School of Pharmacy

Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

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SEVILLE, LUCY L, SHAH, NITA, WESTWELL, ANDREW D and CHAN, WENG C, 2005. Modulation of pRB/E2F functions in the regulation of cell cycle and in cancer. Current Cancer Drug Targets. 5(3), 159-70

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ZHELEVA, D.L., FISCHER, P.M., MCINNES, C., ANDREWS, M.J.I., CHAN, W.C. and ATKINSON, G.E., 2005. Cyclin binding peptides, and their use in drug screening assays WO 2005/040802 A3 05/06/2005 00:00:00

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ABUKHADER, M., HEAP, J., DE MATTEIS, C., KELLAM, B., DOUGHTY, S.W., MINTON, N. and PAOLI, M., 2005. Binding of the anticancer prodrug CB1954 to the activating enzyme NQ02 revealed by the crystal structure of their complex Journal of Medicinal Chemistry. 48(24), 7714-7719

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BRADSHAW, T.D., MATTHEWS, C.S., COOKSON, J., CHEW, E.-H., SHAH, M., BAILEY, K., MONKS, A., HARRIS, E., WESTWELL, A.D., WELLS, G., LAUGHTON, C.A. and STEVENS, M.FG., 2005. Elucidation of thioredoxin as a molecular target for antitumor quinols Cancer Research. 65(9), 3911-3919

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MUKHERJEE, A., WESTWELL, A.D., BRADSHAW, T.D., STEVENS, M.F.G., CARMICHAEL, J. and MARTIN, S.G., 2005. Cytotoxic and antiangiogenic activity of AW464 (NSC 706704), a novel thioredoxin inhibitor: an in vitro study British Journal of Cancer. 92, 350-358

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BERRY, J.M., BRADSHAW, T.D., FICHTNER, I., REN, R., SCHWALBE, C.H., WELLS, G., CHEW, E.-H., STEVENS, M.F.G. and WESTWELL, A.D., 2005. Quinols as novel therapeutic agents. 2. 4-(1-arylsulfonylindol-2-yl)-4-hydroxycyclohexa-2,5-dien-1-ones and related agents as potent and selective antitumor agents Journal of Medicinal Chemistry. 48(2), 639-644

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BRADSHAW,T.D., MORTIMER,C.G. and WESTWELL,A.D., 2005. Update to: the aryl hydrocarbon receptor in anticancer drug discovery: friend or foe? Medicinal Chemistry Reviews - Online. 2(2), 153-161

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FURMONAVICIENE, R., SUTTON, B.J., GLASER, F., LAUGHTON, C.A., JONES, N., SEWELL, H.F. and SHAKIB, F., 2005. An attempt to define allergen-specific molecular surface features: a bioinformatic approach Bioinformatics. 21(23), 4201-4204

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BARRATT, ELIZABETH, BINGHAM, RICHARD J, WARNER, DANIEL J, LAUGHTON, CHARLES A, PHILLIPS, SIMON E V and HOMANS, STEVE W, 2005. Van der Waals interactions dominate ligand-protein association in a protein binding site occluded from solvent water. Journal of the American Chemical Society. 127(33), 11827-34

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MISSAILIDIS, SOTIRIS, MODI, CHETNA, TRAPANI, VALENTINA, LAUGHTON, CHARLES A and STEVENS, MALCOLM F G, 2005. Antitumor polycyclic acridines. Part 16. Triplex DNA as a target for DNA-binding polycyclic acridine derivatives. Oncology Research. 15(2), 95-105

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JHA, SHANTENU, COVENEY, PETER V and LAUGHTON, CHARLES A, 2005. Force field validation for nucleic acid simulations: comparing energies and dynamics of a DNA dodecamer. Journal of Computational Chemistry. 26(15), 1617-27

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MALHAM, RICHARD, JOHNSTONE, SARAH, BINGHAM, RICHARD J, BARRATT, ELIZABETH, PHILLIPS, SIMON E V, LAUGHTON, CHARLES A and HOMANS, STEVE W, 2005. Strong solute-solute dispersive interactions in a protein-ligand complex. Journal of the American Chemical Society. 127(48), 17061-7

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YATES, A.S., DOUGHTY, S.W., KENDALL, D.A. and KELLAM, B., 2005. Chemical modification of the naphthoyl 3-position of JWH-015: in search of a fluorescent probe to the cannabinoid CB2 receptor Bioorganic & Medicinal Chemistry Letters. 15(16), 3758-3762
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