020) J Clin Invest, 130 (8): 4235-4251.
• Beazley Long N, Green K, Benest AV.  Quantification of pathological angiogenesis using laser induced choroidal neovascularisation. (2021) Methods in Molecular Biology, accepted
• Beazley Long N, Tabrizi Z, Green K, Benest AV.  In vitro technique to study glycolysis in cultured endothelial cells.  (2021) Methods in Molecular Biology accepted
• Horder JL, Pinel GD, Mongan NP, Benest AV.  Identification of novel candidate lymphangiogenesis regulators by unsupervised clustering of rnaseq data. Methods in Molecular Biology, 2021, accepted

Tracey Bradshaw

• The antitumor activity of 2-(4-Amino-3-methylphenyl)-5-fluorobenzothiazole (5F 203) in human gastric cancer models is mediated by arylhydrocarbon receptor (ahr) signaling. Yuling Wang, Ying Liu, Tao Tang, Ying Luo, Malcolm F.G. Stevens, Xi Cheng, Yan Yang, Dongfang Shi, Jihong Zhang, Tracey D. Bradshaw. J Cell Mol Med. 2020, 24 (2), 1750-1759 doi.org/10.1111/jcmm.14869.
• Delivery of temozolomide and N3-propargyl analog to brain tumors using an apoferritin nanocage. K. Bouzinab, H. Summers, M.F.G. Stevens, C.J. Moody, N.R. Thomas, P. Gershkovich, N. Weston, M.B. Ashford, T.D. Bradshaw, L. Turyanska . Appl Mater Interfaces 12(11),12609-12617 2020 DOI: 10.1021/acsami.0c01514.
• Modulation of the acidity of the 8-carboxamide group in the temozolomide family of antitumor imidazo[5,1-d][1,2,3,5]tetrazines. HS Summers, MB Foreiter, W Lewis, CJ Moody, TD Bradshaw, and MFG Stevens. Arkivoc 2020 part VII 36-45.
• New treatments in renal cancer: The ahr ligands. B Itkin, A Breen, L Turyanska, EO Sandes, TD Bradshaw, AI Loaiza-Perez. Int. J. Mol. Sci. 21 (10) 3551, 2020. DOI: 10.3390/ijms21103551
• The natural alkaloid Jerantinine B has activity in acute myeloid leukemia cells through a mechanism involving c-Jun
• HM Alhuthali, TD Bradshaw, K-H Lim, T-S Kam and CH Seedhouse. BMC Cancer 2020 20:629.Doi.org/10.1186/S12885-020-07119-2.
• Structure-based design of highly selective 2,4,5-trisubstituted pyrimidine CDK9 inhibitors as anti-cancer agents. Hao Shao; David W. Foley; Shiliang Huang; Abdullahi Y. Abbas; Frankie Lam; Pavel Gershkovich; Tracey D. Bradshaw; Chris Pepper; Peter M. Fischer. Eur J Med Chem 2021. DOI: 10.1016/j.ejmech.2021.113244
• Novel semi-synthetic Cu (II)-cardamonin complex exerts potent anticancer activity against triple negative breast and pancreatic cancer cells via inhibition of the Akt signaling pathway. Md Shahadat Hossan, Mohammed Khaled Bin Break, Tracey D Bradshaw, Hilary M Collins, Christophe Wiart, Teng-Jin Khoo, Ahmed Alafnan. Molecules 2021. 26,2166. Https://doi.org/10.3390/molecules26082166

Lee Buttery

• Kirkham, G., Ware, J., Upton, T., Allen, S., Shakesheff, K., Buttery, L. (2020). Localized induction of gene expression in embryonic stem cell aggregates using holographic optical tweezers to create biochemical gradients. Regen Eng and Transl Med., 6, 251-261
• Babatunde O. Okesola, Shilei Ni, Burak Derkus, Carles C. Galeano, Abshar Hasan, Yuanhao Wu, Jopeth Ramis, Lee Buttery, Jonathan I. Dawson, Matteo D'Este, Richard O. C. Oreffo, David Eglin, Hongchen Sun, Alvaro Mata. (2020). Growth‐Factor Free Multicomponent Nanocomposite Hydrogels That Stimulate Bone Formation. Advanced Functional Materials, 30(14), https://doi.org/10.1002/adfm.201906205.

Miguel Cámara

• Vesty, E. F., Whitbread, A. L., Needs, S., Tanko, W., Jones, K., Halliday, N., Fatemeh Ghaderiardakani, F, Liu, X., Cámara, M. And Coates, J. (2020). 'Cross-kingdom signalling regulates spore germination in the moss Physcomitrella patens', Sci. Reports, 10:2614. DOI: 10.1038/s41598-020-59467-5
• Soukarieh, F., Liu, R., Romero, M., Roberston, SN., Richardson, W., Lucanto, S., Vico Oton. EW., Qudus, NR., Mashabi, A., Grossman, S., Ali, S., Sou, T., Kukavica-Ibrulj, I.,  Levesque, RC, Bergström, CAS., Halliday, N,, Mistry, SN., Emsley, J., Heeb, S., Williams, P., Cámara, M. And Stocks, MJ. (2020) 'Hit Identification of New Potent pqsr Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa', Frontiers in Chemistry, May 4;8:204. DOI: 10.3389/fchem.2020.00204. DOI: 10.3389/fchem.2020.00204
• Alcalde-Rico, M. , Olivares-Pacheco, J. , Halliday, N. , Cámara, M.  And Martínez, JL. (2020). 'The impaired quorum sensing response of Pseudomonas aeruginosa mexab-oprm efflux pump overexpressing mutants is not due to non-physiological efflux of 3-oxo-C12-HSL', Env. Microbiol. Dec;22(12):5167-5188. DOI: 10.1111/1462-2920.15177.
• Reina, JC., Romero, M., Salto, R., Cámara, M. And Llamas, I. (2021) 'ahap, a Quorum Quenching acylase from Psychrobacter sp. M9-54-1 that Attenuates Pseudomonas aeruginosa and Vibrio coralliilyticus virulence', Marine Drugs   2021 Jan 1;19(1):16. DOI: 10.3390/md19010016.
• Huertas-Rosales, O., Romero, M., Chan, KG., Hong, KW., Cámara, M., Heeb, S., Barrientos-Moreno, L., Molina-Henares., MA., Travieso, ML., Ramos-González, MI. And Espinosa-Urgel, M. (2021) 'Genome-wide analysis of targets for post-transcriptional regulation by Rsm proteins in Pseudomonas putida', Frontiers in Molecular Bioscience DOI. 2021 Feb 22;8:624061. DOI: 10.3389/fmolb.2021.624061.
• Fenn, S.,   Dubern, JF., Cigana, C.,  De Simone, M,  Lazenby, J., Juhas, M.,  Schwager, S., Bianconi, I., Döring, G.,  Elmsley, J., ,Eberl, L., Williams, P., Bragonzi, A., and  Cámara, M. (2021) 'nira is an alternative nitrite reductase from Pseudomonas aeruginosa with potential as an antivirulence target' mbio DOI. 10.1128/mbio.00207-21.

Weng Chan

• Blower, I., Tong, C., Sun, X., Murray, E., Luckett, J., Chan, W.C., Williams, P. And Hill, P.J. (2020). 'Gaussia luciferase as a reporter for quorum sensing in Staphylococcus aureus', Sensors, 20(15), 4305.

Yan Chen

• Chen, Y., James, J., Cornford, E., Jenkins. J. (2020). 'Relationship Between Mammography Readers Real-Life Performance and Performance In A Test-Set Based Assessment Scheme In A National Breast Screening Programme'. Radiology: Imaging Cancer, 2(5).

Beth Coyle

• Nasir,A.,  Cardall,A., Othman,R.T., Nicolaou,N., Lourdusamy, A., Linke,F., Onion,D., Ryzhova,M., Cameron,H., Valente,C., Ritchie,A., Korshunov,A., Pfister,S.M. Grabowska,A.M., Kerr,I.D., and Coyle,B., (2021) 'ABCB1 inhibition provides a novel therapeutic target to block TWIST1 induced migration in medulloblastoma', Neuro-Oncology Advances (in press)
• Roper, S.J., Linke, F., Scotting, P.J. and Coyle,B., (2021). '3D spheroid models of paediatric SHH medulloblastoma mimic tumour biology, drug response and metastatic dissemination'. Sci Rep 11, 4259  https://doi.org/10.1038/s41598-021-83809-6
• Taylor L, Kerr ID, Coyle B. (2021) 'Y-Box Binding Protein-1: A Neglected Target in Pediatric Brain Tumors?' Mol Cancer Res.  19, 375-387; DOI: 10.1158/1541-7786.MCR-20-0655              
• Linke F, Aldighieri M, Lourdusamy A, Grabowska AM, Stolnik S, Kerr ID, Merry CL, Coyle B. (2021) '3D hydrogels reveal medulloblastoma subgroup differences and identify extracellular matrix subtypes that predict patient outcome'. J Pathol.  Mar;253(3):326-338. DOI: 10.1002/path.5591. Epub 2020 Dec 17. PMID: 33206391.
• Chemosensitization of Temozolomide-Resistant Pediatric Diffuse Midline Glioma Using Potent Nanoencapsulated Forms of a N(3)-Propargyl Analogue, Vahid Heravi Shargh, Jeni Luckett, Kaouthar Bouzinab, Stephen Paisey, Lyudmila Turyanska, William G. B. Singleton, Stephen Lowis, Pavel Gershkovich, Tracey D. Bradshaw, Malcolm F. G. Stevens, Alison Bienemann, and Beth Coyle, ACS Appl. Mater. Interfaces 2021, 13, 30, 35266–35280.

Madhumita Dandapani

• Madni,M., Dandapani, M., Genetic syndromes predisposing to paediatric brain tumours. Paediatrics and Child Health, 30(3), 98-101.

Lodewijk Dekker

• Moreira, B.P., Armstrong, T., Batista, I.C.A., Clemente Tavares, N., Pire, C.V., de Moraes Mourão, M., Falcone, F.H., Dekker, L.V. (2020). Use of BODIPY-Labeled ATP Analogues in the Development and Validation of a Fluorescence Polarization-Based Assay for Screening of Kinase Inhibitors, ACS Omega, 5, 9064-9070. DOI: 10.1021/acsomega.9b03344.

Chris Denning

• Anika E. Knaust, Friederike Cuello, Umber Saleem, Malte Loos, Diogo Mosqueira, Sandra Laufer, Michaela Schweizer, Petra van der Kraak, Frederik Flenner, Bärbel M. Ulmer, Ingke Braren, Xiaoke Yin, Konstantinos Theofilatos, Birgit Klampe, Thomas Schulze, Yigal Pinto, Aryan Vink, Sian Harding, Manuel Mayr, Chris Denning, Thomas Eschenhagen, Arne Hansen. Reversal of mitochondria-associated membrane microdomain dysfunction in human cardiomyocytes with phospholamban p.Arg14del mutation by Ca2+ scavenging. EMBO Journal. In Press
• Jia R, Knight H, Blake H, Corner J, Denning C, Ball J, Bolton K, Morling JR, Coupland C, Figueredo G, Morris DE, Tighe P, Villalon A, Ayling K, Vedhara K. Experiences of the COVID-19 pandemic: cross-sectional analysis of risk perceptions and mental health in a student cohort. Journal of Psychosomatic Research. In Press
• Blake H, Knight H, Jia R, Corner J, Morling JR, Denning C, Ball JK, Bolton K, Figeuredo G, Morris D, Tighe P, Villalon A, Ayling K, Vedhara K. Students’ views towards SARS-cov-2 mass asymptomatic testing, social distancing and self-isolation in a university setting during the COVID-19 pandemic: a qualitative study. Https://www.preprints.org/manuscript/202101.0399/v1
• Goulding J, Kondrashov A, Denning C, Briddon S, White C, Hill S. The use of fluorescence correlation spectroscopy to monitor cell surface β2-adrenoceptors at low expression levels in human embryonic stem cell-derived cardiomyocytes and fibroblasts. The FASEB Journal In press
• Hall C, Gehmlich K, Denning C, Pavlovic D. Complex Relationship Between Cardiac Fibroblasts and Cardiomyocytes in Health and Disease. Journal of the American Heart Association. E019338. DOI: 10.1161/JAHA.120.019338. Online ahead of print.
• Nasir A, Thorpe J, Burroughs L,  Meurs J,  Pijuan-Galito S,  Irvine DJ,  Alexander MR,  Denning C. Discovery of a Novel Polymer for Xeno-free, Long-term Culture of Human Pluripotent Stem Cell Expansion. Advanced Healthcare Materials. E2001448. DOI: 10.1002/adhm.202001448. Online ahead of print
• Thompson JL, Velasco ADR, Lister M, Cardall A, Howson-Wells HC, Tarbox R, Richardson J, Clarke G, Fleming VM, Khakh M, Sloan T, Duckworth N, Walsh S, Denning C, mcclure CP, Benest AV, Seedhouse CH. Comparative effects of viral transport medium heat inactivation upon downstream SARS-cov-2 detection in patient samples. Journal of Medical Microbiology. In Press.
• Kondrashov A; Mohd Yusof NAN; Hasan A; Goulding J; Kodagoda T; Minh DH; Thi NV; Melarangi T; Dolatshad N; Gorelik J; Hill S; Harding S; Denning C. CRISPR/Cas9 mediated generation and analysis of N-terminal polymorphisms models of beta2-adrenoreceptor in isogenic hpsc-CM. Mol Ther – Method & Clinical Dev. 20:39-53, 2020. PMID: 33335946
• Thorpe J, Nasir A,  Burroughs L,  Meurs J,  Pijuan-Galito S,  Irvine DJ,  Alexander MR,  Denning C.  Discovery of a Novel Polymer for Xeno-free, Long-term Culture of hpsc Expansion. Biorxiv. Sept 2020. DOI: https://doi.org/10.1101/2020.09.16.298810
• Mannhardt I, Saleem U, Mosquiera DS, Lemoine M, Prondzynski M, Denning C, Hansen A, Eschenhagen T. Comparison of 10 control hpsc lines for drug screening in an engineered heart tissue format. Stem Cell Reports. 15(4):983-998, 2020
• Thompson JL, Velasco ADR, Cardall A. Tarbox R, Richardson J, Clarke G, Lister M, Howson-Wells HC, Fleming VM, Khakh M, Sloan T, Duckworth N, Walsh S, Denning C, mcclure CP, Benest AV, Seedhouse CH. Comparative effects of viral transport medium heat inactivation upon downstream SARS-cov-2 detection in patient samples. Medrvix preprint. DOI: 10.1101/2020.07.30.20164988 www.medrxiv.org/content/10.1101/2020.07.30.20164988v1
• Bodbin SE, Denning C, Mosqueira D. Transfection of hipsc-cardiomyocytes using Viafect™ Transfection Reagent. Methods & Protocols. 3(3):57, 2020
• Kargaran PK, Evans JM, Bodbin SE, Smith JGW, Nelson TJ, Denning C, Mosqueira D. Mitochondrial DNA: hotspot for potential gene modifiers regulating hypertrophic cardiomyopathy. Journal of Clinical Medicine, Cardiology. 9(8):2349, 2020
• Bhagwan JR, Mosqueira D, Chairez-Cantu K, Mannhardt I, Bodbin SE, Bakar M, Smith JGW, Denning C. Isogenic models of hypertrophic cardiomyopathy unveil differential phenotypes and mechanism-driven therapeutics. J Mol Cell Cardiol. 145:43-53, 2020.
• Saleem U, van Meer BJ, Katili PA, Mohd Yusof NAN, Mannhardt I, Garcia AK, Tertoolen L, de Korte T, Vlaming MLH, mcglynn K, Nebel J, Bahinski A, Harris K, Rossman E, Xu X, Burton FL, Smith GL, Clements P, Mummery CL, Eschenhagen T, Hansen A, Denning C. Blinded, multi-centre evaluation of drug-induced changes in contractility using hipsc-cms. Toxicol Sci. 176(1):103-123, 2020
• De Korte T, van Meer B, Garcia AK, Tertoolen L, Clements PJ, Bahinski A, Rossman EI, Xu X, Turner S, Denning C, Vlaming M, Braam S, Mummery C. Simultaneous measurement of contraction, voltage and calcium in HIPSC-CMS for the detection of inotropic effects under blinded conditions. J Pharmacol Toxicol Methods. 2019 Sep - Oct;99:106595
• Saleem U, Braren I, Mannhardt I, Denning C, Eschenhagen T, Hansen A. Force and calcium transients analysis in human engineered heart tissues reveals positive force-frequency relation at physiological frequency. Stem Cell Reports. 14:312-324, 2020.
• Bhagwan JR, Collins E, Mosqueira D, Bakar M, Johnson BB, Thompson A, Smith JGW, Denning C. Variable expression and silencing of CRISPR-Cas9 targeted transgenes identifies the AAVS1 locus as not an entirely safe harbour. F1000Res. 8:1911, 2020 DOI: 10.12688/f1000research.19894.2.
• Abakir A, Giles T, Cristini A, Foster JM, Dai N, Starczak M, Rubio-Roldan A, Eleftheriou M, Crutchley J, Flatt L, Young L, Gaffney D, Denning C, Emes R, Gackowski D, Corrêa Jr. IR, Garcia-Perez JL, Gromak N and Ruzov A. N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells. Nature Genetics. 2020 Jan;52(1):48-55.
• De Korte T, Katili PA, Mohd Yusof NAN, van Meer BJ, Saleem U, Burton FL, Smith GL, Clements P, Mummery CL, Eschenhagen T, Hansen A, Denning C. Unlocking Personalized Biomedicine and Drug Discovery with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Fit for Purpose or Forever Elusive? Annu Rev Pharmacol Toxicol. 60:529-551, 2020

James Dixon

• Enhanced Cellular Transduction of Nanoparticles Resistant to Rapidly Forming Plasma Protein Coronas. Lia A. Blokpoel Ferreras, Daniel Scott, Saul Vazquez Reina, Paul Roach, Teobaldo E. Torres, Gerardo F. Goya, Kevin M. Shakesheff, James E. Dixon (2020). Advanced Biosystems. 2000162.
• Rapidly Transducing and Spatially Localized Magnetofection Using Peptide-Mediated Non-Viral Gene Delivery Based on Iron Oxide Nanoparticles (2021), Blokpoel Ferreras, L. A., Chan, S. Y., Vazquez Reina, S., & Dixon, J. E. ACS Applied Nano Materials, 4(1), 167-181. Https://doi.org/10.1021/acsanm.0c02465.
• Alison Ritchie, Phil Clarke, James Dixon, Anna Grabowska (2020). The Jacket with Pulling Power-a novel approach to early stage evaluation of magnetic nanoparticles  Animal Technology & Welfare, Vol 19 No. 2, 166-168.
• Hosam Al-Deen M.Abu Awwad, Lalitha Thiagarajan, Janos M.Kanczler, Mahetab H.Amer, Gordon Bruce, Stuart Lanham, Robin M.H.Rumney, Richard O.C.Oreffo, James E .Dixon (2020). Genetically-programmed, mesenchymal stromal cell-laden & mechanically strong 3D bioprinted scaffolds for bone repair. Journal of Controlled Release. 325. 335-346.
• Jalal, Aveen R. And Dixon, James E. (2020). Efficient Delivery of Transducing Polymer Nanoparticles for Gene-mediated Induction of Osteogenesis for Bone Regeneration. Frontiers in Bioengineering and Biotechnology. 8. 849.
• Eltaher, Hoda M.; Abukunna, Fatima E.; Ruiz-Cantu, Laura; Stone, Zack; Yang, Jing; Dixon, James E. (2020). Human-scale Tissues with Patterned Vascular Networks by Additive Manufacturing of Sacrificial Sugar-Protein Composites. Acta Biomaterialia. 113. 339-349.

