Research

Our researchers

Research themes BDI Early Careers researchers

Search the table below to find out more about our researchers. You are able to filter the table by searching for names, research themes, keywords, and techniques.

 
Full list of our researchers
NameResearch themeKeywordsTechniques

Cinzia Allegrucci

  • Defeating Cancer
  • Regenerating and Modelling Tissues
  • Pioneering Therapeutics
  • Cancer
  • Stem cells
  • Epigenetics
  • Disease modelling
  • Genetics
  • iPSC technology
  • 3D cell culture model
  • In Vitro assays
  • Epigenetic analyses

Kenton Arkill

  • Defeating cancer
  • Demystifying Biomolecular complexity
  • Regenerating and Modelling Tissues
  • Vascular permeability
  • Endothelial glycocalyx
  • Electron
  • Microscopy
  • Correlative microscopy techniques
  • Functional permeability assays
  • 3D TEM
  • Correlative microscopy techniques

Jennifer Ashworth

  • Regenerating and Modelling Tissues
  • Defeating Cancer
  • Demystifying Biomolecular Complexity
  • Biomaterials
  • Fibrosis
  • Cancer research
  • 3D in vitro models
  • Imaging tissue
  • 3D cell culture
  • Biomaterials design & fabrication
  • Primary cell/organoid culture
  • Confocal imaging
  • Micro-CT analysis

Steve Atkinson

  • Taming Microbes
  • Demystifying Biomolecular Complexity
  • Pioneering therapeutics
  • Yersinia pestis
  • Plague
  • Black death
  • Molecular genetic pathways
  • Antibiotic resistance
  • Plague insect infection
  • Soil infection
  • Molecular genetics of plague

Dave Bates

  • Defeating Cancer
  • Regenerating and Modelling tissues
  • Demystifying Biomolecular Complexity
  • Angiogenesis
  • Vascular remodelling
  • Cholangiocarcinoma
  • Renal glomerular physiology
  • Diabetes
  • In vivo imaging
  • RNA splicing
  • Molecular and cellular biology
  • Drug discovery

Andrew Benest

  • Defeating cancer
  • Regenerating and Modelling Tissues
  • Demystifying Biomolecular Complexity
  • Endothelial cells
  • Lymphatics
  • Angiogenesis
  • Vasculature
  • Transcription factors
  • Transcriptomics
  • In Vivo modelling
  • Confocal microscopy

Ben Blount

  • Engineering Biology
  • Synthetic genomics
  • Synthetic biology
  • Microbial strain engineering
  • Genome engineering
  • Yeast genetics
  • DNA assembly
  • CRISPR
  • Chromosome design
  • SCRaMbLE

Daniel Booth

  • Defeating Cancer
  • Engineering Biology
  • Chromosomes
  • Mitosis
  • Advanced-imaging
  • Cancer
  • Cell-division

 

  • CLEM
  • Electron microscopy
  • Advanced proteomics
  • Advanced imaging
  • Light-microscopy
  • Volume microscopy

Tracey D Bradshaw

  • Defeating Cancer
  • Pioneering Therapeutics
  • Demystifying Biomolecular Complexity
  • Cancer
  • Pharmacology
  • Drug-discovery
  • Apoferritin
  • Molecular mechanisms
  • Tissue culture
  • Cell biology
  • MTT
  • Western blot
  • Flow cytometry

Lee Buttery

  • Regenerating and Modelling Tissues
  • Engineering Biology
  • Demystifying Biomolecular Complexity
  • 3D cell models
  • Stem cells
  • Osteoblasts
  • Cell-materials interactions
  • Tissue engineering
  • 3D and ES cell culture
  • Osteoblast culture
  • Immunocytochemistry
  • Optical tweezers for cell biology

Miguel Camara

  • Taming microbes
  • Demystifying Biomolecular Complexity

  • Biofilms
  • Quorum sensing
  • Antimicrobials
  • Microbial gene regulation
  • Antimicrobial target discovery
  • Biofilm model design
  • Biofilm imaging
  • Bacterial transcriptomics
  • Bioreporter design,
  • HTP antimicrobial testing

