School of Pharmacy

Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

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BAKER, J.G., PROUDMAN, R.G.W., HAWLEY, N.C., FISCHER, P.M. and HILL, S.J., 2008. Role of key transmembrane residues in agonist and antagonist actions at the two conformations of the human β1-adrenoceptor Molecular Pharmacology. 74(5), 1246-1260

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HUBER, K., PATEL, P., ZHANG, L., EVANS, H., WESTWELL, A.D., FISCHER, P.M., CHAN, S. and MARTIN, S., 2008. 2-[(1-Methylpropyl)dithio]-1H-imidazole inhibits tubulin polymerization through cysteine oxidation Molecular Cancer Therapeutics. 7(1), 143-151

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WANG, S. and FISCHER, P.M., 2008. Cyclin-dependent kinase 9: a key transcriptional regulator and potential drug target in oncology, virology and cardiology Trends in Pharmacological Sciences. 29(6), 302-313

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PATWARDHAN, G, OLDHAM, N.J. and FISCHER, P.M., 2008. Structure-guided design of inhibitors of the eukaryotic initiation factor 4E (eIF4E) mRNA-cap interaction as anti-cancer agents In: European Journal of Cancer Supplements, Volume 6, Issue 9. 106 (In Press.)

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FISCHER, P.M., 2008. Computational chemistry approaches to drug discovery in signal transduction Biotechnology Journal. 3(4), 452-470

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FISCHER, P.M., 2008. Turning down tau phosphorylation Nature Chemical Biology. 4(8), 448-449

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FISCHER, P.M., 2008. Cell cycle inhibitors in cancer: current status and future directions. In: NEIDLE, S., ed., Cancer Drug Design and Discovery Academic Press. 253-283

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DEKKER, L.V., 2008. Novel approaches to drug discovery in signal transduction The Biotechnology Journal. 3(4), 428-429

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ASHRAF, S. and WALSH, D. A., 2008. Angiogenesis in osteoarthritis Curr Opin Rheumatol. 20(5), 573-80

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STONEHOUSE, JP, CHEKMAREV, DS, IVANOVA, NV, LANG, S, PAIRAUDEAU, G, SMITH, N, STOCKS, MJ, SVIRIDOV, SI and UTKINA, LM, 2008. One-pot four-component reaction for the generation of pyrazoles and pyrimidines Synlett. 100-104

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WILLIAMS, P., WINZER, K., CHAN, W.C. and CAMARA, M., 2007. Look who's talking: communication and quorum sensing in the bacterial world Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 362, 1119-1134

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ABUKHADER, MAJED M, HEAP, JOHN, DE MATTEIS, CRISTINA I, DOUGHTY, STEPHEN W, MINTON, NIGEL and PAOLI, MAX, 2007. Crystallization and preliminary X-ray characterization of the Bacillus amyloliquefaciens YwrO enzyme. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 63(Pt 9), 746-50

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REID, SD, WILSON, C, DE MATTEIS, CI and LOVE, JB, 2007. Using chiral ligand substituents to promote the formation of dinuclear, double-stranded iron, manganese, and zinc mesocates European Journal of Inorganic Chemistry. 33, 5286-5293

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ATHANASIOU, ANDRIANI, CLARKE, ANNA B, TURNER, AMY E, KUMARAN, NETHIA M, VAKILPOUR, SARA, SMITH, PAUL A, BAGIOKOU, DIMITRA, BRADSHAW, TRACEY D, WESTWELL, ANDREW D, FANG, LIN, LOBO, DILEEP N and CONSTANTIN, 2007. Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochemical and biophysical research communications. 364(1), 131-7

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MCCARROLL, ANDREW J, BRADSHAW, TRACEY D, WESTWELL, ANDREW D, MATTHEWS, CHARLES S and STEVENS, MALCOLM F G, 2007. Quinols as novel therapeutic agents. 7.1 Synthesis of antitumor 4-[1-(arylsulfonyl-1H-indol-2-yl)]-4-hydroxycyclohexa-2,5-dien-1-ones by Sonogashira reactions. Journal of Medicinal Chemistry. 50(7), 1707-10
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School of Pharmacy

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