Ingrid Dreveny

• Oliva, M.L.V., Dreveny I., Emsley J. (2020). ‘Exosites expedite blood coagulation’ J Biol Chem., 295(45), 15208-15209. DOI: 10.1074/jbc.H120.016301
• Kaira, B.G., Slater, A., mccrae, K.R., Dreveny, I., Ummay, S.,Mutch, N.J., Searle, M., Emsley, J. (2020). ‘Factor XII and kininogen asymmetric assembly with gc1qr/C1QBP/P32 is governed by allostery’ Blood, 136(14), 1685-1697. DOI: 10.1182/blood.2020004818
• Gunnell E.A., Al-Noori A., Muhsen U., Davies C.C., Dowden J., Dreveny I. (2020). ‘Structural and biochemical evaluation of bisubstrate inhibitors of protein arginine N-methyltransferases PRMT1 and CARM1 (PRMT4)’ Biochem. J., 477(4), 787-800. DOI: 10.1042/BCJ20190826

Lindy Durrant

• Brentville VA,  Metheringham RL, Daniels I,, Atabani S, Symonds P, Cook KW, Vankemmelbeke M , Choudhury R, Vaghela P, Gijon M, Meiners G, Krebber WJ, Melief CM,  Durrant LG.(2020). Targeting citrullinated vimentin and enolase with cytotoxic CD4 T cells relies upon MHC-II expression on tumors, reduces myeloid suppressor cells and directly kills tumor cells. J Immunother Cancer. Jun;8(1):e000560. DOI: 10.1136/jitc-2020-000560.
• Brentville VA, Vankemmelbeke M, Metheringham RL, Durrant LG (2020). Post-translational modifications such as citrullination are excellent targets for cancer therapy. Semin Immunol.  Jan 10:101393. DOI: 10.1016/j.smim.2020.101393.
• Tivadar ST, mcintosh RS, Chua JX, Moss R, Parsons T, Zaitoun AM, Madhusudan S, Durrant LG, Vankemmelbeke M (2020). Monoclonal Antibody Targeting Sialyl-di-Lewisa - Containing Internalizing and non-Internalizing Glycoproteins with Cancer Immunotherapy Development Potential. Mol Cancer Ther. Mol Cancer Ther.  Mar;19(3):790-801. Pii: molcanther.0221.2019. DOI: 10.1158/1535-7163.MCT-19-0221.
• Soliman C, Chua JX, Vankemmelbeke M, mcintosh RS, Guy AJ, Spendlove I, Durrant LG, Ramsland PA (2020). The terminal sialic acid of stage-specific embryonic antigen-4 has a crucial role in binding to a cancer-targeting antibody.J Biol Chem. Jan 24;295(4):1009-1020. DOI: 10.1074/jbc.RA119.011518
• Lande R, Palazzo R, Gestermann N, Jandus C, Falchi M, Spadaro F, Riccieri V, James EA, Butera A, Boirivant M, Feldmeyer L, Surbeck I, Di Lucca J, Stuber F, Spinelli FR, Botti E, Marinari B, Bianchi L, Pica R, Cerbelli B, Giannakakis K, Auteri SE, Daniels I, Durrant LG, Horstman S, Costanzo A, Romero P, Alessandri C, Conti F, Valesini G, Gilliet M, Chizzolini C, Frasca L (2020). Native/citrullinated LL37-specific T-cells help autoantibody production in Systemic Lupus Erythematosus. Sci Rep. Apr 3;10(1):5851. DOI: 10.1038/s41598-020-62480-3.
• Pearson JRD, Cuzzubbo S, mcarthur S, Durrant LG, Adhikaree J, Tinsley CJ, Pockley AG, mcardle SEB (2020). Immune Escape in Glioblastoma Multiforme and the Adaptation of Immunotherapies for Treatment. Front Immunol.  Oct 15;11:582106. DOI: 10.3389/fimmu.2020.582106. Ecollection 2020
• Houvast RD, Baart VM, Bhairosingh SS, Cordfunke RA, Chua JX, Vankemmelbeke M, Parsons T, Kuppen PJK, Durrant LG, Vahrmeijer AL, Sier CFM (2020). Glycan-Based Near-infrared Fluorescent (NIRF) Imaging of Gastrointestinal Tumors: a Preclinical Proof-of-Concept In Vivo Study. Mol Imaging Biol.  Dec;22(6):1511-1522. DOI: 10.1007/s11307-020-01522-8.
• Vankemmelbeke M, mcintosh RS, Chua JX, Kirk T, Daniels I, Patsalidou M, Moss R, Parsons T, Scott D, Harris G, Ramage JM, Spendlove I, Durrant LG (2020). Engineering the Human Fc Region Enables Direct Cell Killing by Cancer Glycan-Targeting Antibodies without the Need for Immune Effector Cells or Complement. Cancer Res. 2020 Aug 15;80(16):3399-3412. DOI: 10.1158/0008-5472.CAN-19-3599.
• Soliman C, Guy AJ, Chua JX, Vankemmelbeke M, mcintosh RS, Eastwood S, Truong VK, Elbourne A, Spendlove I, Durrant LG, Ramsland PA (2020). Molecular and structural basis for Lewis glycan recognition by a cancer-targeting antibody. Biochem J.  Sep 18;477(17):3219-3235. DOI: 10.1042/BCJ20200454.PMID: 32789497

Isioma Egbuniwe

• Boonsri B, et al., (2020). 'Effect of Combining EGFR Tyrosine Kinase Inhibitors and Cytotoxic Agents on Cholangiocarcinoma Cells', Cancer Res Treat., Oct 7. DOI: 10.4143/crt.2020.585

Ian Ellis

• Rakha EA, Miligy IM, Quinn CM, Provenzano E, Shaaban AM, Marchiò C, Toss MS, Gallagy G, Murray C, Walshe J, Katayama A, Eldib K, Badr N, Tanchel B, Millican-Slater R, Purdie C, Purnell D, Pinder SE, Ellis IO, Lee AHS.Retrospective observational study of HER2 immunohistochemistry in borderline breast cancer patients undergoing neoadjuvant therapy, with an emphasis on Group 2 (HER2/CEP17 ratio ≥2.0, HER2 copy number <4.0 signals/cell) cases. Br J Cancer. 2021 Mar 24. DOI: 10.1038/s41416-021-01351-8. Online ahead of print.
• Syed BM, Green AR, Rakha EA, Morgan DAL, Ellis IO, Cheung KL. Age-Related Biology of Early-Stage Operable Breast Cancer and Its Impact on Clinical Outcome. Cancers (Basel). 2021 Mar 19;13(6):1417.
• Hickey TE, Selth LA, Chia KM, Laven-Law G, Milioli HH, Roden D, Jindal S, Hui M, Finlay-Schultz J, Ebrahimie E, Birrell SN, Stelloo S, Iggo R, Alexandrou S, Caldon CE, Abdel-Fatah TM, Ellis IO, Zwart W, Palmieri C, Sartorius CA, Swarbrick A, Lim E, Carroll JS, Tilley WD. The androgen receptor is a tumor suppressor in estrogen receptor-positive breast cancer. Nat Med. 2021 Feb;27(2):310-320.
• Parks RM, Albanghali MA, Syed BM, Green AR, Ellis IO, Cheung KL. Patterns of biomarker expression in patients treated with primary endocrine therapy - a unique insight using core needle biopsy tissue microarray. Breast Cancer Res Treat. 2021 Feb;185(3):647-655.
• Rakha EA, Quinn CM, Foschini MP, Muñoz Martin M, Dabbs DJ, Lakhani S, Varga Z, Pinder SE, Schmitt FC, Reis-Filho JS, Fox SB, Ellis IO, Tan PH, Mihai R. Metaplastic carcinomas of the breast without evidence of epithelial differentiation: a diagnostic approach for management. Histopathology. 2021 Apr;78(5):759-771.
• Duffy SW, Vulkan D, Cuckle H, Parmar D, Sheikh S, Smith RA, Evans A, Blyuss O, Johns L, Ellis IO, Myles J, Sasieni PD, Moss SM. Effect of mammographic screening from age 40 years on breast cancer mortality (UK Age trial): final results of a randomised, controlled trial. Lancet Oncol. 2020 Sep;21(9):1165-1172.
• Kurozumi S, Alsaleem M, Monteiro CJ, Bhardwaj K, Joosten SEP, Fujii T, Shirabe K, Green AR, Ellis IO, Rakha EA, Mongan NP, Heery DM, Zwart W, Oesterreich S, Johnston SJ. Targetable ERBB2 mutation status is an independent marker of adverse prognosis in estrogen receptor positive, ERBB2 non-amplified primary lobular breast carcinoma: a retrospective in silico analysis of public datasets. Breast Cancer Res. 2020 Aug 11;22(1):85. 
• Parks RM, Albanghali M, Syed BM, Green AR, Ellis IO, Cheung KL. Biology of Oestrogen-Receptor Positive Primary Breast Cancer in Older Women with Utilisation of Core Needle Biopsy Samples and Correlation with Clinical Outcome. Cancers (Basel). 2020 Jul 27;12(8):2067.
• Lee AHS, Hodi Z, Soomro I, Sovani V, Abbas A, Rakha E, Ellis IO. Histological clues to the diagnosis of metastasis to the breast from extramammary malignancies. Histopathology. 2020 Aug;77(2):303-313.
• Abdel-Fatah TMA, Ball GR, Thangavelu PU, Reid LE, mccart Reed AE, Saunus JM, Duijf PHG, Simpson PT, Lakhani SR, Pongor L, Gyorffy B, Moseley PM, Green AR, Pockley AG, Caldas C, Ellis IO, Chan SYT. Association of Sperm-Associated Antigen 5 and Treatment Response in Patients With Estrogen Receptor-Positive Breast Cancer. JAMA Netw Open. 2020 Jul 1;3(7):e209486.
• Alfarsi LH, El Ansari R, Masisi BK, Parks R, Mohammed OJ, Ellis IO, Rakha EA, Green AR. Integrated Analysis of Key Differentially Expressed Genes Identifies DBN1 as a Predictive Marker of Response to Endocrine Therapy in Luminal Breast Cancer. Cancers (Basel). 2020 Jun 12;12(6):1549.
• Joseph C, Alsaleem M, Orah N, Narasimha PL, Miligy IM, Kurozumi S, Ellis IO, Mongan NP, Green AR, Rakha EA. Elevated MMP9 expression in breast cancer is a predictor of shorter patient survival. Breast Cancer Res Treat. 2020 Jul;182(2):267-282. DOI: 10.1007/s10549-020-05670-x. Epub 2020 May 22.PMID: 32445177
• Alfarsi LH, El Ansari R, Masisi BK, Parks R, Mohammed OJ, Ellis IO, Rakha EA, Green AR. Integrated Analysis of Key Differentially Expressed Genes Identifies DBN1 as a Predictive Marker of Response to Endocrine Therapy in Luminal Breast Cancer. Cancers (Basel). 2020 Jun 12;12(6):1549. DOI: 10.3390/cancers12061549.PMID: 32545448
• Joseph C, Alsaleem M, Orah N, Narasimha PL, Miligy IM, Kurozumi S, Ellis IO, Mongan NP, Green AR, Rakha EA. Elevated MMP9 expression in breast cancer is a predictor of shorter patient survival. Breast Cancer Res Treat. 2020 Jul;182(2):267-282. DOI: 10.1007/s10549-020-05670-x. Epub 2020 May 22.PMID: 32445177
• Lee AHS, Hodi Z, Soomro I, Sovani V, Abbas A, Rakha E, Ellis IO. Histological clues to the diagnosis of metastasis to the breast from extramammary malignancies. Revised version. Histopathology. 2020 May 12. DOI: 10.1111/his.14141. Online ahead of print.PMID: 32396659
• Pareja F, Toss MS, Geyer FC, da Silva EM, Vahdatinia M, Sebastiao APM, Selenica P, Szatrowski A, Edelweiss M, Wen HY, Mihai R, Varga Z, Foschini MP, Rubin BP, Ellis IO, Chandarlapaty S, Jungbluth AA, Brogi E, Weigelt B, Reis-Filho JS, Rakha EA. Immunohistochemical assessment of HRAS Q61R mutations in breast adenomyoepitheliomas. Histopathology. 2020 May;76(6):865-874. DOI: 10.1111/his.14057.PMID: 31887226
• Saidy B, Rakha EA, Green AR, Ellis IO, Martin SG, Storr SJ. Retrospective assessment of cyclin-dependent kinase 5 mrna and protein expression and its association with patient survival in breast cancer. J Cell Mol Med. 2020 Apr 30. DOI: 10.1111/jcmm.15268. Online ahead of print.PMID: 32352232 Free article.
• El Ansari R, Alfarsi L, Craze ML, Masisi BK, Ellis IO, Rakha EA, Green AR. The solute carrier SLC7A8 is a marker of favourable prognosis in ER-positive low proliferative invasive breast cancer. Breast Cancer Res Treat. 2020 May;181(1):1-12. DOI: 10.1007/s10549-020-05586-6. Epub 2020 Mar 21.PMID: 32200487 Free PMC article.
• Johnston SJ, Syed BM, Parks RM, Monteiro CJ, Caruso JA, Green AR, Ellis IO, Hunt KK, Karakas C, Keyomarsi K, Cheung KL. Cytoplasmic Cyclin E Is an Independent Marker of Aggressive Tumor Biology and Breast Cancer-Specific Mortality in Women over 70 Years of Age. Cancers (Basel). 2020 Mar 18;12(3):712. DOI: 10.3390/cancers12030712.PMID: 32197318 Free PMC article.
• Hoon Tan P, Ellis I, Allison K, Brogi E, Fox SB, Lakhani S, Lazar AJ, Morris EA, Sahin A, Salgado R, Sapino A, Sasano H, Schnitt S, Sotiriou C, van Diest P, White VA, Lokuhetty D, Cree IA; WHO Classification of Tumours Editorial Board. The 2019 WHO classification of tumours of the breast. Histopathology. 2020 Feb 13. DOI: 10.1111/his.14091. Online ahead of print.PMID: 32056259
• Alfarsi LH, El-Ansari R, Craze ML, Masisi BK, Mohammed OJ, Ellis IO, Rakha EA, Green AR. Co-Expression Effect of SLC7A5/SLC3A2 to Predict Response to Endocrine Therapy in Oestrogen-Receptor-Positive Breast Cancer. Int J Mol Sci. 2020 Feb 19;21(4). Pii: E1407. DOI: 10.3390/ijms21041407.
• Ogden A, Bhattarai S, Sahoo B, Mongan NP, Alsaleem M, Green AR, Aleskandarany M, Ellis IO, Pattni S, Li XB, Moreno CS, Krishnamurti U, Janssen EA, Jonsdottir K, Rakha E, Rida P, Aneja R. Combined HER3-EGFR score in triple-negative breast cancer provides prognostic and predictive significance superior to individual biomarkers. Sci Rep. 2020 Feb 20;10(1):3009. DOI: 10.1038/s41598-020-59514-1.

Libby Ellis

• Shariff-Marco S, Ellis L, Yang J, Koo J, John EM, Keegan THM, Cheng I, Monroe KR, Vigen C, Kwan ML, Lu Y, Bernstein L, Wu AH, Gomez SL, Kurian AW. (2020). 'Hospital Characteristics and Breast Cancer Survival in the California Breast Cancer Survivorship Consortium', JCO Oncol Pract. ,16, e517-e528. DOI: 10.1200/OP.20.00064
• Oh DL, Santiago-Rodríguez EJ, Canchola AJ, Ellis L, Tao L, Gomez SL. (2020) 'Changes in Colorectal Cancer 5-Year Survival Disparities in California, 1997-2014'. Cancer Epidemiol Biomarkers Prev., 29, 1154-1161. DOI: 10.1158/1055-9965.EPI-19-1544
• Linnenbringer E, Geronimus AT, Davis KL, Bound J, Ellis L, Gomez SL (2020). 'Associations between breast cancer subtype and neighborhood socioeconomic and racial composition among Black and White women', Breast Cancer Res Treat, 180, 437-447. DOI: 10.1007/s10549-020-05545-1
• Fowler H, Belot A, Ellis L, Maringe C, Luque-Fernandez MA, Njagi EN, Navani N, Sarfati D, Rachet B. (2020).  'Comorbidity prevalence among cancer patients: a population-based cohort study of four cancers', BMC Cancer, 20, 2. DOI: 10.1186/s12885-019-6472-9

Jonas Emsley

• Hyo Jung Kim, Yaoxian Xu, Anastasis Petri, Karen Vanhoorelbeke, James T.B. Crawley & Jonas Emsley, 2021, Crystal structure of ADAMTS13 CUB domains and their role in global latency. Science Advances, 16 Apr 2021:7 (16), eabg4403, DOI: 10.1126/sciadv.abg4403
• Nicholas A. Arce, Wenpeng Cao, Alexander Brown, Emily R. Legan, Moriah S. Wilson, Pete Lollar, Michael C. Berndt, Jonas Emsley, X. Frank Zhang, and Renhao Li. 202. Activation of von Willebrand factor via mechanical unfolding of its discontinuous autoinhibitory module. Nature communications, 2021, 12, 2360
• Emma-Ruoqi Xu, Jonas Emsley 2021. Factor VIII/VWF complex caught on camera. Blood. 2021, 137(21):2865-2866. DOI: 10.1182/blood.2021010716.
• López-Gálvez R, de la Morena-Barrio ME, Miñano A, Pathak M, Marcos C, Emsley J, Caballero T, López-Trascasa M, Vicente V, Corral J, López-Lera A. 2021. Thrombin in the Activation of the Fluid Contact Phase in Patients with Hereditary Angioedema Carrying the F12 P.Thr309Lys Variant.. Clinical reviews in allergy & immunology, 2021, 60(3):357-368. DOI: 10.1007/s12016-021-08840-x.
• Slater A, Di Y, Clark JC, Jooss NJ, Martin EM, Alenazy FO, Thomas MR, Ariëns RA, Herr AB, Poulter NS, Emsley J, Watson SP. 2021. Structural characterisation of a novel GPVI nanobody-complex reveals a biologically active domain-swapped GPVI dimer.. Blood. 2021;137(24):3443-3453. DOI: 10.1182/blood.2020009440.
• Nizamudeen ZA, Xu ER, Karthik V, Halawa M, Arkill KP, Jackson AM, Bates DO, Emsley J. 2021. Structural assessment of SARS-cov2 accessory protein ORF7a predicts LFA-1 and Mac-1 binding potential.. Bioscience reports. 41(1):BSR20203837
• Jonas Emsley, Micha\l B. Ponczek, Aleksandr Shamanaev, Alec laplace, S. Kent Dickeson, Priyanka Srivastava, Mao-fu Sun, Andras Gruber, Christian Kastrup, Jonas Emsley, and David Gailani 2020. The evolution of factor XI and the kallikrein-kinin system. Blood Advances. (2020) 4 (24): 6135–6147. doi.org/10.1182/bloodadvances.2020002456
• Shamanaev A, Emsley J, Gailani D.  2020. Proteolytic activity of contact factor zymogens. J Thromb Haemost. 2021 Feb;19(2):330-341.
• Grossman S, Soukarieh F, Richardson W, Liu R, Mashabi A, Emsley J, Williams P, Cámara M, Stocks MJ. 2020. Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator pqsr. European Journal of Medicinal Chemistry. 208:112778
• Maria Luiza Vilela Oliva, Ingrid Dreveny, and Jonas Emsley 2020. Exosites expedite blood coagulation. Journal of Biological Chemistry, 295(45), p.15208–15209.
• Orvillo F, de la Morena-Barrio ME, Marcos-Bravo C, López-Trascasa M, Vicente V, Emsley J, Caballero T, Corral J, López-Lera A.2020. The FXII c.-4T>C Polymorphism as a Disease Modifier in Patients With Hereditary Angioedema Due to the FXII p.Thr328Lys Variant. Frontiers in Genetics. 11:1033.
• Ribeiro JFR, Cianni L, Li C, Warwick TG, de Vita D, Rosini F, Dos Reis Rocho F, Martins FCP, Kenny PW, Lameira J, Leitão A, Emsley J, Montanari CA 2020. Crystal structure of Leishmania mexicana cysteine protease B in complex with a highly potent azadipeptide nitrile inhibitor. Bioorganic & Medicinal Chemistry. 28(22):115743
• López-Gálvez R, de la Morena-Barrio ME, López-Lera A, Pathak M, Miñano A, Serrano M, Borgel D, Roldán V, Vicente V, Emsley J, Corral J. 2020. Factor XII in PMM2-CDG patients: role of N-glycosylation in the secretion and function of the first element of the contact pathway.. Orphanet J Rare Dis;15(1):280.
• Bubacarr G Kaira, Alexandre Slater, Keith R mccrae, Ingrid Dreveny, Um-May Sumya, Nicola J Mutch, Mark Searle, and Jonas Emsley 2020. Factor XII and kininogen asymmetric assembly with gc1qr/C1QBP/P32 is governed by allostery. Blood. 136(14):1685-1697
• Soukarieh F, Liu R, Romero M, Roberston SN, Richardson W, Lucanto S, Oton EV, Qudus NR, Mashabi A, Grossman S, Ali S, Sou T, Kukavica-Ibrulj I, Levesque RC, Bergström CAS, Halliday N, Mistry SN, Emsley J, Heeb S, Williams P, Cámara M, Stocks MJ.  2020. Hit Identification of New Potent pqsr Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa.. Frontiers in chemistry. 8:204
• Jonas Emsley 2020. Plasma kallikrein's low gear. Blood. 135 (8): 518–519.