Weng Chan

  • Pioneering Therapuetics
  • Taming Microbes
  • Demystifying Biomolecular Complexity
  • Antibiotic discovery
  • Medicinal chemistry
  • Chemical biology
  • Antivirulence
  • Peptide chemistry
  • Solid-phase peptide synthesis
  • Organic synthesis
  • In vitro antimicrobial assay
  • Drug design

Yan Chen

  • Defeating Cancer

 

  • Artificial Intelligence
  • Quality assurance
  • Digital screening
  • Medical imaging
  • Programming
  • Algorithms
  • Artificial intelligence
  • DICOM images processing

Rachel Clifford

  • Demystifying Biomolecular Complexity
  • Pioneering Therapeutics
  • Respiratory
  • Epigenetics
  • Transcriptional regulation
  • DNA methylation
  • Inhaled exposures
  • Primary cell culture
  • Methylomics
  • Histone modification analysis
  • Transcriptomics
  • Molecular biology

Beth Coyle

  • Defeating Cancer
  • Regenerating and Modelling Tissues
  • Pioneering Therapeutics
  • Paediatric brain tumours
  • Resistance
  • Metastasis
  • Tumour microenvironment
  • 3D cell cuture
  • Apoptosis
  • Cytotoxicity
  • Migration assays

Madhumita Dandapani

  • Defeating Cancer
  • Pioneering Therapeutics
  • Childhood cancer
  • Brain tumours
  • Cancer metabolism
  • Clinical trials
  • Global health

  • Immunohistochemistry
  • Western blotting
  • Cell culture
  • Multi-omics
  • Systematic reviews

Lodewijk V. Dekker

  • Pioneering Therapeutics
  • Defeating Cancer
  • Demystifying Biomolecular Complexity
  • Drug discovery
  • Cancer
  • Thrombosis
  • Protein kinase
  • Protein interactions
  • Biochemical assays
  • Cellular assays
  • Enzyme assays
  • Assay development
  • High throughput screening

Chris Denning

  • Regenerating and Modelling Tissues
  • Demystifying Biomolecular Complexity
  • Pioneering Therapeutics
  • Human pluripotent stem cells (hPSCs)
  • Heart/cardiovascular disease
  • Drug discovery and evaluation
  • Regenerative medicine
  • Cardiovascular lineage differentiation
  • CRISPR engineering
  • Phenotype-genotype correlations
  • Automation

James Dixon

  • Pioneering Therapeutics
  • Regenerating and Modelling Tissues
  • Defeating Cancer
  • Gene therapy
  • Gene editing 
  • Vaccines
  • Nucleic acid delivery
  • Regenerative medicine
  • Genetic engineering/editing
  • Nanoformulation
  • Reporter assays
  • Particle characterisation
  • Biomaterials
Ingrid Dreveny
  • Demystifying Biomolecular Complexity
  • Defeating Cancer
  • Engineering Biology
  • Proteases in the ubiquitin system
  • Protein structure
  • Structure-aided drug design
  • Enzyme specificity
  • Proteins in biotechnology
  • Macromolecular X-ray crystallography
  • Isothermal titration calorimetry
  • Biochemistry
  • Protein engineering

Lindy Durrant

  • Defeating Cancer
  • Pioneering Therapeutics
  • Demystifying Biomolecular Complexity
  • Cancer immunotherapy
  • Vaccines
  • Monoclonal antibodies
  • T cells,
  • Post translational modifications
  • Production of antibodies
  • Vaccine design
  • Cancer animal models
  • T cell assays
  • ELISAs

Isioma Egbuniwe

  • Defeating Cancer
  • Demystifying Molecuar Complexity
  • Pioneering Therapeutics
  • Bile duct cancer
  • Tumour microenvironment
  • T and B cells
  • Lymphatics
  • Digital pathology
  • Primary cell isolation and culture
  • Multi-parameter flow cytometry
  • 3D tumour-immune cell co-culture systems
  • Histopathology
  • Image analysis

