Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

Content: STOCKS, MJ, HAMZA, D, PAIRAUDEAU, G, STONEHOUSE, JP and THORNE, PV, 2007. Concise synthesis of novel 2,6-diazaspiro [3.3] heptan-1-ones and their conversion into 2,6-diazaspiro[3.3]heptanes Synlett. 2587-2589

Content: WARFIELD, RACHEL, BARDELANG, PHILIP, SAUNDERS, HELEN, CHAN, WENG C, PENFOLD, CHRISTOPHER, JAMES, RICHARD and THOMAS, NEIL R, 2006. Internally quenched peptides for the study of lysostaphin: an antimicrobial protease that kills Staphylococcus aureus. Organic and Biomolecular Chemistry. 4(19), 3626-38

Content: CHAN, W.C., HIGTON, A. and DAVIES, J.S., 2006. Amino acids. In: DAVIES, J.S., ed., Amino acids, Peptides and Proteins 35. Cambridge University Press, Cambridge, UK. 1-73

Content: PEREZ, T, ERCILLA, G, CHAN, W C and HARO, I, 2006. Antigenicity of chimeric and cyclic synthetic peptides based on nonstructural proteins of GBV-C/HGV. Journal of Peptide Science. 12(4), 267-78

Content: MORTIMER, CATRIONA G, WELLS, GEOFFREY, CROCHARD, JEAN-PHILIPPE, STONE, ERICA L, BRADSHAW, TRACEY D, STEVENS, MALCOLM F G and WESTWELL, ANDREW D, 2006. Antitumor benzothiazoles. 26.(1) 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potent and selective inhibitory activity against lung, colon, and breast cancer cell lines. Journal of Medicinal Chemistry. 49(1), 179-85

Content: SHAH, M., WELLS, G., BRADSHAW, T. D., LAUGHTON, C. A., STEVENS, M. F. G. and WESTWELL, A. D., 2006. Antitubercular Properties of Substituted Hydroxycyclohexadienones LETTERS IN DRUG DESIGN AND DISCOVERY. VOL 3(NUMB 6), 419-423

Content: LION, CEDRIC J, MATTHEWS, CHARLES S, WELLS, GEOFFREY, BRADSHAW, TRACEY D, STEVENS, MALCOLM F G and WESTWELL, ANDREW D, 2006. Antitumour properties of fluorinated benzothiazole-substituted hydroxycyclohexa-2,5-dienones ('quinols'). Bioorganic and Medicinal Chemistry Letters. 16(19), 5005-8

Content: AL-ANIZY, M., HORLEY, N.J., KUO, C.-W.S., GILLETT, L.C., LAUGHTON, C.A., KENDALL, D., BARRETT, D.A., PARKER, T. and BELL, D.R., 2006. Cytochrome P450 Cyp4x1 is a major P450 protein in mouse brain FEBS Journal. 273(5), 936-947

Content: HALL, GARETH, SHAH, MANISH, MCEWAN, PAUL A, LAUGHTON, CHARLES, STEVENS, MALCOLM, WESTWELL, ANDREW and EMSLEY, JONAS, 2006. Structure of Mycobacterium tuberculosis thioredoxin C. Acta Crystallographica. Section D: Biological Crystallography. 62(Pt 12), 1453-7

Content: WELLS, GEOFF, MARTIN, CHRISTOPHER R H, HOWARD, PHILIP W, SANDS, ZARA A, LAUGHTON, CHARLES A, TIBERGHIEN, ARNAUD, WOO, CHI KIT, MASTERSON, LUKE A, STEPHENSON, MARISSA J, HARTLEY, JOHN A and JENKINS, TEREN, 2006. Design, synthesis, and biophysical and biological evaluation of a series of pyrrolobenzodiazepine-poly(N-methylpyrrole) conjugates. Journal of Medicinal Chemistry. 49(18), 5442-61

Content: MEYER, T, FERRER-COSTA, C, PEREZ, A, RUEDA, M, BIDON-CHANAL, A, LUQUE, FJ, LAUGHTON, CA and OROZCO, M, 2006. Essential dynamics: A tool for efficient trajectory compression and management Journal of Chemical Theory and Computation. 2, 251-258

Content: HEWETT, PW, DAFT, EL, LAUGHTON, CA, AHMAD, S, AHMED, A and MURRAY, JC, 2006. Selective inhibition of the human Tie-1 promoter with triplex-forming oligonucleotides targeted to Ets binding sites Molecular Medicine. 12, 8-16

Content: NIKJOO, H, GIRARD, P, CHARLTON, D E, HOFER, K G and LAUGHTON, C A, 2006. Auger electrons--a nanoprobe for structural, molecular and cellular processes. Radiation Protection Dosimetry. 122(1-4), 72-9

Content: MURDOCK, S.E., TAI, K., NG, M.J., JOHNSTON, S., WU, B., FANGOHR, H., LAUGHTON, C.A., ESSEX, J.W. and SANSOM, M.S.P, 2006. Quality assurance for biomolecular simulations Journal of Chemical Theory and Computation. 2, 1477-1481

Content: COLLINS, H.M., KINDLE, K.B., MATSUDA, S., RYAN, C., TROKE, P.J.F., KALKHOVEN, E. and HEERY, D.M., 2006. MOZ-TIF2 alters cofactor recruitment and histone modification at the RARβ2 promoter: differential effects of MOZ fusion proteins on CBP- and MOZ-dependent activators Journal of Biological Chemistry. 281(25), 17124-17133

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