Publications in the Biomolecular Science and Medicinal Chemistry Division

Content: SOU, TOMAS, KUKAVICA-IBRULJ, IRENA, SOUKARIEH, FADI, HALLIDAY, NIGEL, LEVESQUE, ROGER C, WILLIAMS, PAUL, STOCKS, MICHAEL, CAMARA, MIGUEL, FRIBERG, LENA E and BERGSTROM, CHRISTEL A S, 2018. Model-based drug development in pulmonary delivery: Pharmacokinetic analysis of novel drug candidates for treatment of Pseudomonas aeruginosa lung infection. Journal of pharmaceutical sciences.

Content: SOUKARIEH, FADI, WILLIAMS, PAUL, STOCKS, MICHAEL JOHN and CAMARA, MIGUEL., 2018. Pseudomonas aeruginosa Quorum Sensing Systems as Drug Discovery Targets: Current Position and Future Perspectives. Journal of Medicinal Chemistry. Ahead of Print

Content: LEE, JONG BONG, ZGAIR, ATHEER, MALEC, JED, KIM, TAE HWAN, KIM, MIN GI, ALI, JOSEPH, QIN, CHAOLONG, FENG, WANSHAN, CHIANG, MANTING, GAO, XIZHE, VORONIN, GREGORY, GARCES, AIMIE E, LAU, CHUN LONG, CHAN, TING-HOI, HUME, AMY, MCINTOSH, TECASHANELL M, SOUKARIEH, FADI, AL-HAYALI, MOHAMMED, CIPOLLA, ELENA, COLLINS, HILARY M, HEERY, DAVID M, SHIN, BEOM SOO, YOO, SUN DONG, KAGAN, LEONID, STOCKS, MICHAEL J, BRADSHAW, TRACEY D, FISCHER, PETER M and GERSHKOVICH, PAVEL., 2018. Lipophilic activated ester prodrug approach for drug delivery to the intestinal lymphatic system. Journal of Controlled Release. 286, 10-19

Content: GARCES, AIMIE E and STOCKS, MICHAEL J, 2018. Class 1 PI3K Clinical Candidates and Recent Inhibitor Design Strategies: A Medicinal Chemistry Perspective. Journal of Medicinal Chemistry. Ahead of Print

Content: MINHAS, HARSIMRAN K., RILEY, WILLIAM, STUART, ALISON M. and URBONAITE, MARTYNA, 2018. Activation of the hypervalent fluoroiodane reagent by hydrogen bonding to hexafluoroisopropanol ORGANIC & BIOMOLECULAR CHEMISTRY. 16(39), 7170-7173

Content: FYFE, TJ, ZARZYCKA, B, LIM, HD, KELLAM, B, MISTRY, SN, KATRICH, V, SCAMMELLS, PJ, LANE, JR and CAPUANO, B, 2018. A Thieno[2,3-d]pyrimidine Scaffold is a Novel Negative Allosteric Modulator of the Dopamine D2 Receptor Journal of Medicinal Chemistry. 62(1), 174-206

Content: VAN DER WESTHUIZEN, ET, SPATHIS, A, KHAJEHALI, E, JORG, M, MISTRY, SN, CAPUANO, B, TOBIN, AB, SEXTON, PM, SCAMMELLS, PJ, VALANT, C and CHRISTOPOULOS, A, 2018. Assessment of the molecular mechanisms of action of novel 4-phenylpyridine-2-one and 6-phenylpyrimidin-4-one allosteric modulators at the M1 muscarinic acetylcholine receptor Molecular Pharmacology. (In Press.)

