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Welcome to the Biodiscovery Institute's Good News Hub

At the Biodiscovery Institute, we take immense pride in shining a spotlight on the remarkable developments unfolding within our Institute. This platform serves as a testament to our commitment to pioneering research, fostering collaboration, and nurturing a positive research culture. From scientific breakthroughs and cutting-edge advancements to the personal anecdotes and triumphs of our peers, the Good News hub is a celebration of the extraordinary journey we are undertaking. Join us in exploring the brighter side of science!

 

 

Featured News

A hand holding a pen, drawing a computer generate graphic of ovaries
University of Nottingham establishes new £4 million ovarian cancer research centre

A new research centre to drive forward the latest advancements to tackle ovarian cancer is to be launched at the University of Nottingham.

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Gloved hand pipetting liquid from well plate
University of Nottingham receives £4.4m funding for world-class bioscience research programme

A research team led by the University of Nottingham has been selected as one of four that will receive a share of £18 million to pursue transformational bioscience research programmes.

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Biodiscovery Institute building exterior
BDI team part of £70M programme in health data science

The digital research service is helping Dr. Philip Quinlan in continuing to develop national federated analytics capabilities

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Announcements

Children with Cancer UK funds brain tumour research led by Dr. Beth Coyle

Children with Cancer UK have awarded £349,209.83 to a multidisciplinary team led by Dr Beth Coyle who will be 'Establishing tumour microenvironment models of paediatric brain tumours'.

Emad Rakha to receive 2024 ISBP Larry Norton Award of Excellence in Breast Pathology

Emad Rakha has been invited to receive the 2024 International Society of Breast Pathology (ISBP) Larry Norton Award of Excellence in Breast Pathology. The Larry Norton Award, established in 2018, is presented annually to recognise the career and achievements of distinguished individuals who have made outstanding contributions to the field of breast pathology. The award and lecture will be presented at the ISBP Companion meeting during the United States and Canadian Academy of Pathology (USCAP) annual meeting in 2024.

BDI Co-Is awarded BBSRC Equipment grants 

Multiphoton microscope - £1.35million awarded - lead by Kim Chisolm from QMC Life Sciences

Lumicks C-Trap Optical Tweezers - £1.15million awarded - lead by Claire Friel from QMC Life Science

Thank you to those from BDI who were involved in successfully securing this funding and allowing the Institute to benefit from these valuable tools moving forward.

 

 

Recent News

Noninvasive Monitoring of Palmitoyl Hexapeptide-12 in Human Skin Layers: Mechanical Interaction with Skin Components and Its Potential Skincare Benefits

Noninvasive Monitoring of Palmitoyl Hexapeptide-12 in Human Skin Layers: Mechanical Interaction with Skin Components and Its Potential Skincare Benefits

Description
A new study by BDI Researchers from the UoN Faculty of Science explores a popular anti-aging peptide, its ability to strengthen the skin barrier, and establishes a methodological benchmark for measuring the effects of cosmetic peptides on skin mechanics.
Date:
07 March 2025
A rapid genome-proteome approach to identify rate-limiting steps in the butyrate production pathway in probiotic Clostridium butyricum, CBM588

A rapid genome-proteome approach to identify rate-limiting steps in the butyrate production pathway in probiotic Clostridium butyricum, CBM588

Description
BDI post-doc researchers have found a way to enhance butyrate production, a key compound linked to gut health.Using a novel rapid genome-proteome approach, they identified enzymes that limit butyrate production and successfully increased output by over-expressing key genes. This breakthrough could lead to stronger probiotics with greater health benefits.
Date:
07 March 2025
Wnt/GSK-3β mediates posttranslational modifications of FLYWCH1 to regulate intestinal epithelial function and tumorigenesis in the colon

Wnt/GSK-3β mediates posttranslational modifications of FLYWCH1 to regulate intestinal epithelial function and tumorigenesis in the colon

Description
A recent study by BDI's School of Medicine collegues uncovers a novel regulatory mechanism of ß-catenin—a key player in Wnt signalling—distinguishing its role in healthy tissue versus tumour environments. They reveal that the previously uncharacterized transcription factor FLYWCH1 directly interacts with the Wnt/GSK-3ß axis, impacting critical signalling pathways that control intestinal regeneration and influencing colorectal cancer (CRC) development.
Date:
26 November 2024
Kim Hardie awarded Freedom of the City of London

Kim Hardie awarded Freedom of the City of London

Description
The award of the 'Freedom of the City of London' is an ancient tradition and unique part of London's history. Today, the Lord Mayors who award it use it to promote networking, economy boosting and charitable activities alongside recognizing achievements across a broad sphere. The previous recipients include Lord Nelson, Queen Elizabeth II and Florence Nightengale as well as notable scientists including Sir Paul Nurse more recently. BDI's Kim Hardie received a nomination in March 2024 from the Rt Hon the Lord Mayor, Professor Michael Mainelli and Alderman Alastair King, in recognition of her services to Microbiology including governance of related Professional Societies.
Date:
26 November 2024
The GlycoCell UKRI Engineering Biology Mission Hub awarded a £300k 'Seed Corn' grant by UKRI

The GlycoCell UKRI Engineering Biology Mission Hub awarded a £300k 'Seed Corn' grant by UKRI

Description
GlycoCell works on transforming biomanufacturing for health by safe microbial biomanufacturing of glycans and glycoproteins for vaccines, therapeutics, diagnostics and new drug targets. Led from Nottingham by PI John Heap, Ben Blount and Alex Faulds-Pain, in collaboration with other UK universities and industrial partners, the Seed Corn fund will drive the commercialisation of engineering biology discoveries and the creation of new engineering biology ventures.
Date:
26 November 2024

 

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