Our groundbreaking research into the fundamental mechanisms of cell physiology and pathology helps to drive our understanding of disease – and our ability to tackle it.
Here in the Division of Physiology, Pharmacology and Neuroscience, we investigate many fundamental aspects of cell function, including metabolism, gene expression, protein ubiquitination, membrane transport, cytoskeletal structure, and organelle translocation.
These processes regulate cell proliferation, morphology, differentiation, autophagy, apoptosis, drug resistance and more. By understanding them in greater depth, we can gain important insights into disease processes and make significant steps towards new treatments. As a team, we’re particularly interested in cancer, Paget’s disease, skeletal muscle atrophy and neurodegeneration.
Our work is funded by Cancer Research UK, the Medical Research Council, and the Motor Neurone Disease Association.