Mattea Finelli

• Castroflorio E, den Hoed J, Svistunova D, Finelli MJ, Cebrian-Serrano A, Corrochano S, Bassett AR, Davies B, Oliver PL. (2021). 'The Ncoa7 locus regulates V-atpase formation and function, neurodevelopment and behaviour. Cell Mol Life Sci. 2021 Apr;78(7):3503-3524. DOI: 10.1007/s00018-020-03721-6.
• Feneberg E, Charles PD, Finelli MJ, Scott C, Kessler BM, Fischer R, Ansorge O, Gray E, Talbot K, Turner MR. (2020). 'Detection and quantification of novel C-terminal TDP-43 fragments in ALS-TDP.' Brain Pathol. 10:e12923. DOI: 10.1111/bpa.12923.
• Finelli MJ. (2020). 'Redox Post-translational Modifications of Protein Thiols in Brain Aging and Neurodegenerative Conditions-Focus on S-Nitrosation.' Front Aging Neurosci. 12:254. DOI: 10.3389/fnagi.2020.00254.
• Feneberg E, Gordon D, Thompson AG, Finelli MJ, Dafinca R, Candalija A, Charles PD, Mäger I, Wood MJ, Fischer R, Kessler BM, Gray E, Turner MR, Talbot K. (2020). 'An ALS-linked mutation in TDP-43 disrupts normal protein interactions in the motor neuron response to oxidative stress.' Neurobiol Dis. 144:105050. DOI: 10.1016/j.nbd.2020.105050.
• Williamson MG, Finelli MJ, Sleigh JN, Reddington A, Gordon D, Talbot K, Davies KE, Oliver PL. (2020). 'Neuronal over-expression of Oxr1 is protective against ALS-associated mutant TDP-43 mislocalisation in motor neurons and neuromuscular defects in vivo.' Hum Mol Genet. 28(21):3584-3599. DOI: 10.1093/hmg/ddz190.

Hester Franks

• Stoddart LA, Kindon ND, Otun O, Harwood CR, Patera F, Veprintsev DB, Woolard J, Briddon SJ, Franks HA, Hill SJ, Kellam B (2020) 'Ligand-directed covalent labelling of a GPCR with a fluorescent tag in live cells' Commun Biol 3:722

Kevin Gaston

• Marcolino de Assis Jr M., Siddiqui Y.H., van den Bosch M., Poole A.W., Jayaraman P.S., and Gaston K. (2020) Blood platelets stimulate cancer extravasation through tgfb-mediated down-regulation of PRH/HHEX. Oncogenesis, 9:10.
• Kitchen P, Lee KY, Clark D, Lau N, Lertsuwan J, Sawasdichai A, Satayavivad J, Oltean S, Afford S, Gaston K, Jayaraman P.S. (2020) A runaway PRH/HHEX-Notch3 positive feedback loop drives cholangiocarcinoma and determines response to CDK4/6 inhibition. Cancer Research, 80:757-770.

Pavel Gershkovich

• Feng W, Qin C, Chu Y, Berton M, Bong Lee J, Zgair A, Bettonte S, Stocks MJ, Constantinescu CS, Barrett DA, Fischer PM, Gershkovich P.  (2021) "Natural sesame oil is Superior to pre-digested lipid formulations and purified triglycerides in Promoting the intestinal lymphatic transport and systemic bioavailability of Cannabidiol". Eur J Pharm Biopharm. 2021 Mar 4:S0939-6411(21)00057-6.
• Shao H, Foley DW, Huang S, Abbas AY, Lam F, Gershkovich P, Bradshaw TD, Pepper C, Fischer PM, Wang S. (2021). "Structure-based design of highly selective 2,4,5-trisubstituted pyrimidine CDK9 inhibitors as anti-cancer agents". Eur J Med Chem. 2021 Mar 15;214:113244.
• Al-Beltagi S, Preda CA, Goulding LV, James J, Pu J, Skinner P, Jiang Z, Wang BL, Yang J, Banyard AC, Mellits KH, Gershkovich P, Hayes CJ, Nguyen-Van-Tam J, Brown IH, Liu J, Chang KC. (2021).  "Thapsigargin Is a Broad-Spectrum Inhibitor of Major Human Respiratory Viruses: Coronavirus, Respiratory Syncytial Virus and Influenza A Virus". Viruses. 2021 Feb 3;13(2):234.
• Ali J, Bong Lee J, Gittings S, Iachelini A, Bennett J, Cram A, Garnett M, Roberts CJ, Gershkovich P. (2021) Development and optimisation of simulated salivary Fluid for biorelevant oral cavity dissolution. Eur J Pharm Biopharm. 2021 Mar;160:125-133.
• Zgair A, Dawood Y, Ibrahem SM, Lee JB, Feng W, Fischer PM, Gershkovich P. (2021) "Strawberry Decreases Intraluminal and Intestinal Wall Hydrolysis of Testosterone Undecanoate." Molecules. 2021 Jan 5;26(1):233.
• Qin C, Chu Y, Feng W, Fromont C, He S, Ali J, Lee JB, Zgair A, Berton M, Bettonte S, Liu R, Yang L, Monmaturapoj T, Medrano-Padial C, Ugalde AAR, Vetrugno D, Ee SY, Sheriston C, Wu Y, Stocks MJ, Fischer PM, Gershkovich P. (2020) "Targeted delivery of lopinavir to HIV reservoirs in the mesenteric lymphatic System by lipophilic ester prodrug approach". J Control Release. 2021 Jan 10;329:1077-1089.
• Franco V, Gershkovich P, Perucca E, Bialer M. (2020). "The Interplay Between Liver First-Pass Effect and Lymphatic Absorption of Cannabidiol and Its Implications For Cannabidiol Oral Formulations." Clin Pharmacokinet. 2020 Dec;59(12):1493-1500.
• Qin C, Feng W, Chu Y, Lee JB, Berton M, Bettonte S, Teo YY, Stocks MJ, Fischer PM, Gershkovich P. (2020) "Development and validation of a cost-effective and Sensitive bioanalytical HPLC-UV method for determination of lopinavir in rat and Human plasma." Biomed Chromatogr. 2020 Nov;34(11):e4934 
• Monteiro PF, Gulfam M, Monteiro CJ, Travanut A, Abelha TF, Pearce AK, Jerôme C, Grabowska AM, Clarke PA, Collins HM, Heery DM, Gershkovich P, Alexander C. (2020) "Synthesis of micellar-like terpolymer nanoparticles with reductively-cleavable Cross-links and evaluation of efficacy in 2D and 3D models of triple negative Breast cancer." J Control Release. 2020 Jul 10;323:549-564.
• Bouzinab K, Summers HS, Stevens MFG, Moody CJ, Thomas NR, Gershkovich P, Weston N, Ashford MB, Bradshaw TD, Turyanska L. "Delivery of Temozolomide and N3-Propargyl Analog to Brain Tumors Using an Apoferritin Nanocage." (2020) ACS Appl Mater Interfaces. 2020 Mar 18;12(11):12609-12617.
• Ali J, Chiang M, Lee JB, Voronin GO, Bennett J, Cram A, Kagan L, Garnett MC, Roberts CJ, Gershkovich P. (2020) "Is rat a good model for assessment of particulate-Based taste-masked formulations?" Eur J Pharm Biopharm. 2020 Jan;146:1-9.

Anna Grabowska

• Nasir A, Cardall A, Othman RT, Nicolaou N, Lourdusamy A, Linke F, Onion D, Ryzhova M, Cameron H, Valente C, Korshunov A, Pfister SM, Grabowska AM, Kerr ID and Coyle B (2021) ABCB1 inhibition provides a novel therapeutic target to block TWIST1 induced migration in medulloblastoma Neuro-Oncology Advances  (In Press)
• Linke F, Aldighieri M, Lourdusamy A, Grabowska AM, Stolnik S,  Kerr ID, Merry CLR, Coyle B (2020) 3D hydrogels reveal Medulloblastoma subgroup differences and identify extracellular matrix subtypes that predict patient outcome. J. Path (In Press)
• Pearce AK, Anane-Adjei AB, Cavanagh RJ, Monteiro PF, Bennett TM, Taresco V, Clarke PA, Ritchie AA, Alexander MR, Grabowska AM, Alexander C (2020) Effects of Polymer 3D Architecture, Size and Chemistry on Biological Transport and Drug Delivery In Vitro and in Orthotopic Triple Negative Breast Cancer Models. Advanced Healthcare Materials  9(22): p. 2000892.
• Taresco V, Abelha TF, Cavanagh RJ, Vasey CE, Anane-Adjei AB, Pearce AK, Monteiro PF, Spriggs KA, Clarke P, Ritchie A, Martin S, Rahman R, Grabowska AM, Ashford MB and Alexander C (2021) Functionalised block co-polymer pro-drug nanoparticles with anti-cancer efficacy in 3D spheroids and in an orthotopic triple negative breast cancer model. Advanced Therapeutics 4(1):2000103
• Boonsri B, Yacqub-Usman K, Thintharua P, Myint KZ, Sae-Lao T, Collier P, Suriyonplengsaeng C, Larbcharoensub N, Balasubramanian B, Venkatraman S, Egbuniwe IU, Gomez D, Mukherjee A Kumkate S, Janvilisri T, Zaitoun AM, Kuakpaetoon T, Tohtong R, Grabowska AM, Bates DO, Wongprasert K (2020) Effect of Combining EGFR Tyrosine Kinase Inhibitors and Cytotoxic Agents on Cholangiocarcinoma Cells. Cancer Research and Treatment (In Press)
• Ritchie AA, Clarke PA, Dixon J, Grabowska AM (2020) The Jacket with Pulling Power - a novel approach to early stage evaluation of magnetic nanoparticles. Animal Technology & Welfare. 19(2):166
• Ashworth JC, Morgan RL, Lis-Slimak K, Jones S, Spence K, Slater CE,Thompson JL, Grabowska AM, Clarke RB, Farnie G, Merry CLR (2020) A user-defined peptide gel for controlled 3D culture models of cancer and disease jove 166: e61710
• Pal A, Ashworth JC, Collier P, Probert C, Jones S, Pernaut-Leza E, Meakin M, Ritchie AA, Onion D, Clarke PA, Allegrucci C, Grabowska AM (2020) A 3D heterotypic breast cancer model demonstrates a role for mesenchymal stem cells in driving a proliferative and invasive phenotype. Cancers 12(8): 2290
• Travanut A, Monteiro PF, Oelmann S, Howdle SM, Grabowska AM, Clarke PA, Ritchie AA, Meier MAR and Alexander  C  (2020) Synthesis of Passerini-3CR polymers and assembly into cytocompatible polymersomes. Macromolecular Rapid Communications: p2000321
• Fromont C, Atzori  A, Kaur  D, Hashmi L, Greco G, Cabanillas A, Nguyen HV, Jones DH, Garzón M, Varela A, Stevenson B, Iacobini G, Lenoir M, Rajesh S, Box C, Kumar J, Grant P, Novitskaia V, Morgan J, Sorrell F, Redondo F, Kramer A, Harris C., Leighton B, Vickers S, Cheetham S, Kenyon C, Grabowska AM, Overduin M, Berditchevski F, Weston C, Knapp S, Fischer P, Butterworth S (2020) Discovery of highly selective inhibitors of calmodulin-dependent kinases that restore insulin sensitivity in the diet-induced obese in vivo mouse model. J. Med. Chem. 63(3):6784
• Monteiro PF, Gulfam M, Monteiro CJ, Travanut A, Abelha TF, Pearce AK, Jerôme C, Grabowska AM, Clarke PA, Collins HM, Heery DM, Gershkovich P, Alexander C (2020) Synthesis of micellar-like terpolymer nanoparticles with reductively-cleavable cross-links and evaluation of efficacy in 2D and 3D models of triple negative breast cancer. J. Cont. Rel. 323:549

Andrew Green

• Sneha S, Baker SC, Green A, Storr S, Aiyappa R, Martin S, Pors K. (2021) Intratumoural Cytochrome P450 Expression in Breast Cancer: Impact on Standard of Care Treatment and New Efforts to Develop Tumour-Selective Therapies. Biomedicines. Mar 12;9(3):290. DOI: 10.3390/biomedicines9030290.

Ruth Griffin

• Karyal, C., Hughes, J., Kelly, M. L., Luckett, C. J., Kaye, P. V.., Cockayne, A., Minton, N. P., Griffin, R. (2021). "Colonisation Factor CD0873, an Attractive Oral Vaccine Candidate against Clostridioides difficile", Microorganisms., 9(2):306. DOI: 10.3390/microorganisms9020306.

Ian Hall

• Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis. Allen RJ, Guillen-Guio B, Oldham JM, Ma SF, Dressen A, Paynton ML, Kraven LM, Obeidat M, Li X, Ng M, Braybrooke R, Molina-Molina M, Hobbs BD, Putman RK, Sakornsakolpat P, Booth HL, Fahy WA, Hart SP, Hill MR, Hirani N, Hubbard RB, mcanulty RJ, Millar AB, Navaratnam V, Oballa E, Parfrey H, Saini G, Whyte MKB, Zhang Y, Kaminski N, Adegunsoye A, Strek ME, Neighbors M, Sheng XR, Gudmundsson G, Gudnason V, Hatabu H, Lederer DJ, Manichaikul A, Newell JD Jr, O'Connor GT, Ortega VE, Xu H, Fingerlin TE, Bossé Y, Hao K, Joubert P, Nickle DC, Sin DD, Timens W, Furniss D, Morris AP, Zondervan KT, Hall IP, Sayers I, Tobin MD, Maher TM, Cho MH, Hunninghake GM, Schwartz DA, Yaspan BL, Molyneaux PL, Flores C, Noth I, Jenkins RG, Wain LV. Am J Respir Crit Care Med. 2020 Mar 1;201(5):564-574. DOI: 10.1164/rccm.201905-1017OC.
• FLT1: a potential therapeutic target in sepsis-associated ARDS? Hall IP. Lancet Respir Med. 2020 Mar;8(3):219-220. DOI: 10.1016/S2213-2600(19)30404-7.
• Proinflammatory Effects in Ex Vivo Human Lung Tissue of Respirable Smoke Extracts from Indoor Cooking in Nepal. Kc B, Mahapatra PS, Thakker D, Henry AP, Billington CK, Sayers I, Puppala SP, Hall IP. Ann Am Thorac Soc. 2020 Jun;17(6):688-698. DOI: 10.1513/annalsats.201911-827OC.
• Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium. Portelli MA, Dijk FN, Ketelaar ME, Shrine N, Hankinson J, Bhaker S, Grotenboer NS, Obeidat M, Henry AP, Billington CK, Shaw D, Johnson SR, Pogson ZE, Fogarty A, mckeever TM, Nickle DC, Bossé Y, van den Berge M, Faiz A, Brouwer S, Vonk JM, de Vos P, Brandsma CA, Vermeulen CJ, Singapuri A, Heaney LG, Mansur AH, Chaudhuri R, Thomson NC, Holloway JW, Lockett GA, Howarth PH, Niven R, Simpson A, Blakey JD, Tobin MD, Postma DS, Hall IP, Wain LV, Nawijn MC, Brightling CE, Koppelman GH, Sayers I. JCI Insight. 2020 Apr 23;5(8):e132446. DOI: 10.1172/jci.insight.132446.
• Phenotypic and functional translation of IL33 genetics in asthma. Ketelaar ME, Portelli MA, Dijk FN, Shrine N, Faiz A, Vermeulen CJ, Xu CJ, Hankinson J, Bhaker S, Henry AP, Billington CK, Shaw DE, Johnson SR, Benest AV, Pang V, Bates DO, Pogson ZEK, Fogarty A, mckeever TM, Singapuri A, Heaney LG, Mansur AH, Chaudhuri R, Thomson NC, Holloway JW, Lockett GA, Howarth PH, Niven R, Simpson A, Tobin MD, Hall IP, Wain LV, Blakey JD, Brightling CE, Obeidat M, Sin DD, Nickle DC, Bossé Y, Vonk JM, van den Berge M, Koppelman GH, Sayers I, Nawijn MC. J Allergy Clin Immunol. 2021 Jan;147(1):144-157. DOI: 10.1016/j.jaci.2020.04.051.
• Chronic obstructive pulmonary disease and related phenotypes: polygenic risk scores in population-based and case-control cohorts. Moll M, Sakornsakolpat P, Shrine N, Hobbs BD, demeo DL, John C, Guyatt AL, mcgeachie MJ, Gharib SA, Obeidat M, Lahousse L, Wijnant SRA, Brusselle G, Meyers DA, Bleecker ER, Li X, Tal-Singer R, Manichaikul A, Rich SS, Won S, Kim WJ, Do AR, Washko GR, Barr RG, Psaty BM, Bartz TM, Hansel NN, Barnes K, Hokanson JE, Crapo JD, Lynch D, Bakke P, Gulsvik A, Hall IP, Wain L; International COPD Genetics Consortium; spirometa Consortium, Weiss ST, Silverman EK, Dudbridge F, Tobin MD, Cho MH. Lancet Respir Med. 2020 Jul;8(7):696-708. DOI: 10.1016/S2213-2600(20)30101-6.
• Assessing the impact of posture on diaphragm morphology and function using an open upright MRI system-A pilot study. Safavi S, Arthofer C, Cooper A, Harkin JW, Prayle AP, Sovani MP, Bolton CE, Gowland PA, Hall IP. Eur J Radiol. 2020 Sep;130:109196. DOI: 10.1016/j.ejrad.2020.109196.
• Variants associated with HHIP expression have sex-differential effects on lung function. Fawcett KA, Obeidat M, Melbourne C, Shrine N, Guyatt AL, John C, Luan J, Richmond A, Moksnes MR, Granell R, Weiss S, Imboden M, May-Wilson S, Hysi P, Boutin TS, Portas L, Flexeder C, Harris SE, Wang CA, Lyytikäinen LP, Palviainen T, Foong RE, Keidel D, Minelli C, Langenberg C, Bossé Y, Van den Berge M, Sin DD, Hao K, Campbell A, Porteous D, Padmanabhan S, Smith BH, Evans DM, Ring S, Langhammer A, Hveem K, Willer C, Ewert R, Stubbe B, Pirastu N, Klaric L, Joshi PK, Patasova K, Massimo M, Polasek O, Starr JM, Karrasch S, Strauch K, Meitinger T, Rudan I, Rantanen T, Pietiläinen K, Kähönen M, Raitakari OT, Hall GL, Sly PD, Pennell CE, Kaprio J, Lehtimäki T, Vitart V, Deary IJ, Jarvis D, Wilson JF, Spector T, Probst-Hensch N, Wareham NJ, Völzke H, Henderson J, Strachan DP, Brumpton BM, Hayward C, Hall IP, Tobin MD, Wain LV. Wellcome Open Res. 2020 Jun 1;5:111. DOI: 10.12688/wellcomeopenres.15846.1. Ecollection 2020.
• Reduced inflammatory responses to SARS-cov-2 infection in children presenting to hospital with COVID-19 in China. Qian G, Zhang Y, Xu Y, Hu W, Hall IP, Yue J, Lu H, Ruan L, Ye M, Mei J. Eclinicalmedicine. 2021 Apr 15:100831. DOI: 10.1016/j.eclinm.2021.100831.

Nick Hannan

• RIMLAND, C. A., TILSON, S. G., MORELL, C. M., TOMAZ, R. A., LU, W. Y., ADAMS, S. E., GEORGAKOPOULOS, N., OTAIZO-CARRASQUERO, F., MYERS, T. G., FERDINAND, J. R., GIESECK, R. L., 3RD, SAMPAZIOTIS, F., TYSOE, O. C., ROSS, A., KRAICZY, J. M., WESLEY, B., MURARO, D., ZILBAUER, M., ONISCU, G. C., HANNAN, N. R. F., FORBES, S. J., SAEB-PARSY, K., WYNN, T. A. & VALLIER, L. 2021. Regional Differences in Human Biliary Tissues and Corresponding In Vitro-Derived Organoids. Hepatology, 73, 247-267.

