Contact

• workRoom W/B 1439
  Queen's Medical Centre
  Nottingham
  NG7 2UH
  UK
• work0115 823 1177
• Robin.Damion@nottingham.ac.uk

Research Summary

Deuterium magnetic resonance imaging (MRI) and spectroscopy (MRS), in vivo, using various deuterium-labeled substrates:

• Deuterium oxide (D₂O, heavy water) can potentially be used to measure lipid turnover via deuterium incorporation into triglycerides, and muscle-fibre organisation via the magnitude and angular-dependence or the quadrupolar splitting of the water spectrum.
• Glucose ([6,6'-D₂]glucose or [1,2,3,4,5,6,6'-D₇]glucose) can be used to measure glucose uptake and metabolism (via detection of lactate and glutamine/glutamate) in tissues for physiological studies or detection of tumours.

Selected Publications

• COCKING, DANIEL, DAMION, ROBIN, FRANKS, HESTER, JACONELLI, MATTHEW, WILKINSON, DANIEL, BROOK, MATTHEW, AUER, DOROTHEE and BOWTELL, RICHARD, 2023. Deuterium imaging at 7T during D2O dosing Magnetic Resonance in Medicine. 89(4), 1514-1521
• MCGARRY, BRYONY L., DAMION, ROBIN A., CHEW, ISABEL, KNIGHT, MICHAEL J., HARSTON, GEORGE W. J., CARONE, DAVIDE, JEZZARD, PETER, SITARAM, AMITH, MUIR, KEITH W., CLATWORTHY, PHILIP and KAUPPINEN, RISTO A., 2020. A Comparison of T-2 Relaxation-Based MRI Stroke Timing Methods in Hyperacute Ischemic Stroke Patients: A Pilot Study JOURNAL OF CENTRAL NERVOUS SYSTEM DISEASE. 12,
• DAMION, ROBIN A., KNIGHT, MICHAEL J., MCGARRY, BRYONY L., BOSNELL, ROSE, JEZZARD, PETER, HARSTON, GEORGE W. J., CARONE, DAVIDE, KENNEDY, JAMES, EL-TAWIL, SALWA, ELLIOT, JENNIFER, MUIR, KEITH W., CLATWORTHY, PHILIP and KAUPPINEN, RISTO A., 2019. Quantifying T-2 relaxation time changes within lesions defined by apparent diffusion coefficient in grey and white matter in acute stroke patients PHYSICS IN MEDICINE AND BIOLOGY. 64(9),
• KNIGHT, MICHAEL J., DAMION, ROBIN A., MCGARRY, BRYONY L., BOSNELL, ROSE, JOKIVARSI, KIMMO T., GROHN, OLLI H. J., JEZZARD, PETER, HARSTON, GEORGE W. J., CARONE, DAVIDE, KENNEDY, JAMES, EL-TAWIL, SALWA, ELLIOT, JENNIFER, MUIR, KEITH W., CLATWORTHY, PHILIP and KAUPPINEN, RISTO A., 2019. Determining T2 relaxation time and stroke onset relationship in ischaemic stroke within apparent diffusion coefficient-defined lesions. A user-independent method for quantifying the impact of stroke in the human brain BIOMEDICAL SPECTROSCOPY AND IMAGING. 8(1-2), 11-28