Content: ALCOBIA, DIANA C., ZIEGLER, ALEXANDRA, I, KONDRASHOV, ALEXANDER, COMEO, ELEONORA, MISTRY, SARAH, KELLAM, BARRIE, CHANG, AESON, WOOLARD, JEANETTE, HILL, STEPHEN J. and SLOAN, ERICA K., 2018. Visualizing Ligand Binding to a GPCR In Vivo Using NanoBRET ISCIENCE. 6, 280-+

Content: TAREK ABOUL-FADL, AHMED S. M. ABORAIA, ABU-BAKER M. ABDEL-AAL, MOHAMMED K. ABDEL-HAMID, WESAM S. QAYED, OLA M. F. ABOU-GHADIR, MARIAM E. I. ABDEL-RASOUL, RANA M. IBRAHIM, MOSTAFA A. HASSAN, NOHA G. M. FEKRY, HEND A.A. ABD EL-WAHAB and ADEL F. YOUSSEF, 2018. Modified Lidocaine Derivatives as a Potential Inhibitors of Eosinophils In: 2nd International Congress and Exhibition on Pharmacy (Pharmacy-2018), Paris, Farnce, August 20-21, 2018.

Content: ZAMBERLAN, F., TURYANSKA, L., PATANE, A., LIU, Z., WILLIAMS, H. E. L., FAY, M. W., CLARKE, P. A., IMAMURA, Y., JIN, T., BRADSHAW, T. D., THOMAS, N. R. and GRABOWSKA, A. M., 2018. Stable DHLA-PEG capped PbS quantum dots: from synthesis to near-infrared biomedical imaging: Journal of Materials Chemistry B Journal of Materials Chemistry B. 6(4), 550-555

Content: BIN BREAK, MOHAMMED KHALED, HOSSAN, MD SHAHADAT, KHOO, YIVONN, QAZZAZ, MOHANNAD EMAD, AL-HAYALI, MOHAMMED Z. K., CHOW, SEK CHUEN, WIART, CHRISTOPHE, BRADSHAW, TRACEY D., COLLINS, HILARY and KHOO, TENG-JIN, 2018. Discovery of a highly active anticancer analogue of cardamonin that acts as an inducer of caspase-dependent apoptosis and modulator of the mTOR pathway FITOTERAPIA. 125, 161-173

Content: SANTOS, MARILIA S., NORTCLIFFE, ANDREW, LEWIS, WILLIAM, BRADSHAW, TRACEY D. and MOODY, CHRISTOPHER J., 2018. Synthesis of Highly Substituted 1,2-Diazetidin-3-ones, Small-Ring Scaffolds for Drug Discovery CHEMISTRY-A EUROPEAN JOURNAL. 24(33), 8325-+

Content: COUSIN, DAVID, HUMMERSONE, MARC G., BRADSHAW, TRACEY D., ZHANG, JIHONG, MOODY, CHRISTOPHER J., FOREITER, MAGDALENA B., SUMMERS, HELEN S., LEWIS, WILLIAM, WHEELHOUSE, RICHARD T. and STEVENS, MALCOLM F. G., 2018. Synthesis and growth-inhibitory activities of imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamides related to the anti-tumour drug temozolomide, with appended silicon, benzyl and heteromethyl groups at the 3-position MEDCHEMCOMM. 9(3), 545-553

Content: CITOSSI, FRANCESCA, SMITH, THOMAS, LEE, JONG BONG, SEGAL, JOEL, GERSHKOVICH, PAVEL, STOCKS, MICHAEL J., BRADSHAW, TRACEY D., KELLAM, BARRIE and MARLOW, MARIA, 2018. Self-Assembling Benzothiazole-Based Gelators: A Mechanistic Understanding of in Vitro Bioactivation and Gelation MOLECULAR PHARMACEUTICS. 15(4), 1578-1586

Content: SMEDLEY, CHRISTOPHER J., STANLEY, PAUL A., QAZZAZ, MOHANNAD E., PROTA, ANDREA E., OLIERIC, NATACHA, COLLINS, HILARY, EASTMAN, HARRY, BARROW, ANDREW S., LIM, KUAN-HON, KAM, TOH-SEOK, SMITH, BRIAN J., DUIVENVOORDEN, HENDRIKA M., PARKER, BELINDA S., BRADSHAW, TRACEY D., STEINMETZ, MICHEL O. and MOSES, JOHN E., 2018. Sustainable Syntheses of (-)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site SCIENTIFIC REPORTS. 8,

Publications