- Description
- A new study by BDI Researchers from the UoN Faculty of Science explores a popular anti-aging peptide, its ability to strengthen the skin barrier, and establishes a methodological benchmark for measuring the effects of cosmetic peptides on skin mechanics.
- Date:
- 07 March 2025
- Description
- BDI post-doc researchers have found a way to enhance butyrate production, a key compound linked to gut health.Using a novel rapid genome-proteome approach, they identified enzymes that limit butyrate production and successfully increased output by over-expressing key genes. This breakthrough could lead to stronger probiotics with greater health benefits.
- Date:
- 07 March 2025
- Description
- A recent study by BDI's School of Medicine collegues uncovers a novel regulatory mechanism of ß-catenin—a key player in Wnt signalling—distinguishing its role in healthy tissue versus tumour environments. They reveal that the previously uncharacterized transcription factor FLYWCH1 directly interacts with the Wnt/GSK-3ß axis, impacting critical signalling pathways that control intestinal regeneration and influencing colorectal cancer (CRC) development.
- Date:
- 26 November 2024
- Description
- The award of the 'Freedom of the City of London' is an ancient tradition and unique part of London's history. Today, the Lord Mayors who award it use it to promote networking, economy boosting and charitable activities alongside recognizing achievements across a broad sphere. The previous recipients include Lord Nelson, Queen Elizabeth II and Florence Nightengale as well as notable scientists including Sir Paul Nurse more recently. BDI's Kim Hardie received a nomination in March 2024 from the Rt Hon the Lord Mayor, Professor Michael Mainelli and Alderman Alastair King, in recognition of her services to Microbiology including governance of related Professional Societies.
- Date:
- 26 November 2024
- Description
- GlycoCell works on transforming biomanufacturing for health by safe microbial biomanufacturing of glycans and glycoproteins for vaccines, therapeutics, diagnostics and new drug targets. Led from Nottingham by PI John Heap, Ben Blount and Alex Faulds-Pain, in collaboration with other UK universities and industrial partners, the Seed Corn fund will drive the commercialisation of engineering biology discoveries and the creation of new engineering biology ventures.
- Date:
- 26 November 2024
- Description
- A new study from Prof Alvaro Mata's group has successful turned blood into personalised and tunable regenerative implant.
- Date:
- 26 November 2024
- Description
- New national hub (HALo) underpinned by a 6-year programme award funded by EPSRC. HALo will establish a multi-disease cross-technology UK national programme for long-acting therapeutics (LATs), to overcome unmet clinical needs not addressable using conventional medicines.
- Date:
- 26 November 2024
- Description
- Read the latest article from Mata Lab on a gentle dis-assemble protocol to retrieve living cells from peptide hydrogels
- Date:
- 26 November 2024
- Description
- Read a latest review from Mata Lab and colleagues on Biofabrication and biomanufacturing in Ireland and the UK
- Date:
- 26 November 2024
- Description
- The GlycoWeb programme led by BDI's Cathy Merry, Professor of Stem Cell Glycobiology, will look at the link between the structure and function of cell-surface sugar biomolecules called Glycosaminoglycans (GAGs). GAGs have been shown to play critical roles in a multitude of biological processes, including cell signalling and development and host-pathogen interactions. The team assembled for this programme will apply a diverse set of approaches to address fundamental knowledge gaps surroudning GAGs using an ambitious multidisciplinary approach, integrating analyses at the transcriptional through to the multicellular level.
- Date:
- 14 November 2023