Kim Hardie

• Barzan, G., A. Sacco, A., Mandrile, L., Giovannozzi, A.M., Brown, J., Portesi, C., Alexander, M.,  Williams, P., Hardie, K.R., and Rossi, A.M. (2020) New frontiers against multi-drug resistance: A Raman-based approach for rapid detection of bacterial susceptibility and biocide-induced antibiotic cross-tolerance. Sensors and Actuators B: Chemical. 309 https://doi.org/10.1016/j.snb.2020.127774
• Jordana-Lluch, E., Garcia, V., Kingdon, A., Singh, N., Alexander, C., Williams, P., and Hardie, K.R. (2020).  Development of a polymicrobial model to examine interactions between commensals and pathogens on skin. Frontiers in Microbiology 11:291. DOI: 10.3389/fmicb.2020.00291.
• Zhang, J., Brown, J., Scurr, D., Bullen, A., mclellan-Gibson, K., Williams, P.,  Alexander, M.R., Hardie, K.R., Gilmore, I.S., and P. D. Rakowska, P.D. (2020) Cryo-orbisims for 3D molecular imaging of a bacterial biofilm in its native state. Analytical Chemistry 92.13 9008-9015 https://doi.org/10.1021/acs.analchem.0c01125. 
• Hardie, K.R. (2020) Antimicrobial resistance: the good, the bad and the ugly. Invited Review Emerging Topics in Life Sciences. ETLS20190194. DOI: https://doi.org/10.1042/ETLS20190194
• Lary, D., Calvert, A., Nerlich, B., Segal, J., Vaughan, N., Randle, J.  And Hardie, K.R. (2020). Improving children’s and their visitors’ hand hygiene compliance. Journal of Infection Prevention 20.2, 60-67 DOI: https://doi.org/10.1177%2F1757177419892065.

John Heap

• Taylor, G. M. And Heap, J. T. (2020) ‘Design and Implementation of Multi-protein Expression Constructs and Combinatorial Libraries using Start-Stop Assembly’, Meth. Mol. Biol., 2205, pp. 219–237.

Stephan Heeb

• Huertas-Rosales, O., Romero, M., Chan, K. G., Hong, K. W., Cámara, M., Heeb, S., Barrientos-Moreno, L., Molina-Henares, M. A., Travieso, M. L., Ramos-González, M. I., Espinosa-Urgel, M. (2021). 'Genome-wide analysis of targets for post-transcriptional regulation by Rsm proteins in Pseudomonas putida', Front. Mol. Biosci., 8, 624061, DOI: 10.3389/fmolb.2021.624061.

Mohammad Ilyas

• Nestarenkaite A, Fadhil W, Rasmusson A, Susanti S, Hadjimichael E, Laurinaviciene A, Ilyas M, Laurinavicius A. (2020).  ‘Immuno-interface score to predict outcome in colorectal cancer independent of microsatellite instability status’. Cancers, 12, 2902. Https://doi.org/10.3390/cancers12102902

Andrew Jackson

• Nizamudeen Z, Xu E, Karthik V, Halawa M, Arkill K, Jackson AM, Bates D, Emsley J. 2021 Structural assessment of SARS-cov2 accessory protein ORF7a predicts LFA-1 and Mac-1 binding potential. Biosci. Rep. DOI: 10.1042/BSR20203837

Victoria James

• GOMZIKOVA, M, JAMES, V and RIZVANOV, A, 2021. Mitochondria donation: current understanding and mitochondria transplantation strategies Frontiers in Cell and Developmental Biology. 9,
• OGURCOV, S, SHULMAN, L, GARANINA, E, BAICHURINA, I, KUZNETCOV, M, MASGUTOVA, G, KOSTENNIKOV, A, RIZVANOV, A, JAMES, V and MUKHAMEDSHINA, Y, 2021. Blood serum cytokine levels in patients with subacute spinal cord injury: a pilot study to search for biomarkers of injury severity and level Brain Science. 11(3),
• CHULPANOVA DS, GILAZIEVA ZE, KLETUKHINA SK, AIMALETDINOV AM, GARANINA EE, JAMES V and RIZVANOV AA, 2021. Cytochalasin B-Induced Membrane Vesicles from Human Mesenchymal Stem Cells Overexpressing IL2 Are Able to Stimulate CD8+ T-Killers to Kill Human Triple Negative Breast Cancer Cells Biology. 10(2), 141
• CHULPANOVA DS, SOLOVYEVA VV, JAMES V, ARKHIPOVA SS, GOMZIKOVA MO, GARANINA EE, AKHMETZYANOVA ER, TAZETDINOVA LG, KHAIBOULLINA SF and RIZVANOV AA, 2020. Human Mesenchymal Stem Cells Overexpressing Interleukin 2 Can Suppress Proliferation of Neuroblastoma Cells in Co-Culture and Activate Mononuclear Cells In Vitro. Bioengineering (Basel, Switzerland). 7(2),

Sheela Jayaraman

• Kitchen P, Lee KY, Clark D, Lau N, Lertsuwan J, Sawasdichai A, Satayavivad J, Oltean S, Afford S, Gaston K, Jayaraman PS. ( 2020) ' A Runaway PRH/HHEX-Notch3-Positive Feedback Loop Drives Cholangiocarcinoma and Determines Response to CDK4/6 Inhibition'. Cancer Res. Feb 15;80(4):757-770.
• Marcolino E, Siddiqui YH, van den Bosch M, Poole AW, Jayaraman PS, Gaston K. (2020) 'Blood platelets stimulate cancer extravasation through tgfβ-mediated downregulation of PRH/HHEX.' Oncogenesis. Feb 4;9(2):10.

Simon Johnson

• Babaei-Jadidi R, Dongre A, Miller S, Castellanos Uribe M, Nateri AS, Bradding P, May ST, Clements D, Johnson SR. Mast cell tryptase release contributes to disease progression in lymphangioleiomyomatosis. American Journal of Respiratory and Critical Care Medicine. 2021 In press
• Chernbumroong S, Johnson JI, Gupta N, Miller S, mccormack FX, Garibaldi JM Johnson SR. Machine learning identifies sub-phenotypes predicting disease manifestations and outcomes in lymphangioleiomyomatosis. European Respiratory Journal. 2021 https://doi.org/10.1183/13993003.03036-2020
• Bottolo L, Miller S, Johnson SR. Sphingolipid, fatty acid and phospholipid metabolites are associated with disease severity and mtor inhibition in lymphangioleiomyomatosis. Thorax 2020 http://dx.doi.org/10.1136/thoraxjnl-2019-214241
• Taveira-dasilva A, Johnson SR, Johnson JI, Julien-Williams P, Stylianou, M, Moss J. Pregnancy in lymphangioleiomyomatosis: clinical and lung function outcomes in two national cohorts. Thorax 2020 Oct;75(10):904-907. DOI: 10.1136/thoraxjnl-2020-214987. Http://dx.doi.org/10.1136/thoraxjnl-2020-214987
• Ketelaar ME, Portelli MA, Nicole Dijk F, Shrine N, Faiz A, Vermeulen CJ, Xu C, Hankinson J, Bhaker DS, Henry AP, Billington CK, Shaw DE, Johnson SR, Benest AV, Pang V, Bates D, Pogson ZEK, Fogarty A, M. Mckeever T, Singapuri A, Heaney L, Mansur AH, Chaudhuri R, Thomson NC, Holloway JW,. Lockett GA, Howarth PH, Niven R, Simpson A, Tobin MD, Hall IP, Wain LV, Blakey JD, Brightling CE, Obeidat M, Sin DD, Nickle C, Bossé Y, Vonk JM, van den Berge M, Koppelman GH, Sayers I, Nawijn MC. Phenotypic and functional translation of IL33 genetics in asthma. Journal of Allergy and Clinical Immunology 2020 May 19:S0091-6749(20)30680-1. DOI: 10.1016/j.jaci.2020.04.051.
• Clements D, Miller S, Johnson SR. Pulmonary Lymphangioleiomyomatosis originates in the pleural mesothelial cell population. Medical Hypotheses. 2020 https://doi.org/10.1016/j.mehy.2020.109703
• Miller S, Stewart I, Clements D, Soomro I, Babaei-Jadidi R, Johnson SR. Evolution of lung pathology in LAM: associations with disease course and treatment response. Journal of Pathology: Clinical Research. July 2020; 6: 215–226 https://doi.org/10.1002/cjp2.162
• Portelli MA, Dijk NF, Shrine N, Hankinson J, Bhaker S, Ketelaar M, Grotenboer NE, Obeidat M, Henry AP, Billington CK, Shaw D, Johnson SR, Pogson ZEK, Fogarty A, mckeever TM, Nickle DC, Bossé Y, van den Berge M, Faiz A, Brouwer S, Vonk JM, de Vos P, Singapuri A, Heaney L, Mansur AH, Chaudhuri R, Thomson NC, Holloway JW, Lockett GA, Howarth PH, Niven R, Simpson A, Blakey JD, Tobin MD, Postma DS, Hall IP, Wain L, Nawijn MC, Brightling CE, Koppelman GH, Sayers I. Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and airway epithelium in asthma. JCI Insight 2020;5(8):e132446. Https://doi.org/10.1172/jci.insight.132446.
• Clements D, Babaei-Jadidi R, Johnson SR. (2021) Mechanisms of Lung Cyst Formation. In: Gupta N, Wikenheiser-Brokamp KA, mccormack FX. (eds) Diffuse Cystic Lung Diseases. Respiratory Medicine. Humana, Cham. Https://doi.org/10.1007/978-3-030-63365-3_2
• Marciniak SJ and Johnson SR Pneumothorax and the biology of Birt-Hogg-Dubé syndrome. Thorax. 2020. Http://dx.doi.org/10.1136/thoraxjnl-2020-214861

Barrie Kellam

• Soave, M., Kellam, B., Woolard, J., Briddon, S. J., Hill, S. J. (2020). Nanobit Complementation to Monitor Agonist-Induced Adenosine A1 Receptor Internalization. SLAS Disc., 25, 186-194.
• Gillis, A., Gondin, A. B., Kliewer, A., Sanchez, J., Lim, H. D., Alamein, C., Manandhar, P., Santiago, M., Fritzwanker, S., Schmidel, F., Katte, T. A., Reekie, T., Grimsey, N. L., Kassiou, M., Kellam, B., Krasel, C., Halls, M. L., Connor, M., Lane, J. R., Schulz, S., Christie, M. J., Canals, M. (2020). Low Intrinsic Efficacy for G Protein Activation Can Explain the Improved Side Effect Profiles of New Opioid Agonists. Sci. Signal., 13 (625), eaaz3140.
• Comeo, E., Kindon, N. D., Soave, M., Stoddart, L. A., Kilpatrick, L. E., Scammells, P. J., Hill, S. J., Kellam, B.  (2020). Subtype-Selective Fluorescent Ligands as Pharmacological Research Tools for the Human Adenosine A2A Receptor. J. Med. Chem., 63 (5), 2656-2672.
• Stephenson, Z. A., Harvey, R. F., Pryde, K. R., Mistry, S., Hardy, R. E., Serreli, R., Chung, I., Allen, T. E., Stoneley, M., macfarlane, M., Fischer, P. M., Hirst, J., Kellam, B., Willis, A. E. (2020). Identification of a Novel Toxicophore in Anti-Cancer Chemotherapeutics That Targets Mitochondrial Respiratory Complex I. Elife, 9, e55845.
• Baker, J. G., Fromont, C., Bruder, M., Thompson, K. S. J., Kellam, B., Hill, S. J., Gardiner, S. M., Fischer, P. M., (2020). Using Esterase Selectivity to Determine the in Vivo Duration of Systemic Availability and Abolish Systemic Side-Effects of Topical β-Blockers. ACS Pharmacol Transl Sci., 3(4), 737-748.
• Soave, M., Heukers, R., Kellam, B., Woolard, J., Smit, M. J., Briddon, S. J., Hill, S. J. (2020). Monitoring Allosteric Interactions with CXCR4 Using nanobit Conjugated Nanobodies. Cell Chem Biol., 27(10), 1250-1261.e5.
• Matos, T. K. B., Batista, P. H. J., Rocho, F. Dos R., Vita, D. De, Pearce, N., Kellam, B., Montanari, C. A., Leitão, A. (2020). Synthesis and Matched Molecular Pair Analysis of Covalent Reversible Inhibitors of the Cysteine Protease CPB. Bioorg. Med. Chem. Lett., 30 (18), 127439.
• Stoddart, L. A., Kindon, N. D., Otun, O., Harwood, C. R., Patera, F., Veprintsev, D. B., Woolard, J., Briddon, S. J., Franks, H. A., Hill, S. J., Kellam, B. (2020) Ligand-Directed Covalent Labelling of a GPCR with a Fluorescent Tag in Live Cells. Commun. Biology, 3 (1), 722.
• Damaskinaki, F.-N., Moran, L. A., Garcia, A., Kellam, B., Watson, S. P. (2021). Overcoming Challenges in Developing Small Molecule Inhibitors for GPVI and CLEC-2. Platelets, 1–9.
• Stoddart, L. A., Kilpatrick, L. E., Corriden, R., Kellam, B., Briddon, S. J., Hill, S. J. (2021). Efficient G Protein Coupling Is Not Required for Agonist‐mediated Internalization and Membrane Reorganization of the Adenosine A3 Receptor. Faseb J., 35 (4), e21211.
• Comeo, E., Trinh, P., Nguyen, A. T., Nowell, C. J., Kindon, N. D., Soave, M., Stoddart, L. A., White, J. M., Hill, S. J., Kellam, B., Halls, M. L., May, L. T., Scammells, P. J. (2021). Development and Application of Subtype-Selective Fluorescent Antagonists for the Study of the Human Adenosine A 1 Receptor in Living Cells. J. Med. Chem., in press.
• Goulding, J., Mistry, S.J., Soave, M., Woolard, J., Briddon, S.J., White, C.W., Kellam, B., Hill, S.J. (2021). Subtype selective fluorescent ligands based on ICI 118,551 to study the human β2-adrenoceptor in CRISPR/Cas9 genomeedited HEK293T cells at low expression levels. Pharmacy. Res. Perspect. In press

Laura Kilpatrick

• Kilpatrick L.E., Hill S.J. (2021). 'Transactivation of G protein-coupled receptors (gpcrs) and receptor tyrosine kinases (rtks): Recent insights using luminescence and fluorescence technologies', Curr Opin Endocr Metab Res., 16:102-112 DOI: 10.1016/j.coemr.2020.10.003.
• Stoddart L.A., Kilpatrick L.E., Corriden R., Kellam B., Briddon S.J., Hill S.J. (2021). 'Efficient G protein coupling is not required for agonist-mediated internalization and membrane reorganization of the adenosine A3 receptor,' FASEB J., 35 (4):e21211. DOI: 10.1096/fj.202001729RR.
• Peach C.J., Kilpatrick L.E., Woolard J., Hill S.J. (2021). 'Use of nanobit and nanobret to monitor fluorescent VEGF-A binding kinetics to VEGFR2/NRP1 heteromeric complexes in living cells.' Br J Pharmacol., epub DOI: 10.1111/bph.15426.
• Soave M, Stoddart LA, White CW, Kilpatrick LE, Goulding J, Briddon SJ, Hill SJ. (2021). 'Detection of genome-edited and endogenously expressed G protein-coupled receptors', FEBS J., epub DOI: 10.1111/febs.15729.
• White C.W., Kilpatrick L.E., Pfleger K.D.G., Hill S.J. (2020). 'A nanoluciferase biosensor to investigate endogenous chemokine secretion and receptor binding', iscience., 24 (1):102011. DOI: 10.1016/j.isci.2020.102011.
• Perpiñá-Viciano C., Işbilir A., Zarca A., Caspar B., Kilpatrick L.E., Hill S.J., Smit M.J., Lohse M.J., Hoffmann C. (2020). 'Kinetic Analysis of the Early Signaling Steps of the Human Chemokine Receptor CXCR4. Mol Pharmacol., 98(2):72-87. DOI: 10.1124/mol.119.118448
• Comeo E., Kindon N.D., Soave M., Stoddart L.A., Kilpatrick L.E., Scammells P.J., Hill S.J., Kellam B. (2020). 'Subtype-Selective Fluorescent Ligands as Pharmacological Research Tools for the Human Adenosine A2A Receptor', J Med Chem., 12;63(5):2656-2672. DOI: 10.1021/acs.jmedchem.9b01856.

Katalin Kovacs

• Dalwadi M.P., Orol Gomez, D., Walter, F., King J.R., Minton, N.P. Kovács, K, (2020). Using singular perturbation theory to determine kinetic parameters in a non-standard coupled enzyme assay, Journal of Mathematical Biology, 81: 649–690.

Charles Laughton

• Styliari, ID ; Taresco, V ; Theophilus, A ; Alexander, C ; Garnett, M ; Laughton, C (2020) 'Nanoformulation-by-design: an experimental and molecular dynamics study for polymer coated drug nanoparticles', Advances, 10, 19521-19533, DOI:10.1039/d0ra00408a
• De Albuquerque, S ; Cianni, L ; de Vita, D ; Duque, C ; Gomes, ASM ; Gomes, P; Laughton, C ; Leitao, A ; Montanari, CA ; Montanari, R ; Ribeiro, JFR; da Silva, JS ; Teixeira, C (2020) 'Molecular design aided by random forests and synthesis of potent trypanocidal agents as cruzain inhibitors for Chagas disease treatment', Chem. Biol. Drug. Des. 96, 948-960 DOI:10.1111/cbdd.13663

Arockia Lourdusamy

• Ahmad O, Chapman R, Storer L, Luo L, Resar L, Cohen K, Grundy RG, Lourdusamy A. (2021). Integrative molecular characterization of pediatric spinal ependymoma: The UK Children’s Cancer and Leukaemia Group study. Neuro-Oncology Advances. Https://doi.org/10.1093/noajnl/vdab043.
• Nasir A, Cardall A, Othman RT, Nicolaou N, Lourdusamy A, Linke F, David O, Marina R, Hanna C, Cara V, Andrey K, Stefan PM, Anna GM Ian KD, Coyle, B. (in press). ABCB1 inhibition provides a novel therapeutic target to block TWIST1 induced migration in medulloblastoma. Neuro-Oncology Advances.
• Meurs J, David S, Lourdusamy A, Storer L, Grundy R, Alexander M, Rahman R, Kim, D. (in press). Sequential 3D orbisims and LESA-MS/MS-based metabolomics for prediction of brain tumour relapse from sample-limited primary tissue archives. Analytical Chemistry
• Linke F, Aldighieri M, Lourdusamy A, Grabowska AM, Stolnik S, Kerr ID, Merry CLR, Coyle B. (2020). 3D hydrogels reveal medulloblastoma subgroup differences and identify extracellular matrix subtypes that predict patient outcome. J Pathol. Nov 18. DOI: 10.1002/path.5591.
• Vadakekolathu J, Lai C, Reeder S, Church SE, Hood T, Lourdusamy A, Rettig MP, Aldoss I, Advani AS, Godwin J, Wieduwilt MJ, Arellano M, Muth J, Yau TO, Ravandi F, Sweet K, Altmann H, Foulds GA, Stölzel F, Middeke JM, Ciciarello M, Curti A, Valk PJM, Löwenberg B, Gojo I, Bornhäuser M, dipersio JF, Davidson-Moncada JK, Rutella S. (2020). TP53 abnormalities correlate with immune infiltration and associate with response to flotetuzumab immunotherapy in AML. Blood Adv. Oct 27;4(20):5011-5024.
• Chédeville AL, Lourdusamy A, Monteiro AR, Hill R, Madureira PA. (2020). Investigating Glioblastoma Response to Hypoxia. Biomedicines 8 (9), 310
• Smith S, Rowlinson J, Estevez-Cebrero M, Onion D, Ritchie A, Clarke P, Wood, K, Diksin M, Lourdusamy A, Grundy R, Rahman R. (2020). Metabolism based isolation of invasive glioblastoma cells with specific gene signatures and tumorigenic potential. Neuro-Oncology Advances. 10.1093/noajnl/vdaa087.
• Canales Coutiño B, Cornhill ZE, Couto A, Mack NA, Rusu AD, Nagarajan U, Fan YN, Hadjicharalambous MR, Castellanos Uribe M, Burrows A, Lourdusamy A, Rahman R, May ST, Georgiou M. (2020). A Genetic Analysis of Tumor Progression in Drosophila Identifies the Cohesin Complex as a Suppressor of Individual and Collective Cell Invasion. Iscience. 26;23(6):101237.
• Rhein C, Mühle C, Lenz B, Richter-Schmidinger T, Kogias G, Boix F, Lourdusamy A, Dörfler A, Peters O, Ramirez A, Jessen F, Maier W, Hüll M, Frölich L, Teipel S, Wiltfang J, Kornhuber J, Müller CP. (2020). Association of a CAMK2A genetic variant with logical memory performance and hippocampal volume in the elderly. Brain Res Bull. 161:13-20.

