Neuroscience

Integrative, collaborative research is at the heart of the Division of Physiology, Pharmacology and Neuroscience, and our neuroscience research embodies this principle. Our team’s investigations range from the study of single molecules all the way through to in vivo imaging, electrophysiology and behavioural studies.

Together, we’re exploring many fascinating aspects of neuroscience. Our programmes are focused on understanding fundamental aspects of neuronal development and healthy brain ageing, as well as investigating how normal function is disrupted in common neurological disorders. We have particular interests in the mechanisms underlying pain, neurodegenerative disease, addiction, schizophrenia, dementia and stroke.

Our work receives substantial funding from Arthritis Research UK, who support our Centre of Excellence in Arthritis Pain, as well as the Biotechnology and Biological Sciences Research Council, EU FP7, Medical Research Council, National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), the Leverhulme Trust, and the Wellcome Trust.

Research that's making an impact

World-leading research into musculoskeletal health

Tackling chronic arthritic pain

We’re home to the pre-clinical laboratories of the Arthritis Research UK Pain Centre. There, our researchers are leading the way in understanding the mechanistic basis of chronic pain, which can have a devastating impact on arthritis patients’ quality of life.

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A new class of small molecule inhibitors

The University of Nottingham spinout company Exonate, co-founded by Professor Lucy Donaldson, is developing a range of small molecule inhibitors to regulate alternative gene splicing. Already tested in the treatment of macular degeneration, they have far-reaching potential.