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• COCKING, DANIEL, DAMION, ROBIN, FRANKS, HESTER, JACONELLI, MATTHEW, WILKINSON, DANIEL, BROOK, MATTHEW, AUER, DOROTHEE and BOWTELL, RICHARD, 2023. Deuterium imaging at 7T during D2O dosing Magnetic Resonance in Medicine. 89(4), 1514-1521
• MCGARRY, BRYONY L., DAMION, ROBIN A., CHEW, ISABEL, KNIGHT, MICHAEL J., HARSTON, GEORGE W. J., CARONE, DAVIDE, JEZZARD, PETER, SITARAM, AMITH, MUIR, KEITH W., CLATWORTHY, PHILIP and KAUPPINEN, RISTO A., 2020. A Comparison of T-2 Relaxation-Based MRI Stroke Timing Methods in Hyperacute Ischemic Stroke Patients: A Pilot Study JOURNAL OF CENTRAL NERVOUS SYSTEM DISEASE. 12,
• DAMION, ROBIN A., KNIGHT, MICHAEL J., MCGARRY, BRYONY L., BOSNELL, ROSE, JEZZARD, PETER, HARSTON, GEORGE W. J., CARONE, DAVIDE, KENNEDY, JAMES, EL-TAWIL, SALWA, ELLIOT, JENNIFER, MUIR, KEITH W., CLATWORTHY, PHILIP and KAUPPINEN, RISTO A., 2019. Quantifying T-2 relaxation time changes within lesions defined by apparent diffusion coefficient in grey and white matter in acute stroke patients PHYSICS IN MEDICINE AND BIOLOGY. 64(9),
• KNIGHT, MICHAEL J., DAMION, ROBIN A., MCGARRY, BRYONY L., BOSNELL, ROSE, JOKIVARSI, KIMMO T., GROHN, OLLI H. J., JEZZARD, PETER, HARSTON, GEORGE W. J., CARONE, DAVIDE, KENNEDY, JAMES, EL-TAWIL, SALWA, ELLIOT, JENNIFER, MUIR, KEITH W., CLATWORTHY, PHILIP and KAUPPINEN, RISTO A., 2019. Determining T2 relaxation time and stroke onset relationship in ischaemic stroke within apparent diffusion coefficient-defined lesions. A user-independent method for quantifying the impact of stroke in the human brain BIOMEDICAL SPECTROSCOPY AND IMAGING. 8(1-2), 11-28
• KNIGHT, MICHAEL J., DAMION, ROBIN A. and KAUPPINEN, RISTO A., 2018. Observation of angular dependence of T1 in the human white matter at 3T BIOMEDICAL SPECTROSCOPY AND IMAGING. 7(3-4), 125-133
• FOSTER, R. J., DAMION, R. A., RIES, M. E., SMYE, S. W., MCGONAGLE, D. G., BINKS, D. A. and RADJENOVIC, A., 2018. Imaging of nuclear magnetic resonance spin-lattice relaxation activation energy in cartilage ROYAL SOCIETY OPEN SCIENCE. 5(7),
• MENG, QINGEN, AN, SHUQIANG, DAMION, ROBIN A., JIN, ZHONGMIN, WILCOX, RUTH, FISHER, JOHN and JONES, ALISON, 2017. The effect of collagen fibril orientation on the biphasic mechanics of articular cartilage JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS. 65, 439-453
• FOSTER, RICHARD J., DAMION, ROBIN A., BABOOLAL, THOMAS G., SMYE, STEPHEN W. and RIES, MICHAEL E., 2016. A nuclear magnetic resonance study of water in aggrecan solutions ROYAL SOCIETY OPEN SCIENCE. 3(3),
• ROBIN A. DAMION, 2016. Grassmann variables and pseudoclassical Nuclear Magnetic Resonance Diffusion Fundamentals. 26(1), 1-23
• WIJAYATHUNGA, VITHANAGE N., RIDGWAY, JOHN P., INGHAM, EILEEN, TREANOR, DARREN, CAREY, DUANE, BULPITT, ANDY, MAGEE, DEREK, DAMION, ROBIN and WILCOX, RUTH K., 2015. A Nondestructive Method to Distinguish the Internal Constituent Architecture of the Intervertebral Discs Using 9.4 Tesla Magnetic Resonance Imaging SPINE. 40(24), E1315-E1322
• DAMION, ROBIN A., RADJENOVIC, ALEKSANDRA, INGHAM, EILEEN, JIN, ZHONGMIN and RIES, MICHAEL E., 2013. Orthogonal Invariant Sets of the Diffusion Tensor and the Development of a Curvilinear Set Suitable for Low-Anisotropy Tissues PLOS ONE. 8(11),
• HALL, CRAIG A., LE, KIM A., RUDAZ, CYRIELLE, RADHI, ASANAH, LOVELL, CHRISTOPHER S., DAMION, ROBIN A., BUDTOVA, TATIANA and RIES, MICHAEL E., 2012. Macroscopic and Microscopic Study of 1-Ethyl-3-methyl-imidazolium Acetate-Water Mixtures JOURNAL OF PHYSICAL CHEMISTRY B. 116(42), 12810-12818
• DAMION, R. A., PAWASKAR, S. S., RIES, M. E., INGHAM, E., WILLIAMS, S., JIN, Z. and RADJENOVIC, A., 2012. Spin-lattice relaxation rates and water content of freeze-dried articular cartilage OSTEOARTHRITIS AND CARTILAGE. 20(2), 184-190
• LOVELL, CHRISTOPHER S., WALKER, ADAM, DAMION, ROBIN A., RADHI, ASANAH, TANNER, STEVEN F., BUDTOVA, TATIANA and RIES, MICHAEL E., 2010. Influence of Cellulose on Ion Diffusivity in 1-Ethyl-3-Methyl-Imidazolium Acetate Cellulose Solutions BIOMACROMOLECULES. 11(11), 2927-2935
• BLUMICH, B, CALLAGHAN, PT, DAMION, RA, HAN, S, KHRAPITCHEV, AA, PACKER, KJ and STAPF, S, 2001. Two-dimensional NMR of velocity exchange: VEXSY and SERPENT JOURNAL OF MAGNETIC RESONANCE. 152(1), 162-167
• DAMION, RA, PACKER, KJ, SORBIE, KS and MCDOUGALL, SR, 2000. Pore-scale network modelling of flow propagators derived from pulsed magnetic field gradient spin echo NMR measurements in porous media CHEMICAL ENGINEERING SCIENCE. 55(24), 5981-5998
• STAPF, S, DAMION, RA and PACKER, KJ, 1999. Time correlations in fluid transport obtained by sequential rephasing gradient pulses JOURNAL OF MAGNETIC RESONANCE. 137(2), 316-323
• PACKER, KJ, STAPF, S, TESSIER, JJ and DAMION, RA, 1998. The characterisation of fluid transport in porous solids by means of pulsed magnetic field gradient NMR MAGNETIC RESONANCE IMAGING. 16(5-6), 463-469
• DAMION, RA and PACKER, KJ, 1997. Predictions for pulsed-field-gradient NMR experiments of diffusion in fractal spaces PROCEEDINGS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES. 453(1956), 205-211
• FOSTER, JE, DAMION, RA, VENNART, W, SUMMERS, IR, ELLIS, RE, BRASH, P and TOOKE, J, 1994. Magnetic resonance imaging of peripheral vascular disease and muscle atrophy in diabetes MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE. 2(3), 401-403
• DAMION, RA, VENNART, W, SUMMERS, IR and ELLIS, RE, 1994. WATER DIFFUSION-COEFFICIENT MEASUREMENTS IN THE FINGER BY MAGNETIC-RESONANCE-IMAGING MAGNETIC RESONANCE IMAGING. 12(6), 873-879