Libby Ellis

  • Defeating Cancer
  • Cancer epidemiology
  • Population health
  • Inequalities
  • Cancer outcomes
  • Health policy
  • Epidemiological and statistical methodolog
  • Electronic health data analysis

Jonas Emsley

  • Demystifying Biomolecular Complexity
  • Taming Microbes
  • Pioneering Therapeutics
  • Structural biology
  • Protein crystallography
  • Protease structure
  • Receptor structure
  • Drug development
  • Protein crystallography
  • Isothermal titration calorimetry
  • Surface plasmon resonance
  • Molecular docking
Mattea Finelli
  • Demystifying Biomolecular Complexity
  • Regenerating and Modelling Tissues
  • Pioneering Therapeutics
  • Neurodegenerative diseases
  • Redox mechanisms
  • Oxidative and nitrosative stresses
  • Proteomics
  • Post-translational modifications of proteins
  • Quantitative/redox/PTMs proteomics
  • Cell- and recombinant protein-based assays
  • Stem cell derived disease models
  • Various cell cultures (cortical, cerebellar, hippocampal, DRG, motor neurons)

Hester Franks

  • Defeating Cancer
  • Demystifying Biomolecular Complexity
  • Cancer
  • Immunotherapy
  • Macrophages
  • Tumour microenvironment
  • Melanoma
  • Primary immune cell isolation and culture
  • Flow cytometry
  • RNAScope

Kevin Gaston

  • Defeating Cancer
  • Demystifying Biomolecular Complexity
  • Cancer
  • Gene regulation
  • Transcription
  • Cell biology
  • Protein-DNA interactions
  • RNA sequencing
  • ChIP sequencing
  • Cell migration assays
  • Cell viability assays
  • EMSA

Pavel Gershkovich

  • Pioneering Therapeutics
  • Defeating Cancer
  • Biopharmaceutics
  • Pharmacokinetics
  • Drug delivery
  • Intestinal lymphatic transport
  • Targeted biodistribution

 

  • Bioanalysis
  • HPLC
  • In Vivo pharmacokinetics
  • In vivo biodistribution
  • Pharmacokinetic modelling and simulation

Amanda Goodwin

  • Regenerating and Modelling Tissues
  • Demystifying Biomolecular Complexity
  • Fibrosis
  • Development
  • Lung repair
  • In vitro cell stretch (Flexcell)
  • G protein knockdown studies
  • TMLC assays (TGFbeta signalling assay)
  • ECM crossover studies

Anna Grabowska

  • Defeating Cancer
  • Demystifying Biomolecular Complexity
  • Pioneering therapeutics
  • Cancer models
  • Tumour microenvironment
  • Target validation
  • Drug screening
  • Drug delivery
  • Cancer modelling
  • 3D tissue culture
  • Quantitative PCR
  • Immunohistochemistry

Andrew Green

  • Defeating Cancer
  • Demystifying Biomolecular Complexity
  • Breast cancer
  • Molecular pathology
  • Glutamine metabolism
  • Genotype
  • Phenotype
  • Immunohistochemistry
  • Tissue microarrays (TMAs)
  • Laser microdissection
  • Gene expression profiling
  • In situ hybridisation

Ruth Griffin

  • Pioneering Therapeutics
  • Taming Microbes
  • Engineering Biology
  • Oral vaccine delivery systems
  • Infectious diseases
  • Gene cloning and protein purification
  • Formulation
  • In vivo immunogenicity and challenge studies
  • Antibody assays

Richard Grundy

  • Defeating Cancer
  • Demystifying Biomolecular Complexity
  • Pioneering Therapeutics
  • Childhood Brain Tumours
  • Ependymoma
  • Biomarkers
  • Immunobiology
  • Methylation profiling
  • Molecular stratification
 

