School of Pharmacy

Publications in the Biomolecular Science and Medicinal Chemistry Division

Publications

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NUTLEY, B.P., RAYNAUD, F.I., WILSON, S.C., FISCHER, P.M., HAYES, A., GODDARD, P.M., MCCLUE, S.J., JARMAN, M., LANE, D.P. and WORKMAN, P., 2005. Metabolism and pharmacokinetics of the cyclin-dependent kinase inhibitor R-roscovitine in the mouse. Molecular Cancer Therapeutics. 4(1), 125-139

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UHRINOVA, S., UHRIN, D., POWERS, H., WATT, K., ZHELEVA, D., FISCHER, P.M., MCINNES, C. and BARLOW, P.N., 2005. Structure of free MDM2 N-terminal domain reveals conformational adjustments that accompany p53-binding. Journal of Molecular Biology. 350(3), 587-598

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DEKKER, LODEWIJK V, DANIELS, ZOE, HICK, CAROLINE, ELSEGOOD, KATHRYN, BOWDEN, SARAH, SZESTAK, TADGE, BURLEY, J RUSSELL, SOUTHAN, ANDY, CRONK, DAVID and JAMES, IAIN F, 2005. Analysis of human Nav1.8 expressed in SH-SY5Y neuroblastoma cells. European Journal of Pharmacology. 528(1-3), 52-8

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BROWN, SEAN G, THOMAS, ALISON, DEKKER, LODEWIJK V, TINKER, ANDREW and LEANEY, JOANNE L, 2005. PKC-delta sensitizes Kir3.1/3.2 channels to changes in membrane phospholipid levels after M3 receptor activation in HEK-293 cells. American Journal of Physiology: Cell Physiology. 289(3), C543-56

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RENAULT, MARIE-ANGE, JALVY, SANDRA, POTIER, MYLèNE, BELLOC, ISABELLE, GENOT, ELISABETH, DEKKER, LODEWIJK V, DESGRANGES, CLAUDE and GADEAU, ALAIN-PIERRE, 2005. UTP induces osteopontin expression through a coordinate action of NFkappaB, activator protein-1, and upstream stimulatory factor in arterial smooth muscle cells. Journal of Biological Chemistry. 280(4), 2708-13

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DEKKER,L.V. and CRONK,D., 2005. Nav1.8 as a drug target for pain. In: COWARD,K. and BAKER,M.D., eds., Sodium channels, pain and analgesia Birkhäuser Publishing Ltd, Basel, CHE. 123-144

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NEBBIOSO, A., CLARKE, N., VOLTZ, E., GERMAIN, E., AMBROSINO, C., BONTEMPO, P., ALVAREZ, R., SCHIAVONE, E.M., FERRARA, F., BRESCIANI, F., WEISZ, A., DE LERA, A.R., GRONEMEYER, H. and ALTUCCI, L., 2005. Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells Nature Medicine. 11(1), 77-84

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CLARKE, N., NEBBIOSO, A., ALTUCCI, L. and GRONEMEYER, H., 2005. TRAIL: at the center of drugable anti-tumor pathways Cell Cycle. 4(7), 914-918

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ALTUCCI, LUCIA, CLARKE, NICOLE, NEBBIOSO, ANGELA, SCOGNAMIGLIO, ANNAMARIA and GRONEMEYER, HINRICH, 2005. Acute myeloid leukemia: therapeutic impact of epigenetic drugs. International Journal of Biochemistry and Cell Biology. 37(9), 1752-62

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MULDER, KLAAS W, WINKLER, G SEBASTIAAN and TIMMERS, H TH MARC, 2005. DNA damage and replication stress induced transcription of RNR genes is dependent on the Ccr4-Not complex. Nucleic acids research. 33(19), 6384-92

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WINKLER, G SEBASTIAAN and TIMMERS, H TH MARC, 2005. Structure-based approaches to create new e2-e3 enzyme pairs. Methods in enzymology. 399, 355-66

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BOURQUE, E, KOCIENSKI, PJ, STOCKS, M and YUEN, J, 2005. Synthesis of the c14-c28 fragment of tetronasin Synthesis-Stuttgart. 3219-3224

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STOCKS, MJ, BARBER, S, FORD, R, LEROUX, F, ST-GALLAY, S, TEAGUE, S and XUE, YF, 2005. Structure-driven htl: Design and synthesis of novel aminoindazole inhibitors of c-jun n-terminal kinase activity Bioorganic & Medicinal Chemistry Letters. 15(14), 3459-3462

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FALSONE, S. F., GESSLBAUER, B., TIRK, F., PICCININI, A. M. and KUNGL, A. J., 2005. A proteomic snapshot of the human heat shock protein 90 interactome: FEBS Lett FEBS Lett. 579(28), 6350-4
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