Srinivasan Madhusudan

• ALI, R., ALBLIHY, A., MILIGY, I. M., ALABDULLAH, M. L., ALSALEEM, M., TOSS, M. S., ALGETHAMI, M., ABDEL-FATAH, T., MOSELEY, P., CHAN, S., MONGAN, N. P., NARAYAN, S., RAKHA, E. A. & MADHUSUDAN, S. (2021). Molecular disruption of DNA polymerase beta for platinum sensitisation and synthetic lethality in epithelial ovarian cancers. Oncogene, 40, 2496-2508.
• ALBLIHY, A., ALABDULLAH, M. L., ALI, R., ALGETHAMI, M., TOSS, M. S., MONGAN, N. P., RAKHA, E. A. & MADHUSUDAN, S. (2021). Clinicopathological and Functional Evaluation Reveal NBS1 as a Predictor of Platinum Resistance in Epithelial Ovarian Cancers. Biomedicines, 9.
• LU, X., REDON, C. E., TANG, W., PARVATHANENI, S., BOKHARI, B., DEBNATH, S., LI, X. L., MUYS, B. R., SONG, Y., PONGOR, L. S., SHEIKH, O., GREEN, A. R., MADHUSUDAN, S., LAL, A., AMBS, S., KHAN, J., ALADJEM, M. I. & SHARMA, S. (2021). Genome-Wide Analysis Unveils DNA Helicase RECQ1 as a Regulator of Estrogen Response Pathway in Breast Cancer Cells. Mol Cell Biol, 41.
• ALI, R., ALBLIHY, A., TOSS, M. S., ALGETHAMI, M., AL SUNNI, R., GREEN, A. R., RAKHA, E. A. & MADHUSUDAN, S. (2020b). XRCC1 deficient triple negative breast cancers are sensitive to ATR, ATM and Wee1 inhibitor either alone or in combination with olaparib. Ther Adv Med Oncol, 12, 1758835920974201.
• SAVVA, C., SADIQ, M., SHEIKH, O., KARIM, S., TRIVEDI, S., GREEN, A. R., RAKHA, E. A., MADHUSUDAN, S. & ARORA, A. (2021). Werner Syndrome Protein Expression in Breast Cancer. Clin Breast Cancer, 21, 57-73 e7.
• TIVADAR, S. T., MCINTOSH, R. S., CHUA, J. X., MOSS, R., PARSONS, T., ZAITOUN, A. M., MADHUSUDAN, S., DURRANT, L. G. & VANKEMMELBEKE, M. (2020). Monoclonal Antibody Targeting Sialyl-di-Lewis(a)-Containing Internalizing and Noninternalizing Glycoproteins with Cancer Immunotherapy Development Potential. Mol Cancer Ther, 19, 790-801.
• ALI, R., ALABDULLAH, M., ALBLIHY, A., MILIGY, I., MESQUITA, K. A., CHAN, S. Y., MOSELEY, P., RAKHA, E. A. & MADHUSUDAN, S. (2020a). PARP1 blockade is synthetically lethal in XRCC1 deficient sporadic epithelial ovarian cancers. Cancer Lett, 469, 124-133.

Stewart Martin

• Abdullah, N.A., Inman, M., Moody, C.J., Storr, S.J., and Martin, S.G. (2021) 'Cytotoxic and radiosensitising effects of a novel thioredoxin reductase inhibitor in breast cancer', Investigational New Drugs – in press
• Sneha, S., Baker, S.C., Green, A., Storr, S., Aiyappa, R., Martin, S., and Pors, K. (2021) 'Intratumoural Cytochrome P450 Expression in Breast Cancer: Impact on Standard of Care Treatment and New Efforts to Develop Tumour-Selective Therapies' Biomedicines 9(3), 290
• Taresco, V., Abelha, T.F., Cavanagh, R.J., Vasey, C.E., Anane‐Adjei, A.B., Pearce, A.K.,  Monteiro, P.F., Spriggs, K.A., Clarke, P., Ritchie, A., Martin, S., Rahman, R., Grabowska, A.M., Ashford, M.B., and Alexander, C. (2021) ‘Functionalized block co-polymer pro-drug nanoparticles with anti-cancer efficacy in 3D spheroids and in an orthotopic triple negative breast cancer model’, Advanced Therapeutics 4(1), 200010388
• Martin, S.G., Zhang, S., Yang, S., Saidy, B., Deen, S., and Storr, S.J., (2020) 'Dopamine and camp-regulated phosphoprotein 32kda (DARPP-32), protein phosphatase-1 and cyclin-dependent kinase 5 expression in ovarian cancer', J Cell Mol Med. 24 (16), 9165-9175
• Yao, A., Storr, S.J., Al-hadyan, K., Rahman, R., Smith, S., Grundy, R., Paine, S., and  Martin, S.G. (2020) ‘Thioredoxin system protein expression is associated with poor clinical outcome in adult and paediatric gliomas and medulloblastomas’, Molecular Neurobiology, 57(7), 2889-2901
• Saidy, B., Rakha, E.A., Green, A.R., Ellis, I.O., Martin, S.G., and Storr, S.J. (2020) 'Retrospective assessment of cyclin-dependent kinase 5 mrna and protein expression and its association with patient survival in breast cancer', J Cell Mol Med. Jun;24(11):6263-6271.
• Jeggo, P.A., Martin, S.G., Williams, K.J., and Prise, K.M. (2020) ‘Advances in Radiation Biology–Highlights from the 16th ICRR special feature: introductory editorial’, The British Journal of Radiology 93 (1115), 20209006

Alvaro Mata

• Wu, Y., Fortunato, G.M., Okesola, B.O., Pellerej di Brocchetta, F.L., Suntornnond, R., Connelly, J., De Mria, C., Rodriguez-Cabello, J.C., Vozzi, G., Wang, W., Mata, A. (2021). ‘An interfacial self-assembling bioink for the manufacturing of capillary-like structures with tuneable and anisotropic permeability’, Biofabrication, 10.1088/1758-5090/abe4c3.
• Primo, G., Mata, A. (2021). ‘3D Patterning within hydrogels for the recreation of functional biological environments’, Advanced Functional Materials, 2009574, 10.1002/adfm.202009574.
• Sennett, M.L., Friedman, J.M., Ashley, B.S., Stoeckl, B.D., Patel, J.M., Alini, M., Cucchiarini, M., Eglin, D., Madry, H., Mata, A., Semino, C., Stoddart, M.J., Johnstone, B., Moutos, F.T., Estes, B.T., Guilak, F., Mauck, R.L., Dodge, G.R. (2021). ‘Long term outcomes of biomaterial-mediated repair of focal cartilage defects in a large animal model’, European Cells & Materials, 41, 40-51, 10.22203/ecm.v041a04.
• Barrett, D.W., Okesola, B.O., Costa, E., Thrasivoulou, C., Becker, D.L., Mata, A., Deprest, J.A., David, A.L., Chowdhury, T.T. (2020). ‘Potential sealing and repair of human FM defects after trauma with peptide amphiphiles and Cx43 antisense’, Prenatal Diagnosis, 41(1), 89-99, 10.1002/pd.5826.
• Hedegaard, C.L., Redondo-Gomez, C., Tan, B.Y., Ng. K.W., Loessner, D., Mata, A. (2020). ‘Peptide-protein co-assembling matrices as a biomimetic 3D model of ovarian cancer’, Science Advances, 6(40), 10.1126/sciadv.abb3298.
• Redondo-Gomez, C., Padilla-Lopategui, S., Azevedo, H.S., Mata, A. (2020). ‘Host-guest-mediated epitope presentation on self-assembled peptide hydrogel’, ACS Biomaterials Science & Engineering, 6(9), 4870-4880, 10.1021/acsbiomaterials.0c00549.
• Majkowska, A., Redondo-Gomez, C., Rice, A., Gonzalez, M., Inostroza-Brito, K.E., Collin, E., Rodriguez-Cabello, J.C., Del Rio Hernandez, A.E., Solito, E., Mata, A. (2020). ‘Interfacial self-assembly to spatially organise graphene oxide into hierarchical and bioactive structures’, Frontiers in Materials, 7(167), 10.3389/fmats.2020.00167.
• Hedegaard, C.L., Mata, A. (2020). ‘Integrating self-assembly and biofabrication for the development of structures with enhanced complexity and hierarchical control’, Biofabrication, 12(3), 10.1088/1758-5090/ab84cb.
• Derkus, B., Okesola, B.O., Barrett, D.W., D’Este, M., Chowdhury, T.T., Eglin, D., Mata, A (2020). ‘Multicomponent hydrogels for the formation of vascularized bone-like constructs in vitro’, Acta Biomaterialia 109, 82-94, 10.1016/j.actbio.2020.03.025.
• Wu, Y., Okesola, B.O., Xu, J., Korotkin, I., Berado, A., Corridori, I., Pellerej di Brocchetti, F.L., Kanczler, J., Feng, J., Li, W., Shi, Y., Nerukh, D., Farafonov, V., Wang, Y., Titirici, M.M., Karabasov, S., Oreffo, R.O.C., Rodriguez-Cabello, J.C., Vozzi, G., Azevedo, H.S., Pugno, N.M., Bailey, C.G., Wang, W., Mata, A. (2020). ‘Disordered protein-graphene oxide co-assembly and supramolecular biofabrication of functional fluidic devices’, Nature Communications 11 (1182), 10.1038/s41467-020-14716-z.
• Okesola, B.O., Shilei, N., Derkus, B., Galeano, C.C., Hasan, A., Wu, Y., Ramis, J., Buttery, L., Dawson, J., D’Este, M., Oreffo, R.O.C., Eglin, D., Sun, H., Mata, A. (2020). ,Growth factor-free multicomponent nanocomposite hydrogels that stimulate bone formation’, Advanced Functional Materials 30(14), 1906205, 10.1002/adfm.201906205.
• Okesola, B.O., Lau, H.K., Derkus, B., Boccorh, D.K., Wu, Y., Wark, A.W., Kiick, K.L., Mata, A. (2020). ‘Covalent co-assembly between resilin-like polypeptide and peptide amphiphile into hydrogels with controlled nanostruxture and improved mechanical properties’, Biomolecular Sciences, 3, 846-857, 10.1039/c9bm01796h.

Alan Mcintyre

• Wu, X., Niculite, C.M., Preda, M.B., Rossi, A., Tebaldi, T., Butoi, E., White, M.K., Tudoran, O.M., Petrusca, D.N., Jannasch, A.S. and Bone, W.P., Zong, X., Fang, F., Burlacu, A., Paulsen, M.T., Hancock, B.A., Sandusky, G.E., Mitra, S., Fishel, M.L., Buechlein, A., Ivan, C., Oikonomopoulos, C., Gorospe, M.,  Mosley, A., Radovich, M., Davé, U.P.,  Ragoussis,  J., Nephew, K.P.,  Mari,  B., Mcintyre, A., Konig, H., Ljungman, M., Cousminer, D.L., Macchi, P., Ivan, M., 2020. Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincnors. Nature communications, 11(1), pp.1-17.
• Tezcan, G., Garanina, E., Alsaadi, M., Gillazieva, Z.E., Martynova, E., Markelova, M.I., Arkhipova, S.S., Hamza, S., Mcintyre, A., Rizvanov, A.A. and Khaiboullina, S., 2020. Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer. Frontiers in immunology, 11, p.3734.

Cathy Merry

• Merry CLR. (2021) Exciting New Developments and Emerging Themes in Glycosaminoglycan Research. J Histochem Cytochem. 69(1):9-11
• Schneeberger PE, von Elsner L, Barker EL, Meinecke P, Marquardt I, Alawi M, Steindl K, Joset P, Rauch A, Zwijnenburg PJG, Weiss MM, Merry CLR, Kutsche K. (2020) Bi-allelic Pathogenic Variants in HS2ST1 Cause a Syndrome Characterized by Developmental Delay and Corpus Callosum, Skeletal, and Renal Abnormalities. Am J Hum Genet. 107(6):1044-1061.
• Ashworth JC, Morgan RL, Lis-Slimak K, Meade KA, Jones S, Spence K, Slater CE, Thompson JL, Grabowska AM, Clarke RB, Farnie G, Merry CLR. (2020) Preparation of a User-Defined Peptide Gel for Controlled 3D Culture Models of Cancer and Disease. J Vis Exp. (166)
• Ashworth JC, Thompson JL, James JR, Slater CE, Pijuan-Galitó S, Lis-Slimak K, Holley RJ, Meade KA, Thompson A, Arkill KP, Tassieri M, Wright AJ, Farnie G, Merry CLR. (2020) Peptide gels of fully-defined composition and mechanics for probing cell-cell and cell-matrix interactions in vitro. Matrix Biol. 85-86:15-33
• Linke F, Aldighieri M, Lourdusamy A, Grabowska AM, Stolnik S, Kerr ID, Merry CL, Coyle B. (2021) 3D hydrogels reveal medulloblastoma subgroup differences and identify extracellular matrix subtypes that predict patient outcome. J Pathol. 253(3):326-338

Nigel Minton

• Castro-Córdova, P., Mora-Uribe, P., Reyes-Ramírez, R., Cofré-Araneda, G., Orozco-Aguilar, J., Brito-Silva, C., Mendoza-León, M.J., Kuehne, S.A., Minton, N.P., Pizarro-Guajardo, M., Paredes-Sabja, D. (2021). ‘Entry of spores into intestinal epithelial cells contributes to recurrence of Clostridioides difficile infection’, Nat Commun.,12, 1140. DOI: 10.1038/s41467-021-21355-5.
• Mertaoja, A., Nowakowska, M.B., Mascher, G., Heljanko, V., Groothuis, D., Minton, N.P., Lindström, M. (2021), ‘CRISPR-Cas9-Based Toolkit for Clostridium botulinum Group II Spore and Sporulation Research’, Front Microbiol., 12, 617269. DOI: 10.3389/fmicb.2021.617269. 
• Bourgade, B., Minton, N.P., Islam, M.A. (2021). ‘Genetic and metabolic engineering challenges of C1-gas fermenting acetogenic chassis organisms’ FEMS Microbiol Rev., 45, fuab008. DOI: 10.1093/femsre/fuab008. 
• Mowday, A.M., Dubois, L.J., Kubiak, A.M., Chan-Hyams, J.V.E., Guise, C.P., Ashoorzadeh, A., Lambin, P., Ackerley, D.F., Smaill, J.B., Minton, N.P., Theys, J., Patterson, A.V. (2021). ‘Use of an optimised enzyme/prodrug combination for Clostridia directed enzyme prodrug therapy induces a significant growth delay in necrotic tumours’, Cancer Gene Ther.,  Feb 8. DOI: 10.1038/s41417-021-00296-7.
• Karyal, C., Hughes, J., Kelly, M.L., Luckett, J.C., Kaye, P.V., Cockayne, A., Minton, N.P., Griffin, R. (2021). ‘Colonisation Factor CD0873, an Attractive Oral Vaccine Candidate against Clostridioides difficile’, Microorganisms., 9, 306. DOI: 10.3390/microorganisms9020306. 
• Rumah, B.L., Stead, C.E., Claxton Stevens, B.H., Minton, N.P., Grosse-Honebrink, A., Zhang, Y. (2021) ‘Isolation and characterisation of Methylocystis spp. For poly-3-hydroxybutyrate production using waste methane feedstocks’, AMB Express., 11, 6. DOI: 10.1186/s13568-020-01159-4.
• Viacava, K., Meibom, K.L., Ortega, D., Dyer, S., Gelb, A., Falquet, L., Minton, N.P., Mestrot, A., Bernier-Latmani, R. (2020). ‘Variability in Arsenic Methylation Efficiency across Aerobic and Anaerobic Microorganisms’, Environ Sci Technol., 54, 14343-14351. DOI: 10.1021/acs.est.0c03908. Epub 2020 Oct 30.
• Jin, S., Bae, J., Song, Y., Pearcy, N., Shin, J., Kang, S., Minton, N.P., Soucaille, P., Cho, B.K. (2020). ‘Synthetic Biology on Acetogenic Bacteria for Highly Efficient Conversion of C1 Gases to Biochemicals’, Int J Mol Sci., 21, 7639. DOI: 10.3390/ijms21207639.
•  Bilverstone TW, Garland M, Cave RJ, Kelly ML, Tholen M, Bouley DM, Kaye P, Minton NP, Bogyo M, Kuehne SA, Melnyk RA. (2020), ‘The glucosyltransferase activity of C. Difficile Toxin B is required for disease pathogenesis’, plos Pathog., 16, e1008852. DOI: 10.1371/journal.ppat.1008852. 
• Dalwadi, M.P., Orol, D., Walter, F., Minton, N.P., King, J.R., Kovács, K. J. (2020), ‘Using singular perturbation theory to determine kinetic parameters in a non-standard coupled enzyme assay’, Math Biol., 81, 649-690. DOI: 10.1007/s00285-020-01524-8.
• Bommareddy, R.R., Wang, Y., Pearcy, N., Hayes, M., Lester, E., Minton, N.P., Conradie, A.V. (2020), ‘A Sustainable Chemicals Manufacturing Paradigm Using CO2 and Renewable H2’,  iscience, 26, 101218. DOI: 10.1016/j.isci.2020.101218.
• Kotte, A.K., Severn, O., Bean, Z., Schwarz, K., Minton, N.P., Winzer, K. (2020), ‘RRNPP-type quorum sensing affects solvent formation and sporulation in Clostridium acetobutylicum’, Microbiol (Reading), 166, 579-592. DOI: 10.1099/mic.0.000916.
• Seys, F.M., Rowe, P., Bolt, E.L., Humphreys, C.M., Minton, N.P. (2020) ‘A Gold Standard, CRISPR/Cas9-Based Complementation Strategy Reliant on 24 Nucleotide Bookmark Sequences’, Genes (Basel), 11, 458. DOI: 10.3390/genes11040458.
• Hanko, E.K.R., Paiva, A.C., Jonczyk, M., Abbott, M., Minton, N.P., Malys, N. (2020), ‘A genome-wide approach for identification and characterisation of metabolite-inducible systems’, Nat Commun., 11, 1213. DOI: 10.1038/s41467-020-14941-6.

Shailesh Mistry

• Soukarieh F., Liu R., Romero M., Robertson S.N., Richardson W., Lucanto S., Oton E.V., Qudus N.R., Mashabi A., Grossman S., Ali S., Sou T., Kukavica-Ibrulj I., Levesque R.C., Bergstöm C., Halliday N., Mistry S.N., Emsley J., Heeb S., Williams P., Camara M., Stocks M.J. (2020). 'Hit identification of new potent pqsr antagonists as inhibitors of quorum sensing in planktonic and biofilm grown Pseudomonas aeruginosa' Front. Chem., 8, 204, DOI: 10.3389/fchem.2020.00204.