Nicholas Hannan

  • Regenerating and Modelling Tissues
  • Pioneering Therapeutics
  • Demystifying Biomolecular Complexity
  • Stem cells
  • Disease modelling
  • Respiratory disease
  • Liver disease
  • Inflammatory bowel disease
  • Stem cell differentiation
  • Cell phenotyping
  • Gene editing and CRISPR base editing
  • Organoids

Kim Hardie

  • Taming Microbes
  • Biofilms
  • Antimicrobial resistance
  • Bacteria
  • Pathogenicity
  • Protein secretion
  • Fluorescent microscopy
  • Infection models
  • Microbiology
  • Protein biochemistry
  • Metabolite detection
John Heap
  • Engineering Biology
  • Taming Microbes
  • Pioneering Therapeutics
  • Engineering biology/Synthetic biology
  • Metabolic engineering
  • Biotechnology
  • Biocatalysis
  • Enzyme evolution
  • Engineering biology/Synthetic biology
  • Metabolic engineering
  • Biotechnology
  • Biocatalysis
  • Enzyme evolution
Stephan Heeb
  • Taming Microbes
  • Engineering Biology
  • Demystifying Biomolecular Complexity
  • Bacterial infections
  • Virulence
  • Quorum sensing
  • Gene expression
  • Antimicrobial strategies
  • Bacterial genomics
  • RNA-Seq
  • RNA protein interactions
  • Construction of bacterial vectors

Mohammad Ilyas

  • Defeating Cancer
  • Regenerating
  • Modelling Tissues
  • Regenerating and Modelling Tissues
  • Colorectal cancer
  • Mutation analysis
  • Liquid biopsy
  • Cancer biomarkers
  • Tissue modelling
  • Histopathology
  • PCR
  • Co-culture models
  • Gene cloning

Andrew Jackson

  • Defeating Cancer
  • Demystifying Biomolecular Complexity
  • Pioneering Therapeutics
  • Cancer
  • Immunotherapy
  • Dendritic Cells (DC)
  • T-cells
  • Signalling
  • Isolation of rare primary leukocyte subsets
  • Flow cytometry
  • Small molecule kinase inhibitors
  • Multi-cellular immune culture systems

Victoria James

  • Defeating Cancer
  • Pioneering Therapeutics
  • Regenerating and Modelling Tissues

  • Extracellular vesicles
  • RNA biology
  • Cancer metastasis
  • Epigenetics
  • Inter-cellular communication
  • Nanoparticle molecular biology
  • RNA biology
  • Cell biology
  • Epigenetics

Sheela Jayaraman

  • Defeating Cancer
  • Demystifying Biomolecular Complexity
  • Pioneering Therapeutics

 

  • Gene expression
  • Chromatin
  • PRH/HHEX
  • Cell signalling
  • Transcriptomics
  • RNAseq
  • Western blotting
  • Subcloning
  • Chromatin immunoprecipitation

Jennie Jeyapalan

  • Defeating Cancer
  • Demystifying Biomolecular Complexity
  • Pioneering Therapeutics
  • Epigenomics
  • Prostate cancer
  • Transcriptional regulation
  • Splicing
  • Genomics
  • RNA seq analysis
  • Molecular biology
  • Cell culture

Simon Johnson


  • Pioneering Therapeutics
  • Regenerating and Modelling Tissues
  • Tissue remodelling
  • Proteases Extracellular matrix
  • Rare lung disease
  • Drug repurposing
  • Protease assays
  • Complex cell culture
  • Molecular pathology

Anna Malecka

  • Defeating Cancer
  • Demystifying Biomolecular Complexity
  • Cancer
  • Immunology
  • Macrophages
  • Comparative oncology
  • Immune-stromal interactions
  • Flow cytometry
  • Stroma-Immune co-culture system
  • Cell culture

