School of Pharmacy

Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

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PARKHOUSE, SUSAN M, GARNETT, MARTIN C and CHAN, WENG C, 2008. Targeting of polyamidoamine-DNA nanoparticles using the Staudinger ligation: attachment of an RGD motif either before or after complexation. Bioorganic and Medicinal Chemistry. 16(13), 6641-50

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BRADSHAW, T.D., STONE, E.L., TRAPANI, V., LEONG, C.-O., MATTHEWS, C.S., TE POELE, R. and STEVENS, M.F.G., 2008. Mechanisms of acquired resistance to 2-(4-amino-3-methylphenyl)benzothiazole in breast cancer cell lines Breast Cancer Research and Treatment. 110(1), 57-68

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CHEW, E.H., LU, J., BRADSHAW, T.D. and HOLMGREN, A., 2008. Thioredoxin reductase inhibition by antitumor quinols: a quinol pharmacophore effect correlating to antiproliferative activity FASEB Journal. 22(6), 2072-2083

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AIELLO, S., WELLS, G., STONE, E.L., KADRI, H., BAZZI, R., BELL, D.R., STEVENS, M.F.G., MATTHEWS, C.S., BRADSHAW, T.D. and WESTWELL, A.D., 2008. Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (Pmx 610, Nsc 721648) Journal of Medicinal Chemistry. 51(16), 5135-5139

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WITHERS, I.M., MAZANETZ, M.P., WANG, H., FISCHER, P.M. and LAUGHTON, C.A., 2008. Active site pressurization: a new tool for structure-guided drug design and other studies of protein flexibility Journal of Chemical Information and Modeling. 48(7), 1448-1454

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MAZANETZ, M.P., WITHERS, I.M., LAUGHTON, C.A. and FISCHER, P.M., 2008. Exploiting glycogen synthase kinase 3beta flexibility in molecular recognition. Biochemical Society Transactions. 36(1), 55-58

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LIVERPOOL, T.B., HARRIS, S.A. and LAUGHTON, C.A., 2008. Supercoiling and denaturation of DNA loops Physical Review Letters. 100(23), 238103

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LAUGHTON, CHARLES A, LUISI, BEN F, PRATAP, J VENKATESH and CALLADINE, CHRIS R, 2008. A potential molecular switch in an alpha-helical coiled coil. Proteins. 70(1), 25-30

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JIRANUSORNKUL, SUPAT and LAUGHTON, CHARLES A, 2008. Destabilization of DNA duplexes by oxidative damage at guanine: implications for lesion recognition and repair. Journal Of The Royal Society Interface. 5 Suppl 3, S191-8

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GIRARD, PETER M, NIKJOO, HOOSHANG and LAUGHTON, CHARLES, 2008. Simulation of (125)I-based radioprobing experiments to study DNA quadruplex structure and topology. International Journal of Radiation Biology. 84(12), 1045-9

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CHENG, MAI-KIM, MODI, CHETNA, COOKSON, JENNIFER C, HUTCHINSON, IAN, HEALD, ROBERT A, MCCARROLL, ANDREW J, MISSAILIDIS, SOTIRIS, TANIOUS, FARIAL, WILSON, W DAVID, MERGNY, JEAN-LOUIS and LAUGHTON, CHARLES, 2008. Antitumor polycyclic acridines. 20. Search for DNA quadruplex binding selectivity in a series of 8,13-dimethylquino[4,3,2-kl]acridinium salts: telomere-targeted agents. Journal of Medicinal Chemistry. 51(4), 963-75

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HARRIS, S.A., LAUGHTON, C.A. and LIVERPOOL, T.B., 2008. Mapping the phase diagram of the writhe of DNA nanocircles using atomistic molecular dynamics simulations Nucleic Acids Research. 36(1), 21-29

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CORDEAUX, Y., BRIDDON, S.J., ALEXANDER, S.P.H., KELLAM, B. and HILL, S.J., 2008. Agonist-occupied A3 adenosine receptors exist within heterogeneous complexes in membrane microdomains of individual living cells FASEB Journal. 22(3), 850-860

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HOOLEY, ELIZABETH, PAPAGRIGORIOU, EVANGELOS, NAVDAEV, ALEXEI, PANDEY, AMIT V, CLEMETSON, JEANNINE M, CLEMETSON, KENNETH J and EMSLEY, JONAS, 2008. The crystal structure of the platelet activator aggretin reveals a novel (alphabeta)2 dimeric structure. Biochemistry. 47(30), 7831-7

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ZIEGLER, WOLFGANG H, GINGRAS, ALEX R, CRITCHLEY, DAVID R and EMSLEY, JONAS, 2008. Integrin connections to the cytoskeleton through talin and vinculin. Biochemical Society transactions. 36(Pt 2), 235-9
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School of Pharmacy

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