Nigel Mongan

• ALBLIHY, A., et al. 2021. Clinicopathological and Functional Evaluation Reveal NBS1 as a Predictor of Platinum Resistance in Epithelial Ovarian Cancers. Biomedicines, 9.
• ALI, R., et al. 2021. Molecular disruption of DNA polymerase beta for platinum sensitisation and synthetic lethality in epithelial ovarian cancers. Oncogene.
• ALJOHANI, A. I., et al. 2020. The prognostic significance of wild-type isocitrate dehydrogenase 2 (IDH2) in breast cancer. Breast Cancer Res Treat, 179, 79-90.
• ALSAEED, S. A., et al. 2021. Prognostic significance of heat shock protein 90AA1 (HSP90alpha) in invasive breast cancer. J Clin Pathol.
• ALSALEEM, M. A., et al. 2020. A novel prognostic two-gene signature for triple negative breast cancer. Mod Pathol, 33, 2208-2220.
• DECIO, P., et al. 2021. Thiamethoxam exposure deregulates short ORF gene expression in the honey bee and compromises immune response to bacteria. Sci Rep, 11, 1489.
• GOMZIKOVA, M. O., et al. 2020. Immunosuppressive properties of cytochalasin B-induced membrane vesicles of mesenchymal stem cells: comparing with extracellular vesicles derived from mesenchymal stem cells. Sci Rep, 10, 10740.
• JOSEPH, C., et al. 2020. Elevated MMP9 expression in breast cancer is a predictor of shorter patient survival. Breast Cancer Res Treat, 182, 267-282.
• KARIRI, Y. A., et al. 2020. Prognostic significance of KN motif and ankyrin repeat domains 1 (KANK1) in invasive breast cancer. Breast Cancer Res Treat, 179, 349-357.
• KUROZUMI, S., et al. 2020. Targetable ERBB2 mutation status is an independent marker of adverse prognosis in estrogen receptor positive, ERBB2 non-amplified primary lobular breast carcinoma: a retrospective in silico analysis of public datasets. Breast Cancer Res, 22, 85.
• MCEWEN, G. K., et al. 2021. Retroviral integrations contribute to elevated host cancer rates during germline invasion. Nat Commun, 12, 1316.
• OGDEN, A., et al. 2020. Combined HER3-EGFR score in triple-negative breast cancer provides prognostic and predictive significance superior to individual biomarkers. Sci Rep, 10, 3009.
• ORFALI, N., et al. 2020a. All-trans retinoic acid (ATRA)-induced TFEB expression is required for myeloid differentiation in acute promyelocytic leukemia (APL). Eur J Haematol, 104, 236-250.
• ORFALI, N., et al. 2020b. Inhibition of UBE2L6 attenuates isgylation and impedes ATRA-induced differentiation of leukemic cells. Mol Oncol, 14, 1297-1309.
• RAKHA, E. A., et al. 2020. Visual histological assessment of morphological features reflects the underlying molecular profile in invasive breast cancer: a morphomolecular study. Histopathology, 77, 631-645.
• SHAFIEE, M. N., et al. 2020. Lipidomic Biomarkers in Polycystic Ovary Syndrome and Endometrial Cancer. Int J Mol Sci, 21.
• SIMPSON, S., et al. 2020. Molecular Characterisation of Canine Osteosarcoma in High Risk Breeds. Cancers (Basel), 12.

Abhik Mukherjee

• Boonsri, B., Yacqub-Usman, K., Thintharua, P., Myint KZ, S-L.T, Collier, P., Suriyonplengsaeng, C., Larbcharoensub, N., Balasubramanian, B., Venkatraman, S., Egbuniwe, I.U., Gomez, D., Mukherjee, A., Kumkate, S., Janvilisri, T., Zaitoun, A.M., Kuakpaetoon, T., Tohtong, R., Grabowska, A.M., Bates, D.O., Wongprasert, K. ‘Effect of Combining EGFR Tyrosine Kinase Inhibitors and Cytotoxic Agents on Cholangiocarcinoma Cells’, Cancer Res Treat. 2020 Oct 7. DOI: 10.4143/crt.2020.585. Online ahead of print.
• Heyman, T., Joseph, C., Craze, M., Green, A., Nolan, C., Oscar Rueda, O., Provenzano, E., Rakha, E., Ellis, I.O. and Mukherjee, A. ‘High tissue inhibitor of matrix-metalloproteinase 2 expression correlates with poor prognosis in breast cancer’, Abstracts . Virchows Arch 477, 1–390 (2020). Https://doi.org/10.1007/s00428-020-02938-x
• Richman,S.D., Williams, C.J., West, N.P., Seligmann, J., Shires, M., Dance, S., Pabial,P., Gasuad, K., Pham, L., Mangham, C., Mapstone, N., Bacon, C., Mukherjee, A., Ilyas, M., Coupland, S.,  Cross, S., Ridder, R., Shanmugam, K., Hudson, C., and Quirke, P., on behalf of the N6 Collaborators. ‘The N6 Consortium – The Northern Pathology Network’, Winter Meeting. Journal of Pathology Volume 250, Issue S1 Winter Meeting. Abstracts of the 212th Scientific Meeting of the Pathological Society of Great Britain & Ireland, 21–22 January 2020, London

Paloma Ordonez Moran

• Norkin M, Ordonez-Moran P & Huelsken J (2021). High-content targeted RNA-seq drug screening in organoids: TORNADO-seq application in colorectal cancer. Cell reports, in press.
• Dionellis, V. S., Norkin, M., Karamichali, A., Rossetti, G. G., Huelsken, J., Ordonez-Moran, P., & Halazonetis, T. D. (2021). Genomic Instability Profiles at the Single Cell Level in Mouse Colorectal Cancers of Defined Genotypes. Cancers, 13(6), 1267.
• Dafflon, C., Santamaría-Martínez, A., & Ordóñez-Morán, P. (2020). An Intrasplenic Injection Model for the Study of Cancer Stem Cell Seeding Capacity. Methods in molecular biology (Clifton, N.J.), 2171, 293–302.
• Dessen, P., Huelsken, J., & Ordóñez-Morán, P. (2020). Specific Gene Expression in Lgr5+ Stem Cells by Using Cre-Lox Recombination. Methods in molecular biology (Clifton, N.J.), 2171, 249–255.
• Hacker, D. L., & Ordóñez-Morán, P. (2020). Large-Scale Production of Recombinant Noggin and R-Spondin1 Proteins Required for the Maintenance of Stem Cells in Intestinal Organoid Cultures. Methods in molecular biology (Clifton, N.J.), 2171, 171–184.
• Norkin, M., Capdevila, C., Calderon, R. I., Su, T., Trifas, M., Ordóñez-Morán, P., & Yan, K. S. (2020). Single-Cell Studies of Intestinal Stem Cell Heterogeneity During Homeostasis and Regeneration. Methods in molecular biology (Clifton, N.J.), 2171, 155–167. Https://doi.org/10.1007/978-1-0716-0747-3_9

Poulam Patel

• O'Cathail M, Aznar-Garcia L, Sivanandan A, Diver C, Patel P, Tang PS, Christian J.( 2021).’ Use of Teleconsultations in a Regional Stereotactic Radiosurgery Service: Pilot Study.’ JMIR Form Res. Feb 5;5(2):e15598. DOI: 10.2196/15598.
• Elsheikh S, Kouzoukakis I, Fielden C, Li W, Lashin SE, Khair N, Raposo TP, Fadhil W, Rudland P, Aleskandarany M, Patel P, El-Tanani M, Ilyas M. (2020)’ Ran GTPase Is an independent prognostic marker in malignant melanoma which promotes tumour Cell migration and invasion’. J Clin Pathol. Jclinpath-2020-206871. DOI: 10.1136/jclinpath-2020-206871.
• Sun W, Xu Y, Yang J, Liao Z, Li T, Huang K, Patel P, Yan W, Chen Y. (2020).’The Prognostic significance of non-sentinel lymph node metastasis in cutaneous and Acral melanoma patients-A multicenter retrospective study’ . Cancer Commun (Lond). ;40(11):586-597. DOI: 10.1002/cac2.12101.
• He C , Ledezma UH , Gurnani P , Albelha T , Thurecht KJ , Correia R , Morgan SP , Patel P , Alexander C , Korposh S (2020). Surface polymer imprinted optical fibre Sensor for dose detection of dabrafenib. Analyst. 145(13):4504-4511. DOI: 10.1039/d0an00434k.
• Vasudev NS, Wilson M, Stewart GD, Adeyoju A, Cartledge J, Kimuli M, Datta S, Hanbury D, Hrouda D, Oades G, Patel P, Soomro N, Sullivan M, Webster J, Selby PJ, Banks RE. (2020).’ Challenges of early renal cancer detection: symptom patterns and Incidental diagnosis rate in a multicentre prospective UK cohort of patients Presenting with suspected renal cancer’. BMJ Open. May10(5):e035938. DOI: 10.1136/bmjopen-2019-035938
• Adhikaree J, Moreno-Vicente J, Kaur AP, Jackson AM, Patel PM. (2020).Resistance Mechanisms and Barriers to Successful Immunotherapy for Treating Glioblastoma. Cells. 9(2):263. DOI: 10.3390/cells9020263.
• Vasudev NS, Hutchinson M, Trainor S, Ferguson R, Bhattarai S, Adeyoju A, Cartledge J, Kimuli M, Datta S, Hanbury D, Hrouda D, Oades G, Patel P, Soomro N, Stewart GD, Sullivan M, Webster J, Messenger M, Selby PJ, Banks RE (2020). ‘UK Multicenter Prospective Evaluation of the Leibovich Score in Localized Renal Cell Carcinoma: Performance has Altered Over Time’. Urology. 136:162-168. DOI: 10.1016/j.urology.2019.09.044.

Sara Pijuan-Galito

• Yang, L., Pijuan-Galito, S., Rho, H. S., Vasilevich, A. S., Eren, A. D., Ge, L., Habibovic, P., Alexander, M. R., de Boer, J., Carlier, A., van Rijn, P., Zhou, Q. (2021) "High-Throughput Methods in the Discovery and Study of Biomaterials and Materiobiology". Chem. Rev. DOI: 10.1021/acs.chemrev.0c00752
• Nasir, A., Thorpe, J., Burroughs, L., Meurs, J., Pijuan-Galito, S., Irvine, D. J., Alexander, M. R., Denning, C.. (2021) "Discovery of a Novel Polymer for Xeno-Free, Long-Term Culture of Human Pluripotent Stem Cell Expansion". Adv. Healthc. Mater., 10, 6. DOI: 10.1002/adhm.202001448Reference
• Ashworth, J. C., Thompson, J. L., James, J. R., Slater, C. E., Pijuan-Galito, S., Lis-Slimak, K., Holley, R. J., Meade, K. A., Thompson, A., Arkill, K. P., Tassieri, M., Wright, A. J., Farnie, G., Merry, C. L. R. (2020) "Peptide gels of fully-defined composition and mechanics for probing cell-cell and cell-matrix interactions in vitro". Matrix Biol., 85-86, 15-33. DOI: 10.1016/j.matbio.2019.06.009

Ruman Rahman

• Woodward A, Pandele A, Abdelrazig S, Ortori CA, Khan I, Castellanos Uribe M, May S, Barrett DA, Grundy RG, Kim D-H, Rahman R (2021). ‘Integrated metabolomics and transcriptomics analysis using dual-extraction of metabolites and RNA from brain cancer cells’. In press; Metabolites.
• Meurs J, Scurr DJ, Storer L, Grundy RG, Alexander MR, Rahman R, Kim D-H (2021). ‘Surface mass spectrometry-based metabolomics of brain tumour relapse from sample-limited primary tissue archives’. In press; Analytical Chemistry.
• Robinson AJ, Jain A, Sherman HG, Hague RJM, Rahman R, Sanjuan-Alberte P, Rawson FJ (2021). ‘Towards hijacking bioelectricity in cancer to develop new bioelectronic medicine’. In press; Advanced Therapeutics.
• Vasey CE, Cavanagh RJ, Taresco V, Moloney C, Smith SJ, Rahman R, Alexander C (2021). ‘Polymer pro-drug nanoparticles for sustained release of cytotoxic drugs evaluated in patient-derived GBM cell lines and in situ gelling formulations’. Pharmaceutics 13, 208. * Contributed equally. DOI: 10.3390/pharmaceutics13020208
• Jain A, Trindale GF, Hicks JM, Potts JC, Rahman R, Hague RJM, Perez-Garcia L, Amabilino DB, Rawson F (2021). ‘Modulating the biological function of protein by tailoring the adsorption orientation on nanoparticles’. Journal of Colloid and Interface Science 587, 150-161.
• Mccrorie P, Mistry J, Taresco V, Lovato T, Fay M, Ritchie A, Clarke P, Smith SJ, Marlow M, Rahman R (2020). ‘Etoposide and olaparib polymer-coated nanoparticles within a bio-adhesive sprayable hydrogel for post-surgical localised delivery to brain tumours’. European Journal of Biopharmaceutics and Pharmaceutics 157, 108-120. * Contributed equally. Https://doi.org/10.1016/j.ejpb.2020.10.005
• Taresco V, Abelha T, Cavanagh R, Vasey CE, Pearce AK, Spriggs KA, Clarke P, Ritchie A, Martin S, Rahman R, Grabowska A, Ashford M, Alexander C (2020). ‘Functionalized block co-polymer pro-drug nanoparticles with anti-cancer efficacy in 3D spheroids and in an orthotopic triple negative breast cancer model’. Advanced Therapeutics 4, 2000103.
• Mccrorie P, Vasey C, Smith SJ, Marlow M, Alexander C, Rahman R (2020). ‘Biomedical engineering approaches to enhance nanotherapeutic delivery for malignant glioma’. Journal of Controlled Release 328, 917-931. Https://doi.org/10.1016/j.jconrel.2020.11.022
• Morris B, Curtin L, Hawkins-Daarud A, Hubbard ME, Rahman R, Smith SJ, Auer D, Tran NL, Hu LS, Swanson KR, Owen MR (2020). ‘Identifying the spatial and temporal dynamics of molecularly-distinct glioblastoma subpopulations’. Mathematical Biosciences and Engineering 17, 4905-4941.
• Smith SJ, Rowlinson J, Estevez-Cebrero M, Onion D, Ritchie A, Wood K, Diksin M, Lourdusamy A, Grundy RG, Rahman R (2020). ‘Metabolism based isolation of invasive glioblastoma cells with specific gene signatures and tumorigenic potential’. Neuro-Oncology Advances 2, 1-12. Https://doi-org.ezproxy.nottingham.ac.uk/10.1093/noajnl/vdaa087
• Coutino BC, Cornhill Z, Couto A, Mack NA, Rusu AD, Nagarajan U, Fan YN, Hadjicharalambous MR, Uribe MC, Burrows A, Lourdusamy A, Rahman R, May ST, Georgiou M (2020). ‘A genetic analysis of tumour progression in Drosophila identifies the cohesion complex as a suppressor of individual and collective cell invasion’. Iscience 23, 101237.
• Yao A, Storr SJ, Alhadyan K, Rahman R, Smith S, Grundy R, Paine S, Martin SG (2020). ‘Thioredoxin system protein is associated with poor clinical outcome in adult and paediatric gliomas and medulloblastomas’. Molecular Neurobiology 57, 2889-2901.
• Greco C, Taresco V, Pearce AK, Vasey CE, Smith S, Rahman R, Alexander C, Cavanagh RJ, Musumeci F, Schenone S (2020). ‘Development of pyrazolo[3,4-d]pyrimidine kinase inhibitors as potential clinical candidates for glioblastoma multiforme recurrences’. ACS Medicinal Chemistry Letters 11, 657-663.
• Vasilev A, Sofi R, Rahman R, Smith SJ, Teschemacher AG, Kasparov S (2020). ‘Using light for therapy of glioblastoma multiforme’. Brain Sciences 10, 75.

Emad Rakha

• Alblihy A, et al. (2021). Biomedicines 9(1).
• Alfarsi LH, et al. (2020a). BMC Cancer 20(1): 425.
• Alfarsi LH, et al. (2020b). Cancers (Basel) 12(6).
• Alfarsi LH, et al. (2020c). Int J Mol Sci 21(4).
• Ali R, et al. (2020a). Cancer Lett 469: 124-133.
• Ali R, et al. (2021). Oncogene 40(14): 2496-2508.
• Ali R, et al. (2020b). Ther Adv Med Oncol 12: 1758835920974201.
• Aljohani AI, et al. (2020a). Breast Cancer Res Treat 181(3): 541-551.
• Aljohani AI, et al. (2020b). Breast Cancer Res Treat 179(1): 79-90.
• Alsaeed SA, et al. (2021). J Clin Pathol. Epub ahead of print 2021/03/27.
• Alsaleem MA, et al. (2020). Mod Pathol 33(11): 2208-2220.
• Althobiti M, et al. (2020a). Histopathology 77(3): 437-448.
• Althobiti M, et al. (2020b). Breast Cancer Res Treat 182(3): 581-589.
• Ansari RE, et al. (2020). Br J Cancer 122(1): 94-101.
• Browning L, et al. (2020). J Clin Pathol. Epub ahead of print 2020/07/06.
• El Ansari R, et al. (2020). Breast Cancer Res Treat 181(1): 1-12.
• Elsharawy KA, et al. (2021a). Breast Cancer Res Treat 185(3): 615-627.
• Elsharawy KA, et al. (2021b). Histopathology. Epub ahead of print 2021/02/17.
• Elsharawy KA, et al. (2020a). Br J Cancer 123(10): 1543-1552.
• Elsharawy KA, et al. (2020b). Histopathology 76(5): 671-684.
• Gagliano T, et al. (2020). J Clin Invest 130(6): 3188-3204.
• Ibrahim A, et al. (2020). Breast 49: 267-273.
• Joseph C, et al. (2020a). Breast Cancer Res Treat 182(2): 267-282.
• Joseph C, et al. (2020b). Cancers (Basel) 13(1).
• Kader T, et al. (2020). NPJ Breast Cancer 6: 9.
• Kariri YA, et al. (2020a). Pathobiology 87(4): 218-231.
• Kariri YA, et al. (2021). Breast Cancer Res Treat 185(2): 293-305.
• Kariri YA, et al. (2020b). Breast Cancer Res Treat 179(2): 349-357.
• Katayama A, et al. (2021). Mod Pathol. Epub ahead of print 2021/02/03.
• Klimov S, et al. (2020). Front Oncol 10: 593211.
• Kurozumi S, et al. (2020a). Breast Cancer Res Treat 179(3): 557-564.
• Kurozumi S, et al. (2020b). Breast Cancer Res 22(1): 85.
• Lee AHS, et al. (2020). Histopathology 77(2): 303-313.
• Lizio MG, et al. (2021). Biomed Opt Express 12(2): 940-954.
• Masisi BK, et al. (2020). Histopathology 76(4): 498-508.
• Mihai R, et al. (2021). Histopathology 78(6): 871-881.
• Miligy IM, et al. (2020a). Br J Cancer 123(10): 1513-1520.
• Miligy IM, et al. (2020b). Br J Cancer 123(10): 1584.
• Miligy IM, et al. (2021). Br J Cancer 124(4): 856.
• Mittal K, et al. (2021). Cancer Metastasis Rev 40(1): 319-339.
• Mittal K, et al. (2020). Clin Cancer Res 26(12): 2898-2907.
• Morotti M, et al. (2021). Br J Cancer 124(2): 494-505.
• Ogden A, et al. (2020). Sci Rep 10(1): 3009.
• Pareja F, et al. (2020a). NPJ Breast Cancer 6: 20.
• Pareja F, et al. (2020b). Mod Pathol 33(6): 1056-1064.
• Pareja F, et al. (2020c). Histopathology 76(6): 865-874.
• Rakha E, et al. (2021a). Histopathology. Epub ahead of print 2021/04/09.
• Rakha EA, et al. (2020a). Histopathology 77(4): 631-645.
• Rakha EA, et al. (2021b). Br J Cancer. Epub ahead of print 2021/03/26.
• Rakha EA, et al. (2020b). Semin Cancer Biol. Epub ahead of print 2020/04/08.
• Rakha EA, et al. (2021c). Histopathology 78(5): 759-771.
• Rakha EA, et al. (2020c). J Clin Pathol. Epub ahead of print 2020/08/09.
• Saidy B, et al. (2020). J Cell Mol Med 24(11): 6263-6271.
• Sanz-Moreno A, et al. (2021). Breast Cancer Res 23(1): 42.
• Savva C, et al. (2021). Clin Breast Cancer 21(1): 57-73 e57.
• Siersbaek R, et al. (2020). Cancer Cell 38(3): 412-423 e419.
• Syed BM, et al. (2021). Cancers (Basel) 13(6).
• Toss M, et al. (2020a). J Clin Pathol 73(2): 76-82.
• Toss MS, et al. (2020b). Br J Cancer 122(10): 1496-1506.
• Toss MS, et al. (2020b). Br J Cancer 122(10): 1496-1506.
• Vangangelt KMH, et al. (2020a). Int J Cancer 146(8): 2296-2304.
• Vangangelt KMH, et al. (2020b). Breast Cancer Res Treat 179(1): 37-45.
• Williams B, et al. (2020). Histopathology 76

Judith Ramage

• Vankemmelbeke, M., mcintosh, R.S., Chua, J., Kirk, T., Daniels, I., Patsalidou, M., Moss, R., Parsons, T., Scott, D., Harris, G., Ramage, J.M., Spendlove, I., and Durrant, L.G. (2020) 'Engineering the human Fc-region enables direct cell killing by cancer glycan-targeting antibodies without the need for immune effector cells or complement', Cancer Res., 80, 3399-3412.