Barrie Kellam

  • Pioneering Theraputics
  • Demystifying Biomolecular Therapeutics
  • Regenerating and Modelling Tissues
  • Medicinal chemistry
  • Fluorescent ligands
  • G protein-coupled receptors
  • Drug discovery
  • Medicinal chemistry
  • Molecular modelling
  • Biospectroscopy
  • HPLC
  • Fluorescence Imaging

Laura Kilpatrick

  • Demystifying Biomolecular Complexity
  • Defeating Cancer
  • Molecular pharmacology
  • G protein coupled receptors
  • Receptor tyrosine kinases
  • Signalling complexes
  • Protein-protein interactions
  • Bioluminescence resonance energy transfer (BRET)
  • Fluorescence correlation spectroscopy
  • Fluorescence imaging
  • Pharmacological assays
Katalin Kovacs
  • Engineering Biology
  • Taming Microbes
  • Engineering biology
  • Metabolic engineering
  • Autotrophic microorganisms
  • Bioelectochemical synthesis
  • Circular economy
  • Molecular biology
  • Microscopy
  • Microbial cultivation
  • Electrofermentation
  • Plastid engineering
Charlie Laughton
  • Pioneering Therapeutics
  • Demystifying Biomolecular Complexity
  • Biomolecular structure
  • Molecular recognition
  • Drug design
  • Formulation design
  • Molecular dynamics
  • Molecular dynamics simulations
  • Protein structure prediction
  • Virtual screening
  • Machine learning
  • Software development

Anbarasu Lourdusamy

  • Defeating Cancer
  • Pioneering Therapeutics
  • Brain cancer
  • Childhood cancer
  • Systems biology
  • Artificial intelligence
  • Big data
  • Bioinformatics
  • NGS (RNAseq, ChIPseq, scRNAseq and ATAC-seq) data analysis
  • Machine learning
  • Statistics
  • High-performance computing

Srinvasan Madhusudan

  • Defeating Cancer
  • Pioneering Therapeutics
  • Demystifying Biomolecular Complexity
  • Medical oncology
  • Clinical trials
  • Breast cancer
  • DNA repair therapeutics
  • Drug discovery
  • DNA repair assays
  • Immunohistochemical techniques
  • Clinical trial methodologies

Stewart Martin

  • Defeating Cancer
  • Pioneering Therapeutics
  • Demystifying Biomolecular Complexity
  • Breast, brain and ovarian cancer
  • Radiotherapy
  • Metastasis
  • Novel drugs
  • Redox homeostasis
  • Calpain proteases
  • Radiation biology
  • Immunohistochemistry
  • Cell and molecular Biology

Alvaro Mata

  • Regenerating and Modelling Tissues
  • Engineering Biology
  • Pioneering Therapeutics
  • Biomaterials
  • Tissue engineering
  • Regenerative materials
  • In vitro models
  • Biomineralization
  • Self-assembly
  • Bioprinting
  • Electron microscopy

Alan McIntyre

  • Defeating Cancer
  • Pioneering Therapeutics
  • Demystifying Biomolecular Complexity
  • Cancer
  • Hypoxia (low oxygen)
  • Acidosis
  • Transcription
  • Epigenetics
  • Angiogenesis
  • CRISPR CAS9
  • RNA-SEQ
  • ChIP
  • Tumour cell phenotype assays
  • Hypoxia and acidosis investigations

Cathy Merry

  • Demystifying Biomolecular Complexity
  • Regenerating and Modelling Tissues
  • Defeating Cancer
  • Matrix biology
  • Cancer research
  • Disease modelling
  • Glycobiology
  • Glycobiology
  • Hydrogel development
  • Stem cell culture and differentiation
  • Matrix biology
  • In vitro disease models

