Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

Content: WARNER,, VADOLIA,, LAUGHTON,, KERR, and DOUGHTY,, 2007. Modelling the restoration of wild-type dynamic behaviour in DeltaF508-CFTR NBD1 by 8-cyclopentyl-1,3-dipropylxanthine. Journal of Molecular Graphics and Modelling. 26, 691-699

Content: MCCARROLL, A.J., BURKE, M.B., LAUGHTON, C.A. and STEVENS, M.F.G., 2007. Quinols as novel therapeutic agents. Part 8 Applications of the Sonogashira route to thioredoxin-inhibitory indolyl-substituted quinols. Arkivoc. 2007(xi), 172-182

Content: WANG, HAO and LAUGHTON, CHARLES A, 2007. Molecular modelling methods for prediction of sequence-selectivity in DNA recognition. Methods (San Diego, Calif.). 42(2), 196-203

Content: PÉREZ, ALBERTO, MARCHÁN, IVÁN, SVOZIL, DANIEL, SPONER, JIRI, CHEATHAM, THOMAS E, LAUGHTON, CHARLES A and OROZCO, MODESTO, 2007. Refinement of the AMBER force field for nucleic acids: improving the description of alpha/gamma conformers. Biophysical Journal. 92(11), 3817-29

Content: NOY, AGNES, PÉREZ, ALBERTO, LAUGHTON, CHARLES A and OROZCO, MODESTO, 2007. Theoretical study of large conformational transitions in DNA: the B<-->A conformational change in water and ethanol/water. Nucleic Acids Research. 35(10), 3330-8

Content: HARRIS, S. A. and LAUGHTON, C. A., 2007. A simple physical description of DNA dynamics: quasi-harmonic analysis as a route to the configurational entropy JOURNAL OF PHYSICS CONDENSED MATTER. VOL 19(NUMB 7), 076103

Content: MIDDLETON,R, BRIDDON,S.J., CORDEAUX,Y., YATES,A.S., DALE,C.L., GEORGE,M., BAKER,J.G., HILL,S.J. and KELLAM,B., 2007. New Fluorescent Adenosine A(1)-Receptor Agonists That Allow Quantification of Ligand-Receptor Interactions in Microdomains of Single Living Cells. Journal of Medicinal Chemistry. 50(4), 782-793

Content: CORDEAUX, Y., BRIDDON,S.J., ALEXANDER, S.P.H., KELLAM, B. and HILL, S.J., 2007. Agonist-occupied A3 adenosine receptors exist within heterogeneous complexes in membrane microdomains of individual living cells.The FASEB Journal FASEB. Available at: <http://www.fasebj.org/papbyrecent.dtl>

Content: DE BANK, P.A., HOU,Q., WARNER, R.M., WOOD, I.V., ALI, B.E., MACNEIL, S., KENDALL, D.A., KELLAM, B.K., SHAKESHEFF, K.M. and BUTTERY, L.D.K., 2007. Accelerated formation of multicellular 3-D structures by cell-to-cell cross-linking Biotechnology and Bioengineering. 97(6), 1617-1625

Content: BRIGGS, G.S., MCEWAN, P.A., YU, J., MOORE, T., EMSLEY, J. and LLOYD, R.G., 2007. Ring structure of the Escherichia coli DNA binding protein RdgC associated with recombination and replication fork repair Journal of Biological Chemistry. 282(17), 12353-12357

Content: ROSADO, C.J., BUCKLE, A.M., LAW, R.H.P., BUTCHER.R.E., KAN, W.-T., BIRD, C.H., UNG, K., BROWNE, K.A., BARAN, K., BASHTANNYK-PUHALOVICH, T.A., FAUX, N.G., WONG, W., PORTER, C.J., PIKE, R.N., ELLISDON, A.M., PEARCE, M.C., BOTTOMLEY, S.P., EMSLEY, J., SMITH, A.I., ROSSJOHN J., HARTLAND, E.L., VOSKOBOINIK, I., TRAPANI, J.A., BIRD, P.I., DUNSTONE, M.A. and WHISSTOCK, J.C., 2007. A common fold mediates vertebrate defense and bacterial attack. Science. 317(5844), 1548-1551

Content: HOOLEY, E, MCEWAN, P A and EMSLEY, J, 2007. Molecular modeling of the prekallikrein structure provides insights into high-molecular-weight kininogen binding and zymogen activation. Journal of Thrombosis and Haemostasis: JTH. 5(12), 2461-6

Content: CRISTIAN BELLODI, KARIN KINDLE, FRANCESCA BERNASSOLA, ANDREA COSSARIZZA,DAVID DINSDALE, GERRY MELINO, DAVID M. HEERY AND PAOLO SALOMONI, 2007. A cytoplasmic PML mutant inhibits p53 function. Cell Cycle. 5(22), 2688-2692

Content: EL-SHEIKH, S., GREEN, A.R., RAKHA, E.A., AHMED, R.A., PAIS, E.C., GRAINGE, M.J., BALL, G.R., ROBERTSON, J.F., HEERY, D.M. and ELLIS, I.O., 2007. Global histone modifications in breast cancer tissue correlate with tumor phenotype, prognostic factors and patient outcome EJC Supplements. 5(3), 14-14

Content: DAVID M HEERY & PETER M FISCHER, 2007. Pharmacological targeting of lysine acetyltransferases in human disease: a progress report Drug Discovery Today. 12(1-2), 88-99

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