Frankie Rawson

• BENNETT, M. R., GURNANI, P., HILL, P. J., ALEXANDER, C. & RAWSON, F. J. 2020. Iron-Catalysed Radical Polymerisation by Living Bacteria. Angewandte Chemie International Edition, 59, 4750-4755.
• GIBNEY, S., HICKS, J. M., ROBINSON, A., JAIN, A., SANJUAN-ALBERTE, P. & RAWSON, F. J. 2021. Toward nanobioelectronic medicine: Unlocking new applications using nanotechnology. Wires Nanomed. Nanobiotech., n/a, e1693.
• HICKS, J., SILMAN, N., JACKSON, S., AYLOTT, J. & RAWSON, F. 2020. Mass transport of lipopolysaccharide induced H2O2 detected by an intracellular carbon nanoelectrode sensor. Bioelectrochemistry, 135, 107547.
• HICKS, J. M., YAO, Y.-C., BARBER, S., NEATE, N., WATTS, J., NOY, A. & RAWSON, F. 2021. Electric Field Induced Biomimetic Transmembrane Electron Transport using Carbon Nanotube Porins as Bipolar Electrodes.
• ROBINSON, A., JAIN, A., RAHMAN, R., ABAYZEED, S., HAGUE, R. & RAWSON, F. 2020. Impedimetric characterisation of bioelectronic nano-antennae. Chemrxiv, Preprint.
• ROBINSON, A. J., JAIN, A., SHERMAN, H. G., HAGUE, R. J. M., RAHMAN, R., SANJUAN-ALBERTE, P. & RAWSON, F. J. 2021. Toward Hijacking Bioelectricity in Cancer to Develop New Bioelectronic Medicine. Adv. Therap, n/a, 2000248.
• SANJUAN-ALBERTE, P., VAITHILINGAM, J., MOORE, J. C., WILDMAN, R. D., TUCK, C. J., ALEXANDER, M. R., HAGUE, R. J. & RAWSON, F. J. 2021. Development of Conductive Gelatine-Methacrylate Inks for Two-Photon Polymerisation. Polymers, 13, 1038.
• WOHLGEMUTH, F., GOMES, R. L., SINGLETON, I., RAWSON, F. J. & AVERY, S. V. 2020. Top-Down Characterization of an Antimicrobial Sanitizer, Leading From Quenchers of Efficacy to Mode of Action. Frontiers in microbiology, 11.

Timothy Ritzmann

• Ritzmann TA, Rogers HA, Paine SML, Storer LCD, Jacques TS, Chapman RJ, Ellison D, Donson AM, Foreman NK, Grundy RG (2020). 'A retrospective analysis of recurrent paediatric ependymoma reveals extremely poor survival and ineffectiveness of current treatments across central nervous system locations and molecular subgroups.' Pediatric Blood & Cancer, 67(9):e28426, 10.1002/pbc.28426.
• Andradas C, Byrne J, Kuchibhotla M, Ancliffe M, Jones AC, Carline B, Hii H, Truong A, Storer LCD, Ritzmann TA, Grundy RG, Gottardo NG, Endersby R. (2021) 'Assessment of Cannabidiol and Delta9-Tetrahydrocannabiol in Mouse Models of Medulloblastoma and Ependymoma.' Cancers, 13, 330, 10.3390/cancers13020330.
• Ritzmann T, Kilday JP, Grundy RG. (2021). 'Recurrent Paediatric Ependymoma: Destined to recur?'. Neuro-Oncology, noab066, https://doi.org/10.1093/neuonc/noab066.
• Williams G, mclean R, Liu JF, Ritzmann TA, Dandapani M, Sachdev P, Brougham M, Mitchell R, Conway NT, Law J, Cunnington A, Ogunnaike G, Brougham K, Bayman E, Walker DA. (2021) 'A multi-centre service evaluation of the impact of the COVID-19 pandemic on presentation of newly diagnosed cancers and type 1 diabetes in children in the UK.' medrxiv. DOI: 10.1101/2021.02.09.21251149.

Karen Robinson

• Robinson, K., and Lehours, P. (2020) 'Helicobacter, inflammation, immunology and vaccines', Helicobacter.  25 Suppl 1, e12737.
• Robinson, K. And Atherton, J.C. (2021) 'The Spectrum of Helicobacter-Mediated Diseases', Annual Review of Pathology: Mechanisms of Disease 16:1, 123-144
• Kaneko, K., and Robinson, K. (2021) 'Analysis of T Cell Responses to Helicobacter pylori Infection', Methods Mol Biol. 2283, 215-223.

Felicity Rose

• Burroughs, L, MH Amer, M Vassey, B Koch, GP Figueredo, B Mukonoweshuro, P Mikulskis, A Vasilevich, S Vermeulen, IL Dryden, DA Winkler, AM Ghaemmaghami, FRAJ Rose, J de Boer, MR Alexander.  (2021) Discovery of synergistic material-topography combinations to achieve immunomodulatory osteoinductive biomaterials using a novel in vitro screening method: The chemotopochip.  Biomaterials 271, 120740.
• Amer, MH, M Alvarez-Paino, J mclaren, F Pappalardo, S Trujillo, JQ Wong, S Shrestha, S Abdelrazig, LA Stevens, JB Lee, DH Kim, C González-García, D Needham, M Salmerón-Sánchez, KM Shakesheff, MR Alexander, C Alexander, FRAJ Rose. (2021) Designing topographically textured microparticles for induction and modulation of osteogenesis in mesenchymal stem cell engineering. Biomaterials 266, 120450.
• Dooley, M, J mclaren, FRAJ Rose, I Notingher.  (2020) Investigating the feasibility of spatially offset Raman spectroscopy for in‐vivo monitoring of bone healing in rat calvarial defect models. Journal of Biophotonics 13 (10), e202000190.
• Prina, E, MH Amer, L Sidney, M Tromayer, J Moore, R Liska, M Bertolin, S Ferrari, A Hopkinson, HS Dua, J Yang, RD Wildman, FRAJ Rose. (2020) Bioinspired Precision Engineering of Three‐Dimensional Epithelial Stem Cell Microniches.  Advanced Biosystems 4 (6), 2000016.
• He, Y, R Foralosso, GF Trindade, A Ilchev, L Ruiz‐Cantu, EA Clark, S Khaled, RJM Hague, CJ Tuck, FRAJ Rose, G Mantovani, DJ Irvine, CJ Roberts, RD Wildman. (2020) A Reactive Prodrug Ink Formulation Strategy for Inkjet 3D Printing of Controlled Release Dosage Forms and Implants. Advanced Therapeutics 3 (6), 1900187.
• Ruiter, FAA, LE Sidney, KL Kiick, JI Segal, C Alexander, FRAJ Rose. (2020) The electrospinning of a thermo-responsive polymer with peptide conjugates for phenotype support and extracellular matrix production of therapeutically relevant mammalian cells. Biomaterials Science 8 (9), 2611-2626.

Ian Sayers

• O'Loughlin J, Hall RJ, Bhaker S, Portelli MA, Henry A, Pang V, Bates DO, Sharp TV, Sayers I. (2021) Extended lifespan of bronchial epithelial cells maintains normal cellular phenotype and transcriptome integrity. ERJ Open Res. 2021 Jan 18;7(1):00254-2020. DOI: 10.1183/23120541.00254-2020. Ecollection 2021 Jan.
• Heijink IH, Kuchibhotla VNS, Roffel MP, Maes T, Knight DA, Sayers I, Nawijn MC. Epithelial cell dysfunction, a major driver of asthma development. Allergy. 2020 Aug;75(8):1902-1917. DOI: 10.1111/all.14421. Epub 2020 Jun 16.
• Kc B, Mahapatra PS, Thakker D, Henry AP, Billington CK, Sayers I, Puppala SP, Hall IP. Proinflammatory Effects in Ex Vivo Human Lung Tissue of Respirable Smoke Extracts from Indoor Cooking in Nepal. Ann Am Thorac Soc. 2020 Jun;17(6):688-698. DOI: 10.1513/annalsats.201911-827OC.
• Ketelaar ME, Portelli MA, Dijk FN, Shrine N, Faiz A, Vermeulen CJ, Xu CJ, Hankinson J, Bhaker S, Henry AP, Billington CK, Shaw DE, Johnson SR, Benest AV, Pang V, Bates DO, Pogson ZEK, Fogarty A, mckeever TM, Singapuri A, Heaney LG, Mansur AH, Chaudhuri R, Thomson NC, Holloway JW, Lockett GA, Howarth PH, Niven R, Simpson A, Tobin MD, Hall IP, Wain LV, Blakey JD, Brightling CE, Obeidat M, Sin DD, Nickle DC, Bossé Y, Vonk JM, van den Berge M, Koppelman GH, Sayers I, Nawijn MC.
• Phenotypic and functional translation of IL33 genetics in asthma. J Allergy Clin Immunol. 2021 Jan;147(1):144-157. DOI: 10.1016/j.jaci.2020.04.051. Epub 2020 May 19.
• Portelli MA, Dijk FN, Ketelaar ME, Shrine N, Hankinson J, Bhaker S, Grotenboer NS, Obeidat M, Henry AP, Billington CK, Shaw D, Johnson SR, Pogson ZE, Fogarty A, mckeever TM, Nickle DC, Bossé Y, van den Berge M, Faiz A, Brouwer S, Vonk JM, de Vos P, Brandsma CA, Vermeulen CJ, Singapuri A, Heaney LG, Mansur AH, Chaudhuri R, Thomson NC, Holloway JW, Lockett GA, Howarth PH, Niven R, Simpson A, Blakey JD, Tobin MD, Postma DS, Hall IP, Wain LV, Nawijn MC, Brightling CE, Koppelman GH, Sayers I. Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium. JCI Insight. 2020 Apr 23;5(8):e132446. DOI: 10.1172/jci.insight.132446.
• Allen RJ, Guillen-Guio B, Oldham JM, Ma SF, Dressen A, Paynton ML, Kraven LM, Obeidat M, Li X, Ng M, Braybrooke R, Molina-Molina M, Hobbs BD, Putman RK, Sakornsakolpat P, Booth HL, Fahy WA, Hart SP, Hill MR, Hirani N, Hubbard RB, mcanulty RJ, Millar AB, Navaratnam V, Oballa E, Parfrey H, Saini G, Whyte MKB, Zhang Y, Kaminski N, Adegunsoye A, Strek ME, Neighbors M, Sheng XR, Gudmundsson G, Gudnason V, Hatabu H, Lederer DJ, Manichaikul A, Newell JD Jr, O'Connor GT, Ortega VE, Xu H, Fingerlin TE, Bossé Y, Hao K, Joubert P, Nickle DC, Sin DD, Timens W, Furniss D, Morris AP, Zondervan KT, Hall IP, Sayers I, Tobin MD, Maher TM, Cho MH, Hunninghake GM, Schwartz DA, Yaspan BL, Molyneaux PL, Flores C, Noth I, Jenkins RG, Wain LV. Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2020 Mar 1;201(5):564-574. DOI: 10.1164/rccm.201905-1017OC.

Claire Seedhouse

• Thompson, J.L., Downie Ruiz Velasco, A,, Lister, M., Cardall, A., Howson-Wells, H.C., Tarbox, R., Richardson, J., Clarke, G., Fleming, V.M., Khakh, M., Sloan, T., Duckworth, N., Walsh, S., Denning, C., mcclure, C.P., Benest, A.V., Seedhouse, C.H. (2021). ‘Comparative effects of viral transport medium heat inactivation upon downstream SARS-cov-2 detection in patient samples’, J. Med. Microbiol. Online ahead of print DOI: 10.1099/jmm.0.001301
• Bailey, G.D., Doolan, L., Baskar, A., Smith, L.C., Seedhouse, C.H. (2020) ‘Preferential transcription of the mutated allele in NPM1 mutated acute myeloid leukaemia’, Sci. Rep., 10, 17695. DOI: 10.1038/s41598-020-73782-x
• Grundy, M., Al-Kaisi, F., Cull, J., Williams, C., Smith, D., Seedhouse, C.H. (2020) ‘A same day assay predicts apoptotic response to combined BCL-2 and MCL-1 BH3 mimetic targeting in multiple myeloma cells’, E. J. Haem., 2, 40-47. DOI: 10.1002/jha2.133
• Almasmoum, H., Seedhouse, C., Winkler, G.S. (2020) ‘Frequent loss of BTG1 activity and impaired interactions with the Caf1 subunit of the Ccr4-Not deadenylase in non-Hodgkin lymphoma’, Leuk. Lymphoma, 62, 281-290. DOI: 10.1080/10428194.2020.1827243
• Alhuthali, H.M., Bradshaw, T.D., Lim, K.H., Tam, K.S., Seedhouse, C.H. (2020) ‘The natural alkaloid Jerantinine B has activity in acute myeloid leukaemia cells through a mechanism involving c-Jun’, BMC Cancer 20, 629. DOI: 10.1186/s12885-020-07119-2

Abdolrahman Shams-Nateri

• Almozyan S, Coulton J, Babaei-Jadidi R, and NATERI AS (2021).’ FLYWCH1, a Multi-Functional Zinc Finger Protein Contributes to the DNA Repair Pathway’. Cells., In press
• Babaei-Jadidi R, Dongre A, Miller S, Castellanos Uribe M, Stewart ID, Thompson ZM, Nateri AS, Bradding P, May ST, Clements D, and Johnson SR (2021). ‘Mast cell tryptase release contributes to disease progression in lymphangioleiomyomatosis’. American Journal of Respiratory And Critical Care Medicine., In press.
• Almusawi S, Ahmed M, and Nateri AS (2021). 'Understanding cell-cell communication and signaling in the colorectal cancer microenvironment'. Clin Transl Med., 11(2):e308
• Kashfi H, Jinks N, and Nateri AS (2020). 'Generating and Utilizing Murine Cas9-Expressing Intestinal Organoids for Large-Scale Knockout Genetic Screening'. Methods Mol Biol., 2171:257-269.
• AHMED M, JINKS N, BABAEI-JADIDI R, KASHFI H, CASTELLANOS-URIBE M, MAY ST, MUKHERJEE A and NATERI AS (2020). ‘Repurposing Antibacterial AM404 as a Potential Anticancer Drug for Targeting Colorectal Cancer Stem-Like Cells’. Cancers (Basel)., 12(1):106.
• Raposo TP, Alfahed A, Nateri AS, and Ilyas M. (2020). 'Tensin4 (TNS4) is upregulated by Wnt signalling in adenomas in multiple intestinal neoplasia (Min) mice'. Int J Exp Pathol., 101(3-4):80-86.

Stuart Smith

• Vasey C, Cavanagh RJ, Taresco V, Moloney C, Smith SJ, Rahman R, Alexander C Polymer pro-drug nanoparticles for sustained release of cytotoxic drugs evaluated in patient derived glioblastoma cell lines and in situ gelling formations Pharmaceutics 2021 13:208
• Fountain DM, Piper RJ, Poon MTC,…Smith SJ, Thomson S, Lau JY, Watts C, Jenkinson MD Covid neuroonc: a UK multicentre, prospective cohort study of the impact of the COVID-19 pandemic on the neuro-oncology service. Neuro-Oncology Adv 2021
• Griffin M, Khan R, Basu S, Smith SJ Ion channels as therapeutic targets in high grade gliomas  Cancers 2020 12:3068 DOI:10.3390/cancers12103068
• Mccrorie P, Mistry J, Taresco V….Smith SJ, Marlow M, Rahman R  Etoposide and Olaparib polymer coated nanoparticles within a bioadhesive sprayable hydrogel for post-surgical localised delivery to brain tumours Eur J Pharmaceutics and Biopharm 2020 157:108-120
• Smith SJ, Rowlinson J, Estevez-Cebrero M, Onion D, Ritchie A, Clarke P, Wood K, Diksin M, Lourdusamy A, Grundy RG, Rahman R  Metabolism based isolation of invasive glioblastoma cells with specific gene signatures and tumorigenic potential Neuro-Oncology Adv 2020 DOI: 10.1093/noajnl/vdaa087
• Price S, Joannides A, Plaha P, … Smith SJ, … Jenkinson M Impact of COVID-19 Pandemic on Surgical Neuro-oncology Multi-Disciplinary Team Decision Making – A National Survey (COVID-CNSMDT Study) BMJ Open 2020 Aug 16;10(8):e040898. DOI: 10.1136/bmjopen-2020-040898.
• Mccrorie P, Vasey CE, Smith SJ, Marlow M, Alexander C, Rahman R Biomedical engineering approaches to enhance therapeutic delivery for malignant gliomas. J Con Rel 2020 doi.org/10.1016/j.jconrel.2020.11.022
• Morris B, Curtin L, … Smith SJ… Owen MR Identifying the spatial and temporal dynamics of molecularly-distinct glioblastoma subpopulations. Mathematical Biosciences and Engineering 2020 17(5): 4905-4941
• Yao A, Storr SJ,…Smith SJ, Grundy RG, Paine S, Martin SG Thioredoxin system protein expression is associated with poor clinical outcome in adult and paediatric gliomas and medulloblastomas. Mol Neurobiol 2020 DOI:10.1007/s12035-020-01928-z
• Aly A, Smith F, Glancz L,…Boam S, Smith SJ IDH1 status and venous thromboembolism in glioma patients JSO DOI:10.31487/j.JSO.2019.04.04
• Vasilev A, Sofi R, Rahman R, Smith SJ, Teschemacher AG, Kasparov S Using light for therapy of glioblastoma multiforme (GBM). Brain Sci 2020, 10,75; DOI:10.3390/brainsci10020075
• Greco C, Taresco V,…Smith SJ… Schenone S Development of Pyrazolo[3,4-d]pyrimidine kinase inhibitors as potential clinical candidates for glioblastoma multiforme. ACS Medicinal Chemistry Letters 2020 11(5): 657-663
• Haley M, Kumaria A, Lenthall R, mcconachie N, Smith SJ, Dow G Coughing on the coil; a case report and literature review of eight cases of endovascularly treated ICA pseudoaneurysms with coil migration into the oropharynx. BJNS 2020 DOI: 10.1080/02688697.2020.1716944

Philippe Soucaille

• YOO M, NGUYEN NP and SOUCAILLE P (2020) Trends in systems biology for the analysis and engineering of Clostridium acetobutylicum. Trends in Microbiol.  28: 118-140
• JIN S, BAE J, SONG Y, PEARCY N, SHIN J, KANG S, MINTON NP, SOUCAILLE P, and CHO BK (2020) Synthetic Biology on Acetogenic Bacteria for Highly Efficient Conversion of C1 Gases to Biochemicals. Int. J. Mol. Sci.. 21: 7639
• TOMI-ANDRINO C, NORMAN R, MILLAT T, SOUCAILLE P, WINZER K, BARRETT DA, KING J, and KIM DH (2021) Physicochemical and metabolic constraints for thermodynamics-based stoichiometric modelling under mesophilic growth conditions. PLOS Comput. Biol. 17: e1007694
• WILDING STEELE T,  RAMETTE Q, JACOTTIN P, and SOUCAILLE P (2021) Improved CRISPR/cas9 tools for the rapid metabolic engineering of Clostridium acetobutylicum. Int. J. Mol. Sci.. 22: 3704.

Panos Soultanas

• JENKINS, T., NORTHALL, S., PTCHELKINE, D., BETTS, H., CUBBON, A., LEVER, R., TARESCO, V., COOPER, C., MCHUGH, P., SOULTANAS, P. And BOLT, E. (2021). The helq human DNA repair helicase utilizes a PWI-like domain for DNA loading through interaction with RPA, triggering DNA unwinding by the helq helicase core. Nucleic Acids Research Cancer. (In Press).