Nigel Minton

  • Engineering Biology
  • Taming Microbes
  • Defeating Cancer
  • Exploiting autotrophy
  • Reducing carbon emissions
  • Industrial biotechnology
  • Microbial pathogenesis
  • Anaerobes
  • Synthetic biology
  • Metabolic engineering
  • Gas fermentation
  • Genome editing
  • Therapeutic delivery systems
Shailesh N. Mistry
  • Pioneering Therapeutics
  • Demystifying Biomolecular Complexity
  • Defeating Cancer
  • Drug discovery
  • Chemical biology
  • Medicinal chemistry
  • G protein-coupled receptors (GPCRs)
  • Allosteric modulators
  • Medicinal chemistry
  • Compound purification
  • Spectroscopic analysis
  • Ligand/structure-based drug discovery

Nigel Mongan

  • Defeating Cancer
  • Bioinformatics
  • Precision medicine
  • Prostate cancer
  • Breast cancer
  • Bioinformatics
  • Epitranscriptomics

Abhik Mukarjee

  • Defeating Cancer
  • Demystifying Biomolecular Complexity
  • Regenerating and Modelling Tissues
  • Digital/molecular pathology
  • Gastrointestinal and pancreaticobiliary cancers
  • Translational therapeutics
  • Inflammatory bowel disease
  • Histopathology and immunohistochemistry
  • Digital pathology and image analyses
  • Molecular pathology
  • Functional biology

Paloma Ordóñez Morán

  • Defeating Cancer
  • Regenerating and Modelling Tissues
  • Engineering Biology
  • Stem cells
  • Inflammation
  • Differentiation
  • Cancer
  • Tumour heterogeneity
  • 3D organoids
  • Primary mouse and human cell culture
  • Stem cell-based approaches
  • In vivo assays
  • Gene expression

Ellis O'Neil

  • Taming Microbes
  • Engineering Biology
  • Demystifying Biomolecular Complexity
  • Natural products
  • Algal biotechnology
  • Biotransformation
  • Analytical chemistry
  • Mass spectrometry
  • Protein expression and purification
  • Genome mining

Poulam Patel

  • Defeating Cancer
  • Pioneering Therapeutics
  • Melanoma
  • Renal cancer
  • Cancer immunotherapy
  • Clinical trials
  • Translational medicine
  • Clinical trials
  • Immune assays

Ruman Rahman

  • Defeating Cancer
  • Pioneering Therapeutics
  • Brain cancer
  • Cancer heterogeneity
  • Cancer metabolism
  • Biomaterial-based drug delivery
  • Integrated genomics
  • 3D primary tumour culture
  • qRT-PCR
  • Gene microarrays/knockdowns
  • Western blotting

Emad Rakha

  • Defeating Cancer
  • Demystifying Biomolecular Complexity
  • Engineering Biology
  • Breast cancer
  • Pathology
  • Classification
  • Prognosis
  • Digital pathology
  • AI
  • Predictive and prognostic markers
  • Digital pathology
  • Immunohistochemistry
  • Image analysis

Judith Ramage

  • Defeating Cancer
  • Pioneering Therapeutics
  • Cancer
  • Immunology
  • T-lymphocytes
  • Vaccines
  • Multiplex fluorescence immunohistochemistry
  • T-cell assays

Frankie Rawson

  • Regenerating and Modelling Tissues
  • Defeating Cancer
  • Pioneering Therapeutics

 

  • Wireless bioelectronics
  • Bioelectricity
  • Electrochemistry
  • Bionanotechnology
  • Bioelectronic medicine
  • SECM-AFM
  • Voltammtery
  • Amperomerty
Tim Ritzmann
  • Defeating Cancer
  • Demystifying Biomolecular Complexity
  • Pioneering Therapeutics
  • Childhood brain tumours
  • Brain tumour immunity
  • Childhood cancer
  • Ependymoma
  • Cancer recurrence
  • RNA-sequencing
  • Multiplex immunofluorescence
  • Immunohistochemistry
  • Clinical data analysis
  • Childhood brain tumour clinical trials
Karen Robinson
  • Taming Microbes
  • Defeating Cancer
  • Pioneering Therapeutics
  • Helicobacter pylori
  • Antimicrobial resistance
  • Infection and immunity
  • Gastric cancer
  • Bacterial virulence
  • Flow cytometry
  • Real-time PCR
  • Immunohistochemistry
  • Antimicrobial sensitivity testing
  • Immune cell purification and culture
Felicity Rose
  • Regenerating and Modelling Tissues
  • Pioneering Therapeutics
  • Taming Microbes
  • Biointerfaces
  • Biomaterials
  • Peptide materials
  • Hydrogels
  • Computational material science
  • Surface modification & analysis
  • Polymerisation kinetics
  • Light & enzyme responsive materials
  • Material characterisation
Ian Sayers
  • Pioneering Therapeutics
  • Demystifying Biomolecular Complexity
  • Regenerating and Modelling Tissues