Ian Spendlove

• Soliman C, Guy AJ, Chua JX, Vankemmelbeke M, mcintosh RS, Eastwood S, Truong VK, Elbourne A, Spendlove I, Durrant LG, Ramsland PA.. (2020) ‘Molecular and structural basis for Lewis glycan recognition by a cancer-targeting antibody’.  Biochem J. Sept 18.  477(17):
• Aram J, Frakich N, Morandi E, Alrouji M, Samaraweera A, Onion D, Spendlove I, Colombo SL, Tanasescu R, Gran B, Constantinescu CS. (2020). ‘Increased IL-2 and Reduced TGF-β Upon T-Cell Stimulation are Associated with GM-CSF Upregulation in Multiple Immune Cell Types in Multiple Sclerosis’. Biomedicines. Jul 18;8(7):226.
• Vankemmelbeke M, mcintosh RS, Chua JX, Kirk T, Daniels I, Patsalidou M, Moss R, Parsons T, Scott D, Harris G, Ramage JM, Spendlove I, Durrant LG. (2020) ‘Engineering the Human Fc Region Enables Direct Cell Killing by Cancer Glycan-Targeting Antibodies without the Need for Immune Effector Cells or Complement’. Cancer Res. Aug 15;80(16):3399-3412. 
• Soliman C, Chua JX, Vankemmelbeke M, mcintosh RS, Guy AJ, Spendlove I, Durrant LG, Ramsland PA. (2020) 'The terminal sialic acid of stage-specific embryonic antigen-4 has a crucial role in binding to a cancer-targeting antibody’ J Biol Chem. Jan 24;295(4):1009-1020.

Michael Stocks

• Garces, A. E.; Al-Hayali, M.; Lee, J. B.; Li, J.; Gershkovich, P.; Bradshaw, T. D.; Stocks, M. J. (2020) ‘Codrug Approach for the Potential Treatment of EML4-ALK Positive Lung Cancer.’, ACS Medicinal Chemistry Letters. American Chemical Society, 11(3), pp. 316–321. DOI: 10.1021/acsmedchemlett.9b00378.
• Grossman, S.; Soukarieh, F.; Richardson, W.; Liu, R.; Mashabi, A.; Emsley, J.; Williams, P.; Camara, M.; Stocks, M. J. (2020) ‘Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator pqsr.’, European Journal of Medicinal Chemistry. Elsevier Masson SAS, 208, p. 112778. DOI: 10.1016/j.ejmech.2020.112778.
• Qin, C.; Feng, W.; Chu, Y. J.; Lee, J. B.; Berton, M.; Bettonte, S.; Teo, Y. Y.; Stocks, M. J.; Fischer, P. M.; Gershkovich, P. (2020) ‘Development and validation of a cost-effective and sensitive bioanalytical HPLC-UV method for determination of lopinavir in rat and human plasma.’, Biomedical Chromatography. John Wiley & Sons Ltd., p. Ahead of Print. DOI: 10.1002/bmc.4934.
• Qin, C.; Chu, Y.; Feng, W.; Fromont, C.; He, S.; Ali, J.; Lee, J. B.; Zgair, A.; Berton, M.; Bettonte, S.; Liu, R.; Yang, L.; Monmaturapoj, T.; Medrano-Padial, C.; Ugalde, A. A. R.; Vetrugno, D.; Ee, S. Y.; Sheriston, C.; Wu, Y.; Stocks, M. J.; Fischer, P. M.; Gershkovich, P. (2020) ‘Targeted delivery of lopinavir to HIV reservoirs in the mesenteric lymphatic system by lipophilic ester prodrug approach.’, Journal of Controlled Release. Elsevier B.V., p. Ahead of Print. DOI: 10.1016/j.jconrel.2020.10.036.
• Sou, T.; Soukarieh, F.; Williams, P.; Stocks, M. J.; Cámara, M.; Bergström, C. A. S. (2020) ‘Model-Informed Drug Discovery and Development in Pulmonary Delivery: Biopharmaceutical Pharmacometric Modeling for Formulation Evaluation of Pulmonary Suspensions’, ACS Omega. DOI: 10.1021/acsomega.0c03004.
• Soukarieh, F. Et al. (2020) ‘Hit Identification of New Potent pqsr Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa’, Frontiers in Chemistry, 8, p. 204. DOI: 10.3389/fchem.2020.00204.

Sarah Storr

• Abdullah NA, Inman M, Moody CJ, Storr SJ, Martin SG (2021). 'Cytotoxic and radiosensitising effects of a novel thioredoxin reductase inhibitor in breast cancer'. Invest New Drugs DOI: 10.1007/s10637-021-01106-5
• Martin SG, Zhang S, Yang S, Saidy B, Deen S, Storr SJ (2020). 'Dopamine and camp-regulated phosphoprotein 32kda (DARPP-32), protein phosphatase-1 and cyclin-dependent kinase 5 expression in ovarian cancer'. J Cell Mol Med 24: 9165-9175
• Yao A, Storr SJ, Al-Hadyan K, Rahman R, Smith S, Grundy R, Paine S, Martin SG (2020). 'Thioredoxin system protein expression is associated with poor clinical outcome in adult and paediatric gliomas and medulloblastomas'. Mol Neurobiol 57: 2889-2901
• Saidy B, Rakha E, Green AR, Ellis, Martin S, Storr S (2020). 'Retrospective assessment of cyclin-dependent kinase 5 protein and mrna expression in breast cancer and its association with patient survival'. J Cell Mol Med 24: 6263-6271

Neil Thomas

• SAFO, L., ABDELRAZIG, S., GROSSE-HONEBRINK, A., MILLAT, T., HENSTRA, A. M., NORMAN, R., THOMAS, N. R., WINZER, K., MINTON, N., KIM, D.-H. And BARRETT, D, (2021). Quantitative Bioreactor Monitoring of Intracellular Bacterial Metabolites in Clostridium autoethanogenum using Liquid Chromatography-Isotope Dilution Mass Spectrometry ACS Omega. (In Press.)
• CHETTY, S., ARMSTRONG, T, DREWE, W.C., DREWE, W.C., DE MATTEIS, C.I., EVANGELOPOULOS, D., BHAKTA, S. And THOMAS, N.R., (2021) New inha Inhibitors Based on Expanded Triclosan and Di-Triclosan Analogues to Develop a New Treatment for Tuberculosis Pharmaceuticals. 14(4), 361.
• BOUZINAB K, SUMMERS HS, STEVENS MFG, MOODY CJ, THOMAS NR, GERSHKOVICH P, WESTON N, ASHFORD MB, BRADSHAW TD and TURYANSKA L, (2020). Delivery of Temozolomide and N3-Propargyl Analog to Brain Tumors Using an Apoferritin Nanocage. ACS applied materials & interfaces. 12(11), 12609-12617.
• ARMSTRONG, T., LAMONT, M., LANNE, A., ALDERWICK, L. J. And THOMAS, N.R., (2020). Inhibition of Mycobacterium tuberculosis inha: Design, synthesis and evaluation of new di-triclosan derivatives. Bioorganic & medicinal chemistry. 28(22), 115744.
• HARVEY, D., BRAY, G., ZAMBERLAN, F., AMER, M., GOODACRE, S. L. And THOMAS, N. R., (2020). Cyclo(rgdfk) Functionalized Spider Silk Cell Scaffolds: Significantly Improved Performance in Just One Click Macromol. Bioscience, 20(12), 2000255.

Alexander Thompson

• Smith J.S., Lappin K.M., Craig S.G., Liberante F.G., Crean C.M., mcdade S.S., Thompson A., Mills KI and Savage K.I. (2020). 'Chronic loss of STAG2 leads to altered chromatin structure contributing to de-regulated transcription in AML', J. Transl. Med.,18(1):339-357.
• Ashworth J.C., Thompson J.L., James J.R., Slater C.E., Pijuan-Galitó S., Lis-Slimak K., Holley R.J., Meade K.A., Thompson A., Arkill K.P., Tassieri M., Wright A.J., Farnie G. And Merry C.L.R. (2020). 'Peptide gels of fully-defined composition and mechanics for probing cell-cell and cell-matrix interactions in vitro'. Matrix Biol. 85-86:15-33.
• Bhagwan J.R., Collins E., Mosqueira D., Bakar M., Johnson B.B., Thompson A., Smith J.G.W. and Denning C. 'Variable expression and silencing of CRISPR-Cas9 targeted transgenes identifies the AAVS1 locus as not an entirely safe harbour'. F1000Res. 2019 Nov 12;8:1911. Published online 2020 Jul 10. DOI: 10.12688/f1000research.19894.2.

Lisa White

• Black, C., Kanczler, J.M., de Andrés, M.C., White, L.J., Savi, F.M., Bas, O., Saifzadeh, S., Henkel, J., Zannettino, A., Gronthos, S., Woodruff, M.A., Hutmacher, D.W., Oreffo, R.O.C. (2020). 'Characterisation and evaluation of the regenerative capacity of Stro-4+ enriched bone marrow mesenchymal stromal cells using bovine extracellular matrix hydrogel and a novel biocompatible melt electro-written medical-grade polycaprolactone scaffold,' Biomaterials, 247, 119998.
• Quijano, L.M., Naranjo, J.D., El-Mossier, S.O., Turner, N.J., Molina, C.P., Bartolacci, J., Zhang, L., White, L., Li, H. Badylak, S.F. (2020). 'Matrix-bound nanovesicles: The effects of isolation method upon yield, purity, and function', Tissue Engineering - Part C: Methods; 26 (10), 528-540.

Huw Williams

• Al-sandaqchi, A.T., Marsh, V., Williams, H.E.L., Stevenson, C.W., Elsheikha, H.M. (2020) Structural, Functional, and Metabolic Alterations in Human Cerebrovascular Endothelial Cells during Toxoplasma gondii Infection and Amelioration by Verapamil In Vitro. Microorganisms 8, 1386
• Ciszewski, L., Lu-Nguyen, N., Slater, A., Brennan, A., Williams, H.E.L., Dickson, G., Searle, M.S., Popplewell, L. (2020) G-quadruplex ligands mediate downregulation of DUX4 expression. Nucleic Acids Research 48, 4179–4194
• Furse, S., Fernandez-Twinn, D.S., Jenkins, B., Meek, C.L., Williams, H.E.L., Smith, G.C.S., Charnock-Jones, D.S., Ozanne, S.E., Koulman, A. (2020) A high-throughput platform for detailed lipidomic analysis of a range of mouse and human tissues. Anal Bioanal Chem 412, 2851–2862.
• Furse, S., Watkins, A.J., Hojat, N., Smith, J., Williams, H.E.L., Chiarugi, D., Koulman, A. (2021) Lipid Traffic Analysis reveals the impact of high paternal carbohydrate intake on offsprings’ lipid metabolism. Communications Biology 4, 1–12
• Furse, S., Williams, H., Watkins, A., Virtue, S., Vidal-Puig, A., Charalambous, M., Koulman, A. (2021)  A Pipeline for Making 31P NMR Accessible for Small- and Large-Scale Lipidomics Studies. (In Press -https://doi.org/10.26434/chemrxiv.14053976.v1 )
• Griffiths, R.C., Smith, F.R., Long, J.E., Williams, H.E.L., Layfield, R., Mitchell, N.J., (2021) Site-Selective Modification of Peptides and Proteins via Interception of Free-Radical-Mediated Dechalcogenation. Angewandte Chemie 132, 23867–23875.
• Valentine, A.J., Geer, A.M., Taylor, L.J., Teale, A.M., Wood, K.E., Williams, H.E.L., Lewis, W., Argent, S.P., mcmaster, J., Kays, D.L. (2021) Structural and electronic studies of substituted m-terphenyl lithium complexes. Dalton Trans. 50, 722–728.

Paul Williams

• Jordana-Lluch, E., Garcia, V., Kingdon, A., Singh, N., Alexander, C., Williams, P. And Hardie, K. R. (2020). ‘A simple polymicrobial biofilm keratinocyte colonization model for exploring interactions between commensals, pathogens and antimicrobials’. Front. Microbiol. 11, 291. DOI: 10.3389/fmicb.2020.00291
• Barzan, G., Sacco, A., Mandrile, L. Giovannozzi, A.M., Brown, J., Portesi, C., Alexander, M.R., Williams, P. Hardie, K. And Rossi, A.M. (2020). ‘New frontiers against antibiotic resistance: A Raman-based approach for rapid detection of bacterial susceptibility and biocide-induced antibiotic cross-tolerance’. Sens. Actuators B Chem 309:127774; doi.org/10.1016/j.snb.2020.127774
• Soukarieh, F., Liu, R., Romero, M., Roberston, S. N., Richardson, W., Lucanto, S., Oton, E. V., Qudus, N. R., Mashabi, A., Grossman, S., Ali, S., Sou, T., Kukavica-Ibrulj, I., Levesque, R. C., Bergström, C., Halliday, N., Mistry, S. N., Emsley, J., Heeb, S., Williams, P., Cámara M.  And Stocks, M. J. (2020). ‘Hit identification of new potent pqsr antagonists as inhibitors of quorum sensing in planktonic and biofilm grown Pseudomonas aeruginosa’. Front. Chem. 8, 204. Doi.org/10.3389/fchem.2020.00204
• Vassey, M. J., Figueredo, G. P., Scurr, D. J., Vasilevich, A. S., Vermeulen, S., Carlier, A., Luckett, J., Beijer, N., Williams, P., Winkler, D. A., de Boer, J., Ghaemmaghami, A. M., and Alexander, M. R. (2020). ‘Immune modulation by design: using topography to control human monocyte attachment and macrophage differentiation.’ Adv. Sci. 7, 1903392. Doi.org/10.1002/advs.201903392
• Zhang, J., Brown, J., Scurr, D. J., Bullen, A., maclellan-Gibson, K., Williams, P., Alexander, M. R., Hardie, K. R., Gilmore, I. S., and Rakowska, P. D. (2020). ‘Cryo-orbisims for 3D molecular imaging of a bacterial biofilm in its native state.’ Anal. Chem. 92, 9008–9015. Https://doi.org/10.1021/acs.analchem.0c01125
• Dundas, A. A., Cuzzucoli, V., Haas, S., Dubern, J.‐F., Latif, A., Romero, M., Sanni, O., Ghaemmaghami, A. M., Williams, P., Alexander, M. R., Wildman, R. And Irvine, D. J., (2020). ‘Achieving microparticles with cell‐instructive surface chemistry by using tunable co‐polymer surfactants’. Adv. Funct. Mater. 30, 2001821. Doi.org/10.1002/adfm.202001821
• Blower, I., Tong, C., Sun, X., Murray, E., Luckett, J., Chan, W., Williams, P. And Hill, P. (2020). ‘Gaussia luciferase as a reporter for quorum sensing in Staphylococcus aureus’. Sensors 20, 4305. Doi.org/10.3390/s20154305
• Singh, T., Hook, A. L., Luckett, J., Maitz, M. F., Sperling, C., Werner, C., Davies, M. C., Irvine, D. J., Williams, P. And Alexander, M. R. (2020). ‘Discovery of hemocompatible bacterial biofilm-resistant copolymers’. Biomaterials, 260, 120312; DOI: 10.1016/j.biomaterials.2020.120312
• Grossman, S., Soukarieh, F., Richardson, W., Liu, R., Mashabi, A., Emsley, J., Williams, P., Cámara, M. And Stocks, M. J. (2020). ‘Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator pqsr’. European journal of medicinal chemistry, 208, 112778; doi.org/10.1016/j.ejmech.2020.112778
• López-Martín, M., Dubern, J. F., Alexander, M. R., & Williams, P. (2021). Abam Regulates Quorum Sensing, Biofilm Formation, and Virulence in Acinetobacter baumannii. Journal of bacteriology, 203(8), e00635-20. Doi.org/10.1128/JB.00635-20.
• Carabelli ,A.M,. Isgro, M., Sanni O, Figueredo, G.P., Winkler, D.A., Burroughs L,. Blok, A.J., Dubern, J.-F., Pappalardo, F., Hook, A.L., Williams, P. And Alexander, M.R. (2020) 'Single cell tracking on polymer microarrays reveals the impact of surface chemistry on Pseudomonas aeruginosa twitching speed and biofilm development'. ACS Applied Bio Materials 3: 8471–848.doi-org.ezproxy.nottingham.ac.uk/10.1021/acsabm.0c00849

Klaus Winzer

• Tomi-Andrino, C., Norman, R., Millat T., Soucaille, P., Winzer, K., Barrett, D. A., King, J., and Kim, D.-H. (2021). 'Physicochemical and metabolic constraints for thermodynamics-based stoichiometric modelling under mesophilic growth conditions', plos Comput.l Biol. 17, e1007694.
• Safo,L., Abdelrazig, S., Grosse-Honebrink, A., Millat, T., Henstra, A. M., Norman, R., Thomas, N. R., Winzer, K., Minton, N. P., Kim, D.-H., and Barrett, D. A. (2021). 'Quantitative bioreactor monitoring of intracellular bacterial metabolites in Clostridium autoethanogenum using liquid chromatography-isotope dilution mass spectrometry', ACS Omega. (In Press.).
• Kotte ,A.-K., Severn, O., Bean, Z., Schwarz, K., Minton, N.P., and Winzer, K. (2020). 'RRNPP-type quorum sensing affects solvent formation and sporulation in Clostridium acetobutylicum', Microbiology 166, 579–592.

Jing Yang

• LAURA RUIZ-CANTU, ANDREW GLEADALL, CALLUM FARIS, JOEL SEGAL, KEVIN SHAKESHEFF and JING YANG, 2020. Multi-material 3D bioprinting of porous constructs for cartilage regeneration Materials Science & Engineering C.
• PRINA, ELISABETTA, AMER, MAHETAB H, SIDNEY, LAURA, TROMAYER, MAXIMILIAN, MOORE, JONATHAN, LISKA, ROBERT, BERTOLIN, MARINA, FERRARI, STEFANO, HOPKINSON, ANDREW, DUA, HARMINDER, YANG, JING, WILDMAN, RICKY and ROSE, FELICITY R A J, 2020. Bioinspired Precision Engineering of Three-Dimensional Epithelial Stem Cell Microniches. Advanced biosystems. E2000016
• LARA FIGUEIREDO, CATHERINE LE VISAGE, PIERRE WEISS and JING YANG, 2020. Quantifying Oxygen Levels in 3D Bioprinted Cell-Laden Thick Constructs with Perfusable Microchannel Networks Polymers. 12(6), 1260
• HODA M. ELTAHER, FATIMA E. ABUKUNNA, LAURA RUIZ-CANTU, ZACK STONE, JING YANG and JAMES E. DIXON, 2020. Human-scale Tissues with Patterned Vascular Networks by Additive Manufacturing of Sacrificial Sugar-Protein Composites Acta Biomaterialia.
• ARUNA PRASOPTHUM, ZEXING DENG, ILYAS M. KHAN, ZHANHAI YIN, BAOLIN GUO and JING YANG, 2020. Three dimensional printed degradable and conductive polymer scaffolds promote chondrogenic differentiation of chondroprogenitor cells Biomaterials Science.
• OMAR A. HAMID, HODA M. ELTAHER, VIRGINIE SOTTILE and JING YANG, 2020. 3D bioprinting of a stem cell-laden, multi-material tubular composite: An approach for spinal cord repair Materials Science and Engineering: C. 111707
• DUAN, HUYANG, CAO, CHUANLIANG, WANG, XIAOLEI, TAO, JUN, LI, CHEN, XIN, HONGBO, YANG, JING, SONG, YULIN and AI, FANRONG, 2020. Magnesium-alloy rods reinforced bioglass bone cement composite scaffolds with cortical bone-matching mechanical properties and excellent osteoconductivity for load-bearing bone in vivo regeneration. Scientific reports. 10(1), 18193

Ying Zhang

• Grosse-Honebrink A, Little TL, Bean Z, Minton NP, Heldt D, Cornock RHM, Winzer K, Minton NP, Green E and Zhang Y. (2021) Development of Clostridium saccharoperbutylacetonicum as a whole cell biocatalyst for production of pure (R)-1,3-butanediol. Front. Bioeng. Biotechnol., DOI: 10.3389/fbioe.2021.659895
• Rumah BL, Stead CE, Claxton Stevens BH, Minton NP, Grosse-Honebrink A, Zhang Y.  (2021) Isolation and characterisation of Methylocystis spp. For poly-3-hydroxybutyrate production using waste methane feedstocks. AMB Express., Jan 6;11(1):6. DOI: 10.1186/s13568-020-01159-4.