  • Molecular
  • Genetic and cellular mechanisms underlying asthma and chronic obstructive pulmonary disease
  • Virus-host interactions
  • Stratified medicine
  • Gene discovery
  • Primary airway cell and tissue models
  • Functional genetics
  • Transcriptomics
  • Patient translational studies

Claire Seedhouse

  • Defeating Cancer
  • Pioneering Therapeutics
  • Demystifying Biomolecular Therapeutics
  • Blood cancers
  • Drug resistance
  • Stem cells
  • Dormancy
  • Mutations
  • Quantitative PCR
  • Flow cytometry
  • Primary suspension cultures

Abdol Shams-Nateri

  • Defeating Cancer
  • Regenerating and Modelling Tissues
  • Pioneering Therapeutics
  • Adult stem cells and cancer
  • Precision oncology/personalized cancer treatments
  • Intra-tumour heterogeneity
  • Cell signalling and transcription
  • Ubiquitin proteasome system and F-box proteins
  • 3D Organoids and explants models
  • Gene targeting & transgenics
  • CRISPR-Cas gene editing systems
  • Epithelial and hematopoietic stem cells assays

Stuart Smith

  • Defeating Cancer
  • Pioneering Therapeutics
  • High grade glioma
  • Low grade glioma
  • Childhood brain tumours
  • Drug delivery
  • Tumour heterogeneity
  • rtPCR
  • RNA methylation
  • IHC
  • FACS
Philippe Soucaille
  • Engineering Biology
  • Demystifying Biomolecular Complexity
  • Metabolic engineering
  • System biology
  • Synthetic biology
  • Microbial physiology - CO2 fixation
  • Enzyme evolution
  • Bacterial genome editing
  • Fluxomics
  • Proteomics
  • Transcriptomics
Panos Soultanas
  • Demystifying Biomolecular Complexity
  • Taming Microbes
  • Defeating Cancer
  • DNA replication
  • DNA repair
  • Replication-metabolism regulation
  • Genome stability
  • Protein expression
  • Purification
  • Polymerase and helicase assays
  • Analytical ultracentrifugation
  • SPR

Ian Spendlove


  • Pioneering Therapeutics
  • Defeating Cancer
  • Demystifying Biomolecular Complexity
  • Controlling iTreg
  • Engineering T cells
  • Cloning TCRs from cancer patients
  • Cancer survivors
  • Anti cancer antibodies
  • TCR cloning/transduction
  • CRISPR-Cas9 of primary leukocytes
  • Flow sorting rare T cells
  • Differentiating iTreg
  • Autophagosome purification

Michael Stocks

  • Pioneering Therapeutics
  • Demystifying Biomolecular Complexity
  • Defeating Cancer
  • Medicinal chemistry
  • Drug discovery
  • Cancer
  • Antimicrobial resistance
  • Prodrugs
  • Synthesis
  • Drug optimisation
  • Drug delivery
  • Medicinal chemistry

Sarah Storr

  • Defeating Cancer
  • Demystifying Biomolecular Complexity
  • Pioneering Therapeutics
  • Cancer
  • Breast cancer
  • DARPP-32
  • Calpain
  • Cell signalling
  • Cell culture
  • Bioinformatics
  • Immunohistochemistry
  • Molecular biology
  • Protein purification

Amanda Tatler

  • Pioneering Therapeutics
  • Regenerating and Modelling Tissues
  • Respiratory disease
  • Tissue remodelling
  • Fibrosis
  • Matrix
  • 3D models
  • Precision cut tissue slices
  • In vivo respiratory models
  • Molecular biology
  • TGFb activation assays
  • Immunohistochemistry/ immunofluorescence

Neil Thomas

  • Pioneering Therapeutics
  • Defeating Cancer
  • Engineering Biology
  • Enzyme mechanism
  • Enzyme inhibitors
  • Biopharmaceutics
  • Silk and other protein-based biomaterials
  • Nanobiotechnology
  • Bioconjugation
  • Chemiluminescence
  • Un-natural amino acid mutagenesis
  • Enzyme activity assays
  • Enzyme inhibitor design

Alex Thompson

  • Defeating Cancer
  • Regenerating and Modelling Tissues
  • Pioneering Therapeutics
  • Blood cancer
  • Stem cell technologies
  • Pre-clinical evaluation
  • Next-generation models
  • Drug discovery
  • In vivo modelling
  • iPSC maintenance and differentiation
  • Haematopoiesis
  • Colony-forming assays
  • Gene expression profiling

Lisa White

  • Regenerating and Modelling Tissues
  • Pioneering Therapeutics
  • Regenerative medicine
  • Biomaterials
  • Extracellular matrix
  • Hydrogels
  • Microparticles
  • Decellularization
  • Micro x-ray computed tomography
  • Mammalian cell culture
  • Biomaterials characterisation
  • Supercritical CO2

Huw Williams

  • Demystifying Biomolecular Complexity
  • Pioneering Therapeutics
  • Engineering Biology
  • NMR
  • Molecular interactions
  • Molecular structure
  • Analytical
  • Kinetics
  • NMR
  • Molecular interactions
  • Solid state NMR
  • Molecular dynamics
  • Molecular structure
Paul Williams
  • Taming Microbes
  • Pioneering Therapeutics
  • Demystifying Molecuar Complexity
  • Quorum sensing
  • Biofilms
  • Bacteria
  • Biomaterials
  • Antimicrobial agents
  • Bacterial genetics
  • Bacterial culture
  • Antimicrobial assays
  • Quorum sensing assays
  • Microscopy/imaging
Klaus Winzer
  • Engineering Biology
  • Taming Microbes
  • Microbial metabolism
  • Biological engineering
  • Synthetic biology
  • Bacterial carbon capture
  • Quorum sensing
  • Anaerobic microbiology
  • Gas fermentation
  • Genetic modification of bacteria
  • Adaptive laboratory evolution

Jing Yang

  • Regenerating and Modelling Tissues
  • Defeating Cancer
  • Engineering Biology
  • Biomaterials
  • 3D Bioprinting
  • Tissue engineering
  • Regenerative medicine
  • Immunomodulatory materials
  • 3D printing
  • Biomaterial preparation
  • Chemical characterisation
  • Mechanical testing
  • Cell culture
Mischa Zelzer
  • Regenerating and Modelling Tissues
  • Demystifying Molecuar Complexity
  • Engineering Biology
  • Biointerfaces
  • Biomaterials
  • Peptide materials
  • Hydrogels
  • Computational material science
  • Surface modification and analysis
  • Polymerisation kinetics light and enzyme responsive materials
  • Material characterisation
Ying Zhang
  • Engineering biology
  • Taming microbes
  • Industrial biotechnology
  • Biological engineering
  • Single-carbon utilising bacteria for carbon capture
  • Sustainable bioproducts
  • Biorecovery
  • Synthetic biology
  • Bacterial genome editing
  • Metabolic engineering
  • Protein engineering
  • Strain improvement

World-class research at the University of Nottingham

University Park
Nottingham
NG7 2RD
+44 (0) 115 951 5151
research@nottingham.ac.uk
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